Dtri002249.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila tripunctata
Gene Symbol
su(Hw)
Assembly
GCA_035047385.1
Location
JAWNPS010000100.1:422520-425710[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0007 0.047 14.2 2.2 1 20 237 256 237 258 0.94
2 12 2.9e-06 0.0002 21.7 0.4 3 23 309 330 307 330 0.93
3 12 0.02 1.4 9.6 0.1 1 23 336 358 336 358 0.95
4 12 7.9e-07 5.3e-05 23.5 2.5 1 21 365 385 365 386 0.95
5 12 3.4e-06 0.00023 21.5 0.6 2 23 398 419 397 419 0.96
6 12 0.00011 0.0074 16.7 5.3 1 23 430 452 430 452 0.99
7 12 8.5e-05 0.0058 17.1 0.9 1 23 458 480 458 480 0.97
8 12 1.7e-05 0.0012 19.3 0.8 1 23 486 508 486 508 0.99
9 12 2.6e-06 0.00018 21.8 2.2 1 23 514 536 514 536 0.98
10 12 0.00013 0.0085 16.6 2.1 1 23 540 562 540 562 0.97
11 12 0.00015 0.01 16.3 0.1 1 21 570 590 570 594 0.91
12 12 9.4e-05 0.0064 17.0 0.3 3 23 614 635 612 635 0.96

Sequence Information

Coding Sequence
ATGAGCGCCAACAAGGAAAAACTGAAGGAGAAAGAGAAGGAGGCCAAAACGAACTCTGACCTCCCAGGCGGTACAGTGATCAAAATACTGGATGTGGCACAAATCGTGTCCCCTGGCAAGGAAAAGCGTCCCAGTACTCGCATGAAACTGCTCAACGATGTGGCAGCAAACAAAGCATCATCTGCCACGCCGCGTGTCAAGCAAGAGAAACGCACAAGCatcaaaatacttaataaCAATGAAGAAACTGCTCCTACTCCCTCCAAGGGCGACAAACGATCTTCCACTAAAACCGTAAGTCCCACTGGCAGTGTCAAGATATTGAATGAGAAGCGTGCCGCTTCCTCGGCGGCTGCCACACCCGTCGAAATggccaaaatcaaaacatcgcctagcaaaaagaagaaaatggATCACTATGTGCTGCAGGCCATAAAGAGCGAGTCGAGCAAAGCAGACAACACATCCAtatccatgtccatgtccacaTCCACATCTGTAGTAGTGGAAGATGAGGATACTATTGATTTTATACTCGCGGAGAACGATGATATTGAACTGGGAGCAGCTAAGGCAAACGATGATGAGTTTGTTGTCTCTGGCATTGAGgaggatgacgatgatgaggatgatgatgaagctTTGGCCGATGCAAGTCCCAATCGCACAAATGCCAGCAATAGTGGCGAACTCAAGGAAATGGTTGAACAcgtgtgtggcaagtgctACAAGACATTCCGTCGCGTGAAGAGCCTCAAGAAACACTTGGAGTTCTGCCGCTACGACAGTGGCTATCATTTGCGCAAAGCGGACATGCTCAAGAATCTGGACAAGATCGAGCGAGATGCTGTGGTCATGGAGAAGAAAGACATTTGCTTCTGCTGCAGCGAGAGTTACGATACCTTTCATCTTGGCCACATCAACTGCCCGGACTGTCCCAAGTCATTCAAGACACAAACTAGCTATGAGCGTCACATCTTCATCACACACTCTGAGCTCAACGATTATCCCTGCTCTATTTGCAATGCCAAGCTACGCAGTGCTGCTCTCTTGAAGCTGCACGAGGAGCAGCATCAGTCGCGTGGCAAACCCTTTGCTTGCAAAATCTGTGGCAAGGATTTTACACGCTCATACCATTTGAAGCGTCATCAAAAGTATTCATCGTGCTCGGCCAATGAGAACGATACCATGAGCTGCAAGGTGTGCGATCGTGTCTTCTATCGTTTGGACAATCTGCGAGCGCATCTTAAGCAGCATTTGGGCACTCAGGTGGTCAAGAAACCGGAATATATGTGCCATGTCTGCAAGAACTGTTTCTACAGTCTCTCCACATTGAACATTCACATACGCACTCACACCGGCGAGAAACCCTTCGATTGTGATCTGTGCGACAAGAAATTTTCAGCTCTGGTGGCACTCAAGAAGCATCGTCGTTATCATACGGGCGAGAAGCCCTACACTTGCACAGTGTGCAGTCAATCGTTTGCCGTCAAGGAGGTGCTCAATCGTCACATGAAGCGACACACGGGCGAACGTCCGCACAAGTGCGGCGAGTGCGGCAAGAGCTTCATACAGGCCACCCAGCTGCGTACGCATTCCAAGACGCATCTGCGTCCCTTCTCCTGCTCGTTGTGCACCCAGAAGTTTAAGACAGAGAAACAACTTGAGCGTCACGTTAAGGAGCACACACGCCAGAAGCGTCCCTGCTTTGCATGCTTGGAATGCTCTCGGAGTTTTCGCACCAGCGCATTGCTCAAGGAGCACATGGATGCGGGTGATCATTCGCCTGTAAAATCCACTCGTGGCAAACGTAGTGTCAAGACAATTGAACGCACGGATTGCGCCATTTGTGACAAGAACTTTGATAGCACCGAAACGCTAAGAAATCACATACGCAATGTGCATGAATGTGATCCGGATGATATCTTTGGCACTGGGCCACCAGCCAAGCGTAAAGCCAACTCGAAAAAGCTTATTGTGCTGGAGGATGAAGTGgaagacgatgacgatgatgatgatgctgatgcagtTGAAGACAAGGACTCTGAGGATGAGGAGACAGCGGAAGAAGTATTGCCCAATACATCAGCTGGTTCGCTCATCTCGAGCAAAACGGATGACAATGGCGTGGTGGTGCGCGAGTTTTTGGTGGATGAGGGTGATGGAAATGCACAGACAATAATGCTGGAGAACGAAGTGTATACGATTTTGCCACTGGAGGGAAGCAATGCTGCAGGTGAAGCAGCCACAAGTGGTAAAAATGTCAAGCCAGAGTCTAAGGAGAAGCAGCAATCGAAGGCAGTCTCGCCAGTGGTCAAGAAGGAACAGCGTAAATCATTGGCCGCCAGTTTGGCAGCTGCCATTGCTGATAATCTTGAGGAGCCGTCAAGCGATGATGATTTCACCGGCGAAGTGCTTACCGAAGAGGATCTCAAGCTCAAGGAGAACATTGCCAAGCTAATTGATATGCTTGTCGATCCGCAAACACTTAAGAAATACGACTGGCCAAACAGTTCCGAGGAGACGGTACTGTGCAAGGTCATCGAGAATTGTGGCCATGATTTGGCTAAAGGTGGAGAAAACTATGCCGAGTTGGATTATGGCAGTCGCATGCGTGAATATTGTAAACTTTTATTCACGGTTGTCATTCACAACGATTCAATTAAATCGCTGCTAAATAACTTTCCAATCGACGATGTTATCGAGTATGTGCTGGGCGATGAGGATCAGGATCAGGAACTGGAGCTCGACAAAGGCGCAGACAGGGAGCTAGAAAAATCCGACAACGAAACTAGACTCGATGCTGTTGACGCTGAGGCTTAA
Protein Sequence
MSANKEKLKEKEKEAKTNSDLPGGTVIKILDVAQIVSPGKEKRPSTRMKLLNDVAANKASSATPRVKQEKRTSIKILNNNEETAPTPSKGDKRSSTKTVSPTGSVKILNEKRAASSAAATPVEMAKIKTSPSKKKKMDHYVLQAIKSESSKADNTSISMSMSTSTSVVVEDEDTIDFILAENDDIELGAAKANDDEFVVSGIEEDDDDEDDDEALADASPNRTNASNSGELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLDKIERDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSELNDYPCSICNAKLRSAALLKLHEEQHQSRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCGECGKSFIQATQLRTHSKTHLRPFSCSLCTQKFKTEKQLERHVKEHTRQKRPCFACLECSRSFRTSALLKEHMDAGDHSPVKSTRGKRSVKTIERTDCAICDKNFDSTETLRNHIRNVHECDPDDIFGTGPPAKRKANSKKLIVLEDEVEDDDDDDDADAVEDKDSEDEETAEEVLPNTSAGSLISSKTDDNGVVVREFLVDEGDGNAQTIMLENEVYTILPLEGSNAAGEAATSGKNVKPESKEKQQSKAVSPVVKKEQRKSLAASLAAAIADNLEEPSSDDDFTGEVLTEEDLKLKENIAKLIDMLVDPQTLKKYDWPNSSEETVLCKVIENCGHDLAKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQDQELELDKGADRELEKSDNETRLDAVDAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00569117;
90% Identity
-
80% Identity
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