Basic Information

Insect: Polia nebulosa
Gene Symbol: topi_1
Assembly: GCA_951329385.1
Location: OX589606.1:8527192-8539186[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0031 0.53 12.7 2.1 2 23 73 94 72 94 0.96

2 12 0.012 2 10.9 0.5 2 23 101 123 100 123 0.94

3 12 1 1.7e+02 4.8 0.2 2 23 131 153 130 153 0.89

4 12 2.9e-05 0.0051 19.0 2.2 1 23 159 181 159 181 0.96

5 12 9.1e-08 1.6e-05 26.9 1.8 1 23 187 209 187 209 0.96

6 12 0.0048 0.82 12.1 1.3 1 20 215 234 215 236 0.93

7 12 0.071 12 8.4 1.2 3 19 262 278 261 283 0.91

8 12 1.9e-05 0.0032 19.6 1.8 1 23 607 629 607 629 0.98

9 12 0.00013 0.023 17.0 4.1 1 23 636 659 636 659 0.97

10 12 0.04 6.8 9.2 3.5 1 23 667 690 667 690 0.95

11 12 0.0044 0.76 12.2 2.7 2 23 697 720 696 720 0.93

12 12 0.00064 0.11 14.8 1.0 1 20 726 745 726 747 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0031	0.53	12.7	2.1	2	23	73	94	72	94	0.96
2	12	0.012	2	10.9	0.5	2	23	101	123	100	123	0.94
3	12	1	1.7e+02	4.8	0.2	2	23	131	153	130	153	0.89
4	12	2.9e-05	0.0051	19.0	2.2	1	23	159	181	159	181	0.96
5	12	9.1e-08	1.6e-05	26.9	1.8	1	23	187	209	187	209	0.96
6	12	0.0048	0.82	12.1	1.3	1	20	215	234	215	236	0.93
7	12	0.071	12	8.4	1.2	3	19	262	278	261	283	0.91
8	12	1.9e-05	0.0032	19.6	1.8	1	23	607	629	607	629	0.98
9	12	0.00013	0.023	17.0	4.1	1	23	636	659	636	659	0.97
10	12	0.04	6.8	9.2	3.5	1	23	667	690	667	690	0.95
11	12	0.0044	0.76	12.2	2.7	2	23	697	720	696	720	0.93
12	12	0.00064	0.11	14.8	1.0	1	20	726	745	726	747	0.94

