Dfor005380.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila formosana
Gene Symbol
su(Hw)
Assembly
GCA_035045625.1
Location
JAWNOW010000272.1:4869405-4873422[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00067 0.043 14.2 2.2 1 20 241 260 241 262 0.94
2 12 2.8e-06 0.00018 21.7 0.4 3 23 313 334 311 334 0.93
3 12 0.019 1.3 9.6 0.1 1 23 340 362 340 362 0.95
4 12 5.5e-07 3.5e-05 24.0 2.4 1 21 369 389 369 390 0.95
5 12 3.3e-06 0.00021 21.5 0.6 2 23 402 423 401 423 0.96
6 12 0.0001 0.0068 16.8 5.3 1 23 434 456 434 456 0.99
7 12 8.1e-05 0.0052 17.1 0.9 1 23 462 484 462 484 0.97
8 12 1.6e-05 0.0011 19.3 0.8 1 23 490 512 490 512 0.99
9 12 4.5e-07 2.9e-05 24.2 2.1 1 23 518 540 518 540 0.98
10 12 0.0021 0.13 12.7 3.3 1 23 544 566 544 566 0.96
11 12 3e-05 0.002 18.5 0.2 1 20 574 593 574 598 0.93
12 12 9e-05 0.0058 17.0 0.3 3 23 618 639 616 639 0.96

Sequence Information

Coding Sequence
ATGGTTAGACGCCAACGCCATTGTGTTCGCGTTACGTGCCAGCGCTCGTGGTTCAAATTGCAAACTCCTGCGAGCCGATTGCACATTCAACCCATCAACAACATGGCTGACGCTGGAACAGTGATCAAGATTCTCGATGTCTCACAAATCGCATCGCCCAAGGACAAAACGAGGCCCGGAAATCGGATGAAGCTGCTCAACGATGTGCCAGCGAAGGGCAACAAAAAGGCTACCTCCGTTTCGCCGCGTGTCAAGCAGGAGAAGCGAGCGAGCATCAAAATACTGAACACGGATGAGACGACCCAAAAGAGCGACAAGCGATCATCGGCCACCAAAACTGTGAGTCCCACGGGCAGCGTCAAGATCCTGAACGAGAAGCGAGCCGCGGTCGCAACGACGCCTGTGGAGACGACCAAGATCAAGACGTCGCCGagtaaaaagaagaaaatggATCATTATGTGCTGCAGGCCATCAAGAGtgagaacagcagcagcaaggcgGACAACACACCAAACAGCAGCGTGGTGGTGGATGAGGAGGATACCATTGACTTTATACTCGCGGAGAACGATGAAATCGAGCTGGCGGCAGCCAAGGCAAACGATGAAGAGTTTGTGGTGTCGGGCATTgaggaggacgacgatgaAGACGAGGACGCCTTGGTGGAGGGCGGCTCGAATCGCACCAGTGGCAACAGCGAACTGAAGGAGATGGTGGAGCATGTGTGCGGCAAGTGCTACAAGACATTCCGACGGGTCAAGAGCCTCAAGAAGCACTTGGAGTTCTGTCGCTACGACAGCGGCTATCATCTGCGCAAAGCGGACATGCTCAAGAACCTCGAGAAGATCGAGCGCGATGCGGTGGTCATGGAGAAGAAAGATATTTGCTTCTGCTGCAGCGAGAGCTACGACACCTTCCATCTGGGTCACATCAATTGCCCCGATTGCCCCAAGTCGTTTAAGACCCAGACCAGCTACGAGCGTCACATTTTCATAACTCACTCCGAGCTTAACGATTATCCTTGTTCCATTTGCAATGCCAAGCTGCGCAGCGCGGCTCTATTGAAGCTGCACGAGGAGCAGCATCAGTCGCGTGGCAAGCCGTACGCCTGCAAGATCTGTGGCAAGGACTTTACGCGTTCGTATCACCTGAAGCGGCATCAGAAGTACTCGTCGTGTTCGGCCAATGAGAACGACACCATGAGCTGTAAGGTGTGCGATCGCGTCTTCTATCGTCTGGACAATTTGCGTGCGCATCTCAAACAGCATTTGGGCACACAGGTGGTCAAGAAGCCGGAATATATGTGCCATGTGTGCAAGAACTGCTTCTACAGCCTCTCCACGCTGAATATTCACATTCGTACGCACACAGGCGAGAAGCCCTTTGACTGCGATCTGTGCGACAAAAAGTTCTCCGCCTTAGTGGCACTCAAGAAGCATCGTCGCTATCACACCGGCGAGAAGCCCTACACCTGCACAGTGTGCAGTCAATCATTTGCCGTCAAGGAGGTGCTGAATCGCCACATGAAACGGCACACGGGCGAGCGTCCGCATAAGTGTCCCGAGTGCGGCAAGAGCTTCATACAGGCCACTCAGCTGCGCACGCATTCCAAGACGCATCTGCGTCCCCATTCCTGCTCCTTGTGCAACCAAAAGTTCAAAACGGAGAAGCAGCTGGATCGCCATGCTAAGGAGCACACGCGTTCCAAGCGTGCGTCATTCCCTTGCACAGACTGCTCGCGCAGCTTCCGCACCAGCGCACAGCTAAAGGAGCACGTGGATGCCGGCGATCATTCACCTGTAAAAGCAACGCGTGCCAAGCGCACGGTCAAGATGATCGAGCGGACGGACTGTGCCATCTGCGACAAGAACTTCGACAGCACCGAAACACTGAGGAACCACATACGCAACGTGCACGAATGCGATCCGGATGACATCTTTGGCACAGAGCCACCCACCAAGCGAAAGGCTACCAATAAAAAGACAATTGTGTTGGACGATGATGAGGAGGAGAATGAAGATATGGCGCAAGCCAACACATCGGCTGGGTCGCTCATCTCGAGCAAAACAGACGACAATGGCGTTGTTGTGCGTGAGTTCCTGGTAGATGAGGGGGATGGCAATGCACAGACCATTCTGCTGGAGAACGAAGTATACACCATTCTGCCCTTGGATGGTGGCTCAGAGACACCAGCAGCCACAAGCAGCGATGTCAAAGACAACAGTGTGAAGGAGAAGGCGTCATCGGAAGTGTCGCCAGTCGTGAAGAAGGAGCAGCGCAAGTCGTTGGCTGCCAGCTTGGCAGCTGCTATTGCCGATAACACTGAGGAGCCGTCGAGCGATGATGAATTCACCGGCGAGGTGCTCACCGAAGAGGATCTTAAGCTGAAGGAGAATATTGCCAAGTTGATCGACATGTTGGTCGATCCGCAAACACTCAAGAAGTACAACTGGCCGAACAGCTCCGAGGAGACGGTACTGTGCAAGGTCATCGAGAATTGTGGCCACGATCTGGCCAAGGGAGGCGAGAACTACGCCGAACTAGACTACGGCAGTCGCATGCGCGAATATTGCAAACTGCTCTTCACAGTCGTCATACACAACGATTCGATCAAGTCTCTGTTGAACAATTTCCCCATTGACGATGTCATTGAGTATGTGCTGGGCGATGAGGATCAGGATCAAGACATGGCCAAGGGCGACGAGAAAGAGGGGGCCGAAAAGTCAAATGCGGGCACAGATGCGGAGGACACTTTGGCAATCGTGGAAGCCGAGGCTTAA
Protein Sequence
MVRRQRHCVRVTCQRSWFKLQTPASRLHIQPINNMADAGTVIKILDVSQIASPKDKTRPGNRMKLLNDVPAKGNKKATSVSPRVKQEKRASIKILNTDETTQKSDKRSSATKTVSPTGSVKILNEKRAAVATTPVETTKIKTSPSKKKKMDHYVLQAIKSENSSSKADNTPNSSVVVDEEDTIDFILAENDEIELAAAKANDEEFVVSGIEEDDDEDEDALVEGGSNRTSGNSELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIERDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSELNDYPCSICNAKLRSAALLKLHEEQHQSRGKPYACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCPECGKSFIQATQLRTHSKTHLRPHSCSLCNQKFKTEKQLDRHAKEHTRSKRASFPCTDCSRSFRTSAQLKEHVDAGDHSPVKATRAKRTVKMIERTDCAICDKNFDSTETLRNHIRNVHECDPDDIFGTEPPTKRKATNKKTIVLDDDEEENEDMAQANTSAGSLISSKTDDNGVVVREFLVDEGDGNAQTILLENEVYTILPLDGGSETPAATSSDVKDNSVKEKASSEVSPVVKKEQRKSLAASLAAAIADNTEEPSSDDEFTGEVLTEEDLKLKENIAKLIDMLVDPQTLKKYNWPNSSEETVLCKVIENCGHDLAKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQDQDMAKGDEKEGAEKSNAGTDAEDTLAIVEAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00569117;
90% Identity
iTF_00614318; iTF_00520763; iTF_00589670; iTF_00595376;
80% Identity
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