Xtog039113.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Xanthia togata
Gene Symbol
Bcl11a
Assembly
GCA_963853775.1
Location
OY970809.1:7335816-7348740[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0034 0.47 12.6 2.2 2 23 73 94 72 94 0.96
2 12 0.025 3.6 9.8 0.5 2 23 101 123 100 123 0.93
3 12 1 1.4e+02 4.8 0.2 2 23 131 153 130 153 0.89
4 12 0.00025 0.036 16.1 5.2 1 23 159 181 159 181 0.97
5 12 7.7e-08 1.1e-05 27.2 2.2 1 23 187 209 187 209 0.96
6 12 0.014 2 10.6 1.2 1 20 215 234 215 236 0.93
7 12 0.2 29 7.0 2.4 3 19 253 269 252 274 0.92
8 12 2.9e-05 0.0041 19.1 1.1 1 23 600 622 600 622 0.98
9 12 4.9e-06 0.00069 21.5 6.7 1 23 629 651 629 652 0.96
10 12 0.039 5.5 9.2 6.2 1 23 660 683 660 683 0.93
11 12 0.0096 1.3 11.1 3.7 2 23 690 713 689 713 0.93
12 12 0.00055 0.078 15.0 1.0 1 21 719 739 719 740 0.95

Sequence Information

Coding Sequence
ATGGATTCGAATTTACCATTTTTTAGTCTCCCAttCGTGGATTCGGAGACTTCAGACTTTTTCTCGAGGATCAAGCCGCAGGAGTGTGCGTACGATGAGTTGCATCCGACTTTACCATCCCACGGTGCTTTGTTGGGGCCTGACGATGTCTTGGCCCAGTTTCTTTCTGGAGACGAACCGTTGGAGGAGCCCGACTTGAACGGGCCTACTACGTTACACTGTGAAATCTGCAAGAAGCGGTTTGATAATGCTAAGAAGTATTATGGACATTTGAGGATCCATTCCAAGGATAACCTTTGGGTTTGTGAGCAATGTCCCGACCAGAAGTTCTCGACCAAGCAGCAGCTGATGAAACACAGCCTCAGTCACAAGCCTCTGGAGAGAGAGTGGAAGTGTCTGCAGTGCACCATGGCCTTTGAGGCTCTGTGGAAACTACAGCAGCATCTGTTTGCCAAGCATTTGAACTACAAGCCTCACAAGTGTGATAAATGTGAGAAGTCTTTCACTAAGGCTTCAGACTTGGACAAACATAAACACATACATAATGATTTAAAGAGGCATGCCTGTCCTGAATGCGACATGCGTTTCAAGGATAAGTCGAATCTGAAGCGCCACATGCTGCGGCACAGTGGGGACAAGCCTTACTGCTGCGCGGGATGCGGAAATCGGTTTAAACAGCTGGCTTCCATGAAGCGTCACTCACAAAACTGCGGGCTCTTGAAGGAGTCGGTGGACAAGAGCACTCGCATGAACCACTGTCGCGTGTGTGGCATGAGCTTCCAGTACAAGAGCGCTTTGTTGGAGCATTGTGTCAGGCAACACACCAACACGGGGGGTGTTGCGCAAAACGCAAAACCGCCCGAACCCGATAAAGAAGATAAAACTCATCTAAACGATACAAACCGCATTGTGGACAATATAGTGGACGATATTCTATCCGCTGAAGACGACTACATGACCATGTCGACACAAAACGAAATACTCAATGTTTACAACCCAAACGATATCGACAATAACCCAGAAAACTTAATGCAAATAGAACTATTAAAAGAAATGAATCAACTACATATTTTAGACGGAGAACTATTCTATAATGACATAGATTTTGATAGCATTCAACCTAGTCACATGTTTAATACCAACACTAATGATATGGATTATGGTACGGATAAAAATGCTGAAATTTTATTCGATTTTACTGAAGGAAGCAAGAGTATGGATCAGGATATAATGAACACTTTATTCCATGTCAAAGCTGAGTACTTACCTGATGAACTACTGAACCCTCCTGAAATTATAAATCCTCCTGAAAAAACTAACGAATTAGACAACCATAATCACGTATCGGTAAATGAATGTGCCACTATATTTGAAAGTGACGTTGATTTAGAAGCTAGTACGAATCTAGCTGCAAATTTGAACCAGCTCATCGGAGAAAATAGTGTCCAATACATTTCTACAGAAGACGATGATACTTTTATAATAAGTTTGAATAGCGAAATTGATGCTGAGCAGCTAACGGATATGTTAAATATAGGGGTTGAGTTAGTTAATGATAAGGCTAAAGAGCCAAGTATACCTGAAGTTAAGAAGGAGCCTGTAAGTCCAGGAAATATAGAGCTTTATGTAAAGATTGAAAAGCCTAAAGTAAAAGAGCCCCAAAATGAGCAACTAGAAGGTCGATTACACAAACCTATGGTCGTTAAAATTGAAGAGGATATGAGTGTCCCCCCAGTGAGTTTGATGGCTACAGAAGAGAAAAAAGTAATAAAGAGGAAGCCGAAGAAGACAGTGTTGTATGTTTGTAGAACATGCAATAAGGTGTTCAATAAGAATGATAATTATATGTCTCATATAGGGACTCACGAGCCGTCCCTTCGCCGCCACAAGTGTAAGATCTGCGGCGAGCGCTTCAGTTACCGCTCCACACTGAACAAGCACACGCGCAGCCACCACACGCCCTACGTGCAGTCCGAGCATTGCTGTCACATATGTGACCGGTACTTCTCGTTCGCGTGGATGTTGAGAAACCATTTCGAGCGCGACCACGACGGCCTGACACCGCATGCGTGCGACTATAAGGACTGTCGTAAGCGGTTCTTCAAGAAATCAGACCTGGTCGTGCATAAGAGGTACCACACTGGAGAGCGTCCGTATTCCTGCGATATCTGCAAGAGAGCGTTCTTGCACGCGAGTCATCTCAGGCGCCACGAGCGGGCAGTCGACTGCAACAAGTTGTAA
Protein Sequence
MDSNLPFFSLPFVDSETSDFFSRIKPQECAYDELHPTLPSHGALLGPDDVLAQFLSGDEPLEEPDLNGPTTLHCEICKKRFDNAKKYYGHLRIHSKDNLWVCEQCPDQKFSTKQQLMKHSLSHKPLEREWKCLQCTMAFEALWKLQQHLFAKHLNYKPHKCDKCEKSFTKASDLDKHKHIHNDLKRHACPECDMRFKDKSNLKRHMLRHSGDKPYCCAGCGNRFKQLASMKRHSQNCGLLKESVDKSTRMNHCRVCGMSFQYKSALLEHCVRQHTNTGGVAQNAKPPEPDKEDKTHLNDTNRIVDNIVDDILSAEDDYMTMSTQNEILNVYNPNDIDNNPENLMQIELLKEMNQLHILDGELFYNDIDFDSIQPSHMFNTNTNDMDYGTDKNAEILFDFTEGSKSMDQDIMNTLFHVKAEYLPDELLNPPEIINPPEKTNELDNHNHVSVNECATIFESDVDLEASTNLAANLNQLIGENSVQYISTEDDDTFIISLNSEIDAEQLTDMLNIGVELVNDKAKEPSIPEVKKEPVSPGNIELYVKIEKPKVKEPQNEQLEGRLHKPMVVKIEEDMSVPPVSLMATEEKKVIKRKPKKTVLYVCRTCNKVFNKNDNYMSHIGTHEPSLRRHKCKICGERFSYRSTLNKHTRSHHTPYVQSEHCCHICDRYFSFAWMLRNHFERDHDGLTPHACDYKDCRKRFFKKSDLVVHKRYHTGERPYSCDICKRAFLHASHLRRHERAVDCNKL