Basic Information

Insect: Drosophila picticornis
Gene Symbol: -
Assembly: GCA_035043845.1
Location: JAWNMR010000493.1:17530565-17534658[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.2 76 4.0 5.3 2 23 356 378 355 378 0.96

2 17 0.019 1.2 9.6 1.8 2 23 421 442 421 442 0.93

3 17 5.9 3.6e+02 1.8 3.0 2 17 453 468 452 479 0.75

4 17 0.026 1.6 9.2 0.3 3 23 512 532 510 532 0.95

5 17 0.0014 0.089 13.2 0.2 1 23 540 563 540 563 0.98

6 17 3.5e-05 0.0022 18.3 0.2 2 23 568 589 567 589 0.97

7 17 9.4 5.8e+02 1.2 0.0 1 19 597 615 597 617 0.76

8 17 0.0046 0.29 11.6 0.2 1 22 637 658 637 661 0.90

9 17 0.058 3.6 8.1 2.8 3 21 668 686 668 687 0.93

10 17 0.014 0.84 10.1 0.6 1 23 706 731 706 731 0.96

11 17 0.012 0.76 10.3 1.4 2 23 747 769 746 769 0.93

12 17 0.0064 0.4 11.1 0.4 2 23 775 797 774 797 0.92

13 17 0.0019 0.11 12.8 0.3 2 23 801 823 800 823 0.96

14 17 1.4e-05 0.00086 19.5 2.2 1 23 829 851 829 851 0.98

15 17 0.0024 0.15 12.5 1.3 1 23 855 878 855 878 0.93

16 17 8.7e-05 0.0054 17.0 1.1 1 23 884 907 884 907 0.97

17 17 0.0049 0.3 11.5 0.2 1 23 911 939 911 939 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.2	76	4.0	5.3	2	23	356	378	355	378	0.96
2	17	0.019	1.2	9.6	1.8	2	23	421	442	421	442	0.93
3	17	5.9	3.6e+02	1.8	3.0	2	17	453	468	452	479	0.75
4	17	0.026	1.6	9.2	0.3	3	23	512	532	510	532	0.95
5	17	0.0014	0.089	13.2	0.2	1	23	540	563	540	563	0.98
6	17	3.5e-05	0.0022	18.3	0.2	2	23	568	589	567	589	0.97
7	17	9.4	5.8e+02	1.2	0.0	1	19	597	615	597	617	0.76
8	17	0.0046	0.29	11.6	0.2	1	22	637	658	637	661	0.90
9	17	0.058	3.6	8.1	2.8	3	21	668	686	668	687	0.93
10	17	0.014	0.84	10.1	0.6	1	23	706	731	706	731	0.96
11	17	0.012	0.76	10.3	1.4	2	23	747	769	746	769	0.93
12	17	0.0064	0.4	11.1	0.4	2	23	775	797	774	797	0.92
13	17	0.0019	0.11	12.8	0.3	2	23	801	823	800	823	0.96
14	17	1.4e-05	0.00086	19.5	2.2	1	23	829	851	829	851	0.98
15	17	0.0024	0.15	12.5	1.3	1	23	855	878	855	878	0.93
16	17	8.7e-05	0.0054	17.0	1.1	1	23	884	907	884	907	0.97
17	17	0.0049	0.3	11.5	0.2	1	23	911	939	911	939	0.87

