Basic Information

Insect: Mythimna loreyi
Gene Symbol: topi
Assembly: GCA_029852875.1
Location: CM056797.1:5077230-5092787[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.003 0.27 12.6 2.1 2 23 73 94 72 94 0.96

2 12 0.049 4.3 8.8 0.4 2 23 101 123 100 123 0.94

3 12 0.39 34 6.0 0.4 2 23 131 153 130 153 0.90

4 12 2.9e-05 0.0025 19.0 2.2 1 23 159 181 159 181 0.96

5 12 7.5e-08 6.6e-06 27.1 2.2 1 23 187 209 187 209 0.96

6 12 0.00062 0.054 14.8 1.3 1 20 215 234 215 236 0.93

7 12 0.2 18 6.9 2.4 3 19 256 272 255 277 0.92

8 12 3.2e-06 0.00028 22.0 1.4 1 23 596 618 596 618 0.98

9 12 4e-06 0.00035 21.7 4.2 1 23 625 648 625 648 0.97

10 12 0.015 1.3 10.4 5.1 1 23 656 679 656 679 0.95

11 12 0.0069 0.6 11.5 4.7 1 23 685 709 685 709 0.96

12 12 0.00063 0.055 14.8 1.0 1 20 715 734 715 736 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.003	0.27	12.6	2.1	2	23	73	94	72	94	0.96
2	12	0.049	4.3	8.8	0.4	2	23	101	123	100	123	0.94
3	12	0.39	34	6.0	0.4	2	23	131	153	130	153	0.90
4	12	2.9e-05	0.0025	19.0	2.2	1	23	159	181	159	181	0.96
5	12	7.5e-08	6.6e-06	27.1	2.2	1	23	187	209	187	209	0.96
6	12	0.00062	0.054	14.8	1.3	1	20	215	234	215	236	0.93
7	12	0.2	18	6.9	2.4	3	19	256	272	255	277	0.92
8	12	3.2e-06	0.00028	22.0	1.4	1	23	596	618	596	618	0.98
9	12	4e-06	0.00035	21.7	4.2	1	23	625	648	625	648	0.97
10	12	0.015	1.3	10.4	5.1	1	23	656	679	656	679	0.95
11	12	0.0069	0.6	11.5	4.7	1	23	685	709	685	709	0.96
12	12	0.00063	0.055	14.8	1.0	1	20	715	734	715	736	0.94

