Basic Information

Insect: Drosophila kambysellisi
Gene Symbol: -
Assembly: GCA_035042185.1
Location: JAWNLS010000946.1:1718875-1722835[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.65 45 4.8 4.0 2 23 367 389 366 389 0.96

2 17 9 6.3e+02 1.2 0.1 1 23 396 421 396 421 0.88

3 17 0.019 1.3 9.7 1.8 2 23 432 453 432 453 0.93

4 17 5.9 4.1e+02 1.8 3.0 2 17 464 479 463 490 0.75

5 17 0.026 1.8 9.2 0.3 3 23 523 543 521 543 0.95

6 17 0.0014 0.1 13.2 0.2 1 23 551 574 551 574 0.98

7 17 3.5e-05 0.0024 18.3 0.2 2 23 579 600 578 600 0.97

8 17 0.00026 0.018 15.5 0.2 1 22 648 669 648 672 0.91

9 17 0.27 19 6.0 3.3 1 21 677 697 677 698 0.94

10 17 0.013 0.94 10.1 0.6 1 23 717 742 717 742 0.96

11 17 0.012 0.85 10.3 1.4 2 23 758 780 757 780 0.93

12 17 0.0064 0.45 11.1 0.4 2 23 786 808 785 808 0.92

13 17 0.0037 0.26 11.9 0.1 2 23 812 834 811 834 0.96

14 17 1.4e-05 0.00096 19.5 2.2 1 23 840 862 840 862 0.98

15 17 0.0016 0.11 13.0 0.8 1 23 866 889 866 889 0.93

16 17 0.00014 0.0095 16.4 1.6 1 23 895 918 895 918 0.97

17 17 0.004 0.28 11.8 0.2 1 23 922 950 922 950 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.65	45	4.8	4.0	2	23	367	389	366	389	0.96
2	17	9	6.3e+02	1.2	0.1	1	23	396	421	396	421	0.88
3	17	0.019	1.3	9.7	1.8	2	23	432	453	432	453	0.93
4	17	5.9	4.1e+02	1.8	3.0	2	17	464	479	463	490	0.75
5	17	0.026	1.8	9.2	0.3	3	23	523	543	521	543	0.95
6	17	0.0014	0.1	13.2	0.2	1	23	551	574	551	574	0.98
7	17	3.5e-05	0.0024	18.3	0.2	2	23	579	600	578	600	0.97
8	17	0.00026	0.018	15.5	0.2	1	22	648	669	648	672	0.91
9	17	0.27	19	6.0	3.3	1	21	677	697	677	698	0.94
10	17	0.013	0.94	10.1	0.6	1	23	717	742	717	742	0.96
11	17	0.012	0.85	10.3	1.4	2	23	758	780	757	780	0.93
12	17	0.0064	0.45	11.1	0.4	2	23	786	808	785	808	0.92
13	17	0.0037	0.26	11.9	0.1	2	23	812	834	811	834	0.96
14	17	1.4e-05	0.00096	19.5	2.2	1	23	840	862	840	862	0.98
15	17	0.0016	0.11	13.0	0.8	1	23	866	889	866	889	0.93
16	17	0.00014	0.0095	16.4	1.6	1	23	895	918	895	918	0.97
17	17	0.004	0.28	11.8	0.2	1	23	922	950	922	950	0.89

