Basic Information

Gene Symbol
-
Assembly
GCA_028551675.1
Location
JAPWLS010000707.1:154017-161999[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 8.4e-05 0.0046 17.3 0.1 3 23 135 155 134 155 0.97
2 16 8.5e-07 4.6e-05 23.6 1.1 1 23 161 183 161 183 0.99
3 16 3.2e-06 0.00017 21.8 3.5 1 23 189 211 189 211 0.99
4 16 1.8e-06 9.6e-05 22.6 3.0 1 23 226 248 226 248 0.99
5 16 4.4e-05 0.0024 18.2 3.1 1 23 263 285 263 285 0.98
6 16 3e-07 1.6e-05 25.0 1.5 1 23 300 322 300 322 0.99
7 16 0.00013 0.0073 16.7 2.8 1 23 328 350 328 350 0.98
8 16 0.031 1.7 9.3 1.8 1 23 357 379 357 379 0.98
9 16 5.1e-07 2.8e-05 24.3 2.3 1 23 385 407 385 407 0.99
10 16 0.036 1.9 9.1 1.8 1 23 414 436 414 436 0.98
11 16 2.1e-06 0.00011 22.4 1.5 1 23 442 464 442 464 0.99
12 16 0.00084 0.046 14.2 0.9 1 23 471 493 471 493 0.99
13 16 3.3e-06 0.00018 21.8 1.8 1 23 499 521 499 521 0.98
14 16 0.0017 0.092 13.2 0.3 1 20 527 546 527 549 0.93
15 16 4.1e-05 0.0022 18.3 1.3 2 23 556 577 555 577 0.96
16 16 3e-06 0.00016 21.9 1.4 1 23 583 606 583 606 0.97

Sequence Information

Coding Sequence
ATGTTTGAGCAGCAGATCAAGGCTGAACCCATGAGTTTTTACACAACCCACCCCCACATGCACACTGGTCCCCCTACGATAGGTCGGTCGGAGTCAGCACACACAATACTAAGTGTGAACCAGCATCATCCAGAGGATTCAAAAGACAGTCTTATAGCACAACATCAGCAGCACCAGCAAATgcttgaacatgagcaacatgaacatgaaatgcagacacacgatcacgagcacgaccatgatcatgatgatTTAAGCTTCAAAGGAATGGATGATGAAGGTGTGGATTTGGATATGGATGCACGACAATGTTCAGAAGGAATGGTGGACATGGGGTCAGTACAAACCAAGATGGAGGTCACGAATGGAGGCACGCAAACACCAAGATCAAAGCCACAAGCTTGTAAGGTTTGTGGAAAAGTCCTCTCATCTGCTTCTTCTTATTATGTTCACATGAAACTTCATTCTGGGAATAAGCCATTTCAATGTTCGGTGTGTGACgcggcattctgcaggaagccgtacctggaagttcacatgcggactcacacaggcgagcggccgttccagtgtgagctctgcttcaagagatttacacagaaatccagtctcaacacgcacaaacgcgtacacaccgATGAGCACATGCGAGCATTGTTGGTGAAGgagcggccgtaccagtgtgagctctgtcagatgcggttcacgcagagttccagcctcaaccgtcacaagaaaacacacaccgAGGAGCACAGACGAGCCCTGTTAGAAAAAGTgcggccgtaccagtgccacatctgttttatgcgcttcactcagaagtccagcctcggcCGACATGGAAAGATTCATACCGAGGAGCACATTCAAGCGCTGATcaacaaagtacgcccatatcaatgcgacatctgtgacaagcggttcacgcagaagtccagccttggcactcataagcgtatacacactggggagaggccgttccagtgcaccgtctgcctcaagtccttcaCACAGAAGTGCGCGCTCAATTTGCACGAAAAGATACATACGGtccagggcagaccgttccagtgcctgtcgtgtcccgccgccttcacctgcaagcagtacctggagatacacacgcgaactcacaccggcgagcgtccctaccagtgcgacatctgcctcaaacgcttcacgcagaagtccagcctcaacatccacaagcgaacgcactcagtacagggacggcccttccagtgtctgcaatgtcctgcagccttcacctgcaagcagtatctggagattcataaccgaacgcacacaggcgagcgcccttaccagtgcgacgtgtgcctcaagaggttcgcacaaaagtcgacgctcaacattcacaagaggacgcatacggtgcaaggtcgcccgtaccagtgctcggagtgtccggccgcgttcacctgcaaaccgtacctggagatacacacgcgcactcacactggcgagcgacccttccaatgcgacgtctgtctcaaacgcttcacacagaaatccacactgaacattcacaagcgaatacataccgGTGAACGTCCATACGCATGTGATATATGTCAGAAGAGGTTTGCTGTGAAGAGTTATGTCACAGCGCACAGATGGTCTCACGTGGCAGACAAACCTTTGAATTGTGATCGATGCTCGTTAACTTTTACGTCGAAGTCTCAGTTCGCCCTCCATATCCGCACGCACTCTGCCGCATCATGCTATGAATGTAGTGTTTGCGGACGCACGTTTGTCAGGGACAGCTATCTTATAAGACACCACAATCGTGTGCATCGTGATAATCATAGTAATATGTCAGCGAACAGTATGTCCAATATTAACAGTGTTGCAACAAACACGAGCTCTGTTAATGCCAATTACGACTCACCAGGGGTCTGCGATCTCAGTTTTGTGCCAATGGTGAATAGATATATGACGTCACAAGGCACGCAAGTCTCAATGCAGGACACATCGAGCAAGATGTCGGCGATGTCACCACAATCAATTGCGTCAATATCATCGCCGCCGCCGCCGCACACTCCCACGCCGCAGCCAATGTCGGGGCAGATGCACCTCTCTGACTGA
Protein Sequence
MFEQQIKAEPMSFYTTHPHMHTGPPTIGRSESAHTILSVNQHHPEDSKDSLIAQHQQHQQMLEHEQHEHEMQTHDHEHDHDHDDLSFKGMDDEGVDLDMDARQCSEGMVDMGSVQTKMEVTNGGTQTPRSKPQACKVCGKVLSSASSYYVHMKLHSGNKPFQCSVCDAAFCRKPYLEVHMRTHTGERPFQCELCFKRFTQKSSLNTHKRVHTDEHMRALLVKERPYQCELCQMRFTQSSSLNRHKKTHTEEHRRALLEKVRPYQCHICFMRFTQKSSLGRHGKIHTEEHIQALINKVRPYQCDICDKRFTQKSSLGTHKRIHTGERPFQCTVCLKSFTQKCALNLHEKIHTVQGRPFQCLSCPAAFTCKQYLEIHTRTHTGERPYQCDICLKRFTQKSSLNIHKRTHSVQGRPFQCLQCPAAFTCKQYLEIHNRTHTGERPYQCDVCLKRFAQKSTLNIHKRTHTVQGRPYQCSECPAAFTCKPYLEIHTRTHTGERPFQCDVCLKRFTQKSTLNIHKRIHTGERPYACDICQKRFAVKSYVTAHRWSHVADKPLNCDRCSLTFTSKSQFALHIRTHSAASCYECSVCGRTFVRDSYLIRHHNRVHRDNHSNMSANSMSNINSVATNTSSVNANYDSPGVCDLSFVPMVNRYMTSQGTQVSMQDTSSKMSAMSPQSIASISSPPPPHTPTPQPMSGQMHLSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00686557;
90% Identity
iTF_01452554;
80% Identity
-