Basic Information

Insect: Drosophila demipolita
Gene Symbol: -
Assembly: GCA_035042405.1
Location: JAWNLI010000487.1:5641439-5645340[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.96 67 4.2 8.3 2 23 326 348 325 348 0.94

2 18 5.6 3.9e+02 1.8 0.0 1 23 355 380 355 380 0.91

3 18 0.044 3 8.4 1.8 2 23 391 412 391 412 0.93

4 18 5.3 3.7e+02 1.8 3.0 2 17 423 438 422 449 0.75

5 18 0.027 1.9 9.0 0.6 3 23 482 502 480 502 0.95

6 18 0.0037 0.26 11.8 0.4 1 23 510 533 510 533 0.98

7 18 5.6e-05 0.004 17.5 0.1 2 23 538 559 537 559 0.97

8 18 8.3 5.8e+02 1.2 0.0 1 19 567 585 567 587 0.76

9 18 3.7e-05 0.0026 18.1 0.5 1 23 607 631 607 631 0.91

10 18 0.63 44 4.7 3.5 3 21 638 656 638 657 0.93

11 18 0.0075 0.53 10.8 0.7 1 23 676 701 676 701 0.96

12 18 0.011 0.75 10.3 1.4 2 23 717 739 716 739 0.93

13 18 0.0065 0.45 11.0 0.3 2 23 745 767 744 767 0.92

14 18 0.0032 0.23 11.9 0.1 2 23 771 793 770 793 0.96

15 18 9.7e-05 0.0068 16.7 3.0 1 23 799 821 799 821 0.98

16 18 0.0021 0.15 12.5 1.3 1 23 825 848 825 848 0.93

17 18 0.0012 0.085 13.3 3.8 1 23 854 877 854 877 0.95

18 18 0.0044 0.31 11.5 0.2 1 23 881 909 881 909 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.96	67	4.2	8.3	2	23	326	348	325	348	0.94
2	18	5.6	3.9e+02	1.8	0.0	1	23	355	380	355	380	0.91
3	18	0.044	3	8.4	1.8	2	23	391	412	391	412	0.93
4	18	5.3	3.7e+02	1.8	3.0	2	17	423	438	422	449	0.75
5	18	0.027	1.9	9.0	0.6	3	23	482	502	480	502	0.95
6	18	0.0037	0.26	11.8	0.4	1	23	510	533	510	533	0.98
7	18	5.6e-05	0.004	17.5	0.1	2	23	538	559	537	559	0.97
8	18	8.3	5.8e+02	1.2	0.0	1	19	567	585	567	587	0.76
9	18	3.7e-05	0.0026	18.1	0.5	1	23	607	631	607	631	0.91
10	18	0.63	44	4.7	3.5	3	21	638	656	638	657	0.93
11	18	0.0075	0.53	10.8	0.7	1	23	676	701	676	701	0.96
12	18	0.011	0.75	10.3	1.4	2	23	717	739	716	739	0.93
13	18	0.0065	0.45	11.0	0.3	2	23	745	767	744	767	0.92
14	18	0.0032	0.23	11.9	0.1	2	23	771	793	770	793	0.96
15	18	9.7e-05	0.0068	16.7	3.0	1	23	799	821	799	821	0.98
16	18	0.0021	0.15	12.5	1.3	1	23	825	848	825	848	0.93
17	18	0.0012	0.085	13.3	3.8	1	23	854	877	854	877	0.95
18	18	0.0044	0.31	11.5	0.2	1	23	881	909	881	909	0.87