Sequence Information

Coding Sequence: ATGtcggaaaatgtaaaaactgACGAAAATGTGCCTAGCTGCCTGCATTGCAGAGTGTacaattcaaaacaaaaataccatGAGATTTTCGACGAAGTCGGCATCGAAATAGAGCTCGCCAAACTGCTGCACAAGTATTTCGAGATAAAAGTTGAGCCAACTAACCAAAAACAGAAGCAACTGCTATGCGAGGAGTGCGTTAATACGCTGATTCGATTCTTTGACATCGACGAACTGCAAAGGGAGCAAGATGCCGCAAATGCTGTAACTAAAAAGCGGACTAACGATACAAAGTCTTCTGCCCCCGAAAAAGATGAAAATCCCGCCAAAAAGCAGAGAACTGCCGCAAAAAATGGCCAAGGTTCACCAAACTCCTCGGCAAATGAAGCCACAAAGCAAGATACGTCTACGGCGGCTTCTGCTGAAACTGCTACTGCTGAAACTACTACTGCTAAAACTGCTACGACTGATCCTGCCCCTGATCCTATTGCAAAAGGAGCGCCAGAAGCCCTTGGCATACGCATCATCAGAGCCAGCAACACATCGCCAAAAAGATTGCCCATAAATGTGAAGAAAGCAGTCGAGCGAAGTGAAACACTTAAGGGCAAAGCCGGCGTCAAACGGCGTCGGTCCAGAGATGTTGCTCATGGATCAGGAGATCAGGAGCAGATTAGCGCACTTATACGTGACATTCTAGAGGATGAGGAGACGCCAGCGGATGAAAAATTGGTAGAAGCAGCCGCCACAGTCCGACAGCTAGAGAAACAATCTGCTGAAGAGCAATGCCATCTAGAGGAGGCGGTGGAAGAGGAGCAAGCGGTGCTCGAGGACCAGGACAATAATGATGAGCTGGAGTTTCTGGTTGAGCGTGAAGATAGCTCCTCTGAATTGAGCGTGCGCCATTTCAAATTGGAGCGAAAAATTAAACGCGCCCCATCACAGTCACAAAATGAGAGCCAAAGCGAGGATGAAGCATTCAAAGTGGAGCCCTTCAATTTTGTACTGATCAAGGAATCTGATAACATTGACGATCTATACGAGTATTTGGGAACCGTGGTGAAGACCTGTTTTGAGACTTTGATGTTCGACTGGGACACTGTGTGCCGCCACTGTTCGTTAAAGTGTAGCAAATATGAAAGTTTACTCGGTCACATGCTGAAGCTTCACAAGGAGCAGGGCGAGATTTACAAGTGCCCGATTACCGAATGCACGGCAGAGCTACACGGAGCTAAATCCTTGGCCATGCACCTGGTTGTGCTGCATGCGCCGGTAGCCGATATCCCCATTTATGGCAGTTGTCCCGAATGCAACATGACCTTCTCAAACATATTGCAGTACAACAAGCACTCCTGCGCGCATGTCATCAAAAAGCGTCGCGGCATACGCCTGTATTGTGAGATGTGCGGCCTGGAGTTCCCCTCATGGAAGCGCTTTAATTTTCACAATCAATTTCATTTGGAGCGTCACAGGCCGCGCGCCTGCTTTGTGTGCAGCTACGCGGATACCAACATCGATGAGCTGTTCCATCATTTGCACTACGCTCACGAGCCAGAGGGCACCCTTTTCTGTGATCTATGTGATCGAAATTTTCGTGATCCTGCCGTCTTTTTGGAGCACAACAAATCACACTCAAATGTCAGCAGTACCACCTACAGCTGCACCGAGTGTAGCGCCAATTTTGAGTCACGTGGTCGCCTCAATGGACACCTGcGCACCGCACATGGCAGCGTCATCAGCTGCGAAATGTGCGGTCGCGAATTTGCCACGGAGGCCACCTACAACCTGCACATGAAAACGCATCTGATTATTGAACGCGAGGTGCATGTGTGCAACAATTGCGGTCTACTCAGCGAATATAATGACAGGATGCTGGCTCATGTGGCGGATGAGGATTCGGGTTGCTTTGGCATGGATGTGGTAGTGGAACTGATGCGTGATGCTTATGTTTGTGAATATTGCTCCGCCTATTTTAAGCAGAAGAGTGATTTAAGCGCCCATCGCGCTTCGGGGGTGCACAAGGATGGCGAGTTCTATTGTCAGCCTTGCCGCAAAAAGTTTACCGATATGAAGCTCTATCGTCACCACTTGCGCAACTATCAACAATTGCGCACAGACTTTTCGCATCGCCGACTAGAAATTTGTCTCCACTACATGTGCGATTATGAGAATTGCAGTGAGGCCTATATTAATTGGAATTCGCTATACACGCACAAGCGGCGCACACACGATGCCGTCGAGAAGCAGGAGCCCAAGATAAAAAATAGCGAATGGATCTGTCAGTTCTGTCAGAAAGTGTGCCGCTCCAAAATGTCGCTCTCGGTTCACGTAGCGCGCAGTCACAACAACAATAATGTGGTCTGCTCGCTGTGCAAAGCTTCGTATAAGGATGAGGAGGCGCTAAAAAAGCATCACGCCTATTGGCATGAGCGCATAGAGTGCCCGATGTGCTTGAAGGTGGTGAAGAATCGGCGCAACTATGACACCCACATAAAGGTGGTGCACTCAAACAATAAGCGTTACTCGTGCAGTGAATGCCAAAAGGGTTTCTATCACAAGAGCGAAATGGAGGCGCATCAGCGGCTGCATTCGCAATCGTTTAAATGCGAACAGTGCAACTTCACCACGAGGAACAAGAAGTCGCTGGCGGTTCATGTGCTTGGCCAGCACTACAAGCGTTTTGCCTTCAAGTGTAAGTTCTGCGATAAGCGCTTTGGACGCCGCCAGGGACTGTCGAATCATGTTCTACGTGTGCATAGCTCGAAATACACATGTCGTGACTTCTTCGATGGCGGTTGTGGCAAATCATTTGGCTCGACGGCACGGCTCAATGTGCATGTGCGAAAGGTGCATAACAGCAGCCTCATTCTGTCCGATGACCCAGCCAAATTGGAAGACAacgaagaggaggaggaggaggaggaggtacAGGCTTTTGAAGGTCCGTCCACATCTAATGCGAATACTGAGATTGAATTTATTGCCGATGACGACAATGAGAATCTGACTGATTCGGAAATCATCGAAGAGATTCCAGAGAGAAAACCAGTAACTCGGCAACCTCGAAAAACTAAACCAAAGCCAATGACAACGCGAGCTTGA
Protein Sequence: MSENVKTDENVPSCLHCRVYNSKQKYHEIFDEVGIEIELAKLLHKYFEIKVEPTNQKQKQLLCEECVNTLIRFFDIDELQREQDAANAVTKKRTNDTKSSAPEKDENPAKKQRTAAKNGQGSPNSSANEATKQDTSTAASAETATAETTTAKTATTDPAPDPIAKGAPEALGIRIIRASNTSPKRLPINVKKAVERSETLKGKAGVKRRRSRDVAHGSGDQEQISALIRDILEDEETPADEKLVEAAATVRQLEKQSAEEQCHLEEAVEEEQAVLEDQDNNDELEFLVEREDSSSELSVRHFKLERKIKRAPSQSQNESQSEDEAFKVEPFNFVLIKESDNIDDLYEYLGTVVKTCFETLMFDWDTVCRHCSLKCSKYESLLGHMLKLHKEQGEIYKCPITECTAELHGAKSLAMHLVVLHAPVADIPIYGSCPECNMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCSYADTNIDELFHHLHYAHEPEGTLFCDLCDRNFRDPAVFLEHNKSHSNVSSTTYSCTECSANFESRGRLNGHLRTAHGSVISCEMCGREFATEATYNLHMKTHLIIEREVHVCNNCGLLSEYNDRMLAHVADEDSGCFGMDVVVELMRDAYVCEYCSAYFKQKSDLSAHRASGVHKDGEFYCQPCRKKFTDMKLYRHHLRNYQQLRTDFSHRRLEICLHYMCDYENCSEAYINWNSLYTHKRRTHDAVEKQEPKIKNSEWICQFCQKVCRSKMSLSVHVARSHNNNNVVCSLCKASYKDEEALKKHHAYWHERIECPMCLKVVKNRRNYDTHIKVVHSNNKRYSCSECQKGFYHKSEMEAHQRLHSQSFKCEQCNFTTRNKKSLAVHVLGQHYKRFAFKCKFCDKRFGRRQGLSNHVLRVHSSKYTCRDFFDGGCGKSFGSTARLNVHVRKVHNSSLILSDDPAKLEDNEEEEEEEEVQAFEGPSTSNANTEIEFIADDDNENLTDSEIIEEIPERKPVTRQPRKTKPKPMTTRA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00496807;
90% Identity: iTF_00522388; iTF_00548997;
80% Identity: -