Doo027422.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Dicycla oo
Gene Symbol
ZFY
Assembly
GCA_948252095.1
Location
OX411736.1:2495001-2518302[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.099 12 7.6 0.7 1 23 57 79 57 79 0.97
2 12 0.18 22 6.8 4.1 1 23 86 108 86 108 0.97
3 12 0.59 72 5.2 1.1 1 15 112 126 112 135 0.82
4 12 3.9e-06 0.00048 21.5 3.6 1 23 140 162 140 163 0.95
5 12 0.0013 0.16 13.6 0.9 2 23 170 191 169 191 0.97
6 12 8.7e-06 0.0011 20.4 0.7 2 23 205 226 204 226 0.97
7 12 1.3 1.6e+02 4.1 5.0 3 23 232 253 230 253 0.95
8 12 5e-05 0.0061 18.0 3.1 2 23 264 286 263 286 0.96
9 12 0.081 9.8 7.9 0.8 1 23 293 316 293 316 0.93
10 12 0.0028 0.33 12.5 0.4 5 23 328 347 326 347 0.93
11 12 0.00011 0.013 17.0 4.6 1 23 356 378 356 378 0.98
12 12 0.00053 0.064 14.8 0.3 1 23 383 406 383 406 0.97

Sequence Information

Coding Sequence
AACGTCTCTGAAGAAAATGAACAGCAAGTGGATAATTCTCAACCTAAGATGGAAACCCCCTTGATGTACTCCTATGAAACATTAAGGAACATAGAAATTGTGACCATCGACGAAGAAGAACGTCAAAAAGAGTACCAAGAGACGTTGAAGTCGCGTCAACACATGCGTCATGTGTGTGTACACTGCGCGCTCGGCTTCGTACTCAAACAGGCGTTTGATGTGCATATGAAGGTTCATTCTCCCCAATCAGGCGACCACGAGTGCTTACTCTGCCACTCCCGTCTCAAAACCGCTGACATGTTATACCGGCACCGCTTACGGCATTATCGCCGTTACCGGTGCCTGCTTTGCCGGATGCGGTTTAAAGATAAAGACACTGCCGCCTGCCATGTCATGAACGATCATGCCGGACAGACCTTCGAGTGCGATCATTGTGGGAGAGGATTCAAACGACCGCAGTACCTGAAGAGGCACGTGGAACAGCACCACACCAAGCCCCACCATCTCGAATGTGGCGTCTGCTTCCGAGTCTTCCACGAGAGGGGCTGGTATAGGTCTCATATCAGGACTCATAACGAGGAGGTACGAGCCAAGACGGTGCGCCTGCCAGTTACCTGCGAGATTTGTTCTCGCGACTACAAGAACAAAGCAAGCCTGAAGCGTCACCTTCTCACTCACGACGAGAATGTGCACTGCGAGATCTGTTTCGAGAAGTGCAAGAATCGGATCACGTTGGGACATCACTACTTGAAAGTGCATAATGAGAAATATGTGGGTGCGCCGGAGCAGACTTGCCCGCATTGCGACCGGATCTGTGCGACGCGTGCGATGCTCAAGCGACACATACAAAGGATGCACAGCGATAGAACTAAGAAATACCAATGCGATCACTGCCAGCGGCTCTACCTGACTAAAGGCGAGGTTCGGGCCCACATCACCTGGTCACACATGCCGGCTGAAGCCCGAGGGGGCCACGCTTGCACGTGTGGTCGTATCTTCAGGAGCCCCTCGCTACTTCGCGACCATAAGGCCAGGTTCCATGCGTCACAGCCACCACCTAGGGTTCACCAATGTGAACACTGTGAAAAGGCTTTTGCGAACAAACAAGTGCTGAATCGTCACAAGAAAAGCCATTCCGACGAGATGTATCCCTGCAACGAATGTGGGTTACTCTTCAAAACTCAACCTTACGTCAAAGTCCACTACCAAATCAAACATCTAAACATGACGAGAGCACAAATCAAAGCACAGAGGAAGCTCAACAAGGAGCAGTTAATACAGAATAATATACATAGAAGTACGAATTGGGAACCATCCATCTCTGACAAGAAGAAAAGGTCAGTTGCTATTGAAAATGAAGAAGACCCTCTTCTGGTTCAGGAGGTGGATATACAAATCAAATCGGAGAAAGAAGACGATGAACTACAAATCCCGACGTTCGAAACTTTTGTTGATATTAGTAGGGAATGA
Protein Sequence
NVSEENEQQVDNSQPKMETPLMYSYETLRNIEIVTIDEEERQKEYQETLKSRQHMRHVCVHCALGFVLKQAFDVHMKVHSPQSGDHECLLCHSRLKTADMLYRHRLRHYRRYRCLLCRMRFKDKDTAACHVMNDHAGQTFECDHCGRGFKRPQYLKRHVEQHHTKPHHLECGVCFRVFHERGWYRSHIRTHNEEVRAKTVRLPVTCEICSRDYKNKASLKRHLLTHDENVHCEICFEKCKNRITLGHHYLKVHNEKYVGAPEQTCPHCDRICATRAMLKRHIQRMHSDRTKKYQCDHCQRLYLTKGEVRAHITWSHMPAEARGGHACTCGRIFRSPSLLRDHKARFHASQPPPRVHQCEHCEKAFANKQVLNRHKKSHSDEMYPCNECGLLFKTQPYVKVHYQIKHLNMTRAQIKAQRKLNKEQLIQNNIHRSTNWEPSISDKKKRSVAIENEEDPLLVQEVDIQIKSEKEDDELQIPTFETFVDISRE