Basic Information

Insect: Drosophila ochracea
Gene Symbol: -
Assembly: GCA_035044125.1
Location: JAWNML010000046.1:2186870-2190740[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 7.7 4.8e+02 1.4 6.8 2 23 355 377 354 377 0.96

2 18 0.018 1.1 9.7 1.5 2 23 420 441 420 441 0.93

3 18 6 3.8e+02 1.8 2.9 2 17 452 467 451 478 0.79

4 18 4.5 2.8e+02 2.2 0.7 3 23 482 503 481 503 0.92

5 18 0.026 1.6 9.2 0.3 3 23 511 531 509 531 0.95

6 18 0.0037 0.23 11.9 0.2 1 23 539 562 539 562 0.98

7 18 3.5e-05 0.0022 18.2 0.2 2 23 567 588 566 588 0.97

8 18 9.4 5.9e+02 1.2 0.0 1 19 596 614 596 616 0.76

9 18 0.0011 0.069 13.5 0.3 1 22 636 657 636 660 0.91

10 18 0.058 3.6 8.1 2.8 3 21 667 685 667 686 0.93

11 18 0.013 0.85 10.1 0.6 1 23 705 730 705 730 0.96

12 18 0.012 0.77 10.2 1.4 2 23 746 768 745 768 0.93

13 18 0.0064 0.4 11.1 0.4 2 23 774 796 773 796 0.92

14 18 0.0025 0.16 12.4 0.2 2 23 800 822 799 822 0.96

15 18 1.4e-05 0.00087 19.5 2.2 1 23 828 850 828 850 0.98

16 18 0.0063 0.39 11.2 1.4 1 23 854 877 854 877 0.93

17 18 3e-05 0.0019 18.4 1.5 1 23 883 906 883 906 0.97

18 18 0.001 0.065 13.6 0.3 1 23 910 938 910 938 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	7.7	4.8e+02	1.4	6.8	2	23	355	377	354	377	0.96
2	18	0.018	1.1	9.7	1.5	2	23	420	441	420	441	0.93
3	18	6	3.8e+02	1.8	2.9	2	17	452	467	451	478	0.79
4	18	4.5	2.8e+02	2.2	0.7	3	23	482	503	481	503	0.92
5	18	0.026	1.6	9.2	0.3	3	23	511	531	509	531	0.95
6	18	0.0037	0.23	11.9	0.2	1	23	539	562	539	562	0.98
7	18	3.5e-05	0.0022	18.2	0.2	2	23	567	588	566	588	0.97
8	18	9.4	5.9e+02	1.2	0.0	1	19	596	614	596	616	0.76
9	18	0.0011	0.069	13.5	0.3	1	22	636	657	636	660	0.91
10	18	0.058	3.6	8.1	2.8	3	21	667	685	667	686	0.93
11	18	0.013	0.85	10.1	0.6	1	23	705	730	705	730	0.96
12	18	0.012	0.77	10.2	1.4	2	23	746	768	745	768	0.93
13	18	0.0064	0.4	11.1	0.4	2	23	774	796	773	796	0.92
14	18	0.0025	0.16	12.4	0.2	2	23	800	822	799	822	0.96
15	18	1.4e-05	0.00087	19.5	2.2	1	23	828	850	828	850	0.98
16	18	0.0063	0.39	11.2	1.4	1	23	854	877	854	877	0.93
17	18	3e-05	0.0019	18.4	1.5	1	23	883	906	883	906	0.97
18	18	0.001	0.065	13.6	0.3	1	23	910	938	910	938	0.89

