Basic Information

Insect: Agrotis exclamationis
Gene Symbol: Bcl11a
Assembly: GCA_950005045.1
Location: OX465437.1:15827725-15842340[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0031 0.42 12.6 2.1 2 23 73 94 72 94 0.96

2 12 0.0077 1.1 11.4 0.4 2 23 101 123 100 123 0.94

3 12 1 1.4e+02 4.7 0.2 2 23 131 153 130 153 0.89

4 12 6e-05 0.0082 18.0 2.6 1 23 159 181 159 181 0.97

5 12 3.2e-07 4.4e-05 25.2 2.0 1 23 187 209 187 209 0.96

6 12 0.0054 0.75 11.9 1.2 1 20 215 234 215 236 0.93

7 12 0.69 95 5.2 1.1 3 19 255 271 254 276 0.90

8 12 3.7e-07 5e-05 25.0 1.2 1 23 621 643 621 643 0.98

9 12 1.2e-05 0.0017 20.2 3.9 1 23 650 673 650 673 0.97

10 12 0.0026 0.35 12.9 1.7 3 23 683 704 682 704 0.95

11 12 0.00041 0.057 15.4 3.0 1 23 710 734 710 734 0.98

12 12 0.00043 0.059 15.3 1.1 1 21 740 760 740 761 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0031	0.42	12.6	2.1	2	23	73	94	72	94	0.96
2	12	0.0077	1.1	11.4	0.4	2	23	101	123	100	123	0.94
3	12	1	1.4e+02	4.7	0.2	2	23	131	153	130	153	0.89
4	12	6e-05	0.0082	18.0	2.6	1	23	159	181	159	181	0.97
5	12	3.2e-07	4.4e-05	25.2	2.0	1	23	187	209	187	209	0.96
6	12	0.0054	0.75	11.9	1.2	1	20	215	234	215	236	0.93
7	12	0.69	95	5.2	1.1	3	19	255	271	254	276	0.90
8	12	3.7e-07	5e-05	25.0	1.2	1	23	621	643	621	643	0.98
9	12	1.2e-05	0.0017	20.2	3.9	1	23	650	673	650	673	0.97
10	12	0.0026	0.35	12.9	1.7	3	23	683	704	682	704	0.95
11	12	0.00041	0.057	15.4	3.0	1	23	710	734	710	734	0.98
12	12	0.00043	0.059	15.3	1.1	1	21	740	760	740	761	0.95

