Basic Information

Insect: Drosophila innubila
Gene Symbol: su(Hw)_1
Assembly: GCA_004354385.1
Location: NW:10466857-10471510[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00057 0.032 14.3 2.2 1 20 228 247 228 249 0.94

2 12 2.4e-06 0.00013 21.8 0.4 3 23 300 321 298 321 0.93

3 12 0.022 1.2 9.3 0.1 1 23 327 349 327 349 0.95

4 12 6.5e-07 3.6e-05 23.5 2.5 1 21 356 376 356 377 0.95

5 12 2.8e-06 0.00016 21.5 0.6 2 23 389 410 388 410 0.96

6 12 9e-05 0.0051 16.8 5.3 1 23 421 443 421 443 0.99

7 12 7e-05 0.0039 17.1 0.9 1 23 449 471 449 471 0.97

8 12 5.3e-06 0.0003 20.7 0.8 1 23 477 499 477 499 0.99

9 12 3.9e-07 2.2e-05 24.2 2.1 1 23 505 527 505 527 0.98

10 12 0.00044 0.025 14.6 2.5 1 23 531 553 531 553 0.97

11 12 0.00041 0.023 14.7 0.1 3 20 563 580 561 585 0.92

12 12 7.7e-05 0.0044 17.0 0.3 3 23 605 626 603 626 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00057	0.032	14.3	2.2	1	20	228	247	228	249	0.94
2	12	2.4e-06	0.00013	21.8	0.4	3	23	300	321	298	321	0.93
3	12	0.022	1.2	9.3	0.1	1	23	327	349	327	349	0.95
4	12	6.5e-07	3.6e-05	23.5	2.5	1	21	356	376	356	377	0.95
5	12	2.8e-06	0.00016	21.5	0.6	2	23	389	410	388	410	0.96
6	12	9e-05	0.0051	16.8	5.3	1	23	421	443	421	443	0.99
7	12	7e-05	0.0039	17.1	0.9	1	23	449	471	449	471	0.97
8	12	5.3e-06	0.0003	20.7	0.8	1	23	477	499	477	499	0.99
9	12	3.9e-07	2.2e-05	24.2	2.1	1	23	505	527	505	527	0.98
10	12	0.00044	0.025	14.6	2.5	1	23	531	553	531	553	0.97
11	12	0.00041	0.023	14.7	0.1	3	20	563	580	561	585	0.92
12	12	7.7e-05	0.0044	17.0	0.3	3	23	605	626	603	626	0.96

