Dimm008027.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila immigrans
Gene Symbol
su(Hw)
Assembly
GCA_963583835.1
Location
OY757142.1:20086058-20089225[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00064 0.042 14.3 2.2 1 20 207 226 207 228 0.94
2 12 2.7e-06 0.00017 21.8 0.4 3 23 279 300 277 300 0.93
3 12 0.019 1.2 9.7 0.1 1 23 306 328 306 328 0.95
4 12 5.2e-07 3.4e-05 24.0 2.4 1 21 335 355 335 356 0.95
5 12 3.1e-06 0.0002 21.6 0.6 2 23 368 389 367 389 0.96
6 12 0.0001 0.0066 16.8 5.3 1 23 400 422 400 422 0.99
7 12 7.7e-05 0.0051 17.2 0.9 1 23 428 450 428 450 0.97
8 12 1.6e-05 0.001 19.4 0.8 1 23 456 478 456 478 0.99
9 12 4.3e-07 2.9e-05 24.3 2.1 1 23 484 506 484 506 0.98
10 12 0.0051 0.34 11.5 3.3 1 23 510 532 510 532 0.96
11 12 2.9e-05 0.0019 18.5 0.2 1 20 540 559 540 564 0.93
12 12 8.6e-05 0.0057 17.0 0.3 3 23 584 605 582 605 0.96

Sequence Information

Coding Sequence
ATGGCTGACGCTGGAACAGTGATCAAGATTCTCGATGTCTCACAAATCGCATCGCCCAAGGACAAAACGAGGCCGGGAAATCGGATGAAGCTGCTCAACGATGTGCCCGCGAAGGGCAGCAAAAAGGCTACCTCCGTTTCGCCGCGTGTCAAGCAGGAGAAGCGAGCGAGCATCAAAATACTGAACACGGATGAGACGACCCCAAAGAGCGACAAGCGATCATCGGCCACCAAAACTGTGAGTCCCACGGGCAGCGTCAAGATCCTGAACGAGAAGCGGGCCGCGGTGGCAACGACGCCTGTGGAGACGACCAAGATCAAGACGTCGCCGagtaaaaagaagaaaatggaTCATTATGTGCTGCAGGCCATCAAGAGtgagaacagcagcagcaaggcgGACAACACACCAAACAGCAGCGTGGTGGTGGATGAGGAGGATACCATTGACTTTATACTCGCGGAGAACGATGAGATCGAGCTGGCGGCAGCCAAGGCAAACGATGAAGAATTCGTGGTGTCGGGCATTGAGGAGGACGACGATGAAGACGAGGATGCCGTGGTGGAGGGCGGCTCGAATCGCACCAGTGGCACCAGCGAACTGAAGGAGATGGTGGAGCATGTGTGCGGCAAGTGCTACAAGACATTCCGACGGGTCAAGAGCCTCAAGAAGCACTTGGAGTTTTGTCGCTACGACAGCGGCTATCATCTGCGCAAAGCGGACATGCTCAAGAACCTCGAGAAGATCGAGCGCGATGCGGTGGTCATGGAGAAGAAAGATATTTGCTTCTGCTGCAGCGAGAGCTACGACACCTTCCATCTGGGTCACATCAATTGCCCCGATTGCCCCAAGTCGTTCAAGACCCAGACCAGCTACGAGCGTCACATCTTCATCACTCACTCCGAGCTCAACGATTACCCTTGCTCCATTTGCAATGCCAAGCTGCGCAGCGCGGCTCTATTGAAGCTGCACGAGGAGCAGCATCAGTCGCGTGGCAAGCCGTACGCCTGCAAGATCTGTGGCAAGGACTTTACGCGCTCGTATCACCTGAAGCGGCATCAGAAGTACTCGTCGTGTTCGGCCAATGAGAACGACACCATGAGCTGTAAGGTGTGCGATCGCGTCTTCTATCGCCTAGACAATTTGCGGGCGCATCTCAAACAGCATTTGGGCACACAGGTGGTCAAGAAGCCGGAATACATGTGCCATGTGTGCAAGAACTGCTTCTACAGCCTCTCCACGCTGAACATTCATATTCGCACGCACACAGGCGAGAAGCCCTTTGACTGCGATCTGTGCGATAAGAAGTTCTCCGCCTTGGTGGCGCTCAAGAAGCATCGTCGCTATCACACCGGCGAGAAACCTTACACCTGCACAGTGTGCAGTCAATCGTTTGCCGTCAAGGAGGTGCTGAATCGCCACATGAAACGGCACACGGGCGAGCGTCCGCACAAGTGTCCCGAGTGCGGCAAGAGCTTCATACAGGCCACTCAGCTGCGCACGCATTCCAAGACGCATCTGCGTCCCCATTCCTGCTCCTTGTGCAGCCAAAAGTTCAAAACGGAGAAGCAGCTGGATCGCCATGCTAAGGAGCACACGCGTTCCAAGCGTGCTTCATTCCCTTGCACAGACTGCTCGCGCAGCTTCCGCACCAGCGCACAGCTAAAGGAGCACGTGGATGCCGGCGATCATTCACCTGTAAAAGCAACGCGTGCCAAGCGCACGGTCAAGATGATCGAGCGGACGGACTGCGCCATCTGCGACAAGAACTTCGACAGCACTGAAACCTTGAGGAACCACATACGCAACGTGCACGAATGCGATCCGGATGACATCTTTGGCACAGAGCCACCCACCAAGCGTAAGGCTACCAATAAAAAGACAATTGTGTTGGAAGATGAAGAGGAGGTGAATGAAGATATGGCGCAAGCCAACACATCGGCTGGTTCGCTCATCTCGAGCAAAACAGACGACAATGGCGTTGTTGTGCGTGAGTTCCTGGTGGATGAGGGTGATGGCAATGCACAGACCATTCTGCTGGAGAACGAAGTCTACACCATTCTGCCCTTGGATGGTGGCTCGGAGACACCAGCAGCCACAAGCAGCGATGTCAAACACAACAGTGTGAAGGAGAAGGCGTCATCGGAAGTGTCGCCAGTCGTGAAGAAGGAGCAGCGCAAGTCGTTGGCTGCCAGCTTGGCAGCTGCTATTGCCGATAACACTGAGGAGCCGTCTAGCGATGATGAATTCACCGGCGAGGTGCTCACCGAAGAGGATCTTAAGCTGAAGGAGAATATTGCCAAGTTGATCGACATGCTGGTCGATCCGCAAACACTCAAGAAGTACAACTGGCCGAACAGCTCCGAGGAGACGGTGCTGTGCAAGGTCATCGAGAATTGTGGCCACGATCTGGCCAAGGGAGGCGAGAACTACGCCGAACTAGACTACGGCAGTCGCATGCGCGAATATTGCAAACTGCTCTTCACAGTCGTCATACACAACGATTCGATCAAGTCACTGTTGAACAATTTCCCCATTGACGATGTCATTGAGTATGTGCTGGGCGATGAGGATCAGGATCAAGACATGGGCAAGGGCGACGAGAAAGAGGGGGCCGAAAAGTCAAATGCAGACACAGATGTGGAGGACACTCTCGCGGTCGTGGAAGCCGAGGCTTAA
Protein Sequence
MADAGTVIKILDVSQIASPKDKTRPGNRMKLLNDVPAKGSKKATSVSPRVKQEKRASIKILNTDETTPKSDKRSSATKTVSPTGSVKILNEKRAAVATTPVETTKIKTSPSKKKKMDHYVLQAIKSENSSSKADNTPNSSVVVDEEDTIDFILAENDEIELAAAKANDEEFVVSGIEEDDDEDEDAVVEGGSNRTSGTSELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIERDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSELNDYPCSICNAKLRSAALLKLHEEQHQSRGKPYACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCPECGKSFIQATQLRTHSKTHLRPHSCSLCSQKFKTEKQLDRHAKEHTRSKRASFPCTDCSRSFRTSAQLKEHVDAGDHSPVKATRAKRTVKMIERTDCAICDKNFDSTETLRNHIRNVHECDPDDIFGTEPPTKRKATNKKTIVLEDEEEVNEDMAQANTSAGSLISSKTDDNGVVVREFLVDEGDGNAQTILLENEVYTILPLDGGSETPAATSSDVKHNSVKEKASSEVSPVVKKEQRKSLAASLAAAIADNTEEPSSDDEFTGEVLTEEDLKLKENIAKLIDMLVDPQTLKKYNWPNSSEETVLCKVIENCGHDLAKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQDQDMGKGDEKEGAEKSNADTDVEDTLAVVEAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00569117;
90% Identity
iTF_00509233;
80% Identity
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