Sequence Information

Coding Sequence: ATGGATTCGAATTTACCATTTTTTAGTCTCCcattcgTGGATTCGGAGACTTCAGATTTTTTATCGAGGATCAAGCCGCAAGAGTGTGCGTACGATGAATTACACGCAACTTTACCGTCCCATGGGGCTTTGCTGGGCCCCGACGATGTGTTGGCCCAGTTTCTTTCTGGAGACGAACCTCTAGAGGAGCCCGATCTAAATGGCCCTACTACATTACACTGTGAGATCTGTAAGAAACGGTTCGATAATGCTAAGAAGTACTATGGACATTTACGAGTCCATTCCAAGGATAATCTTTGGGTTTGTGAACAATGTCCCGACCTGAAGTTTTCCACCAAGCAGCTGCTGATGAAACATAGCTTGACTCACAAGCCCCTGGAGAGAGAATGGAAGTGTCTGCAGTGCACGATGGCCTTTGAGGCTCTGTATAAACTGCAGCAACACCTCTTTGCCAAGCATTTGAACTACAAACCACACAACTGTGACCAATGCGAGAAGTCTTTTACAAAGGCTTCAGACTTGGAGAAGCATAAGAGCATACATAGTGATGTGAAGAGACATGCGTGTCCGGAATGCGACATGCGCTTCAAGGACAAGTCCAACCTCAAGCGGCACATGCTCCGACACAACAACACCAAGCCCTATTGCTGCACAGGATGTGGGACCAGGTTTAAACAGCTGGCGTCCATGAAACGCCACGCGCAGAACTGCGCGCTCAACAAAGGTTGTAGCGAGCCGGCGGAGACGCGCACTCGCAAGAACCACTGCCGAGTGTGCGGCATGAGCTTCCAGTACAAGAGCGCCTTGTTGGAGCACTGTGTCAGGCAACATACGGAAGGGGGGAGTGTTGCTCAAAACGCGAAGCCGCCAGAACCCGACAAGGATGACAAAAGCAATCTTAACGATACGAACCGCATAGTAGACAACATCGTGGACGATATCCTCTCCGCTGAAGACGACTACATGACCATGTCGACACAGAACGAGATACTAAACGTCTACAACCCAAATGATATCGACAACCCAGAAAACTTGATGCAAATTGAACTATTAAAAGAAATGAATCAACTCCACATTTTAGATGGAGAACTCTTCTACAATGATATAGACTTCGACAGCATCCAACCTAGTCACATGTTCAACACAAACACCAATGACATGGACTATAGTGCCGATAAGAATGCTGAGATTCTCTTCGATTTCACTGAAGGAAACAAAAGTATGGATCAAGATATCATGAACACTTTGTTTCATGTCAAAGCTGAGTACTTACCTGATGAACTACTAAATCCACCAGAAATAATCAATCCTCCTGAGAAAAATAATGAACTAGATAATCATAACCACGTATCTGTGAATGAATGTGCTACAATATTTGAAAGTGACGTTGATTTAGAAGCTAGTACAAATCTAGCTGCAAATTTGAACCAACTGATTGGCGAAAATAGCGTACAATACATTTCTACAGAAGACGATGATACCTTTATAATTAGTTTAAATAGTGAAATTGATGCAGAACAGCTCTCGGATATGTTAAATATAGGAGTAGAGTTAGTTAATGATAAGACTAAGGAGCCAAGTGTACCTGAAGTTAAGCAGGAAACTGTAAGCTTAGCAAATATAGAGCTTTATGTTAAGATTGATAAGCCAAAAGAGCCACAGAAAGAGCAATTGCGGCCTATGGTCTTTAAAGTGGAGGATCCTATGAGTGTACCGCCTATGAATTTCGCACCCACAGAGGAGCAAAAGAAAGTAACGAAGAGAAAGCCTAAGAAAAGAAAGTTATACGTTTGTAAGACTTGCAATAAGGCGTTCAATAAGAATGATAACTACAAATCTCATATAGCAACCCACGAGCCGTCTCTGCGGCGGCACAAGTGCAAGGTGTGCGGGGAGCGCTTCAGCTACCGCTCCACGCTCAACAAGCACACGCGCAGCATGCACACGCCCTACGTGCAGGAGGAGCACTGCTGCCACATCTGCGAGCGCAACTTCAAGTTCGCCTGGATGTTACGAGAGCACTTAGAACGCGACCACGACGGCCTGACACCGCATACGTGTGACTATAAAGACTGTCGCAAAAGTTTCTTCAAGAAATCAGATCTCGTCGTGCATAAGAGGTTCCACACTGGCGAGCGTCCATACTCGTGCGACATCTGCAAGAGACGGTTCCTTCAGGCGAGCCATCTCAAGCGACACGAGAAGGCCGTCGACTGTACCAAGTTCGTTGACAAATCGGAACCGCTGCCTCAAAAAGAAAAGGAGTCCTCAACAAAGAGCATAAACtgtgatattaaaattaaacgataa
Protein Sequence: MDSNLPFFSLPFVDSETSDFLSRIKPQECAYDELHATLPSHGALLGPDDVLAQFLSGDEPLEEPDLNGPTTLHCEICKKRFDNAKKYYGHLRVHSKDNLWVCEQCPDLKFSTKQLLMKHSLTHKPLEREWKCLQCTMAFEALYKLQQHLFAKHLNYKPHNCDQCEKSFTKASDLEKHKSIHSDVKRHACPECDMRFKDKSNLKRHMLRHNNTKPYCCTGCGTRFKQLASMKRHAQNCALNKGCSEPAETRTRKNHCRVCGMSFQYKSALLEHCVRQHTEGGSVAQNAKPPEPDKDDKSNLNDTNRIVDNIVDDILSAEDDYMTMSTQNEILNVYNPNDIDNPENLMQIELLKEMNQLHILDGELFYNDIDFDSIQPSHMFNTNTNDMDYSADKNAEILFDFTEGNKSMDQDIMNTLFHVKAEYLPDELLNPPEIINPPEKNNELDNHNHVSVNECATIFESDVDLEASTNLAANLNQLIGENSVQYISTEDDDTFIISLNSEIDAEQLSDMLNIGVELVNDKTKEPSVPEVKQETVSLANIELYVKIDKPKEPQKEQLRPMVFKVEDPMSVPPMNFAPTEEQKKVTKRKPKKRKLYVCKTCNKAFNKNDNYKSHIATHEPSLRRHKCKVCGERFSYRSTLNKHTRSMHTPYVQEEHCCHICERNFKFAWMLREHLERDHDGLTPHTCDYKDCRKSFFKKSDLVVHKRFHTGERPYSCDICKRRFLQASHLKRHEKAVDCTKFVDKSEPLPQKEKESSTKSINCDIKIKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01527643;
90% Identity: iTF_01030495;
80% Identity: -