Sequence Information

Coding Sequence: ATGGATTCGAATTTACCATTTTTTAGTCTCCCATTTGTGGATTCGGAGACTTCAGATTTTTTGTCGAGGATCAAGCCGCAGGAGTGTGCGTATGATGAGTTGCACGCGACTCTACCGTCCCACGGGGCCTTGCTGGGGCCCGACGATGTCTTGGCCCAGTTTCTTTCTGGAGACGAACCATTGGAGGAGCCCGATCTGAACGGCCCTACTACGTTACACTGTGAGATCTGTAAAAAGCGGTTTGATAATGCTAAGAAGTATTACGGACATTTGAGAGTTCATTCCAAAGATAATCTTTGGGTTTGTGAGCAATGTCCAAATCAGAAGTTTTCAACAAAGCAGCAGCTGATGAAACATGGCCTGACACACAAGCCCCTCGAGAGGGAGTGGAAGTGTCTGCAGTGCACCATGGCCTTCGAGGCTCTGTGGAAACTGCAGCAGCACCTGTTTGCCAAGCATTTGAACTACAAGCCCCACAACTGTGATCAATGCGAGAAGTCTTTCACTAAGGCTTCGGACTTGGAGAAACATAAGAGCATTCATAGTAATGTAAAGAAGCATGCGTGTCCAGAGTGTGACATGCGCTTCAAGGACAACTCGAACCTGAAGCGGCACATGCTGCGGCACAGCGGCATCAAGCCTTACTGCTGTACCGGAtgtggaagtcggtttaaaCAGCTGGCATCAATGAAGCGTCACGCGCAGAACTGCGCGCTCAGCAAGTGTTCCGCCCTCAGCAAGAGCTCCGCCGACGTCGCCGACGTGCGCACGCGCAGGAACTACTGCCGAGTGTGCGGCATGAGCTTCCAGTACAAGAGCGCCTTGCTAGAGCACTGTGTCCGACAACATACGGACGCGGGGGGAGCTCCACAGAACGTAAAACCGCCCGAACCTGATAAAGATGACAAAAGCAATTTGAACGACACCAACCGCATCGTAGACAACATTGTGGACGATATCCTCTCCGCAGAAGACGACTACATGACCATGTCCACACAGAACGAAATACTTAACGTCTACAACCCGAATGATATCGACAACAACCCAGAGAACTTGATGCAAATAGAGCTATTAAAGGAAATGAATCAACTACACATTCTAGACGGAGAACTGTTCTACAATGACATAGACTTCGATAGCATTCAACCTAGCCACATGTTCAACACAAACACTAATGATATGGATTATAGTACCGATAAGAATGCTGAGATTCTATTCGATTTTACTGAAGGCAGCAAAAGTATGGACCAAGATATCATGAACACTCTATTTCACGTCAAAGCTGAGTACTTACCCGACGAATTACTAAATCCAACTGAAATTATAAATCCTACTGAGAAAAATAACGAATTAGAACAACATAACCATGTGTCGGTGAACGAATGTGCTACAATATTTGAGAGCGACGTTGATTTAGAAGCTAGCACTAATTTAGCAGCAAATTTGAACCAACTCATCGGCGAGAATAATGTCCAGTACATTTCAACAGAAGACGATGATACTTTTATAATTAGTTTGAATAGTGAAATTGATGCGGAACAGTTAACGGATATGTTAAATCTAACTCCTATAGGAGTTGAATTAGTTAATGATAAAACTAAGGAGCCTACTGTACCCGAAGTTAAGCAGGAAACTGTGAGTCTAGCAAATATAGAGCTGTATGTCAAGATTGATAAGCCAGTGAAACAGCCTCAGAATGAGCAAGTAAGGCCTATGGTCATTAAACTGGAAGAGCCTATTGCTGTACCGCCTATGAGTTTGGTTGCCacagaagagaaaaagaaagtaaaaatgGAAAAGCCTAAGAAGAGAGTGTTATATGTTTGTAGAACTTGCAATAAGGCTTTCAATAAGAAAGATAATTATAGATCTCATCTAGCAACCCACGAGCCCGGCCTGCGGCGCCACAAGTGCAAGGTGTGCGGCGACCGCTTCAGCTACCGCTCCACGCTCAACAAGCACACGCGCAGTCTGCACACGCCCTACGTGCAGGACGAGCACTGCTGCCAGTTATGCGAGCGGAACTTCAAGTTCGCGTGGATGTTGAGAGAGCACCTGGAGCGCGACCACAAGGGCCTGACGCCGCACGCCTGCGACTACGAGGACTGTCGCAAGAGCTTCTTCAAGAAATCTGACCTCGTCGTGCATAAGagGTTCCACACTGGCGAGCGTCCGTACTCGTGCGATATCTGCAAGAGAAGGTTCCTCCAAGCGAGCCATCTCAAGCGGCATGAGAAGGCCGTCGACTGCACCAAGTTGTAA
Protein Sequence: MDSNLPFFSLPFVDSETSDFLSRIKPQECAYDELHATLPSHGALLGPDDVLAQFLSGDEPLEEPDLNGPTTLHCEICKKRFDNAKKYYGHLRVHSKDNLWVCEQCPNQKFSTKQQLMKHGLTHKPLEREWKCLQCTMAFEALWKLQQHLFAKHLNYKPHNCDQCEKSFTKASDLEKHKSIHSNVKKHACPECDMRFKDNSNLKRHMLRHSGIKPYCCTGCGSRFKQLASMKRHAQNCALSKCSALSKSSADVADVRTRRNYCRVCGMSFQYKSALLEHCVRQHTDAGGAPQNVKPPEPDKDDKSNLNDTNRIVDNIVDDILSAEDDYMTMSTQNEILNVYNPNDIDNNPENLMQIELLKEMNQLHILDGELFYNDIDFDSIQPSHMFNTNTNDMDYSTDKNAEILFDFTEGSKSMDQDIMNTLFHVKAEYLPDELLNPTEIINPTEKNNELEQHNHVSVNECATIFESDVDLEASTNLAANLNQLIGENNVQYISTEDDDTFIISLNSEIDAEQLTDMLNLTPIGVELVNDKTKEPTVPEVKQETVSLANIELYVKIDKPVKQPQNEQVRPMVIKLEEPIAVPPMSLVATEEKKKVKMEKPKKRVLYVCRTCNKAFNKKDNYRSHLATHEPGLRRHKCKVCGDRFSYRSTLNKHTRSLHTPYVQDEHCCQLCERNFKFAWMLREHLERDHKGLTPHACDYEDCRKSFFKKSDLVVHKRFHTGERPYSCDICKRRFLQASHLKRHEKAVDCTKL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01527643;
90% Identity: iTF_01030495;
80% Identity: -