Sequence Information

Coding Sequence: ATGTcggaaaatgtaaaaactgACGAAAATGTGCCTAGCTGCCTGCATTGCAGAGTGTACAATTCGAAACAGAAATATCATGAGATATTCGACGAAGTCGGCATCGAAATAGAGCTCGCCAAGCTGCTCGACAGGTATTTCGAGATAAAAGTTGAGCCCGCCGGCcagaaacagaagcaactGCTCTGCGAGGAGTGCGTTAATACGCTAATTCGTTTCTTTGACATCGACGAACTGCAAAGGGAGCAAGATGCCGCAAATGGTGCAAATAAAAAGCCCAGTAATGATACAAAGTCTCCCGCTCCCAAAAAGGATGAGAGCCCCGCGAAAAGGCAGACAGCTGCCGACAAAAATGCCCAAGGTTCATCAAACACCTCGGCGAAAGCAGGCAAAAAGCAAGAGAAGCCAACGACGGCTGCTGCGATTGctacgactgctgctgctcccgaTGATATTACAAAAGCAGCGCCAGAAGCCGTCGGCATACGCATCACCAGAGCCAGGAATGCTCCGCCAAAAAGATTGCCCATAAATATGAAGAAAGCAGTCAAGCGAAGTGGAACACTTAATGGCAAAGCAGACGTCAAACGGAATCGGTCCAGAGAAGCTGCACAAGGATCAGGCGATCAGGAGCAGATTAGCGCACTCATCCGTGACATTCTAGAGGATGAGGAGTCGCCAGCCGATGAAAAACTGGTAGAAGCAGCGGCCACAGTCCGTCAGCTGGAAAAACAATCAGCTGAAGAGCAACGGCATCTGGAAGGGGCGGTGGAAGAGGAGCAAGTGGTGCTCGAGGACCAGGACAATAACGATGAGCTGGAGTTTCTGGTTGAGCGAGAAGACAGCTCCTCGGAATTGAGTGTGCGCCATTTCAAAGTGGAGCGAAAAATGAAACGAGCCCCTTCGCAGTCACAAAATGAGAGCCAAAGCGAGAATGAAGCATTCAAAGTGGAGCCCTTTAATTTTGTGCTGATCAAGGAATCTGACAACATTGGCGATCTGTACGAGTATTTGGGAACCGTGGTGAAGACCTGTTTTGAGACTTTGAACTTTGACTGGGACACTGTGTGCCGCCACTGCTCGCTGAAGTGCAGCAAATATGAAAGTTTATTCGGTCACATGCTGAAGCGTCACAAGGAGCCGGGCGATATTTACAAGTGCCCGATTGCAGACTGCGCGACCGAGCTGCAGGGAGCCAAATCCTTAGCCATGCACCTGGTTGTGCTGCATGCGCCGGTAGCCGATATACCCATTTATGGCAGTTGTCCCGAATGCAACATGACCTTCTCAAACATATTGCAGTACAACAAGCACTCCTGCGCGCATGTCATCAAAAAGCGACGCGGCATACGCCTGTATTGTGAGATGTGCGGCTTGGAGTTCCCCTCCTGGAAGCGctttaattttcacaatcaatttcatttggagCGTCACAGGCCGCGAGCCTGCTTTGTGTGCAGCTATGCGGACACCAACATCGATGAGCTGTTCCATCATTTGCACTACGCTCACGAGCCAGAGGGCACGCTCTTCTGTGACCTCTGTGATCGCAATTTTCGGGATCCTGCCGTCTTTTTGGAGCACAACAAATCACACTCGAATGTCAGCAGCACCACCTACAGCTGCACAGAATGCAGCGCCAATTTTGAGTCACGTGGTCGTCTCAATGGACACCTGCGCACCGCACATGGCAGCGTCATCAGCTGCGAAATGTGCGGCCGCGAGTTTGCCACGGAGGCCACATACAATCTGCACATGAAAACGCATCTGATTATTGAACGCGAGGTGCATGTGTGCAACAATTGTGGTCTGCTCAGTGAGAATAATGACAGGATGCTGGCTCATGTGGCGGAAGAGGATTCGGCTTGCTTTGGCATGGATGTGGCAGTGGAACTAATGCGTGATGCTTATGTCTGTGAATTTTGCTCCGCCTACTTTAAGCAGAAGAGTGATTTAGGCGCCCATCGCGAATCGGGGGTGCACAAGGATGGCCACTTCTGGTGTCATCCGTGCGGCAAGAAGTTCACCGATATGAAGCTCTATCGTCACCACTTGCGCAACTATCAACAATTGCGCACAGATTTTTCGCATCGCCGGCTAGAAATTTGTCTCTACTACATGTGCGATTATGAGAATTGCAGTGAGGCCTATATTAATTGGAATTcgctatacacacacaagcggcGCACACACGATGCCGTCGAGAAGCAGGAGCCCAAGACGAAGGATAACGAATGGATCTGTCAATTCTGTCAGAAAGTGTGCCGCTCCAAAATGTCGCTCTCGGTTCACGTGGCGCGCAGTCACAATAACAATAATGTTGTCTGCTCGCTCTGCAAGGCTTCGTATAAGGATGAGGAGGCGCTAAAGAAGCATCACGCCTATTGGCATGAGCTCATAGAGTGTCCGAAGTGCTTGAAGGTGGTGAAGAATCGTCGCAACTTCGACACCCACATCAAAGTGGTGCACTCAAACAATAAGCGTTACTCGTGCAGTGAATGCCAAAAAGGTTTCTATCACAAGAGCGAAATGGAGGCCCATCAGCGGCTGCATTCGCAATCGTTTAAATGCGAACAGTGCAACTTCACCACGAGGAACAAGAAGTCGCTGTCGGTTCATGTGCTGGGTCAGCACTACAAGCGTTTTGCCTTCAAGTGTAAGTTGTGTGAGAAGCGCTTTGGACGCCGCCAGGGCCTATCGAATCATATTCTACGTGTGCATGGCTCTAAATTTACGTGTCGTGACTTCTTCGATGGCGGTTGTGGCAAATCATTTGGGTCGACGGCACGCCTCAATGTGCACGTGCGAAAGGCGCATAACAGCAGCCTCTTTCTGACTGATGACCCAGCCAAATCGGAGGAAAACGAAGATGaagaggaggtggaggaggagccGGCTATGGTGGATTCGGCAAACGAAGGACCGTCCACATCGAAGAAACGTTTAATTCGCATCAATGCAAACactgaaattgaattcattggCGATGCAGCTGATCCGGAGGATGACGACGAGAGTGTGACGGATTCGGAAATCTACGAAGAGTTTGAAGAGGTCAAAGCAGTAGCAAAGCAGCcaccaaaaaagaaaccaaagccAATGACAACGCGAGCATGA
Protein Sequence: MSENVKTDENVPSCLHCRVYNSKQKYHEIFDEVGIEIELAKLLDRYFEIKVEPAGQKQKQLLCEECVNTLIRFFDIDELQREQDAANGANKKPSNDTKSPAPKKDESPAKRQTAADKNAQGSSNTSAKAGKKQEKPTTAAAIATTAAAPDDITKAAPEAVGIRITRARNAPPKRLPINMKKAVKRSGTLNGKADVKRNRSREAAQGSGDQEQISALIRDILEDEESPADEKLVEAAATVRQLEKQSAEEQRHLEGAVEEEQVVLEDQDNNDELEFLVEREDSSSELSVRHFKVERKMKRAPSQSQNESQSENEAFKVEPFNFVLIKESDNIGDLYEYLGTVVKTCFETLNFDWDTVCRHCSLKCSKYESLFGHMLKRHKEPGDIYKCPIADCATELQGAKSLAMHLVVLHAPVADIPIYGSCPECNMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCSYADTNIDELFHHLHYAHEPEGTLFCDLCDRNFRDPAVFLEHNKSHSNVSSTTYSCTECSANFESRGRLNGHLRTAHGSVISCEMCGREFATEATYNLHMKTHLIIEREVHVCNNCGLLSENNDRMLAHVAEEDSACFGMDVAVELMRDAYVCEFCSAYFKQKSDLGAHRESGVHKDGHFWCHPCGKKFTDMKLYRHHLRNYQQLRTDFSHRRLEICLYYMCDYENCSEAYINWNSLYTHKRRTHDAVEKQEPKTKDNEWICQFCQKVCRSKMSLSVHVARSHNNNNVVCSLCKASYKDEEALKKHHAYWHELIECPKCLKVVKNRRNFDTHIKVVHSNNKRYSCSECQKGFYHKSEMEAHQRLHSQSFKCEQCNFTTRNKKSLSVHVLGQHYKRFAFKCKLCEKRFGRRQGLSNHILRVHGSKFTCRDFFDGGCGKSFGSTARLNVHVRKAHNSSLFLTDDPAKSEENEDEEEVEEEPAMVDSANEGPSTSKKRLIRINANTEIEFIGDAADPEDDDESVTDSEIYEEFEEVKAVAKQPPKKKPKPMTTRA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00496807;
90% Identity: iTF_00501963;
80% Identity: -