Sequence Information

Coding Sequence: ATGTcggaaaatgtaaaaactgaCGAAAATGTGCCTAGCTGCCTGCATTGCAGAGTGTACAAttcgaaacaaaaatatcatgAGATATTCGACGAAGTCGGCATCGAAATAGAGCTGGCCAAACTGCTCGACAGGTATTTCGAGATAAAAGTTAAGCCCGCCGGCCAAAAACAGAAGCAACTGCTCTGCGAGGAGTGCGTTAATACGCTGATTCATTTCTTTGACATTGACGAACTGCAAAGGGAGCAAGATGCCGCAAATGGTGTAAATAAAAAGCCCAGTAATGATACAAAGTCTTCTGCTCCCAAAAAGGTTGAGAGTCCCGCGAAAAAGCAGACAGCTGCCGGCAAAAATGCACAAGGTAACGCCTCGGCGAATGCAGCCAAAAAGCAAGGGAAGccagcggcggctgctgctgcgattgctACGGCTGCTACTGGTCCAGAAGATAATACAAAAAGAGCGCCTGAAGCTATCGGCATACGCATCACCAGAGCCAGGAACGCTCCGCCAAAAAGATTGCCCATAAATATGAAGGAAGCAGTCAAGCGAAGTGGAACACTTAATAGCAAAGCAGACGTCAAACGGAGTCGGTCCAGAGAAGCTGCACAAGGATCAGGCGATCAGGAGCAGATTAGCGCACTCATACGTGACATTCTAGAAGATGAGGAGTCGCCAGCAGATGAAAAATTGGTagaagcagctgccacagtcCGTCAGCTGGAAAAACAATCAGCTGAAGAGCAACGGCAGCTGGAGGAGGCGGTGGAAGAGGAGCAAACGGTGCTCGAAGACCAAGACAATAATGATGAGCTAGAGTTTCTGGTTGAGCGTGAAGACAGCTCCTCGGAATTGAGCGTTCGCCATTTCAAATTGGAGCGAAAAATGAAACGCGTCTCGTCGCAGTCACAAAATGAGAGCCAAAGCGAGGATGAAGCATTCAAGGTGGAGCCCTTCAATTTTGTGCTGATCAAGGAATCTGATAATATTGGCGATCTGTACGAGTATTTGGGAACCGTGGTGAAGACCTGTTTTGAGACTTTGATCTTTGACTGGGACACTGTGTGCTGCCACTGCTCGCTGAAGTGCAGCAAATATGAAAGCTTATACGGTCACATGCTGAAGAGTCACAAAGAGCCGGACGATATTTACAAGTGCCCGATTGCTGACTGCGCGGCCGAGCTGCAGGGAGCCAAATCCTTGGCCATGCACCTGGTTGTGCTGCATGCGCCGGTAGCCGATATATCCATTTATGGCAGTTGTCCCGAATGCAACATTACCTTCTCAAACATATTGCAGTACAACAAGCACTCCTGCGCGCATGTCATCAAAAAGCGACGCGGCATCCGCCTGTATTGTGAGATGTGCGGCTTGGAGTTCCCCTCCTGGAAGCGCTTTAATTTCCacaatcaatttcatttggagCATCACAGGCCGCGCGCCTGTTTTGTGTGCGGCTACGCGGACACCAACATCGATGAGCTGTTCCATCATTTGCACTACGCCCACGAGCCAGAGGGCACGCTCTTCTGTGACCTCTGCGATCGCAATTTTCGGGATCCTGCCGTCTTTTTGGAGCACAACAAATCACACTCGAATGTCAGCAGCACCACCTACAGCTGCACCGAATGCAGCGCCAATTTTGAGTCACGTGGTCGTCTCAGTGGACACCTGCGCACCGCACATGGCAGCGTCATCAGCTGCGAAATGTGCGGCCGCGAGTTTGCCACGGAGGCCACATACAACCTGCACATGAAAACGCATCTGATTATTGAACGCGAGGTGCATGTGTGCAACAATTGTGGTCTGCTCAGTGAAAATAATGACAGGATGCTGgCCCATGTGGCGGAAGAGGATTCGGTTTGCTTTGGCATGGATGTGGTAGTGGAACTGATGCGTGATGCTTATGTCTGTGAGTTTTGCTCCGCGTACTTTAAGCAGAAGAGTGATTTAAGCGCCCATCGCGAATCGGGTGTGCACAAGGATGGCCACTTCTGGTGTCATCCGTGCGGCAAGAAGTTTACCGATATGAAGCTCTATCGTCACCATTTGCGCAACTATCAACAATTGCGCACAGATTTTTCGCATCGCCGTCTAGAAATTTGTCTCTACTATATGTGCGATTATGAGAATTGCAGTGAGGCCTATATTAATTGGAATTcgctatacacacacaagcggcGCACGCACGATGCCGTCGAGAAGCAGGAGCCTAAGACGAAGGATAACGAATGGATCTGTCAATTCTGTCAGAAAGTGTGCCGCTCCAAAATGTCGCTCTCGGTTCACGTGGCGCGCAGTCACAACAACAATAATGTGGTCTGCTCGCTCTGCAAGGCTTCGTATAAGGATGAGGAGGCGCTAAAGAAGCATCACGCCTATTGGCATGAGCGCATCGAGTGTCCGATGTGCTTAAAGGTGGTGAAGAATCGTCGCAACTTCGACACCCACATCAAGGTGGTGCACTCAAACAATAAACGTTACTCGTGCAGCGAATGCCAAAAAGGTTTCTATCACAAGAGCGAAATGGAGGCGCATCAGCGGCTGCATTCCCAATCGTTTAAATGCGAACAGTGCACCTTCACCACGAGGAACAAGAAATCGCTGTCGGTTCATGTGCTTGGCCAGCACTACAAGCGTTTTGCCTTCAAATGCAAGTATTGTGAGAAGCGCTTTGGACGCCGCCAGGGACTATCGAATCATATTCTACGTGTGCATGGCTCCAAATATACATGTCGTGACTTCTTCGATGGCGGTTGTGGCAAATCATTTGGCTCGCCGACACGCCTCAATGTGCATGTGCGAAAGACGCATAACAGCAGCCTTTTTGTGGCCGATGACCAAGCCAAATCGGAGGAAAACGAAGatgaggaggtggaggaggaggaggaggagccaGCTATGGTGGATTTGGCAAGCGAAGGTCCGTCTACGTCGAAGAAACGTTTAATTCGCATCAATGCGAACACTGAGATCGAATTCATTGGCGATGCAGCTGAAgccgacgacgacaacgagaGTCTGACTGATTCGGAACTGTGCGAAGAGCTTCAAGAGATCAAAGCAGTAGCAAAGCAGCCAcccaaaaagaaaccaaagcTAATGACAACGCGAGCATGA
Protein Sequence: MSENVKTDENVPSCLHCRVYNSKQKYHEIFDEVGIEIELAKLLDRYFEIKVKPAGQKQKQLLCEECVNTLIHFFDIDELQREQDAANGVNKKPSNDTKSSAPKKVESPAKKQTAAGKNAQGNASANAAKKQGKPAAAAAAIATAATGPEDNTKRAPEAIGIRITRARNAPPKRLPINMKEAVKRSGTLNSKADVKRSRSREAAQGSGDQEQISALIRDILEDEESPADEKLVEAAATVRQLEKQSAEEQRQLEEAVEEEQTVLEDQDNNDELEFLVEREDSSSELSVRHFKLERKMKRVSSQSQNESQSEDEAFKVEPFNFVLIKESDNIGDLYEYLGTVVKTCFETLIFDWDTVCCHCSLKCSKYESLYGHMLKSHKEPDDIYKCPIADCAAELQGAKSLAMHLVVLHAPVADISIYGSCPECNITFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLEHHRPRACFVCGYADTNIDELFHHLHYAHEPEGTLFCDLCDRNFRDPAVFLEHNKSHSNVSSTTYSCTECSANFESRGRLSGHLRTAHGSVISCEMCGREFATEATYNLHMKTHLIIEREVHVCNNCGLLSENNDRMLAHVAEEDSVCFGMDVVVELMRDAYVCEFCSAYFKQKSDLSAHRESGVHKDGHFWCHPCGKKFTDMKLYRHHLRNYQQLRTDFSHRRLEICLYYMCDYENCSEAYINWNSLYTHKRRTHDAVEKQEPKTKDNEWICQFCQKVCRSKMSLSVHVARSHNNNNVVCSLCKASYKDEEALKKHHAYWHERIECPMCLKVVKNRRNFDTHIKVVHSNNKRYSCSECQKGFYHKSEMEAHQRLHSQSFKCEQCTFTTRNKKSLSVHVLGQHYKRFAFKCKYCEKRFGRRQGLSNHILRVHGSKYTCRDFFDGGCGKSFGSPTRLNVHVRKTHNSSLFVADDQAKSEENEDEEVEEEEEEPAMVDLASEGPSTSKKRLIRINANTEIEFIGDAAEADDDNESLTDSELCEELQEIKAVAKQPPKKKPKLMTTRA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00496807;
90% Identity: iTF_00501963;
80% Identity: -