Sequence Information

Coding Sequence: ATGGATTCGAATTTACCATTTTTTAGTCTTCCAttCGTGGATTCGGAGACTTCAGACTTTTTGTCTAAGATCAAGCCGCAGGAGTGTGTGTACGATGAATTGCACGCGACTTTACCATCACATGGCGCTTTGTTGGGTCCTGACGATGTCTTGGCTCAATTTTTATCTGGAGATGAACCATTGGAGGAGCCCGACTTAAATGGCCCGACTACGCTGCACTGTGAGATCTGCAAGAAGCGGTTTGATAATGCTAAGAAGTACTATGGACATTTGAGAGTCCATTCCAAGGATAATCTTTGGGTTTGTGATCAATGTCCGGACCAGAAGTTTTCAACGAAGCAGCAGCTGATGAGACATGGCCTGACGCACAAGCCTTTGGGCAGGGAATGGAAGTGCCTGCAGTGCACAATGGCTTTTGAAGCTCTCTGGAAGCTACAGCAGCATCTGTTTGCGAAGCATTTGAACTACAAGCCTCACAAGTGCGATCAATGTGAGAAGTCCTTCACGAAGGCCTCAGACTTGGATAAACATAAATCTATACATAGCGATATGAAAAGACACGCATGTCCTGAATGCGAATTGCGGTTTAAGGACAAGTCAAACTTGAAGCGGCACATGCTGAGACACAGTGGGATCAAGCCTTACTGCTGTTCTGGATGTGGGAGTCGGTTCAAACAGTTGGCTTCCATGAAGCGACACGCGCAGAACTGCTCGTTGAAGAAGGACTCAAGCGATACGGACAAGAGCTCTCGTAAGAACTACTGCCGCGCCTGTGGTATGAGCTTCCAGTACAAGAGCGCTTTGTTGGAGCACTGCGTCAGGCAACATACTACCACAGAAAGTGTTGCGCAACCCGCAAAACCACCGGAACCCGACAAGGAAGATAAGAGCCATCTGAACGACACAAACCGCATCGTAGACAACATAGTGGACGATATTCTATCAGCTGAAGATGACTACATGACCATGCCTACACAGAATGAGATCCTCAATGTTTACAACCCAAATGATATTGATAACAACCCAGAAAATTTAATGCAAATTGAACTTCTAAAGGAAATGAACCAGCTACACATTCTAGATGGAGAACTATTTTACAATGACATAGATTTTGACAGCATACAACCCAGTCACATGTTTAATACTAACACAAACGATATGGATTACAGTATACAGGATAAGAACGCTGAAATTTTATTCGATTTTACTGAAGAAAGCAAAAGTATCGACCAAGATATTATGAACACTCTATTCCATGTGAAAGCTGAGTATTTACCTGATGAACTGCTAAACCCACCAGAAATTCTAAATCCTCCTGATAAAAATAACGAATTAGATAGTCATGTGTCTGTGAATGAATGTGCCACCATATTTGAAAGTGATGTGGATTTAGATGCTAGCACAAATTTAGCTGCAAATTTAAACCAGCTGATTGGTGAAAATAGTGTCCAATACATTTCGACAGAGGACGATGATACATTTATAATAAGTCTGAACAGCGAAATTGATGCTGAACAATTAACAGACATGTTGAATATTGGGGTAGAATTAGTTAATGATAAGACTAAAGAGCCAAGTTTACCTGAAATAAAGCAAGACGCAAGTATACCTGAGATTAAGGAAGAGCCAATTGAACCTGAAAATAAACAAGAACCTGTAAGTTTAGCTAATATAGTGCTATATGTGAAGATTGAAAAGCCTTTACAAGCGAAAGAGACCCAAAATGAGCAGTTAGAAGAACGCTTAATACACAGGCCTATGGTCGTCAAAATTGAAGAACCTATGAGCGAGCCTCCAATGAATTTGATGGCCacggaagagaaaaaagtaataaaGAGGACGCCCAAAAAGAGGGCGATGTATGTTTGCAAAATATGTAATAAGGTGTTCAAGAAGAATGATAATTATAGATCTCATATAgCTACCCACGAGCCGTCTCTCCGTCGCCACAAGTGCAGAGTCTGCGGCGAACGCTTCAGCTACCGCTCGACACTCAACAAGCACACGAGGAGCCTCCACACGCCGTACGTTCAGAAAGAGAACTGCTGCCAGATCTGTGATAGGAACTTCAAGTTCGCGTGGATGTTGAAGGAGCATTTGGAGCGCGACCACGACGGACTAACGCCGTACACGTGCGACTTCAAAGACTGTCGGAAGAGTTTCTTCAAGAAGTCGGACCTCGCTGTCCATAAAAGGTACCACACAGGAGAGCGTCCGTACTCGTGCGAGGTGTGCAAGAAAGCGTTCCTCCACGCGAGCCATCTCCGCAGACACGAGCGTGCTGTCGACTGTACCAAGCAGTGA
Protein Sequence: MDSNLPFFSLPFVDSETSDFLSKIKPQECVYDELHATLPSHGALLGPDDVLAQFLSGDEPLEEPDLNGPTTLHCEICKKRFDNAKKYYGHLRVHSKDNLWVCDQCPDQKFSTKQQLMRHGLTHKPLGREWKCLQCTMAFEALWKLQQHLFAKHLNYKPHKCDQCEKSFTKASDLDKHKSIHSDMKRHACPECELRFKDKSNLKRHMLRHSGIKPYCCSGCGSRFKQLASMKRHAQNCSLKKDSSDTDKSSRKNYCRACGMSFQYKSALLEHCVRQHTTTESVAQPAKPPEPDKEDKSHLNDTNRIVDNIVDDILSAEDDYMTMPTQNEILNVYNPNDIDNNPENLMQIELLKEMNQLHILDGELFYNDIDFDSIQPSHMFNTNTNDMDYSIQDKNAEILFDFTEESKSIDQDIMNTLFHVKAEYLPDELLNPPEILNPPDKNNELDSHVSVNECATIFESDVDLDASTNLAANLNQLIGENSVQYISTEDDDTFIISLNSEIDAEQLTDMLNIGVELVNDKTKEPSLPEIKQDASIPEIKEEPIEPENKQEPVSLANIVLYVKIEKPLQAKETQNEQLEERLIHRPMVVKIEEPMSEPPMNLMATEEKKVIKRTPKKRAMYVCKICNKVFKKNDNYRSHIATHEPSLRRHKCRVCGERFSYRSTLNKHTRSLHTPYVQKENCCQICDRNFKFAWMLKEHLERDHDGLTPYTCDFKDCRKSFFKKSDLAVHKRYHTGERPYSCEVCKKAFLHASHLRRHERAVDCTKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01527643;
90% Identity: iTF_00042028;
80% Identity: -