Basic Information

Insect: Drosophila cyrtoloma
Gene Symbol: -
Assembly: GCA_035042485.1
Location: JAWNLH010000672.1:2136158-2140296[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.2 78 4.0 5.3 2 23 357 379 356 379 0.96

2 17 0.019 1.2 9.6 1.8 2 23 422 443 422 443 0.93

3 17 5.7 3.7e+02 1.8 3.0 2 17 454 469 453 480 0.75

4 17 0.026 1.7 9.2 0.3 3 23 513 533 511 533 0.95

5 17 0.0014 0.092 13.2 0.2 1 23 541 564 541 564 0.98

6 17 3.4e-05 0.0022 18.2 0.2 2 23 569 590 568 590 0.97

7 17 9.2 6e+02 1.2 0.0 1 19 598 616 598 618 0.76

8 17 0.0011 0.071 13.5 0.3 1 22 638 659 638 662 0.91

9 17 0.69 45 4.7 3.5 3 21 669 687 669 688 0.93

10 17 0.013 0.86 10.1 0.6 1 23 707 732 707 732 0.96

11 17 0.012 0.78 10.2 1.4 2 23 748 770 747 770 0.93

12 17 0.0063 0.41 11.1 0.4 2 23 776 798 775 798 0.92

13 17 0.0024 0.16 12.4 0.2 2 23 802 824 801 824 0.96

14 17 1.4e-05 0.00088 19.5 2.2 1 23 830 852 830 852 0.98

15 17 0.0023 0.15 12.5 1.3 1 23 856 879 856 879 0.93

16 17 0.00015 0.0095 16.3 1.6 1 23 885 908 885 908 0.97

17 17 0.0039 0.26 11.8 0.2 1 23 912 940 912 940 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.2	78	4.0	5.3	2	23	357	379	356	379	0.96
2	17	0.019	1.2	9.6	1.8	2	23	422	443	422	443	0.93
3	17	5.7	3.7e+02	1.8	3.0	2	17	454	469	453	480	0.75
4	17	0.026	1.7	9.2	0.3	3	23	513	533	511	533	0.95
5	17	0.0014	0.092	13.2	0.2	1	23	541	564	541	564	0.98
6	17	3.4e-05	0.0022	18.2	0.2	2	23	569	590	568	590	0.97
7	17	9.2	6e+02	1.2	0.0	1	19	598	616	598	618	0.76
8	17	0.0011	0.071	13.5	0.3	1	22	638	659	638	662	0.91
9	17	0.69	45	4.7	3.5	3	21	669	687	669	688	0.93
10	17	0.013	0.86	10.1	0.6	1	23	707	732	707	732	0.96
11	17	0.012	0.78	10.2	1.4	2	23	748	770	747	770	0.93
12	17	0.0063	0.41	11.1	0.4	2	23	776	798	775	798	0.92
13	17	0.0024	0.16	12.4	0.2	2	23	802	824	801	824	0.96
14	17	1.4e-05	0.00088	19.5	2.2	1	23	830	852	830	852	0.98
15	17	0.0023	0.15	12.5	1.3	1	23	856	879	856	879	0.93
16	17	0.00015	0.0095	16.3	1.6	1	23	885	908	885	908	0.97
17	17	0.0039	0.26	11.8	0.2	1	23	912	940	912	940	0.89

