Basic Information

Insect: Drosophila melanocephala
Gene Symbol: -
Assembly: GCA_037043625.1
Location: JBAMBD010000018.1:2194392-2198505[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.1 75 4.0 5.3 2 23 357 379 356 379 0.96

2 15 0.018 1.2 9.7 1.8 2 23 422 443 422 443 0.93

3 15 5.6 3.7e+02 1.8 3.0 2 17 454 469 453 480 0.75

4 15 3.3e-05 0.0022 18.3 0.2 2 23 541 562 540 562 0.97

5 15 8.8 5.8e+02 1.2 0.0 1 19 570 588 570 590 0.76

6 15 0.001 0.068 13.6 0.3 1 22 610 631 610 634 0.91

7 15 1.7 1.1e+02 3.4 2.6 3 21 641 659 641 660 0.93

8 15 0.013 0.83 10.2 0.6 1 23 679 704 679 704 0.96

9 15 0.011 0.75 10.3 1.4 2 23 720 742 719 742 0.93

10 15 0.006 0.39 11.2 0.4 2 23 748 770 747 770 0.92

11 15 0.0023 0.15 12.5 0.2 2 23 774 796 773 796 0.96

12 15 1.3e-05 0.00085 19.6 2.2 1 23 802 824 802 824 0.98

13 15 0.0016 0.1 13.0 1.2 1 23 828 851 828 851 0.93

14 15 0.00014 0.0092 16.3 1.6 1 23 857 880 857 880 0.97

15 15 0.0037 0.25 11.8 0.2 1 23 884 912 884 912 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.1	75	4.0	5.3	2	23	357	379	356	379	0.96
2	15	0.018	1.2	9.7	1.8	2	23	422	443	422	443	0.93
3	15	5.6	3.7e+02	1.8	3.0	2	17	454	469	453	480	0.75
4	15	3.3e-05	0.0022	18.3	0.2	2	23	541	562	540	562	0.97
5	15	8.8	5.8e+02	1.2	0.0	1	19	570	588	570	590	0.76
6	15	0.001	0.068	13.6	0.3	1	22	610	631	610	634	0.91
7	15	1.7	1.1e+02	3.4	2.6	3	21	641	659	641	660	0.93
8	15	0.013	0.83	10.2	0.6	1	23	679	704	679	704	0.96
9	15	0.011	0.75	10.3	1.4	2	23	720	742	719	742	0.93
10	15	0.006	0.39	11.2	0.4	2	23	748	770	747	770	0.92
11	15	0.0023	0.15	12.5	0.2	2	23	774	796	773	796	0.96
12	15	1.3e-05	0.00085	19.6	2.2	1	23	802	824	802	824	0.98
13	15	0.0016	0.1	13.0	1.2	1	23	828	851	828	851	0.93
14	15	0.00014	0.0092	16.3	1.6	1	23	857	880	857	880	0.97
15	15	0.0037	0.25	11.8	0.2	1	23	884	912	884	912	0.89

