Dsub017794.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila suboccidentalis
Gene Symbol
su(Hw)
Assembly
GCA_037043435.1
Location
JBAMBK010002589.1:794464-799050[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00075 0.054 14.2 2.2 1 20 258 277 258 279 0.94
2 12 3.1e-06 0.00023 21.7 0.4 3 23 330 351 328 351 0.93
3 12 0.022 1.6 9.6 0.1 1 23 357 379 357 379 0.95
4 12 8.4e-07 6.1e-05 23.5 2.5 1 21 386 406 386 407 0.95
5 12 3.6e-06 0.00027 21.5 0.6 2 23 419 440 418 440 0.96
6 12 0.00012 0.0085 16.7 5.3 1 23 451 473 451 473 0.99
7 12 9.1e-05 0.0066 17.1 0.9 1 23 479 501 479 501 0.97
8 12 1.8e-05 0.0013 19.3 0.8 1 23 507 529 507 529 0.99
9 12 1.8e-06 0.00013 22.5 2.5 1 23 535 557 535 557 0.98
10 12 4.4e-05 0.0032 18.1 1.2 1 23 561 583 561 583 0.97
11 12 2.2e-05 0.0016 19.0 0.1 1 20 591 610 591 615 0.92
12 12 0.0001 0.0073 16.9 0.3 3 23 635 656 633 656 0.96

Sequence Information

Coding Sequence
ATGCCACTGGTCACTCTAATTATCAAACAGCTGATTGGATGTGTACGTAAACTATTCCTGCGAACGGATTGGAGACACTTCGGGCCAATGAGCACCAAAATGGCTGACGCCCCTAAGGCGACCCCCGTCCCCAGTACGGACGCTGGAGCTGTCACTAAAATATCGGATGTCGGGAAAAGCGCAACTCCCAAGGAAAAACGGCCGAGTACGCGCATGAAACTGCTCAATGATGTGACCGCCAAAGGCGGTGGCAAGACCGCAACAGTCTCGCCGCGTGTGAAGCAGGAGAAGCGCACGAGCATCAAAATACTCAACAATGAGGAAGCCACGACCACGAGCACGAGCACTCCTAAAGGCGACAACAGACGCGCCGCAACGGCAACTAAAACAACTGTGAGCCCCGCTGGCAGTGTCAAGATATTAAACGAGAAGCGCACTGCGTCCGTTGCCACGCCGGTTGAAACGGCCAAGATAAAAACATCGCCgagcaaaaagaagaaaatggaTCACTATGTGCTGCAGGCAATAAAGAGCGAGGGCAGTAAGGCGGACAACACAACAGCCAGCATAGAGATTGAGGATGAGGATACTATTGACTTTATTCTCGCCGAGAATGATGACATCGAGCTGGGAGCAGCCAAGGCAAATGAAGATGAGCTTGTTGTCTCTGGCGTTGAGgaagatgacgatgatgatgatgacgaggcATTGGGCGAGGGCAGTCCAAACCGCACAGCTGGCACCAATGGCGAACTGAAGGAAATGGTCGAGCACGTGTGCGGCAAGTGCTATAAGACATTCCGACGCGTCAAGAGCCTGAAAAAGCACTTGGAGTTCTGTCGCTATGACAGTGGCTATCATCTGCGCAAGGCGGACATGCTTAAGAATCTGGAGAAGATCGAAAAGGATGCTGTGGTCATGGAGAAGAAAGACATATGCTTCTGCTGCAGCGAGAGTTACGACACTTTTCATCTTGGCCACATTAATTGTCCAGATTGCCCCAAGTCGTTCAAGACACAGACCAGCTATGAGCGTCACATCTTCATCACCCACTCCGAGCTCAATGATTACCCCTGCTCCATTTGCAATGCCAAGCTACGCAGCGCTGCCCTGTTGAAGTTGCACGAGGAGCAGCACCAGTCGCGTGGCAAGCCATTCGCCTGCAAGATCTGTGGCAAGGACTTTACTCGCTCGTATCATCTCAAGCGTCATCAGAAGTACTCGTCGTGCTCGGCCAATGAGAACGATACCATGAGCTGCAAGGTGTGCGATCGTGTCTTCTATCGCCTGGACAATCTGCGTGCTCATCTCAAGCAGCACTTGGGCACTCAGGTGGTCAAGAAGCCGGAGTACATGTGTCACGTGTGCAAGAACTGCTTCTATAGCCTCTCTACGCTCAACATTCACATACGCACTCACACTGGTGAGAAACCCTTCGACTGCGATCTGTGCGACAAGAAGTTCTCCGCCTTGGTGGCGCTCAAGAAGCATCGTCGCTATCACACGGGCGAGAAGCCCTACACCTGCACAGTGTGCAGTCAATCGTTTGCAGTCAAGGAAGTGCTCAATCGCCACATGAAGCGACACACGGGCGAGCGTCCGCACAAGTGCGACGAGTGCGGCAAGAGCTTCATCCAGGCAACTCAGCTACGTACGCATTCCAAGACGCATCTGCGTCCCTATCCCTGCTCCATGTGCAGCCAAAAGTTCAAGACCGAGAAGCAACTTGAGCGCCACGTCAAGGAGCATTCGCGTCAGAAACGCCTTAGCTTCGTATGCCTGGATTGTCCACGTAGTTTCCGCACCAGCGCACAGCTCAAGGAGCACATTGACGCCGGCGATCATTCGCCTGTAAAACCGACTCGGGCCAAGCGAACTGCCAAGATGATCGAGCGCACGGACTGTGCCATCTGTGACAAGAACTTTGACAGCACAGAGACACTAAGGAACCACATACGCAACGTGCACGAATGCGATCCGGATGATATCTTTGGCACAGGGCCACCCGCCAAACGTAAAGCTAAAAAGACCATTGTGGTGGACGAGGAGGTGGAAGTGCTGGATGAGGTGGAGGAGCAGGAGGTAGAGGAGGTGGCAGCAGCAAATACATCAGCAGGTTCGCTCATCTCCAGCAAAACGGATGACAATGGCGTTGTGGTGCGCGAGTTCTTGGTGGACGAGGGAGATGGCAGTGCCCAGACCATAATGCTCGAGAATGAAGTCTACACCATTTTGCCGTTGGAGGGAGAAGGCGCTACCGAGACACCAGCAGCTGCAAGTGAGGCGAAGAAAGATCCGAAGGAGAAGCAGACGGAGGTTGTCTCGCCAGTGGTCAAGAAGGAGCAGCGCAAATCTCTGGCTGCTAGCTTGGCAGCTGCCATTGCCGACAATCTGGAGGAGCCATCGAGCGATGATGAGTTCACCGGCGAGGTGCTCACCGAAGAGGACCTGAAGCTCAAGGAGAACATTGGCAAGTTGATCGACATGCTTGTCGATCCGCAAACACTGAAGAAGTACGGCTGGCCGAACAGCTCCGAGGAGACGGTGCTATGCAAGGTCATCGAGAACTGTGGCCACGATCTGGCCAAGGAGGGAGAGAACTATGCCGAGTTGGACTACGGCAGTCGCATGCGCGAATATTGCAAGCTCCTGTTCACAGTTGTCATCCACAATGATTCGATCAAATCGCTGCTAAATAACTTTCCAATTGACGAAGTTATTGAATATGTGCTGGGCGACGAGGATCAGGACGAGGATCTGGCAATTGGCGAAGAGAAGGAATCTGAAAAGTCCGATACAGCGGCCAGACTGGATGCCGTGGAAGCTGAAGCCTGA
Protein Sequence
MPLVTLIIKQLIGCVRKLFLRTDWRHFGPMSTKMADAPKATPVPSTDAGAVTKISDVGKSATPKEKRPSTRMKLLNDVTAKGGGKTATVSPRVKQEKRTSIKILNNEEATTTSTSTPKGDNRRAATATKTTVSPAGSVKILNEKRTASVATPVETAKIKTSPSKKKKMDHYVLQAIKSEGSKADNTTASIEIEDEDTIDFILAENDDIELGAAKANEDELVVSGVEEDDDDDDDEALGEGSPNRTAGTNGELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSELNDYPCSICNAKLRSAALLKLHEEQHQSRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCDECGKSFIQATQLRTHSKTHLRPYPCSMCSQKFKTEKQLERHVKEHSRQKRLSFVCLDCPRSFRTSAQLKEHIDAGDHSPVKPTRAKRTAKMIERTDCAICDKNFDSTETLRNHIRNVHECDPDDIFGTGPPAKRKAKKTIVVDEEVEVLDEVEEQEVEEVAAANTSAGSLISSKTDDNGVVVREFLVDEGDGSAQTIMLENEVYTILPLEGEGATETPAAASEAKKDPKEKQTEVVSPVVKKEQRKSLAASLAAAIADNLEEPSSDDEFTGEVLTEEDLKLKENIGKLIDMLVDPQTLKKYGWPNSSEETVLCKVIENCGHDLAKEGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDEVIEYVLGDEDQDEDLAIGEEKESEKSDTAARLDAVEAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00569117;
90% Identity
iTF_00585355; iTF_00586098; iTF_00533981;
80% Identity
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