Basic Information

Insect: Mamestra configurata
Gene Symbol: ZEB2
Assembly: GCA_002192655.2
Location: NDFZ01005054.1:110249-118252[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0023 0.22 12.6 2.1 2 23 73 94 72 94 0.96

2 12 0.0089 0.85 10.8 0.6 2 23 101 123 100 123 0.94

3 12 0.3 28 6.0 0.4 2 23 131 153 130 153 0.90

4 12 1.3e-05 0.0012 19.7 2.1 1 23 159 181 159 181 0.96

5 12 2.9e-07 2.8e-05 24.9 1.9 1 23 187 209 187 209 0.96

6 12 0.0014 0.14 13.3 1.0 1 20 215 234 215 236 0.93

7 12 0.15 15 6.9 2.4 3 19 256 272 255 277 0.92

8 12 7.4e-06 0.0007 20.5 1.5 1 23 595 617 595 617 0.98

9 12 1.5e-06 0.00014 22.7 4.1 1 23 624 647 624 647 0.97

10 12 0.00071 0.067 14.3 3.3 1 23 655 678 655 678 0.95

11 12 0.0017 0.16 13.0 2.8 2 23 685 708 684 708 0.92

12 12 0.00048 0.045 14.8 0.8 1 20 714 733 714 735 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0023	0.22	12.6	2.1	2	23	73	94	72	94	0.96
2	12	0.0089	0.85	10.8	0.6	2	23	101	123	100	123	0.94
3	12	0.3	28	6.0	0.4	2	23	131	153	130	153	0.90
4	12	1.3e-05	0.0012	19.7	2.1	1	23	159	181	159	181	0.96
5	12	2.9e-07	2.8e-05	24.9	1.9	1	23	187	209	187	209	0.96
6	12	0.0014	0.14	13.3	1.0	1	20	215	234	215	236	0.93
7	12	0.15	15	6.9	2.4	3	19	256	272	255	277	0.92
8	12	7.4e-06	0.0007	20.5	1.5	1	23	595	617	595	617	0.98
9	12	1.5e-06	0.00014	22.7	4.1	1	23	624	647	624	647	0.97
10	12	0.00071	0.067	14.3	3.3	1	23	655	678	655	678	0.95
11	12	0.0017	0.16	13.0	2.8	2	23	685	708	684	708	0.92
12	12	0.00048	0.045	14.8	0.8	1	20	714	733	714	735	0.94

