Dacu000306.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila acutilabella
Gene Symbol
su(Hw)
Assembly
GCA_035046005.1
Location
JAWNOK010000003.1:2434279-2438202[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0007 0.054 14.2 2.2 1 20 255 274 255 276 0.94
2 12 2.9e-06 0.00023 21.7 0.4 3 23 327 348 325 348 0.93
3 12 0.02 1.6 9.6 0.1 1 23 354 376 354 376 0.95
4 12 7.9e-07 6.1e-05 23.5 2.5 1 21 383 403 383 404 0.95
5 12 3.4e-06 0.00026 21.5 0.6 2 23 416 437 415 437 0.96
6 12 0.00011 0.0085 16.7 5.3 1 23 448 470 448 470 0.99
7 12 8.5e-05 0.0066 17.1 0.9 1 23 476 498 476 498 0.97
8 12 1.7e-05 0.0013 19.3 0.8 1 23 504 526 504 526 0.99
9 12 1.6e-06 0.00012 22.5 3.0 1 23 532 554 532 554 0.98
10 12 0.00011 0.0084 16.7 1.3 1 23 558 580 558 580 0.97
11 12 3.3e-05 0.0026 18.4 0.1 1 20 588 607 588 612 0.92
12 12 9.4e-05 0.0073 16.9 0.3 3 23 632 653 630 653 0.96

Sequence Information

Coding Sequence
ATGTTCACGGGAAATGTGAATTGTCAGACGCCAACGCCATTGTGTACGCGTTACGTGCCAGCGCTCGTGGTTCAAACTAGTCCTTTGAACATTATTCTGGCAATGAGTGTCAACAAGGAGCGCAAAATGACCGACGTCTCCGCCTCCAGTAACAACGATGGCGGAACTGTGATCAAAATAGTGGATGTCGCACAGATCGTATCACCCAAGGAGAAGCGGCCCAGCACACGCATGAAACTACTCAACGATGTGGCGGCCAAAAGTGCCAGCAAGACCACCGCAAACTCAGCGCGTGTGAAGCAAGAGAAGCGCACAAGCATCAAGATACTTAACGATGAGACGACGACAAGCACTCCCAAGAGTGACAAACGAGCAGCCACCAAAATCGTCAGTCCTACGGCAAGTGTTAAGATATTAAACGAAAAGCGTTCGTCAGCTACTGCCACACCTGTGGAGACAGCCAAGATTAAGACTTCGCccagcaaaaagaagaaaatggaTCACTATGTGCTGCAGGCCATCAAGAGTGAGAACAGCAAAGCGGACAACACTTCCACTTCTATTGTGGTTGAGGATGAGGACACAATTGACTTTATTCTGGCTGAGAACGATGACATTGATCTGGGCGCAGCCAAGGCCAATGACGATGAGTTTGTTGTCTCGGGCGTTGAGGAggacgacgatgatgaggaAGAGGCTCTGGGTGAGGGAAGCCCCAATCGCACTAGTGGCACCAATAGTGACCTTAAGGAAATGGTGGAGCACGTGTGCGGTAAGTGCTACAAGACATTCCGACGCGTGAAGAGTCTCAAGAAGCACTTGGAATTCTGTCGCTACGACAGTGGCTATCATCTGCGCAAGGCGGACATGCTCAAGAACCTGGATAAGATCGAACGCGATGCGGTGGTCATGGAGAAGAAAGACATTTGCTTCTGCTGCAGCGAGAGCTACGACACCTTTCATCTGGGTCACATCAACTGTCCAGATTGTCCCAAATCATTCAAGACACAGACAAGCTACGAACGTCACATCTTTATCACTCACTCCGAGCTCAACGATTACCCCTGCTCCATTTGCAATGCAAAGCTCCGCAGTGCTGCGCTACTGAAGCTTCACGAGGAACAGCATCAGTCACGTGGCAAACCCTTTGCTTGCAAGATCTGCGGCAAGGACTTTACACGCTCCTATCATCTAAAGCGGCATCAGAAGTACTCCTCTTGCTCAGCTAATGAGAACGACACCATGAGCTGTAAGGTGTGCGATCGTGTTTTCTATCGTCTGGACAATTTGCGTGCTCATCTCAAGCAGCACCTGGGCACACAAGTGGTCAAGAAACCAGAGTACATGTGCCATGTGTGCAAGAACTGTTTCTACAGTCTCTCCACCTTGAACATTcatatacgcacacacacgggTGAGAAACCCTTTGACTGCGATCTATGCGACAAGAAGTTCTCCGCCTTGGTGGCACTAAAGAAGCATCGTCGTTATCATACGGGCGAGAAGCCCTACACCTGCACAGTGTGCAGCCAATCGTTTGCTGTCAAAGAGGTGCTCAATCGCCACATGAAGCGTCACACGGGCGAGCGTCCACACAAGTGCAACGAGTGCGGCAAGAGCTTCATTCAGGCCACTCAGCTACGTACTCATTCCAAGACGCATCTGCGTCCCTACGCCTGTTCGCTGTGCACCCAAAAGTTTAAGACAGAGAAACAACTTGAGCGCCATGTCAAGGAGCATACACGCCAGAAGCGTGCCAGCTTCGCCTGTCCTGACTGCCCTCGTAGTTTCCGCACCACCGTACAGCTCAAGGAGCACATTGATGCCGGTGATCATTCGCCTGTTAAAACGACACGCGCCAAGCGCACGGCCAAGGTGATTGAGCGCACGGATTGCGCCATTTGTGACAAGAACTTTGATAGCACCGAAACATTGAGGAATCACATACGCAATGTTCACGAATGTGATCCCGATGATATCTTTGGCACTGGACCACCAGCCAAGCGTCGAGCCAAAAAGGCCATTGTGATAGCGGATGAGCTGGaggatgatgacgatgatgccGACGAAGATGGCGAGGAGGCTGAAGAGGTGGAGGAAGAGGAGGCAGAGGAAGTATTGCCAAATACTTCGGCCGGATCACTTATCTCCAGCAAAACCAATGACAATGGCGTTGTAGTGCGTGAATTTCTGGTGGACGAGGGCGATGGTAATGCCCAGACAATTATGCTGGAGAATGAAGTCTATACTATTCTGCCCTTGGAGGGTAACAATGCCACCGAAGCGGCAACGTCCGGCAAGGGCGTCAAGCCCGAGTCCAAGGAGAAGGAAAAGCAATCAAAGGTTGTCTCACCGGTGGTGAAAAAGGAGCAGCGTAAATCTCTTGCTGCTAGCTTGGCCGCTGCCATTGCTGATAATCTGGAGGAGCAAGTCAGCGAAGATGATTTCGCCGGTGAAGTGCTAACCGAAGAGGATATAAAATTGAAGGAGAATATAGCCAAGTTGATTGACATGCTCGTTGATCCGCAGACACTCAAGAAATATGGCTGGCCCAACAGCTCGGAGGAGACGGTGCTGTGCAAGGTGATCGAGAACTGTGGCCACGATCTGGCCAAGGGAGGCGAGAACTACGCCGAATTGGATTATGGCAGTCGCATGCGTGAATAttgtaaacttttgtttactgtTGTCATCCACAATGATTCGATCAAGTCGCTCTTGAATAACTTTCCCATTGACGATGTCATCGAGTATGTGCTGGGCGATGAGGATCAGGAGCAGGAACTGGAGCTCGGGAAGGGCGATGAGAAACAAAACGACAAGTCCGATACGGAGACCACACAACTGGATGACGTTGAAGCCGAGGCTTAA
Protein Sequence
MFTGNVNCQTPTPLCTRYVPALVVQTSPLNIILAMSVNKERKMTDVSASSNNDGGTVIKIVDVAQIVSPKEKRPSTRMKLLNDVAAKSASKTTANSARVKQEKRTSIKILNDETTTSTPKSDKRAATKIVSPTASVKILNEKRSSATATPVETAKIKTSPSKKKKMDHYVLQAIKSENSKADNTSTSIVVEDEDTIDFILAENDDIDLGAAKANDDEFVVSGVEEDDDDEEEALGEGSPNRTSGTNSDLKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLDKIERDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSELNDYPCSICNAKLRSAALLKLHEEQHQSRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPYACSLCTQKFKTEKQLERHVKEHTRQKRASFACPDCPRSFRTTVQLKEHIDAGDHSPVKTTRAKRTAKVIERTDCAICDKNFDSTETLRNHIRNVHECDPDDIFGTGPPAKRRAKKAIVIADELEDDDDDADEDGEEAEEVEEEEAEEVLPNTSAGSLISSKTNDNGVVVREFLVDEGDGNAQTIMLENEVYTILPLEGNNATEAATSGKGVKPESKEKEKQSKVVSPVVKKEQRKSLAASLAAAIADNLEEQVSEDDFAGEVLTEEDIKLKENIAKLIDMLVDPQTLKKYGWPNSSEETVLCKVIENCGHDLAKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQEQELELGKGDEKQNDKSDTETTQLDDVEAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00569117;
90% Identity
iTF_00478875;
80% Identity
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