Dpar007789.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila parthenogenetica
Gene Symbol
su(Hw)
Assembly
GCA_035047505.1
Location
JAWNPM010000159.1:2655723-2659674[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00069 0.052 14.2 2.2 1 20 256 275 256 277 0.94
2 12 2.9e-06 0.00021 21.7 0.4 3 23 328 349 326 349 0.93
3 12 0.02 1.5 9.6 0.1 1 23 355 377 355 377 0.95
4 12 7.8e-07 5.8e-05 23.5 2.5 1 21 384 404 384 405 0.95
5 12 3.4e-06 0.00025 21.5 0.6 2 23 417 438 416 438 0.96
6 12 0.00011 0.0081 16.7 5.3 1 23 449 471 449 471 0.99
7 12 8.4e-05 0.0063 17.1 0.9 1 23 477 499 477 499 0.97
8 12 1.7e-05 0.0013 19.3 0.8 1 23 505 527 505 527 0.99
9 12 1.5e-06 0.00012 22.5 3.0 1 23 533 555 533 555 0.98
10 12 0.00058 0.044 14.4 2.7 1 23 559 581 559 581 0.95
11 12 3.3e-05 0.0024 18.4 0.1 1 20 589 608 589 613 0.92
12 12 9.3e-05 0.007 16.9 0.3 3 23 633 654 631 654 0.96

Sequence Information

Coding Sequence
ATGTTTACGAGAATTGTGAATTGTCAGACGCCAACGCCATTGTGTACGCGTTACGTGCCAGCGCTCGTGGTTCAAACTAGTCCTTTGCACAATATTCTGGCAATGAGCGTCAACAAGGAGCGCAAAGTGACGGACGTCACCGCCTCCAGTAACAATGATGTCGGGACTGTGATCAAAATACTAGACGTCGCACAGATCGTgtcacaaaaagaaaaacggcCCAGCACACGCATGAAGCTACTCAACGATGTCACAGCCAAAAGTGTCAGCAAGAGCCCCTCGAACTCAGCGCGTGTGAAGCAGGAGAAGCGCGCGAGCATTAAGATACTTAACAACGATGAGACGACTACCAGTTCTCCCAAGGGTGACAAACGCGCTGCCGCCAAAACCGTCAGTCCCACGGCCAGTGTTAAGATATTGAACGAGAAGCGTTCGTCAACGGCTGCTACACCTGTGGAAACGGCCAAGATTAAGACGTCGCccagcaaaaagaagaaaatggaTCACTATGTGCTGCAAGCCATCAAGAGTGAGAATAGTAAAGCGGACAATACATCCACCTCCATTGTGGTTGAGGATGAGGACACAATTGACTTTATTCTGGCCGAGAACGATGACATTGATCTGGGTGCAGCCAAGGCTAATGACGATGAGTTCGTTGTCTCGGGCGTGGAGGAAgatgacgacgatgaggaCGAGGCTCTGGGTGAGGGAAGCCCTAATCGCGCTAGTGGCACCAACAGCGACCTCAAGGAAATGGTAGAGCACGTGTGCGGCAAGTGCTACAAGACATTCCGACGCGTCAAAAGTCTGAAGAAACACTTGGAATTCTGTCGCTACGACAGTGGCTATCATCTGCGCAAGGCGGACATGCTCAAGAACCTGGAGAAGATCGAGCGAGATGCGGTGGTCATGGAGAAGAAAGACATATGCTTCTGCTGCAGCGAGAGCTACGACACCTTTCATCTGGGTCACATCAATTGTCCGGATTGTCCCAAATCTTTCAAGACACAGACGAGCTATGAGCGTCACATATTCATCACTCACTCTGAGCTCAATGATTACCCCTGCTCGATTTGCAATGCTAAGCTTCGCAGTGCTGCGCTGCTGAAGCTTCACGAGGAGCAGCATCAGTCACGTGGCAAACCCTTCGCCTGCAAGATCTGCGGCAAGGACTTTACACGCTCCTATCATCTAAAGCGGCATCAAAAGTACTCCTCGTGCTCGGCCAATGAGAATGATACCATGAGCTGCAAGGTGTGCGATCGTGTTTTCTATCGTCTGGACAACTTGAGGGCTCATCTCAAGCAGCATTTGGGCACACAGGTGGTCAAGAAGCCGGAATACATGTGCCATGTGTGCAAGAACTGTTTCTACAGTCTGTCCACTTTGAACATTcacattcgcacacacacggGTGAGAAACCCTTCGACTGCGATCTGTGCGATAAGAAGTTCTCCGCCTTGGTGGCCCTCAAGAAGCATCGTCGTTATCACACAGGCGAGAAGCCCTACACCTGCACAGTGTGCAGTCAATCGTTTGCCGTCAAAGAGGTGCTCAATCGCCACATGAAGCGTCACACGGGCGAGCGTCCACACAAGTGCAACGAGTGCGGCAAAAGCTTCATTCAAGCCACTCAGCTACGTACTCATTCCAAGACGCATCTGCGTCCACACGCCTGTTCGCTGTGCACCCAAAAGTTTAAGACAGAGAAACAACTTGAGCGCCACGTTAAGGAGCATACACGCCAAAAGCGTGCCAGCTTCGCCTGTCCTGACTGCCCTCGCAGTTTCCGCACCACTGTACAGCTCAAGGAGCACATTGATGCCGGTGATCATTCGCCTGTTAAAACGACACGGGCCAAGCGCACGGCGAAGGTAATTGAACGCACGGATTGTGCCATTTGTGACAAGAACTTTGATAGCACAGAAACATTGAGGAATCACATACGCAATGTCCACGAATGTGATCCCGATGATATCTTTGGTACTGGGCCACCAGCCAAGCGTCGAGCCAAAAAGGCCATTGTGATAGCGGATGAGGTGGaagatgatgacgacgacgctGACGAAGATGGCGAGGAGGCTGAAGAGGGAGAAGAAGAGGAGGCCGAGGAAGTATTGCCAAATACTTCAGCAGGTTCCCTAATCTCCAGCAAAACCGATGACAATGGCGTTGTAGTGCGTGAATTTTTGGTGGACGAGGGCGATGGTAACGCCCAGACAATAATGCTGGAGAACGAAGTCTATACAATTCTGCCCTTGGAGGGTAGCAATACCACAGAAGCCGCAACGTCCGGCAAGAGCGTCAAGCCCGAGTCTAAAGACAAGGACAAACAATCAAAGGTTGTGTCACCGGTGGTGAAGAAAGAGCAGCGCAAATCTCTTGCTGCCAGCTTGGCAGCTGCCATTGCTGATAATCTGGAGGAGCAAGTCAGCGAAGATGATTTCGCTGGCGAAGTGCTGACCGAAGAGGATATAAAGCTTAAGGAGAACATTGCCAAGTTGATTGATATGCTCGTTGATCCGCAGACTCTTAAGAAATATGGCTGGCCCAACAGCTCCGTGGAGACGGTGCTGTGCAAGGTGATTGAGAACTGTGGCCACGATCTGGCCAAGGGAGGCGAGAACTACGCCGAATTGGACTATGGCAGTCGCATGCGTGAATACTGTAAACTGCTGTTCACTGTTGTCATACACAACGATTCGATCAAGTCGCTGTTGAATAACTTTCCCATTGACGATGTCATCGAGTATGTGCTGGGCGATGAGGATCAGGACCAGGAACTAGAGCTTGGCAAAGGCGACGAGAAGCAAAACGAGAAGTCCGATACGGAAACCACACAACTAGATGCGGTTGAAGCCGAGGCATGA
Protein Sequence
MFTRIVNCQTPTPLCTRYVPALVVQTSPLHNILAMSVNKERKVTDVTASSNNDVGTVIKILDVAQIVSQKEKRPSTRMKLLNDVTAKSVSKSPSNSARVKQEKRASIKILNNDETTTSSPKGDKRAAAKTVSPTASVKILNEKRSSTAATPVETAKIKTSPSKKKKMDHYVLQAIKSENSKADNTSTSIVVEDEDTIDFILAENDDIDLGAAKANDDEFVVSGVEEDDDDEDEALGEGSPNRASGTNSDLKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIERDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSELNDYPCSICNAKLRSAALLKLHEEQHQSRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPHACSLCTQKFKTEKQLERHVKEHTRQKRASFACPDCPRSFRTTVQLKEHIDAGDHSPVKTTRAKRTAKVIERTDCAICDKNFDSTETLRNHIRNVHECDPDDIFGTGPPAKRRAKKAIVIADEVEDDDDDADEDGEEAEEGEEEEAEEVLPNTSAGSLISSKTDDNGVVVREFLVDEGDGNAQTIMLENEVYTILPLEGSNTTEAATSGKSVKPESKDKDKQSKVVSPVVKKEQRKSLAASLAAAIADNLEEQVSEDDFAGEVLTEEDIKLKENIAKLIDMLVDPQTLKKYGWPNSSVETVLCKVIENCGHDLAKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQDQELELGKGDEKQNEKSDTETTQLDAVEAEA