Dlim014321.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila limbata
Gene Symbol
su(Hw)
Assembly
GCA_963924055.1
Location
OZ001352.1:29834061-29837963[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0007 0.071 14.2 2.2 1 20 257 276 257 278 0.94
2 12 2.9e-06 0.00029 21.7 0.4 3 23 329 350 327 350 0.93
3 12 0.027 2.7 9.2 0.1 1 23 356 378 356 378 0.95
4 12 5.7e-07 5.8e-05 23.9 2.4 1 21 385 405 385 406 0.95
5 12 3.4e-06 0.00035 21.5 0.6 2 23 418 439 417 439 0.96
6 12 0.00011 0.011 16.7 5.3 1 23 450 472 450 472 0.99
7 12 8.5e-05 0.0086 17.1 0.9 1 23 478 500 478 500 0.97
8 12 1.7e-05 0.0017 19.3 0.8 1 23 506 528 506 528 0.99
9 12 1.7e-06 0.00017 22.5 2.5 1 23 534 556 534 556 0.98
10 12 5.9e-05 0.006 17.6 1.5 1 23 560 582 560 582 0.97
11 12 2.1e-05 0.0021 19.0 0.1 1 20 590 609 590 614 0.92
12 12 9.5e-05 0.0096 16.9 0.3 3 23 634 655 632 655 0.96

Sequence Information

Coding Sequence
ATGCCTGGTAACTCTAATTATCAAACAGCTGATCGCATGTGTACATTCCTGCGAACCGATTGCAGACACTTCGAGCCAATGAGCACCAACAAGGAGGGCAAAATGGCTGACGCCCCTAAGGCGACCCCCGTCCCCAGTTCTGAAGCTGGAGCTGTCAATAAAGTATCCGATGTCGGGAAGAGCGTAACTCCCAAGGAAAAAAGGCCTAGTACTCGCATGAAACTGCTCAATGATGTGACAGCCAAAGGCGGTGGCAAGAATGCAACAGTATCGCCGCGTGTTAAGCAGGAGAAGCGTACAAGCATCAAAATACTGAACAATGATGAAACCACTATCACGGGCACTCCCAAAGGCGACAACAGACGCTCCGCAACTGCAACTAAAACAACTGTGAGCCCCACTGGAAGTGTCAAGATATTAAACGAGAAGCGCACTGCGCCCGTTGCCACTCCGGTTGAAACGGCCAAGATAAAGACATCGCCaagtaaaaagaagaaaatggATCACTATGTGCTGCAGGCAATAAAAAGCGAGGGCAGTAAAGCAGACAACACAACAACCAGCATAGAGATTGAGGATGAGGATACTATCGACTTTATACTTGCCGAGAATGATGACATCGAGCTGGGAGCAGCCAAAGCAAATGAAGATGAGCTTGTTGTCTCTGGCGTTGAGGaagatgacgatgatgatgatgatgaggcaTTGGGCGAAGGCAGCCCAAACCGCACAACTGGCACCAATGGCGAGCTAAAGGAAATGGTCGAGCACGTGTGCGGCAAGTGCTATAAGACATTCCGACGCGTCAAGAGCCTCAAAAAGCACTTGGAGTTCTGTCGCTATGACAGTGGTTATCATCTTCGCAAGGCGGACATGCTTAAGAATCTGGAGAAGATCGAAAAGGATGCTGTGGTCATGGAGAAGAAAGACATATGCTTCTGCTGCAGCGAGAGCTACGACACTTTTCATCTTGGCCACATTAATTGTCCAGATTGCCCCAAGTCGTTCAAGACACAGACCAGCTATGAGCGTCACATCTTCATCACTCACTCCGAGCTCAATGATTTCCCCTGCTCCATTTGCAATGCCAAACTACGTAGCGCTGCCCTGTTGAAGTTGCATGAGGAGCAGCATCAGTCGCGTGGCAAGCCATACGCCTGCAAGATCTGTGGCAAGGACTTTACTCGCTCATACCATCTCAAGCGTCATCAGAAGTACTCATCGTGCTCGGCCAATGAGAATGATACCATGAGCTGCAAGGTGTGCGATCGTGTCTTCTATCGCTTGGACAACCTACGAGCCCATCTCAAGCAGCACTTGGGCACTCAGGTGGTAAAGAAGCCGGAATACATGTGTCATGTGTGCAAGAACTGTTTCTATAGCCTGTCTACGCTCAACATTCACATACGCACTCACACCGGTGAGAAACCCTTCGACTGCGACCTGTGTGACAAGAAGTTTTCTGCCTTGGTGGCGCTCAAGAAGCATCGTCGTTATCACACGGGCGAGAAACCCTACACTTGCACAGTGTGCAGTCAGTCGTTTGCAGTCAAGGAAGTTCTCAATCGCCACATGAAGCGACACACTGGCGAACGTCCACACAAGTGCGACGAGTGCGGTAAGAGCTTCATACAGGCAACCCAGCTACGTACGCATTCCAAGACGCATCTGCGTCCGTTTCCATGCTCCATGTGCACCCAAAAGTTCAAGACAGAGAAGCAGCTTGAGCGCCACGTTAAGGAGCATACGCGTCAGAAACGCCTCAACTTCGTATGCCTGGATTGTCCACGTAGTTTTCGCACTAGCGCACAGCTCAAGGAGCACATTGACGCCGGCGATCATTCGCctGTAAAACCGACTCGGGCCAAGCGAACTGCCAAGATGATTGAGCGCACGGACTGTGCCATCTGTGACAAGAACTTTGACAGCACAGAAACACTAAGGAACCACATACGCAACGTACACGAATGCGATCCGGATGATATCTTTGGCACTGGACCACCCGCCAAACGTAAAGCTAAAAAGACCATTGTGGTGGAAGAGGAGTTGGAAGTGTTggatgaggaggaggagcaggaggttgaggaagtggcagcagcaaatACATCAGCCGGATCGCTCATCTCCAGCAAAACAGATGACAATGGCGTTGTGGTGCGCGAGTTCTTGGTGGACGAGGGAGATGGAAGTGCCCAGACCATAATGCTCGAGAATGAAGTCTACACCATTTTGCCCTTGGAGGGAGAAGGCGCTACCGAGACTCCAGCAGCTGCTAGTGAGACGAAGAAAGATCCTAAGGAGAAGCAGTTGGAGGTTGTCTCGCCTGTGGTCAAGAAGGAGCAGCGCAAATCCCTGGCTGCTAGCCTGGCAGCTGCCATTGCTGATAATCTGGAGGAGCCATCGAGCGATGATGAGTTCACCGGCGAGGTGCTCACCGAAGAGGATCTAAAGCTCAAGGAGAACATTGGCAAGTTAATCGACATGCTTGTCGATCCGCAAACACTAAAGAAATACGGCTGGCCGAACAGCTCCGAGGAGACTGTACTATGCAAGGTCATCGAGAACTGTGGCCACGATCTGGCCAAGGAAGGAGAGAACTATGCCGAGTTGGACTACGGCAGTCGCATGCGCGAATATTGCAAGCTCCTGTTCACAGTTGTCATCCACAATGATTCCATCAAATCGCTGCTAAATAATTTCCCAATTGACGAAGTTATTGAATATGTGCTGGGCGATGAGGATCAGGAAGAAGAACTGGCATTAGGCGAAGAGAAGGAGCCGGAAAAGTCCGATACGGAGGCCAGACTGGATGCCGTTGAAGCTGAGGCTTAA
Protein Sequence
MPGNSNYQTADRMCTFLRTDCRHFEPMSTNKEGKMADAPKATPVPSSEAGAVNKVSDVGKSVTPKEKRPSTRMKLLNDVTAKGGGKNATVSPRVKQEKRTSIKILNNDETTITGTPKGDNRRSATATKTTVSPTGSVKILNEKRTAPVATPVETAKIKTSPSKKKKMDHYVLQAIKSEGSKADNTTTSIEIEDEDTIDFILAENDDIELGAAKANEDELVVSGVEEDDDDDDDEALGEGSPNRTTGTNGELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSELNDFPCSICNAKLRSAALLKLHEEQHQSRGKPYACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCDECGKSFIQATQLRTHSKTHLRPFPCSMCTQKFKTEKQLERHVKEHTRQKRLNFVCLDCPRSFRTSAQLKEHIDAGDHSPVKPTRAKRTAKMIERTDCAICDKNFDSTETLRNHIRNVHECDPDDIFGTGPPAKRKAKKTIVVEEELEVLDEEEEQEVEEVAAANTSAGSLISSKTDDNGVVVREFLVDEGDGSAQTIMLENEVYTILPLEGEGATETPAAASETKKDPKEKQLEVVSPVVKKEQRKSLAASLAAAIADNLEEPSSDDEFTGEVLTEEDLKLKENIGKLIDMLVDPQTLKKYGWPNSSEETVLCKVIENCGHDLAKEGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDEVIEYVLGDEDQEEELALGEEKEPEKSDTEARLDAVEAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00569117;
90% Identity
iTF_00601967;
80% Identity
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