Basic Information

Insect: Noctua pronuba
Gene Symbol: Bcl11b
Assembly: GCA_905220335.1
Location: LR999912.1:11537493-11552082[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0026 0.24 12.6 2.1 2 23 73 94 72 94 0.96

2 12 0.015 1.4 10.2 0.2 2 23 101 123 100 123 0.93

3 12 0.86 79 4.7 0.2 2 23 131 153 130 153 0.89

4 12 7.4e-05 0.0069 17.5 1.8 1 23 159 181 159 181 0.97

5 12 1.5e-07 1.4e-05 25.9 1.5 3 23 189 209 189 209 0.99

6 12 0.0075 0.69 11.2 2.4 1 20 215 234 215 236 0.93

7 12 0.0036 0.33 12.2 0.3 3 23 255 276 254 276 0.93

8 12 4.2e-06 0.00039 21.4 1.7 1 23 608 630 608 630 0.98

9 12 1.7e-06 0.00016 22.6 4.1 1 23 637 660 637 660 0.97

10 12 0.01 0.93 10.8 3.8 1 23 668 691 668 691 0.95

11 12 0.0021 0.19 12.9 4.4 1 23 697 721 697 721 0.96

12 12 4.8e-06 0.00044 21.2 0.9 1 21 727 747 727 748 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0026	0.24	12.6	2.1	2	23	73	94	72	94	0.96
2	12	0.015	1.4	10.2	0.2	2	23	101	123	100	123	0.93
3	12	0.86	79	4.7	0.2	2	23	131	153	130	153	0.89
4	12	7.4e-05	0.0069	17.5	1.8	1	23	159	181	159	181	0.97
5	12	1.5e-07	1.4e-05	25.9	1.5	3	23	189	209	189	209	0.99
6	12	0.0075	0.69	11.2	2.4	1	20	215	234	215	236	0.93
7	12	0.0036	0.33	12.2	0.3	3	23	255	276	254	276	0.93
8	12	4.2e-06	0.00039	21.4	1.7	1	23	608	630	608	630	0.98
9	12	1.7e-06	0.00016	22.6	4.1	1	23	637	660	637	660	0.97
10	12	0.01	0.93	10.8	3.8	1	23	668	691	668	691	0.95
11	12	0.0021	0.19	12.9	4.4	1	23	697	721	697	721	0.96
12	12	4.8e-06	0.00044	21.2	0.9	1	21	727	747	727	748	0.95