Sequence Information

Coding Sequence: ATGAGCACCAACAAGGAGGCCAAAATGACTGACGCCCCTAAGGCAACCGTCGTCTCTGTTCCTGTTCCCAGTGGCAATGATGAAACTGTCGTCAAAATACTGGACGCTGGCCAAGTCGTAGCTGCCAAGGAGAAGCGACCCAGTACTCGCATGAAACTGCTCAATGATGCGGCAGCCAAAGGCGGAAGCAAGGCCGCATCAGTCTCCACGCCCCGTGTTAAGCAGGAGAAGCGCACAAGCATCAAAATACTGAACAATGATGAAGCCACAAGCACTCCCAAAGGCGACAAACGATCCACAACAAAAACTGTAAGTCCCACCGGAAGTGTCAAGATATTAAACGAGAAGCGCACTGCGGTGGTTGCCACCCCGGTGGAAACGACCAAGATCAAAACATCGCCcagcaaaaagaagaaaatggATCACTATGTACTGCAGGCCATTAAAAGCGAGAGCAGTAAGGCGGACAACACCACCAGCATTGTGATCGAGGATGAGGATACTATTGACTTTATACTTGCCGAGAATGATGACATTGAGCTGGGAGCAGCCAAAGCAAATGACGATGAGTTTGTTGTCTCCGGCGTTGAGGAAGATGACGACGATGAGGACGATGTATTGGGTGAAGGCAGTCCTAACCGCAAAAGTGGCAACAATAGCGACCTCAAGGAAATGGTGGAGCACGTGTGCGGCAAGTGCTATAAGACATTCCGACGCGTTAAGAGCCTCAAGAAGCACCTGGAATTCTGTCGCTATGACAGTGGCTATCATCTGCGCAAGGCGGACATGCTTAAGAATCTGGATAAAATCGAAAAGGATGCTGTGGTCATGGAGAAGAAAGACATCTGCTTCTGCTGCAGCGAGAGCTACGACACTTTTCATCTTGGCCACATCAATTGTCCAGACTGTCCCAAGTCGTTTAAGACCCAGACCAGCTATGAGCGTCACATCTTCATCACTCACTCCGAGCTCAATGATTTCCCCTGCTCCATTTGCAATGCGAAGCTGCGCAGCGCTGCCCTGTTGAAGTTGCATGAGGAGCAGCATCAGTCGCGTGGCAAGCCATTCGCATGCAAGATCTGTGGCAAGGACTTTACTCGCTCCTACCATCTAAAGCGCCATCAAAAGTACTCCTCGTGCTCGGCCAACGAAAATGATACCATGAGCTGCAAGGTGTGCGATCGTGTCTTCTATCGCCTGGACAATTTGCGGGCCCATCTCAAGCAGCACTTGGGCACTCAGGTGGTGAAGAAGCCGGAATACATGTGCCATGTGTGCAAGAACTGCTTCTACAGTCTCTCTACGCTCAACATTCATATACGCACTCACACTGGTGAGAAACCATTCGACTGCGATCTGTGTGACAAGAAGTTCTCAGCCTTGGTGGCACTCAAGAAGCATCGTCGTTATCATACGGGCGAGAAACCCTACACTTGCACAGTGTGCAATCAATCGTTTGCCGTCAAAGAGGTGCTCAATCGCCACATGAAGCGACACACTGGCGAGCGTCCACACAAGTGTCCCGAGTGCGGCAAGAGCTTCATCCAAGCGACACAGCTACGTACGCATTCCAAGACGCATCTGCGTCCCTTTCCCTGCTCCTCGTGCACCCAAAAATTTAAGACAGAGAAACAACTTGAGCGCCACTTTAGGGAGCATACACGTCAGAAGCGTCTCGGCTTTGGCTGCTTGGATTGTCCACGTAGTTTCCGCACCAGCGCATTGCTCAAGGAGCACATTGATGCGGGCGATCATTCGCCTGTGAAACCAACTCGGGCCAAGCGCACTGCCAAGATGATCGAGCGCACGGACTGCGCCATCTGTGACAAGAACTTTGATAGCACCGAAACCCTGCGAAATCATATACGCAACGTGCACGAATGCGATCCGGATGATATCTTTGGCACAGGGCCACCTGCTAAACGTAAAGCTAAAAAGACCATTGTGGTGGAGGAGGAAGTGGAAGATGATGAGGAAGTGGAGGAGGCGGATGAGGAAGTGGCACCAGCAAACACATCGGCAGGCTCGCTCATCTCCAGCAAAACCGATGGCAATGGCGTTGTGGTTCGTGAGTTCCTGGTGGATGAGGGAGATGGAAGTGCACAGACCATTATGCTAGAGAATGAAGTCTACACCATTTTGCCTTTGGAGGGAGCCAGCGCGACCGAGGCACCTGCTGTAAGTGAGGTCAAGTCCGACTCTAAGGAGAAGCAGTCCCCGGCTGTCTCACCGGTTGTCAAGAAGGAGCAGCGCAAATCCCTGGCTGCTAGCTTGGCAGCTGCCATTGCTGATAATCTGGAGGAGCCATCAAGCGAGGATGAGTTCACCGGCGAGGTGCTCACCGAAGCGGATCTGAAACTCAAGGAGAACATTGGAAAGTTGATCGACATGCTCGTCGATCCGCAAACACTTAAGAAATACGATTGGCCAAATAGCTCCGAGGAGACTGTACTGTGCAAGGTCATCGAGAACTGTGGCCACGATCTGGCCAAGGGAGGAGAGAGCTATGCCGAGTTGGATTACGGCAGCCGCATGCGCGAATATGTCAAGCTCCTGTTCACAGTTGTCATTCATAATGATTCGATCAAGGCGCTGCTAAATAACTTCCCAATTGACGAGGTTATTGAGTATGTGCTGGGTGATGAAGATCAGGACGAGGATCTGGTATTGGGTGAAGATCAGGAGCCTGATAAGTCCGATAAGGAGAAGAGACTGGATGCCGTTGAAGCTGAGGCTTGA
Protein Sequence: MSTNKEAKMTDAPKATVVSVPVPSGNDETVVKILDAGQVVAAKEKRPSTRMKLLNDAAAKGGSKAASVSTPRVKQEKRTSIKILNNDEATSTPKGDKRSTTKTVSPTGSVKILNEKRTAVVATPVETTKIKTSPSKKKKMDHYVLQAIKSESSKADNTTSIVIEDEDTIDFILAENDDIELGAAKANDDEFVVSGVEEDDDDEDDVLGEGSPNRKSGNNSDLKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLDKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSELNDFPCSICNAKLRSAALLKLHEEQHQSRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCNQSFAVKEVLNRHMKRHTGERPHKCPECGKSFIQATQLRTHSKTHLRPFPCSSCTQKFKTEKQLERHFREHTRQKRLGFGCLDCPRSFRTSALLKEHIDAGDHSPVKPTRAKRTAKMIERTDCAICDKNFDSTETLRNHIRNVHECDPDDIFGTGPPAKRKAKKTIVVEEEVEDDEEVEEADEEVAPANTSAGSLISSKTDGNGVVVREFLVDEGDGSAQTIMLENEVYTILPLEGASATEAPAVSEVKSDSKEKQSPAVSPVVKKEQRKSLAASLAAAIADNLEEPSSEDEFTGEVLTEADLKLKENIGKLIDMLVDPQTLKKYDWPNSSEETVLCKVIENCGHDLAKGGESYAELDYGSRMREYVKLLFTVVIHNDSIKALLNNFPIDEVIEYVLGDEDQDEDLVLGEDQEPDKSDKEKRLDAVEAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00569117;
90% Identity: iTF_00510679;
80% Identity: -