Sequence Information

Coding Sequence: ATGtcggaaaatataaaaactgacGAAAATGTGCCTAGCTGCCTGCATTGCAGAGTGtacaattcaaatcaaaaatatcatGAAATATTCGACGAAATCGGCATTGAAATAGAGCTCGCCAAACTGCTCGACAAGTATTTCGATATAAAAGTTGAGCCCGATGCccaaaagcagaagcagctgctCTGCGAGGAGTGCGTTAATACGCTGATTCGTTTCTTTGACATTGACGAACTTCGAAGGGAACAAGatgctgcaaatgctgcaaagAAAAATCCCGGTAATACAAAGTCTTCTACAAAATCCCCCAAAAACGATGAAATTCCCGCCAAAAAGCAGACAGCTGCCGTCAAAAATGGCCATGGTTCCCGAAACAAGCAAGAAAAGCCAACGGTAGCTGCAACGACTCATACTGCACATGATGTTATTGCAACAGGAGCGCCAGAAGCCGTCGGCAAGCGAAGTGAAACATCTAATGGCAATGCAGGCGTCAAACGGCGTCGGTCCAGAGAATCTGCTCAAGGATCAGGAGATCAGGAGCAGATTAGCGCACTCATTCGTGACATTCTAGAAGATGAGGAGTCTCCAGCCGATGAAAAGTTggtagaagcagcagcaacagtctgTCAACTGGAGAAAGAATCAGCTGTAGAGCAACTGCACCTGGATGAGGCGGTGGAGGCAGAGGAACTAGCGGAGCTCGAGGACCAGGACAATAATGAAGAGCTGGAGTTTCTGGTTGAGCGTGAAGATAGCTCCTCGGAATTGAGCGTGCGCCACTTCAAAGTGGAGCGAAAAGTTAAACGCGCCCCATCGCAGTCACAAAATGAGAGCCAAAGCGAAGACGAGGCATTCAAAGTGGAGCCCTTTAATTTTGTGCTAATCAAGGAATCTGATAACATTGGCGATCTATACGAGTATTTGGGAACCGTGGTGAAGACTTGTTTTGAGACTTTAACCTTTGACTGGGACACAATGTGCCGCCACTGCTCGCTGAAGTGcagcaaatatgaaaatttattccATCACATGCTGCAGCGTCACAAGGACCCAGGCGAGATTTACAAGTGCCCCATTAGTGAGTGTACCGTAGAAGTGCAGGGAGCCAAGGCCTTGGCCATGCACCTAATTGTGCTGCATGCGCCAGTAGCCGATATTCCCATTTATGGCAGCTGTCCCGAATGCAGCATGACCTTCTCAAATATATTGCAGTACAACAAACACTCCTGCGCGCATGTCATCAAAAAGCGTCGCGGCATACGCTTGTATTGTGAGATGTGCGGCTTGGAGTTCCCCTCCTGGAAGCGCTTTAATTTTCacaatcaatttcatttggaGCGTCACAGGCCGCGCGCCTGTTTTGTGTGCAGCTACGAGGATACCAACATAGATGAGCTTTTCCATCATTTGCACTACTCTCACGAGCCAGAGGGCACGCTCTTCTGTGATCTCTGTGATCGCAATTTTCGAGATCCTACAGTCTTTTTGGAGCACAACAAATCACACTCAAATGTCAGCAGCACCACTTACAGCTGCACCGAATGCAGCTCCAATTTTGAGTCACGTGGTCGTCTCAATGGACATCTGCGCACCGCACATGGCAGCGTCATTAGCTGCGAAATGTGCGGCCGCGAGTTTGGCACGGAGGCCACCTACAACGTGCACATGAAGACACATCTGATTATTGAGCGCGAGGTTCATGTGTGCAACAATTGCGGACTGCTTAGCGAAAATAATGATAGGATGCTGGCTCATGTGGCCGATGAGGATTCGGGTTGCTTTGGCATGGATGTGGTAGCGGAACTGATGCGTGATGCATACGTTTGTGAATATTGCTCGGCCTACTTTAAGCAAAAAAGCGATTTAAGAGCCCATCGCAATTCGGGGGTCCATAAGGATGGCCACTTTTGGTGTCATCCTTGCTCCAAGAAATTTACCGATATGAAGCTCTACCGCCACCACCTGCGCAACTATCAACAACTGCGCACAGATTTTGCGCATCGCCGTCTGGAAATTTGTCTCTACTATATGTGCGATAATGAGAAATGCAGTGAAGCCTATATTAATTGGAATTcgctatacacacacaaacggcGCACACACGATGCCGCCGAGAAGCAAGAGCCCAAGTTTAAAGATAACGAGTGGATATGTCAGTTCTGTCAGAAAGTGTGCCGCTCCAAAATGTCGCTCTCGGTTCACGTGGCGCGCAGTCACAACAACAATAATGTGCCCTGCTCGCTGTGCAAAGCTTCGTATAAGGATGAGGAGGCGCTAAAAAAGCATCACGCCTATTGGCATGAGCGCATCGAGTGTCCGATGTGCTTGAAGGTTGTGAAAAATCGACGCAACTATGACACCCACATAAAGGTGGTGCACTCAAACAACAAGCGTTACACGTGCAGTGAATGCCAAAAAGGTTTCTACCACAAGAGCGAAAAGGAGGCGCATCAGCGGCTGCATTCTCAATCGTTTAAATGCGAACAGTGCAACTTCACCACGAGGAACAAGAAATCGCTGTCGGTTCATGTGCTGGGTCAGCATTACAAGCGTTTTGCCTTCAAGTGTAAGTTCTGTGACAAGCGTTTTGGACGCCGCCAGGGACTATCGAATCATACTCTACATGTGCATGGCTCGAAATTTACATGTCGTGACTTTTTTGAAGGCGGTTGTGGCAAATCATTTGGATCGACGGCACGGCTCAACGTGCATGTGCGAAAGGTGCATTATGGCAGCCAGTTTCTGGCCGATGACCCTGCCAAATTAGAGGAAAAGGAGCAAGCGGAGGAGGATGAGCCGGCAAGCGATGGTCCGTCCACATCGAAGAAACGTTTAATTCGCATTGGTGCGAACACTGAAATTGAGTTCATTGGCGATGCAGCAGATGCCGATGACGACATTGAGAGCCTGACTGATTCCGAAATCTTCGAAGAGTGTCAGGAAGTGAAAGCAGTAGCAAAGCAGCCACCAAAGAAGAAACCAAAACCAATGACAACGAGAGCCTGA
Protein Sequence: MSENIKTDENVPSCLHCRVYNSNQKYHEIFDEIGIEIELAKLLDKYFDIKVEPDAQKQKQLLCEECVNTLIRFFDIDELRREQDAANAAKKNPGNTKSSTKSPKNDEIPAKKQTAAVKNGHGSRNKQEKPTVAATTHTAHDVIATGAPEAVGKRSETSNGNAGVKRRRSRESAQGSGDQEQISALIRDILEDEESPADEKLVEAAATVCQLEKESAVEQLHLDEAVEAEELAELEDQDNNEELEFLVEREDSSSELSVRHFKVERKVKRAPSQSQNESQSEDEAFKVEPFNFVLIKESDNIGDLYEYLGTVVKTCFETLTFDWDTMCRHCSLKCSKYENLFHHMLQRHKDPGEIYKCPISECTVEVQGAKALAMHLIVLHAPVADIPIYGSCPECSMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCSYEDTNIDELFHHLHYSHEPEGTLFCDLCDRNFRDPTVFLEHNKSHSNVSSTTYSCTECSSNFESRGRLNGHLRTAHGSVISCEMCGREFGTEATYNVHMKTHLIIEREVHVCNNCGLLSENNDRMLAHVADEDSGCFGMDVVAELMRDAYVCEYCSAYFKQKSDLRAHRNSGVHKDGHFWCHPCSKKFTDMKLYRHHLRNYQQLRTDFAHRRLEICLYYMCDNEKCSEAYINWNSLYTHKRRTHDAAEKQEPKFKDNEWICQFCQKVCRSKMSLSVHVARSHNNNNVPCSLCKASYKDEEALKKHHAYWHERIECPMCLKVVKNRRNYDTHIKVVHSNNKRYTCSECQKGFYHKSEKEAHQRLHSQSFKCEQCNFTTRNKKSLSVHVLGQHYKRFAFKCKFCDKRFGRRQGLSNHTLHVHGSKFTCRDFFEGGCGKSFGSTARLNVHVRKVHYGSQFLADDPAKLEEKEQAEEDEPASDGPSTSKKRLIRIGANTEIEFIGDAADADDDIESLTDSEIFEECQEVKAVAKQPPKKKPKPMTTRA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00496807;
90% Identity: iTF_00543918;
80% Identity: -