Etes008943.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eulithis testata
Gene Symbol
-
Assembly
GCA_947507515.1
Location
OX382210.1:4825669-4836872[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 8.5e-05 0.0052 17.4 0.1 3 23 127 147 126 147 0.97
2 16 7.7e-07 4.7e-05 23.8 1.2 1 23 153 175 153 175 0.99
3 16 4.8e-06 0.00029 21.3 2.7 1 23 181 203 181 203 0.99
4 16 3.2e-06 0.00019 21.9 2.6 1 23 218 240 218 240 0.98
5 16 7.6e-05 0.0047 17.5 0.6 1 23 255 277 255 277 0.98
6 16 4.4e-05 0.0027 18.3 3.1 1 23 292 314 292 314 0.98
7 16 2.6 1.6e+02 3.2 0.9 12 23 325 336 324 336 0.92
8 16 0.031 1.9 9.3 1.8 1 23 343 365 343 365 0.98
9 16 5.2e-07 3.1e-05 24.3 2.3 1 23 371 393 371 393 0.99
10 16 0.036 2.2 9.1 1.8 1 23 400 422 400 422 0.98
11 16 2.1e-06 0.00013 22.4 1.5 1 23 428 450 428 450 0.99
12 16 0.0004 0.024 15.3 0.7 1 23 457 479 457 479 0.99
13 16 2.3e-06 0.00014 22.3 1.9 1 23 485 507 485 507 0.98
14 16 0.0017 0.1 13.3 0.3 1 20 513 532 513 535 0.93
15 16 3.3e-05 0.002 18.7 1.4 2 23 542 563 541 563 0.96
16 16 3e-06 0.00018 21.9 1.4 1 23 569 592 569 592 0.97

Sequence Information

Coding Sequence
ATGTTCGAACAGCAAATCAAAGCCGAACCTATGAGTTTCTACCATCCGCACGTATCTCATGTACACCCCGGTCCCCCAACGATAGGGCGTTCCGAGTCGAACCATCATCTCATGAACCCCCATCACCACCAAGAAGACTCTAAAGACAGCCTGATTCAACAACAAGTACAACACCAACAAGATCTCATGGAACAACACCAGCAACAAGAAATGCAGCAAGATGATGAGCTTAGCTTCAAAGGAATGGAAGATGAAGGTGTTGATATGGATATGGACGCCAGACAATGTTCTCAGGGCATGGGAGTGGACATGGGTTCAATACAAACAAAAATGGAGATGAATGGCGGGCAATCTACACCTCGATCAAAACCTCAAGCTTGTAAGGTTTGCGGCAAAGTCCTTTCGTCCGCTTCGTCATATTACGTCCACATGAAGCTTCATTCGGGAAACAAGCCTTTCCAATGCACAGTATGCGATGCAGCTTtttgccgaaaaccatacctggaagttcacatgcgcactcatacaggcgaacgcccgtttcagtgcgatttgtgcctgaagcgatttacacagaaatccagcctcaatacgcacaaacgagtgcacacagatgagcacttgcacgcgttggtggcgaaggaccggccctacaagtgtgagctctgtcagatgcggttcacgcagagttccagcctcaacagacacaagaaaatacacacggAGGAACACAGACGCGCACTGCTGGTCAAGGATCGACCCTACCAATGCGGAATCTGCTTTGTGAGATTCACCCAGAAATCGAGTTTGGGCCGACACGGAAAAATACACACCGAGGAGCACAGACGAGCCCTGTTAGAGAAAGTgcggccgtaccagtgccacatctgttttatgcgcttcactcagaagtccagcctcggacgtcacgggaaaatacacactgAGGAGCACATCCAATCGCTGATCAACAAAaagtcgagcctcaatatacataagaggacgcattcagtccagggcagaccgttccagtgcctgtcgtgccccgccgccttcacctgcaagcaatacctggagattcacacgcgcacgcacaccggcgagcggccgtatcagtgcgacatctgtctgaagcgcttcacgcagaagtccagtctcaacatccacaagcggacgcactcagtgcaagggcgcccgttccagtgcctgcagtgtccggccgccttcacctgcaagcagtacctcgagatccacaaccgcacgcacaccggcgagcggccctaccagtgcgatgtctgcctcaagagattcgcgcaaaagtccacactcaacattcacaaacgaacgcacacagtgcaagggcggccgtaccaatgcatggagtgtccggcggcgttcacttgcaagccgtacttggagattcacatgcgcacgcataccggggaacgtcccttcgagtgcgatgtctgttacaaacgcttcacccagaaatccacgctcaacattcacaagcgaatccacaccgGTGAACGCCCATATGCTTGTGATATCTGCCAGAAACGTTTTGCTGTGAAGAGCTACGTAACAGCCCATAGATGGTCGCACGTCGCCGATAAGCCGTTGAACTGCGATCGGTGTTCGATGACATTTACTTCCAAGTCTCAATTCGCTCTGCACATTCGCACTCACTCTGCTGGGCCGTGCTATGAGTGTAGTGTATGCGGCCGTACTTTTGTTCGAGACAGCTATCTTATACGTCACCACAACCGCGTTCACCGCGAGAACCACAGCAATATGTCTGCGAACATCAACAGCGTCGCTACCAACACCAACAACGGAGGGTTTGACTCCCCCGGTGTCTGCGATCTGAGCTTCGTACCAATGGTGAACCGTTACATGACATCGCAAGGCACGCAAGTATCCATGCAAGACGCCCAGAAGATGTCGGCTATGTCGCCCCAATCTATTGCGTCTATTTCATCGCCCCCTCCCCCGCACACGCCGACCCCCCAACCACAAATGTCGGGTCCCATGCACATGGCAGACTGA
Protein Sequence
MFEQQIKAEPMSFYHPHVSHVHPGPPTIGRSESNHHLMNPHHHQEDSKDSLIQQQVQHQQDLMEQHQQQEMQQDDELSFKGMEDEGVDMDMDARQCSQGMGVDMGSIQTKMEMNGGQSTPRSKPQACKVCGKVLSSASSYYVHMKLHSGNKPFQCTVCDAAFCRKPYLEVHMRTHTGERPFQCDLCLKRFTQKSSLNTHKRVHTDEHLHALVAKDRPYKCELCQMRFTQSSSLNRHKKIHTEEHRRALLVKDRPYQCGICFVRFTQKSSLGRHGKIHTEEHRRALLEKVRPYQCHICFMRFTQKSSLGRHGKIHTEEHIQSLINKKSSLNIHKRTHSVQGRPFQCLSCPAAFTCKQYLEIHTRTHTGERPYQCDICLKRFTQKSSLNIHKRTHSVQGRPFQCLQCPAAFTCKQYLEIHNRTHTGERPYQCDVCLKRFAQKSTLNIHKRTHTVQGRPYQCMECPAAFTCKPYLEIHMRTHTGERPFECDVCYKRFTQKSTLNIHKRIHTGERPYACDICQKRFAVKSYVTAHRWSHVADKPLNCDRCSMTFTSKSQFALHIRTHSAGPCYECSVCGRTFVRDSYLIRHHNRVHRENHSNMSANINSVATNTNNGGFDSPGVCDLSFVPMVNRYMTSQGTQVSMQDAQKMSAMSPQSIASISSPPPPHTPTPQPQMSGPMHMAD