Sequence Information

Coding Sequence: ATGTcggaaaatgtaaaaactgACGAAAATGTGCCTAGCTGCCTGCATTGCAGAGTGTACAATtcgaaacaaaaatatcatgAGATATTCGACGAAGTCGGCATCGAAATAGAGCTGGCCAAACTGCTCGACAGGTATTTCGAGATAAAAGTTGAGCCCGCCGGCCAAAAACAGAAGCAACTGCTCTGCGAGGAGTGCGTTAATACGCTGATTCGTTTCTTTGACATCGACGAACTGCAAAGGGAGCAAGATGCCGCAATTGGTGCAAATAAAAAGACCAGTAAGGATACAAAGTCTTCTGCTCCCAAAAAGGATGAGAGTCCCGCGAAAAAGCAGACAGCTGCCGAGAAAAATGCCCAAGGTTCATCAAACACCTCGGCGAATGCAACCATAAAGCAAGAGAAGCCaacggcggctgctgctgcaattgctacgactgctgctgctcctgatgATATTACAAAAGGAGCACCAGAAGCCGTCGGCATACGCATCACCAGAGCCAGGAACGCTCCGCCAAAAAGATTGCCCATAAATATGAAGAAAGCAGTCAAGCGAAGTGGAACACTTAATGGCAAAGTAGACGTCAAACGGAGTCGGTCCAGAGAAGCTGCACAAGGATCAGGCGATCAGGAGCAGATTAGCGCACTCATACGTGACATTCTAGAGGATGAGGAGTCGCCAGCGGATGAAAAATTGGTAgaagcagctgccacagtCCGTCAGCTGGAGAAACAATCAGCTGAAGAGCAACGGCAGCTGGAGGAGGCGGTGGAAGAGGAGCAAGCGGTGCTCGAGGACCAGGACAATAATGATGAGCTGGAGTTTCTGGTTGAGCGTGAAGATAGCTCCTCGGAATTGAGCGTGCGCCATTTCAAAGTGGAGCGAAAAGTGAAACGCGCCCGATCGCTGTCACAAAATGAGAGCCAAAGCGAGGATGAAGCATTCAAAGTGGAGCCCTTTAATTTTGTGCTGATCAAGGAAACTGATAATATTGGCGATCTGTACGAGTATTTGGGAACCGTGGTGAAGACCTGTTTTGAGACTTTGATCTTTGACTGGGACACTGTGTGCCGCCACTGCTCGCTGAAGTGCAGCAAATATGAAAGTTTATTCGGTCACATGCTGAAGCGTCACAAGGAGCCGGACGATATTTACAAGTGTCCGATTGTTGACTGCGCGACAGAGCTGCAGGGAGCCAAATCCTTGGCCATGCACCTGGTTGTGCTGCATGCCCCGGTAGCCGATATACCCATTTATGGCAGTTGTCCCGAATGCAACATGACCTTCTCAAACATATTGCAGTACAACAAGCACTCCTGCGCGCATGTCATCAAAAAGCGACGCGGCATACGCCTGTATTGTGAGATGTGCGGCTTGGAGTTCCCCTCCTGGAAGCGCTTTAATTTTcacaatcaatttcatttggagCGTCACAGGCCGCGCGCCTGTTTTGTGTGCAGCTACGCGGATACCAACATCGATGAGCTGTTCCACCATTTGCACTACGCTCACGAGCCAGAGGCACGCTCTTCAGACCTCTGTGATCGCAATTTTCGGGATCCTGCCTCACGTGGTCGTCTCAATGGACACCTGCGCACCGCACATGGCAGCGTCATCAGCTGCGAAATGTGCGGCCGCGAGTTTGCCACGGAGGCCACATACAACCTGCACATGAAAACGCATCTGATTATTGAACGCGAGGTGCATGTGTGCAACAATTGTGGTCTGCTCAGTGAAAATAATGACAGGATGCTGGCTCATGTGGCGGAAGAGGATTCGAGTTGCTTTGCCATGGATGTGGTAGTGGAACTGATGCGTGATGCTTATGTTTGTGAATTTTGCTCCGCCTACTTTAAGCAGAAGAGTGACTTAAGCGCCCATCGCGAATCGGGGGTGCACAAGGATGGCCACTTCTGGTGTCATCCTTGCGCCAAGAAGTTCACTGATATGAAGCTCTACCGTCACCATTTGCGCAACTATCAACAATTGCGCACAGATTTTTCGCATCGCCGGCTAGAAATTTGTCTCTACTACATGTGCGACTATGAGAATTGCAGTGAGGCCTATATTAATTGGAATTcgctatacacacacaaacggcGCACGCACGATGCCGTCGAGAAGCAGGAGCCCAAGACGAAAGATAACGAATGGATCTGTCAATTCTGTCAGAAAGTGTGCCGCTCCAAAATGTCGCTCTCGGTTCACGTGGCgcgcagccacaacaacaATAATGTGGTCTGCTCGCTCTGCAAAGCTTCGTATAAGGATGAGGAGGCGCTAAAGAAGCATCACGCCTATTGGCATGAGCGCATAGAGTGTCCGATGTGCTTGAAGGTGGTGAAGAATCGTCGCAACTTCGACACCCACATAAAGGTGGTGCACTCAAACAATAAGCGTTACTCGTGCAGTGAATGCCAAAAAGGTTTCTATCACAAGAGCGAAATGGAGGCGCATCAGCGGCTGCATTCCCAATCGTACAAATGCGAACAGTGCAACTTCACCACGAGGAACAAGAAATCGCTGTCGGTTCATGTGCTGGGTCAGCACTACAAGCGTTTTGCCTTCAAGTGTAAGTTCTGTGAGAAGCGCTTTGGACGCCGCCAGGGATTATCGAATCATATTCTACGTGTGCATGGCTCGAAATATACATGTCGTGACTTCTTCGATGGCGGTTGTGGCAAATCATTTGGCTCGACGGCACGCCTCAACGTGCATGTGCGAAAGGCGCATAACAGCAGCCTCTTTCTGACCGATGACCCAGCCAAATCGGAGGAAAACGaagatgaggaggaggaggaggagccgGCTACGGTGGATTCGGCAAGCGAAGGTCCGTCCACATCGAAGAAACGTTTAATTCGCATCAATGCGAACACCGAGATTGAATTCATTGGCGATGCAGCTGATGCCGAGGACGACAACGAGAGTCTTCCTGATTCGGAAATCTTCGAAGAGTTTGAAGAGATCAAAGCAGTAACAAAACAGCcaccaaaaaagaaacgaaagcCAATGACAACGAGAGCATGA
Protein Sequence: MSENVKTDENVPSCLHCRVYNSKQKYHEIFDEVGIEIELAKLLDRYFEIKVEPAGQKQKQLLCEECVNTLIRFFDIDELQREQDAAIGANKKTSKDTKSSAPKKDESPAKKQTAAEKNAQGSSNTSANATIKQEKPTAAAAAIATTAAAPDDITKGAPEAVGIRITRARNAPPKRLPINMKKAVKRSGTLNGKVDVKRSRSREAAQGSGDQEQISALIRDILEDEESPADEKLVEAAATVRQLEKQSAEEQRQLEEAVEEEQAVLEDQDNNDELEFLVEREDSSSELSVRHFKVERKVKRARSLSQNESQSEDEAFKVEPFNFVLIKETDNIGDLYEYLGTVVKTCFETLIFDWDTVCRHCSLKCSKYESLFGHMLKRHKEPDDIYKCPIVDCATELQGAKSLAMHLVVLHAPVADIPIYGSCPECNMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCSYADTNIDELFHHLHYAHEPEARSSDLCDRNFRDPASRGRLNGHLRTAHGSVISCEMCGREFATEATYNLHMKTHLIIEREVHVCNNCGLLSENNDRMLAHVAEEDSSCFAMDVVVELMRDAYVCEFCSAYFKQKSDLSAHRESGVHKDGHFWCHPCAKKFTDMKLYRHHLRNYQQLRTDFSHRRLEICLYYMCDYENCSEAYINWNSLYTHKRRTHDAVEKQEPKTKDNEWICQFCQKVCRSKMSLSVHVARSHNNNNVVCSLCKASYKDEEALKKHHAYWHERIECPMCLKVVKNRRNFDTHIKVVHSNNKRYSCSECQKGFYHKSEMEAHQRLHSQSYKCEQCNFTTRNKKSLSVHVLGQHYKRFAFKCKFCEKRFGRRQGLSNHILRVHGSKYTCRDFFDGGCGKSFGSTARLNVHVRKAHNSSLFLTDDPAKSEENEDEEEEEEPATVDSASEGPSTSKKRLIRINANTEIEFIGDAADAEDDNESLPDSEIFEEFEEIKAVTKQPPKKKRKPMTTRA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00496807;
90% Identity: iTF_00501963;
80% Identity: -