Sequence Information

Coding Sequence: ATGTcggaaaatgtaaaaactgACGAAAATGTGCCTAGCTGCCTGCATTGCAGAGTGTACAATtcgaaacaaaaatatcatgAGATATTCGACGAAGTCGGCATCGAAATAGAGCTGGCCAAACTGCTCGACAGGTATTTCGAGGTAAAAGTTGAGCCCGCCGGCCAAAAACAGAAGCAACTGCTCTGCGAGGAGTGCGTTAATACGCTGATTCGTTTCTTTGACATCGACGAACTGCAAAGGGAGCAAGATGCCGCAAATGGTGCAAATAAAAAGCCCAGTAATGATACAAAGTCTTCTGCTCTCAAAAAGGATGAGAGTCCCGCGAAAAAGCAGACAGCTGCCGAGAAAAATGCCCAAGGTTCACCAAACACCTCGGCGAATGCAGCCATAAAGCAAGAGAAGCCaacggcggctgctgctgcaattgctacgactgctgctgctcctgatgATATTAAAAAAGGAGCGCCAGAAGCCGTCGGCATACGCATCACCAGAGCCAGGAACGCTCCGCCAAAAAGATTGCCCATAAATATGAAGAAAGCAGTCAAGCGAAGTGGAACACTTAATGGCAAAGTAGACGTCAAACGGAGTCGGTCCAGAGAAGCTGCACAAGGATCAGGCGATCAGGAGCAGATTAGCGCACTCATACGTGACATTCTAGAGGATGAGGAGTCGCCAGCGGATGAAAAATTGGTagaagcagctgccacagtCCGTCAGCTGGAGAAACAATCAGCTGAAGAGCAACGGCAGCTGGAGGAGGCGGTGGAAGAGGAGCAAGCGGTGCTCGAGGACCAGGACAATAATGATGAGCTGGAGTTTCTGGTTGAGCGTGAAGATAGCTCCTCGGAATTGAGCGTGCGCCATTTCAAAGTGGAGCGAAAAGTGAAACGCGCCCGATCGCAGTCACAAAATGAGAGCCAAAGCGAGGATGAAGCATTCAAAGTGGAACCCTTTAATTTTGTGCTGATCAAGGAATCTGATAATATTGGCGATCTGTACGAGTATTTGGGAACCGTGGTGAAGACCTGTTTTGAGACTTTGATCTTTGACTGGGACACTGTGTGCCGCCACTGCTCGCTGAAGTGCAGCAAATATGAAAGTTTATTCGGTCACATGCTGAAGCGTCACAAGGGGCCGGACGATATTTACAAGTGTCCGATTGCTGACTGCGCGACAGAGCTGCAGGGAGCCAAATCCTTGGCCATGCACCTGGTTGTGCTGCATGCCCCGGTAGCCGATATACCCATTTATGGCAGTTGTCCCGAATGCAACATGACCTTCTCAAACATATTGCAGTACAACAAGCACTCCTGCGCGCATGTCATCAAAAAGCGACGCGGCATACGCCTGTATTGTGAGATGTGCGGCTTGGAGTTCCCCTCCTGGAAGCGCTTTAATTTTCacaatcaatttcatttggagCGTCACAGGCCGCGCGCGTGTTTTGTGTGCAGCTACGCGGATACCAACATCGATGAGCTGTTCCATCATTTGCACTACGCTCACGAGCCAGAGGGCACGCTCTTCTGTGACCTCTGTGATCGCAATTTTCGGGATCCTGCCGTCTTTTTGGAGCACAACAAATCACACTCGAATGTCAGCAGTACCACGTACAGCTGCACCGAATGCAGCGCCAATTTTGAGTCACGTGGTCGCCTCAATGGACACCTGCGCACCGCACATGGCAGCGTCATCAGCTGCGAAATGTGCGGCCGCGAGTTTGCCACAGAGGCCACATACAACCTGCACATGAAAACGCATCTGATTATTGAACGCGAGGTGCATGTGTGCAACAATTGTGGTCTGCTCAGTGAAAATAATGACAGGATGCTGGCTCATGTGGCGGAAGAGGATTCGAGTTGCTTTGGCATGGATGTGGTAGTGGAACTGATGCGTGATGCTTATGTTTGTGAATTTTGCTCCGCCTACTTTAAGCAGAAGAGTGACTTAAGCGCCCATCGCGAATCGGGGGTGCACAAGGATGGCCACTTCTGGTGTCATCCGTGCACAAAGAAGTTCACCGATATGAAGCTCTATCGTCACCATTTGCGCAACTATCAACAATTGCGCACAGATTTTTCGCATCGCCGGCTAGAAATTTGTCTCTACTACATGTGCGACTATGAGAATTGCAGTGAGGCCTATATTAATTGGAATTcgctatacacacacaaacggcGCACGCACGATGCCGTCGAGAAGCAGGAGCCCAAGACGAAAGATAACGAATGGATCTGTCAATTCTGTCAGAAAGTGTGCCGCTCCAAAATGTCGCTCTCGGTTCACGTGGCgcgcagccacaacaacaATAATGTGGTCTGCTCGCTCTGCAAAGCTTCGTATAAGGATGAGGAGGCGCTAAAGAAGCATCACGCCTATTGGCATGAGCGCATAGAGTGTCCGATGTGCTTGAAGGTGGTGAAGAATCGTCGCAACTtcgacacacacataaaggTGGTGCACTCAAACAATAAGCGTTACTCGTGCAGTGAATGCCAAAAAGGTTTCTATCACAAGAGCGAAATGGAGGCGCATCAGCGGCTGCATTCCCAATCGTTCAAATGCGAACAGTGCAACTTCACCACGAGGAACAAGAAATCGCTGTCGGTTCATGTGCTGGGTCAGCACTACAAGCGTTTTGCCTTCAAGTGTAAGTTCTGTGAGAAGCGCTTTGGACGCCGCCAGGGACTATCGAATCATATTCTACGTGTGCATGGCTCGAAATATACATGTCGCGACTTCTTCGACGGCGGTTGTGGCAAATCATTTGGCTCGACGGCACGCCTCAACGTGCATGTGCGAAAGGCGCATAACAGCAGCCTCTTTCTGACCGATGACCCAGCCAAATCGGAGGAAAACGaagatgaggaggaggaggaggaggagccgGCTATGGTGGATTCGGCAAGCGAAGGTCCGTCGACATCGAAGAAACGTTTAATTCGCATCAATGCGAACactgaaattgaattcattgGCGATGCAGCTGATGCCGAGGACGACAACGAGAGTCTGACTGATTCGGAAATCTTCGAAGAGTTTGAAGAGATCAAAGCAGTAACAAAACAGCcaccaaaaaagaaaccaaagcCAATGACAACGAGAGCATGA
Protein Sequence: MSENVKTDENVPSCLHCRVYNSKQKYHEIFDEVGIEIELAKLLDRYFEVKVEPAGQKQKQLLCEECVNTLIRFFDIDELQREQDAANGANKKPSNDTKSSALKKDESPAKKQTAAEKNAQGSPNTSANAAIKQEKPTAAAAAIATTAAAPDDIKKGAPEAVGIRITRARNAPPKRLPINMKKAVKRSGTLNGKVDVKRSRSREAAQGSGDQEQISALIRDILEDEESPADEKLVEAAATVRQLEKQSAEEQRQLEEAVEEEQAVLEDQDNNDELEFLVEREDSSSELSVRHFKVERKVKRARSQSQNESQSEDEAFKVEPFNFVLIKESDNIGDLYEYLGTVVKTCFETLIFDWDTVCRHCSLKCSKYESLFGHMLKRHKGPDDIYKCPIADCATELQGAKSLAMHLVVLHAPVADIPIYGSCPECNMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCSYADTNIDELFHHLHYAHEPEGTLFCDLCDRNFRDPAVFLEHNKSHSNVSSTTYSCTECSANFESRGRLNGHLRTAHGSVISCEMCGREFATEATYNLHMKTHLIIEREVHVCNNCGLLSENNDRMLAHVAEEDSSCFGMDVVVELMRDAYVCEFCSAYFKQKSDLSAHRESGVHKDGHFWCHPCTKKFTDMKLYRHHLRNYQQLRTDFSHRRLEICLYYMCDYENCSEAYINWNSLYTHKRRTHDAVEKQEPKTKDNEWICQFCQKVCRSKMSLSVHVARSHNNNNVVCSLCKASYKDEEALKKHHAYWHERIECPMCLKVVKNRRNFDTHIKVVHSNNKRYSCSECQKGFYHKSEMEAHQRLHSQSFKCEQCNFTTRNKKSLSVHVLGQHYKRFAFKCKFCEKRFGRRQGLSNHILRVHGSKYTCRDFFDGGCGKSFGSTARLNVHVRKAHNSSLFLTDDPAKSEENEDEEEEEEEPAMVDSASEGPSTSKKRLIRINANTEIEFIGDAADAEDDNESLTDSEIFEEFEEIKAVTKQPPKKKPKPMTTRA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00496807;
90% Identity: iTF_00501963;
80% Identity: -