Sequence Information

Coding Sequence: ATGGATTCGAATTTACCATTTTTTAGTCTTCCATTCGTGGATTCGGAGACTTCTGATTTTTTATCAAGAATCAAGCCACAGGAGTGTGCATATGATGAGTTGCACACGACTTTACCATCCCATGGAGCCTTGCTGGGCCCCGACGATGTCTTGGCGCAGTTTCTTTCTGGAGACGAGCCCCTGGAGGAGCCCGACCTGAACGGTCCTACTACGTTGCACTGTGAGATATGTAAGAAGCGGTTCGATAATGCTAAGAAGTATTACGGACATTTGAGAGTCCATTCCAAGGATAACCTTTGGGTTTGTGACCAATGTCCCGATCAGAAGTTTTCAACAAAGCAGCAGCTCATGAAACACAGCCTGACCCACAAGCCTCTGGAGAGAGAGTGGAAGTGTCTGCAGTGTACGATGGCCTTTGAGGCTCTGTATAAATTACAGCAACACCTGTTTGCCAAGCATTTGAACTACAAGCCCCACAACTGTGATCAATGCGAGAAGTCTTTCACTAAGCCTTCAGACTTGGAGAAACATAAGAGCATACATAGTGATGTAAAGAAGCACGCGTGTCCTGAGTGCGACATGCGCTTCAAGGACAACACGAATCTGAAGCGGCATATGCTGCGGCACAACGGCACTAAGCCCTACTGCTGCAGCGGCTGCGGGACTCGGTTTAAACAGATAGCGTCAATGAAGCGGCACGCGCAGAACTGCGCGCTCAGCAAGTGCGTGAGCGAGGCGGCCGACACGCGCACGCGCAAGAACCACTGCCGCGTGTGCGGCATGAGCTTCCAGTACAAGAGTGCGCTGTTGGAGCACTGTGTGCGGCAACATACAGACGCGGGGGGTGCTGCTCAAAACGCAAAGCCGCCTGAACCCGACAAAGATGATAAAAGCAATCTGAACGACACCAACCGCATCGTAGACAACATTGTGGACGACATCCTGTCCGCAGAAGACGACTACATGACCATGTCGACTCAGAACGAGATACtcaacgtatacaaccctaacgATATCGACAACAACCCAGAAAACTTGATGCAAATAGAACTACTAAAAGAAATGAATCAACTACACATTCTGGACGGAGAACTGTTCTACAATGACATAGACTTCGATAGCATTCAACCTAGCCACATGTTCAATACTAACACAAATGACATGGACTACACTGCCGATAAAAACGCCGAAATTCTGTTCGATTTTACCGAAGGAAGCAAAAGCATGGATCAAGACATCATGAACACTTTATTTCATGTCAAAGCCGAGTACTTACCTGATGAACTACTAAATCCACCTGAAACTATTAATGCTCCTGAGACAAATAACGAATTAGACAATCATAATCATGTATCAGTGAACGAATGTGCTACAATATTTGAAAGTGACGTCGATTTAGAAGCAAGCACGAATCTAGCTGCAAATTTGAACCAACTCATAGGTGAAAATAGCGTCCAGTATATTTCAACGGAAGACGATGATACTTTTATAATTAGCTTAAAAAGTGAAATTGATGCGGAGCAGCTGACGGATATGTTGAATATTGGAGTTGAATTAGTTAATGATAAGACTAAAGAGCCAAGCGTACCTGAGGTTAAACAGGAAATTGTAAGCCTAGCGAATATAGAGCTTTATGTCAAGTTTGATAAGCCTCTGTCAGTAAAAGAGCCCCAGAATGAGCAATTATGGCCTGTGGTCATAAAAATGGAAGAGCCCATGACTTTGATGGCTACAGAAGAGAAGAAGAAAGTTAAAGCAAGAAAGCCTAAGAAGAGAGTGTTATATGTCTGTAGAACTTGCAATAAGGCTTTCAATAAGAAGGATAATTATAGATCTcatatagCAACCCACGAGCCGTCACTCCGCCGTCACAAGTGCAAGATCTGCGGCGAGCGCTTCAGCTACCGCTCCACGCTCAACAAGCACACGCGCAGTCTGCACACGCCCTACGTGCCCGCCGAGCATTGCTGCCAGATATGCGACCGCAACTTCAAGTTCGCGTGGATGTTGCGAGAGCACATGGAGCGCGACCATGACGGCCTGACGCCTCACGCGTGCGACTACAAAGACTGCGGCAAGAGCTTCTTCAAAAAATTCGACCTTGCCGTGCATAAGAGGTTCCACACGGGTGAGCGTCCGTACTCGTGCGAGATCTGCAAGAGGAGGTTCCTGCAAGCGAGTCATCTCAGGCGCCACGAGAAAGCCGTCGACTGCACCAAGTTTATTAGCAAATCGGAGTCTCTTCCATCGCTGGCTCAAAAGGAAAAGGAGACTCCAACAAAGAGTACCAACTGTGATATCAAAATTAAAgatgaattaattttaaattaa
Protein Sequence: MDSNLPFFSLPFVDSETSDFLSRIKPQECAYDELHTTLPSHGALLGPDDVLAQFLSGDEPLEEPDLNGPTTLHCEICKKRFDNAKKYYGHLRVHSKDNLWVCDQCPDQKFSTKQQLMKHSLTHKPLEREWKCLQCTMAFEALYKLQQHLFAKHLNYKPHNCDQCEKSFTKPSDLEKHKSIHSDVKKHACPECDMRFKDNTNLKRHMLRHNGTKPYCCSGCGTRFKQIASMKRHAQNCALSKCVSEAADTRTRKNHCRVCGMSFQYKSALLEHCVRQHTDAGGAAQNAKPPEPDKDDKSNLNDTNRIVDNIVDDILSAEDDYMTMSTQNEILNVYNPNDIDNNPENLMQIELLKEMNQLHILDGELFYNDIDFDSIQPSHMFNTNTNDMDYTADKNAEILFDFTEGSKSMDQDIMNTLFHVKAEYLPDELLNPPETINAPETNNELDNHNHVSVNECATIFESDVDLEASTNLAANLNQLIGENSVQYISTEDDDTFIISLKSEIDAEQLTDMLNIGVELVNDKTKEPSVPEVKQEIVSLANIELYVKFDKPLSVKEPQNEQLWPVVIKMEEPMTLMATEEKKKVKARKPKKRVLYVCRTCNKAFNKKDNYRSHIATHEPSLRRHKCKICGERFSYRSTLNKHTRSLHTPYVPAEHCCQICDRNFKFAWMLREHMERDHDGLTPHACDYKDCGKSFFKKFDLAVHKRFHTGERPYSCEICKRRFLQASHLRRHEKAVDCTKFISKSESLPSLAQKEKETPTKSTNCDIKIKDELILN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01527643;
90% Identity: iTF_00851053;
80% Identity: -