Dsia002359.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila siamana
Gene Symbol
su(Hw)
Assembly
GCA_035047445.1
Location
JAWNPP010000004.1:18549397-18552389[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00063 0.038 14.3 2.2 1 20 213 232 213 234 0.94
2 12 2.6e-06 0.00016 21.8 0.4 3 23 285 306 283 306 0.93
3 12 0.024 1.4 9.3 0.1 1 23 312 334 312 334 0.95
4 12 5.1e-07 3.1e-05 24.0 2.4 1 21 341 361 341 362 0.95
5 12 3.1e-06 0.00018 21.6 0.6 2 23 374 395 373 395 0.96
6 12 9.8e-05 0.0059 16.8 5.3 1 23 406 428 406 428 0.99
7 12 7.6e-05 0.0046 17.2 0.9 1 23 434 456 434 456 0.97
8 12 1.5e-05 0.00092 19.4 0.8 1 23 462 484 462 484 0.99
9 12 4.3e-07 2.6e-05 24.3 2.1 1 23 490 512 490 512 0.98
10 12 0.005 0.3 11.4 3.3 1 23 516 538 516 538 0.96
11 12 5e-05 0.003 17.7 0.2 1 21 546 566 546 570 0.92
12 12 8.4e-05 0.0051 17.0 0.3 3 23 590 611 588 611 0.96

Sequence Information

Coding Sequence
ATGTCGGACGCCGCTGCCGATGCTGCgactgtaattaaaattgtcgATGTCGCACAAATTGCGCCTCCCAAGGACAAGACAAGGCCAGGCAATCGCATGAAGCTGCTCAATGATGTGCCACCCAAAGGTGCAAAGAAGGCCGCGTCAGTCTCGCCGCGTGTCAAGCAAGAGAAACGGGCGAGCATCAAGATACTTAACACTGCGGATGAGACACCGAAGGCCGACAAAGGCCGATCGGCTAACAAAACTGTGAGTCCCACTGGCAGCGTGAAGATATTGAACGAGAAGCGCATGGCATCCGCTACGACACCCGTGGAGACGGCAAAGATCAAGACATCGCccagcaaaaagaagaaaatggATCATTATGTGCTGCAGGCCATCAAAAGtgagaacagcagcagcaaggcgGACAACAACACTTCGACGAGTAGCGTCGTGGTGGATGAGGAAGATACCATTGACTTTATACTCGCTGAGAACGATGAGATCGAGttggcagcagccaaagcgaaTGACGATGAATTCGTTGTTTCGGGCATTGAggaggacgatgacgacgatgaggatgcTTTGATTGAAGGCGGATCGAATCGcacaagtggcaacaacagcgaactAAAGGAGATGGTGGAGCATGTGTGCGGCAAGTGTTACAAGACATTCCGACGCGTCAAAAGCCTCAAAAAGCACTTGGAGTTCTGTCGCTATGACAGCGGTTATCATCTGCGCAAAGCGGACATGCTCAAAAATCTGGATAAAATCGAACGGGATGCGGTGGTCATGGAGAAAAAAGAcatttgcttctgctgcagcgAGAGCTACGACACCTTTCATCTTGGTCACATCAATTGTCCCGATTGTCCCAAGTCGTTCAAGACACAGACCAGCTACGAGCGTCACATTTTCATCACTCACTCCGAGCTCAATGATTTCCCTTGCTCCATTTGCAATGCCAAGTTGCGCAGCGCGGCGTTGTTGAAGCTGCACGAAGAGCAGCATCAGTCGCGTGGCAAGCCGTATGCCTGCAAGATCTGTGGCAAGGACTTTACGCGCTCGTACCATCTGAAGCGTCATCAAAAGTACTCGTCTTGCTCGGCGAATGAGAACGACACCATGAGCTGCAAAGTGTGCGATCGTGTCTTCTATCGCCTGGACAATTTGCGTGCGCATCTGAAGCAGCACTTGGGCACACAGGTGGTCAAGAAGCCGGAATACATGTGCCATGTGTGCAAGAACTGCTTCTACAGCCTGTCTACACTAAACATTCACATACGCACGCACACCGGTGAAAAACCTTTCGATTGCGATCTGTGCGACAAGAAGTTCTCTGCCTTGGTGGCACTCAAGAAGCATCGCCGTTATCACACCGGCGAGAAACCTTACACCTGCACAGTGTGCAGTCAATCGTTTGCTGTCAAGGAGGTGCTGAATCGTCACATGAAACGACACACTGGGGAGCGTCCTCACAAGTGCCCCGAGTGCGGCAAGAGCTTCATACAGGCCACACAGCTGCGCACGCATTCCAAGACGCATCTGCGTCCCCATTCCTGCTCCTTGTGCAGCCAAAAGTTCAAAACAGAAAAGCAGCTGGATCGCCATGCTAAGGAACACACGCGTGCCAAGCGTGCTTCATTCGCTTGCACCGAGTGCTCGCGTAGCTTCCGCACCAGCGTACTGCTGAAGGAGCACATGGATGCCGGCGATCATTCGCCTGTTAAAACGACGCGTGCTAAGCGCACCGTTAAGATGATCGAGCGCACGGACTGCGCCATCTGCGACAAGAACTTCGATAGCACTGAAACCCTAAGGAATCACATACGCAACGTCCACGAATGCGATCCGGACGATATCTTTGGCACAGAGCCACCCGCCAAGCGCAaggctgcaaataaaaaggcCATTGTATtggacgacgatgaggacgaagATGAAGATGCGGCGCCCGCTAACACATCAGCTGGCTCGCTCATCTCAAGCAAAACTGACGACAATGGTGTTGTGGTGCGTGAATTCCTGGTGGATGAAGGCGATGGCAATGCACAAACTATTCTGCTGGAGAACGAAGTCTACACCATTCTGCCCTTGGAGGGCGGCAGTGAgacgccagctgcagcagcaagcagcgatGTCAAGCCCAATGCCAAGGAGAAGCCATCACCGGTTGTGTCGCCGGTCGTGAAGAAGGAGCAGCGCAAGTCCTTGGCCGCCAGTTTGGCAGCTGCTATTGCCGATAACATTGAGGAGCCGTCTAGCGATGATGAATTCACCGGCGAGGTGCTTACCGAAGAGGACATAAAGCTCAAAGAGAATATTGCCAAGTTGATTGACATGCTGGTCGATCCGCAAACACTCAAGAAGTACAACTGGCCAAACAGCTCCGAGGAGACGGTGTTGTGCAAGGTCATCGAGAACTGTGGCCACGATCTGGCCAAGGGAGGCGAGAACTATGCCGAACTAGACTATGGCAGTCGCATGCGCGAATATTGCAAACTGCTGTTCACAGTTGTCATACACAACGATTCGATCAAGTCGCTGTTGAATAACTTCCCCATCGACGATGTCATCGAGTATGTGCTGGGCGACGAGGATCAGGAGCAAGACATGGAAAAGGGCGACGAGAAGGAAGAGGCCGCCGAAAAGTCGGATGCGGAGAACACACCGGAGACGGTTGAAGCCGAGGCTTAA
Protein Sequence
MSDAAADAATVIKIVDVAQIAPPKDKTRPGNRMKLLNDVPPKGAKKAASVSPRVKQEKRASIKILNTADETPKADKGRSANKTVSPTGSVKILNEKRMASATTPVETAKIKTSPSKKKKMDHYVLQAIKSENSSSKADNNTSTSSVVVDEEDTIDFILAENDEIELAAAKANDDEFVVSGIEEDDDDDEDALIEGGSNRTSGNNSELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLDKIERDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSELNDFPCSICNAKLRSAALLKLHEEQHQSRGKPYACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCPECGKSFIQATQLRTHSKTHLRPHSCSLCSQKFKTEKQLDRHAKEHTRAKRASFACTECSRSFRTSVLLKEHMDAGDHSPVKTTRAKRTVKMIERTDCAICDKNFDSTETLRNHIRNVHECDPDDIFGTEPPAKRKAANKKAIVLDDDEDEDEDAAPANTSAGSLISSKTDDNGVVVREFLVDEGDGNAQTILLENEVYTILPLEGGSETPAAAASSDVKPNAKEKPSPVVSPVVKKEQRKSLAASLAAAIADNIEEPSSDDEFTGEVLTEEDIKLKENIAKLIDMLVDPQTLKKYNWPNSSEETVLCKVIENCGHDLAKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQEQDMEKGDEKEEAAEKSDAENTPETVEAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00569117;
90% Identity
iTF_00509233;
80% Identity
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