Basic Information

Insect: Lithophane ornitopus
Gene Symbol: ZFY
Assembly: GCA_948473465.1
Location: OX419638.1:1586023-1598852[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.11 7.8 7.5 0.7 1 23 101 123 101 123 0.97

2 12 0.21 14 6.6 4.1 1 23 130 152 130 152 0.97

3 12 0.58 41 5.2 1.5 1 15 156 170 156 179 0.82

4 12 4.4e-06 0.00031 21.3 3.6 1 23 184 206 184 207 0.95

5 12 0.0015 0.1 13.4 0.9 2 23 214 235 213 235 0.97

6 12 9.8e-06 0.00069 20.2 0.7 2 23 249 270 248 270 0.97

7 12 1.1 79 4.3 4.7 3 23 276 297 274 297 0.95

8 12 0.00019 0.014 16.1 3.7 3 23 309 330 308 330 0.97

9 12 0.091 6.4 7.7 0.8 1 23 337 360 337 360 0.93

10 12 0.0031 0.22 12.3 0.4 5 23 372 391 370 391 0.93

11 12 3.5e-05 0.0025 18.5 4.7 1 23 400 422 400 422 0.98

12 12 0.00061 0.043 14.6 0.4 1 23 427 450 427 450 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.11	7.8	7.5	0.7	1	23	101	123	101	123	0.97
2	12	0.21	14	6.6	4.1	1	23	130	152	130	152	0.97
3	12	0.58	41	5.2	1.5	1	15	156	170	156	179	0.82
4	12	4.4e-06	0.00031	21.3	3.6	1	23	184	206	184	207	0.95
5	12	0.0015	0.1	13.4	0.9	2	23	214	235	213	235	0.97
6	12	9.8e-06	0.00069	20.2	0.7	2	23	249	270	248	270	0.97
7	12	1.1	79	4.3	4.7	3	23	276	297	274	297	0.95
8	12	0.00019	0.014	16.1	3.7	3	23	309	330	308	330	0.97
9	12	0.091	6.4	7.7	0.8	1	23	337	360	337	360	0.93
10	12	0.0031	0.22	12.3	0.4	5	23	372	391	370	391	0.93
11	12	3.5e-05	0.0025	18.5	4.7	1	23	400	422	400	422	0.98
12	12	0.00061	0.043	14.6	0.4	1	23	427	450	427	450	0.97

Sequence Information

Coding Sequence: ATGCCTCACCCCCTCCCCCTCAAAAAAGGAACCAAACATCTGAAATCAACATTGCCGTTAAAGAAGAGATTACAGAAGCGAGTCAAGCCAGAAGATGACGACTTCCCGAAGAAAGAAAAAACGGAAGAAAACAATGTCACTGATGAAAATGAACAGCAAGTGGATAATTCTCAAACTAAGACGGAAACCCCCTTGATGTACTCCTACGAAACACTAAGGAACATAGAAATTGTGACTATCAACGAAGAAGAACGTCAGCAAGAGTACCAAGAGACGTTGAAGTCGCGTCAACACATGCGCCATGTGTGTGTACACTGCGCGCTTGGATTCGTACTCAAACAGGCGTTTGATGTGCATATGAAAGTTCATTCTCCCGATTCAGGCGACCACGAGTGCTTACTCTGTCACTCCCGTCTTAAAACCGCTGACATGTTATACCGGCACCGCTTACGGCATTACCGCCGTTACCGGTGCCTGCTTTGCCGGACGCGGTTTAAAGATAAGGACACTGCCGCTTGTCATGTCATGAACGACCATGCTGGACAGACCTTCGAGTGCGATCATTGTGGGAGAGGATTCAAACGACCGCAGTACCTGAAGAGGCACGTGGAACAGCACCACACTAAACCCCATCATCTTGAGTGTGGCGTCTGCTTCCGAGTCTTCCACGAGAGGGGCTGGTATAGGTCTCACATCAGGACGCATAACGAAGAGGTACGAGCCAAGACGGTGCGCTTGCCAGTCACCTGCGAGATCTGTTCTCGCGACTACAAGAACAAAGCAAGCCTGAAGCGTCACCTTCTCACTCACGACGAGAATGTCCACTGCGAGATCTGTTACGAGAAGTGCAAGAATCGGATCACGTTGGGACATCACTATTTGAAGGTGCATAATGAGAAATATGTTGGTGCAACAGTGCAGGCTTGCTCGCATTGCGACCGGATCTGTGCGACGCGCGCCATGCTCAAGCGACACATGCAGCGGATGCACAGCGATAGAACTAAGAAATACCAATGTGATCACTGCCAACGCCTCTACCTGACCAAAGGCGAGGTCCGGGCGCACATCACGTGGTCGCACATGCCGGCCGAAGCCCGAGGGGGGCACGCCTGCACCTGTGGCCGCATCTTCAGGAGCCCGTCGCTACTTCGCGACCATAAAGCCAGGTTCCATGCGTCACAACCACCCCCAAGGGTTCACCAGTGTGAACACTGTGATAAGGCTTTTGCGAACAAACAAGTGCTGAATCGTCACAAGAAAAGCCACTCCAACGAGATGTATCCTTGCAAAGAATGTGGATTACTCTTCAAAACTCAGCCTTACGTCAAAGTCCACTACCAAATCAAACATCTAAACATGACGAGAGCACAGATCAAAGCCCAGAGGAAACTCAACAAGGAACAGTTAATACAGAATAATATATGTAAAAGTACGAATTGGGAACCACCCATCTCTGACAAGAAAAAAAGTTCAGTTGCAATTGAAATTGAAGAAGATCCTCTTTTGGTTCAGGAGGCGGATATAGAAATCAAATTGGAGAAGGAAGATGATCTTCATCCTTTGGTTCAGGAGATAGATATAGAAATCAAATCTGAGGAAGGAGATGACCTCCAAATCCCGACGTTCCAAACCTTTGTTGATATTAGTAGAGAATAA
Protein Sequence: MPHPLPLKKGTKHLKSTLPLKKRLQKRVKPEDDDFPKKEKTEENNVTDENEQQVDNSQTKTETPLMYSYETLRNIEIVTINEEERQQEYQETLKSRQHMRHVCVHCALGFVLKQAFDVHMKVHSPDSGDHECLLCHSRLKTADMLYRHRLRHYRRYRCLLCRTRFKDKDTAACHVMNDHAGQTFECDHCGRGFKRPQYLKRHVEQHHTKPHHLECGVCFRVFHERGWYRSHIRTHNEEVRAKTVRLPVTCEICSRDYKNKASLKRHLLTHDENVHCEICYEKCKNRITLGHHYLKVHNEKYVGATVQACSHCDRICATRAMLKRHMQRMHSDRTKKYQCDHCQRLYLTKGEVRAHITWSHMPAEARGGHACTCGRIFRSPSLLRDHKARFHASQPPPRVHQCEHCDKAFANKQVLNRHKKSHSNEMYPCKECGLLFKTQPYVKVHYQIKHLNMTRAQIKAQRKLNKEQLIQNNICKSTNWEPPISDKKKSSVAIEIEEDPLLVQEADIEIKLEKEDDLHPLVQEIDIEIKSEEGDDLQIPTFQTFVDISRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01441398;
90% Identity: iTF_00449573;
80% Identity: -