Basic Information

Insect: Lithophane semibrunnea
Gene Symbol: ZFY
Assembly: GCA_947363905.1
Location: OX376211.1:11627355-11639721[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.12 9.1 7.4 0.7 1 23 111 133 111 133 0.97

2 12 0.23 17 6.6 4.1 1 23 140 162 140 162 0.97

3 12 0.64 48 5.2 1.5 1 15 166 180 166 189 0.82

4 12 4.8e-06 0.00036 21.3 3.6 1 23 194 216 194 217 0.95

5 12 0.0016 0.12 13.3 0.9 2 23 224 245 223 245 0.97

6 12 1.1e-05 0.0008 20.2 0.7 2 23 259 280 258 280 0.97

7 12 1.2 92 4.3 4.7 3 23 286 307 284 307 0.95

8 12 0.0002 0.015 16.2 1.6 3 23 319 340 318 340 0.97

9 12 0.1 7.4 7.7 0.8 1 23 347 370 347 370 0.93

10 12 0.0034 0.25 12.3 0.4 5 23 382 401 380 401 0.93

11 12 3.8e-05 0.0028 18.5 4.7 1 23 410 432 410 432 0.98

12 12 0.00067 0.05 14.5 0.4 1 23 437 460 437 460 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.12	9.1	7.4	0.7	1	23	111	133	111	133	0.97
2	12	0.23	17	6.6	4.1	1	23	140	162	140	162	0.97
3	12	0.64	48	5.2	1.5	1	15	166	180	166	189	0.82
4	12	4.8e-06	0.00036	21.3	3.6	1	23	194	216	194	217	0.95
5	12	0.0016	0.12	13.3	0.9	2	23	224	245	223	245	0.97
6	12	1.1e-05	0.0008	20.2	0.7	2	23	259	280	258	280	0.97
7	12	1.2	92	4.3	4.7	3	23	286	307	284	307	0.95
8	12	0.0002	0.015	16.2	1.6	3	23	319	340	318	340	0.97
9	12	0.1	7.4	7.7	0.8	1	23	347	370	347	370	0.93
10	12	0.0034	0.25	12.3	0.4	5	23	382	401	380	401	0.93
11	12	3.8e-05	0.0028	18.5	4.7	1	23	410	432	410	432	0.98
12	12	0.00067	0.05	14.5	0.4	1	23	437	460	437	460	0.97

Sequence Information

Coding Sequence: ATGGAAGATCTCGGTAGCATTTTATTAAAAAACCGAATATTCTCTGAGATGGAAAAAGAAACCAAACATCTGAAATCAACTTTGCCGTTAAAGAAGAGATTACAGAAGCGAGTCAAGCCAGAAGATGACGACTTCCCGAAGAAAGAAAAACCGGAAGAAAACAATGTCACTGAAGAAAATGAACAGCAAGTGGATAATTCTCAAACTAAGACGGAAACCCCCTTGATGTACTCCTACGAAACGTTACGGAACATAGAAATTGTGACCATAAATGAAGAAGAACGTCAGCAAGAGTACCAAGAGACGTTGAAATCGCGTCAACACATGCGCCATGTGTGTGTACACTGCGCGCTCGGATTCGTACTCAAACAGGCGTTTGATGTGCATATGAAAGTTCATTCTCCCCAATCAGGCGACCACGAGTGCTTACTCTGTCACTCCCGTCTCAAAACCGCCGACATGTTATACCGGCACCGCTTACGGCATTACCGCCGTTACCGATGCCTGCTCTGCCGGACGCGGTTTAAAGATAAGGACACTGCCGCCTGTCATGTCATGAACGATCATGCTGGACAGACCTTTGAGTGCGATCATTGTGGGAGAGGATTCAAACGACCGCAGTACCTGAAGAGGCACGTGGAACAGCATCACACCAAGCCCCATCATCTTGAATGTGGCGTCTGCTTCAGAGTCTTCCACGAGAGGGGCTGGTATAGGTCTCACATCAGAACACATAACGAAGAGGTACGAGCCAAGACGGTGCGCCTGCCAGTCACCTGCGAGATCTGTTCTCGCGACTACAAGAATAAAGCAAGCCTGAAGCGTCACCTTCTCACTCACGACGAGAACGTCCACTGCGAGATCTGTTACGAGAAGTGCAAGAATCGGATCACGTTGGGACATCACTATTTGAAGGTGCATAATGAGAAATATGTTGGTGCAACAGTGCAGGCTTGCTCGCTCTGCGACCGGATCTGTGCGACACGCGCCATGCTCAAGCGGCACATGCAGCGGATGCACAGCGATAGAACTAAGAAATACCAATGTGATCACTGCCAGCGCCTCTACCTGACTAAAGGCGAGGTCCGGGCCCACATCACGTGGTCGCACATGCCGGCTGAAGCCCGAGGGGGGCACGCCTGCACCTGTGGTCGCATTTTCAGGAGCCCCTCACTACTTCGCGACCATAAGGCCAGGTTCCATGCGTCACAGCCACCACCAAGGGTCCACCAGTGTGAACACTGTGATAAGGCATTTGCGAACAAACAAGTGCTGAACCGTCACAAGAAAAGCCATTCCGACGAGATGTATCCCTGCAAAGAATGCGGATTACTCTTCAAAACTCAGCCTTACGTCAAAGTCCACTACCAAATCAAACATCTAAACATGACAAGAGCACAAATCAAAGCCCAGAGGAAACTCAACAAGGAACAGTTAATACAGAATAATATATGTAAAAGTACGAATTGGGAACCACCCATCTCTGACAAGAAGAAAAGTTCAGTTGCTATTGAAATTGAAGAAGACCCTCTTTTGGTTCAGGAGGCGGATATAGAAATCAAATTGGAGCAGGAAGATGACTATCACCCGTTGGTTCAGGAGGGAGATATGGAAATCAAATCGGAGAAAGGAGAAGACCTTCAAATCCCGACGTTCCAAACCTTTGTTGATATTAGTAGAGTATAA
Protein Sequence: MEDLGSILLKNRIFSEMEKETKHLKSTLPLKKRLQKRVKPEDDDFPKKEKPEENNVTEENEQQVDNSQTKTETPLMYSYETLRNIEIVTINEEERQQEYQETLKSRQHMRHVCVHCALGFVLKQAFDVHMKVHSPQSGDHECLLCHSRLKTADMLYRHRLRHYRRYRCLLCRTRFKDKDTAACHVMNDHAGQTFECDHCGRGFKRPQYLKRHVEQHHTKPHHLECGVCFRVFHERGWYRSHIRTHNEEVRAKTVRLPVTCEICSRDYKNKASLKRHLLTHDENVHCEICYEKCKNRITLGHHYLKVHNEKYVGATVQACSLCDRICATRAMLKRHMQRMHSDRTKKYQCDHCQRLYLTKGEVRAHITWSHMPAEARGGHACTCGRIFRSPSLLRDHKARFHASQPPPRVHQCEHCDKAFANKQVLNRHKKSHSDEMYPCKECGLLFKTQPYVKVHYQIKHLNMTRAQIKAQRKLNKEQLIQNNICKSTNWEPPISDKKKSSVAIEIEEDPLLVQEADIEIKLEQEDDYHPLVQEGDMEIKSEKGEDLQIPTFQTFVDISRV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01441398;
90% Identity: iTF_00449573;
80% Identity: -