Sequence Information

Coding Sequence: ATGGATTCGAATTTACCATTTTTTAGTCTCCCATTCGTGGATTCGGAGACTTCAGATTTTTTGTCGAAGATCAAGCCGCAGGAGTGTGCCTACGATGAGTTGCACGCCACGTTACCATCCCATGGTGCTTTGTTGGGCCCTGACGATGTCTTGGCCCAGTTTCTATCTGGAGACGAACCGTTGGAGGAGCCCGACTTGAACGGTCCTACTACGTTGCACTGTGAGATCTGTAAGAAGCGGTTTGACAATGCTAAGAAGTATTATGGACATTTGAGAGTCCATTCCAAGGATAATCTTTGGGTTTGTGACCAATGTCCCGACCAGAAGTTCTCGACGAAGCAGCAACTTATGAGACATGGCTTGATCCACAAGCCGCTGGGCAGGGAGTGGAAGTGTCTGCAGTGCACCATGGCTTTCGAGGCCCTGTGGAAGCTGCAGCAGCATCTGTTTGCTAAGCATTTGAACTACAAGCCTCATAAGTGCGATCAATGTGAGAAGGCTTTCACTAAGGCTTCAGACCTGGACAAACATAAAAGTATACATAGTGATCTGAAGAGGCATGGATGTCCTGAATGTGATATGCGTTTCAAAGACAAGTCGAATCTGAAGCGACACATGCTGCGACACAACAGGGTTAAGCCTTACTGCTGTTCCGGTTGCGGAAATCGATTTAAACAGCTCGCATCAATGAAGCGTCACGCGCAGCACTGCTCGCTCAACAAGGAGTCCAGCGAGGCAGACAGGGGCACTCGCAAGAACTACTGCCGCGTGTGTGGCATGAGCTTCCAGTACAAGAGCGCCTTGTTAGAGCACTACGTCAGGCAACACACCAACACGGGGGCGGTTGCGCAAAACGCAAAACCGCCGGAACCCGACAAAGAAGATAAGAGCCATCTGAACGACACAAACCGCATCGTAGACAACATTGTGGACGACATCCTGTCCGCTGAGGACGATTACATGACCATGCCGACACAAAACGAGATACTCAACGTTTACAACCCAAATGATATCGATAATAACCCAGAAAACTTAATGCAAATCGAATTATTAAAAGAAATGAATCAACTACACATTTTAGACGGAGAACTTTTCTACAATGACATAGATTTTGACAGCATTCAACCTAGTCACATGTTTAATACTAACACAAATGATATGGATTACGGTACCGATAAAAACGCTGAAATCTTATTCGACTTTACCGATGGAAGCAAAAGTATGGACCAGGATATCATGAACACTTTATTTCATGTCAAAGCTGAGTACTTACCTGACGAACTATTGAATCCACCAGAAATTGTAAATCCTCCTGAGAAAAGTAACGAATTAGAAAATCCCAATCATGTATCTGTGAACGAATGCGCTACGATATTTGAAAGTGACGTTGACTTAGAAGCTAGCACAAATCTAGCTGCAAACTTAAACCAGCTGATCGGTGAAAATAGTGTCCAATACATTTCTACAGAGGACGATGATACATTTATAATAAGTTTAAATAGCGAAATTGATGCCGAACAATTAACCGATATGTTAAACATTGGCGTAGAGTTAGTCAATGATAAGAATAAGGAGCCAAGTATACCCGGTATACCCGAAATAAAACAAGAACATGTAAGTCTAGCCAATGTAGAGCTCTATGTTAAGTTTGAAAAGCCATTACAAGTGAAAGAGCCCCAAAATAAGCATATAGAAGAGCGCTTAACACACCGGCCTATGGTCGTTAAAATTGAAGAGCCTATGAGTGAACCACCAATGAGTTTGATGGCCACGGAAGAGAAGAAGAAGGTTATTAAGAAGAAGCCTAAGACCAGGGTGCTGTATGTTTGTAGAACATGCAACAAGGTGTTTAAGAAGAATGATAATTATAGGTCTCATATAGCAACGCACGAGCCATCTCTTCGGCGGCACAAGTGCAAGATCTGCGGCGAACGCTTCAGCTACCGCTCCACGCTGAACAAGCACACGCGCAGCCTCCACACGCCTTACGTCCCGCAGGAGCATTGCTGCCAGATATGTCAACGCAACTTCAAGTTCGCGTGGATGTTGAAAGAGCATTTGGAGCGTGACCACGACAGACTGACGCCGCATACGTGCGACTACAAGGACTGTCGCAAAAGCTTCTTCAAGAAATCGGACCTCGCCGTGCATAAGAGGTACCACACTGGAGAGCGTCCGTATTCCTGCGAGGTGTGCAAGAAAGCGTTCCCCCACGCCAGCCACCTCAAGAGACACGAGCGAGCCGTTGACTGCACCAAGCATTTATGCAAAGCGGAGCTGCGTCCCTCATCACCTCAAATAGAAAAGGAACTTCCGAAGAACAGCTGTGATATTAAAATAAAAATAAATTAA
Protein Sequence: MDSNLPFFSLPFVDSETSDFLSKIKPQECAYDELHATLPSHGALLGPDDVLAQFLSGDEPLEEPDLNGPTTLHCEICKKRFDNAKKYYGHLRVHSKDNLWVCDQCPDQKFSTKQQLMRHGLIHKPLGREWKCLQCTMAFEALWKLQQHLFAKHLNYKPHKCDQCEKAFTKASDLDKHKSIHSDLKRHGCPECDMRFKDKSNLKRHMLRHNRVKPYCCSGCGNRFKQLASMKRHAQHCSLNKESSEADRGTRKNYCRVCGMSFQYKSALLEHYVRQHTNTGAVAQNAKPPEPDKEDKSHLNDTNRIVDNIVDDILSAEDDYMTMPTQNEILNVYNPNDIDNNPENLMQIELLKEMNQLHILDGELFYNDIDFDSIQPSHMFNTNTNDMDYGTDKNAEILFDFTDGSKSMDQDIMNTLFHVKAEYLPDELLNPPEIVNPPEKSNELENPNHVSVNECATIFESDVDLEASTNLAANLNQLIGENSVQYISTEDDDTFIISLNSEIDAEQLTDMLNIGVELVNDKNKEPSIPGIPEIKQEHVSLANVELYVKFEKPLQVKEPQNKHIEERLTHRPMVVKIEEPMSEPPMSLMATEEKKKVIKKKPKTRVLYVCRTCNKVFKKNDNYRSHIATHEPSLRRHKCKICGERFSYRSTLNKHTRSLHTPYVPQEHCCQICQRNFKFAWMLKEHLERDHDRLTPHTCDYKDCRKSFFKKSDLAVHKRYHTGERPYSCEVCKKAFPHASHLKRHERAVDCTKHLCKAELRPSSPQIEKELPKNSCDIKIKIN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01527643;
90% Identity: iTF_00712222;
80% Identity: -