Waur006976.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Wasmannia auropunctata
Gene Symbol
ZFX
Assembly
GCA_000956235.1
Location
NW:168867-180475[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 1.3 93 3.2 0.1 3 23 15 35 14 35 0.94
2 15 2.4 1.8e+02 2.4 3.8 1 23 974 997 974 997 0.81
3 15 0.0001 0.0073 16.2 1.9 3 23 1085 1106 1083 1106 0.96
4 15 0.0022 0.16 11.9 0.2 2 23 1119 1140 1119 1140 0.98
5 15 1.4e-05 0.001 18.9 2.3 2 23 1143 1164 1142 1164 0.97
6 15 0.0017 0.12 12.3 0.3 1 23 1170 1192 1170 1192 0.96
7 15 3.3e-05 0.0024 17.7 4.3 2 23 1199 1220 1198 1221 0.95
8 15 0.084 6.1 7.0 3.7 5 23 1234 1252 1233 1252 0.97
9 15 1.7e-05 0.0012 18.6 1.5 3 23 1259 1280 1258 1280 0.97
10 15 0.0077 0.57 10.2 0.3 2 23 1296 1316 1295 1316 0.97
11 15 5.1e-05 0.0038 17.1 0.7 1 20 1322 1341 1322 1344 0.92
12 15 6.4e-05 0.0047 16.8 2.7 1 23 1352 1374 1352 1374 0.99
13 15 0.0018 0.13 12.2 3.2 1 23 1380 1402 1380 1402 0.97
14 15 3.2e-06 0.00024 20.8 3.9 1 23 1408 1430 1408 1430 0.99
15 15 0.0011 0.082 12.9 6.3 1 23 1436 1458 1436 1459 0.96

Sequence Information

Coding Sequence
ATGGAGCTCAACGGCACGGGAACGCCCGTCGGGGCCGTGGCCTGTCCTGTGTGTACCCTGTATTTGCGCGAGGGCATCAGTCTGCAGAAGCATCTGGATACTCATCCCAAGGAACAGGTTATAGATGCTCTCATCAAAGCCAGCGCCTCTTCGTCGCaaacgcagcagcagcagcagcagcaacaacaactacaacagcaacagcagccCCAGCAAACTCTATCAGCATCATCGTCAGCAACGTCACTACCATTATCACTGCAGCCACAGGCTGCGCTTCAGACCCCTACCTCCATTCAGTCGCCCCAAGCGTCCTCCCAAGTATCGCAGAACGCGCAAATTTCTACTCACTCTCCGTATCCCGTAGGACCCATATTCGAATGTCCGCCCATAAGCACCATGATGCCGCCGCAGTTCACCTCATTCAGCTATCAGCAATTCGTGAACAATGGGACCATGATGATACCGCAGTACGCGATGGCGCCGCAGGCCAATCAGATGATGCAGATGCTGTACAATCCATACGGTATGTACCAACAGCAAATACCCACCGTCCAAATGATCTCACCAGTTGCAGCTATCCCGGGCGCGACGACGAGGGTACGACCGGTGGTCACTATGGCCGGGGAGAGCAACGTCAGAACCCTGACGGTTCCTGTAAATAGTCCCGAGCCGAAGCAGATTCTGCCGGAGATCTTGCCGGACGCGGAGCCCGAGTCCGGCCAGATTATGCCGGATGTGAGCCTCTCGGCGTCGCCGGTGCTGCAGAGCGAGGACGCATCCATCAGGGCGAGAGAGGAGAGCGACAGCAGCGGCACGCTGCCAATCGATCACCGAGGACAGCAGACGCAGAGTTCCACGCCTTCCGACGATAGCACGGTGCAGCACGAATACAATGCTATCACTAGATCTATTACAATTGCTTGCGCTATAGATAATGCCGACGACAAAGTGGAGAGTGTATTGCCGGACATGGTGGATGAGGAGCCGTCAAACAGCCACATTTCGACCGTAGACTTGCAGTGTAAATCTGTAACGTACGAGCAACCGGAAACGCAACAGTTTACGCAGCAGGTCATCGAGGAGGGATACGCGAGTGTATCCAATAGTAAAACACCCATGTGCACAATTGACATTGACTCTTGCGAGCGCGAAACGGAGATGACGAGTGACGGGAGGCCGGCGAGTCGCAGCAGCGCCGTCAACAATAATGTTGGATCACCGCGGGATCTGATAGCAATAGACGCACTGAAGGACTCCGTTCAACCCGAGCTTAATTCGGTAGAAAAATTGGAGAATTTGATAACCATAATGGAGACGGAGCTCAATAACGCTTCACTGCAGAAAGATAGTGACGCGCAAGACGATCGGGAGGGATTGGTGGACGTGAAGGAGAAAACCCCTGTGGTGGATAGGGAGGAGAGCGTGATTCACGATACGGTAGTCACGATCTCGGGCTCTCACGAGAAGGATCATGCGTTGCTCGACATACAGGAGGAGAACAAGTGGGACTCGAGCAATTACCTGGCTAGCGAACTGAGAATGTTAGAAAAAACGTGCTCGTCGCACAGAGCGGACTCGAAGATGAATGAAGCGCTGGAACGGCTGGAGCGGACTTTTCACTCggataattataagtatagtTTTTCAGCGCCCGCGTCCCCGGTCGCGAGAAGGAAGGGCACGACCCGCAGGGCCGCGCGTCGTTTATACAGATCGCGTTCGGAGCACGGCTCGTGCGAAAACCTCGGCGCGTATCGTCACCGCGTCGGCTTCGACGACGCCGCAGCCatgcacgacgacgacgacgacgacgacgacgatgacgacgacgaggacgacgaggaCGTGGACGAGGACGAGAAGATCGACGAGGAGGACAACTTTGACGAGGCGGACATGGAGATCGACGAGATCCCCAGCCCGCACACGCCTTTCGCGGACTGCGGCGTCAGGTCGCACACGCCGCTGTCCACGATCAGCGGTATTTCAGTGTTAAGAGTCAGAAAGGATCTCAGCAAGCCGTGCTCACCCACATCCATACATTCGTTTCACCACGTGGACAGCGATAGCGTAACGCACGACGAGGACAGCAACGGCGTGGGTAATATCGCGGAGAAGGATCCGATCGACTGTTCTCaggtggaggaggagaaaaTCAAGACTGATCATCAGCATCAGGAGGCGCAGGTGGCGGCGGTGTGCGGAAGCGTTGCGAAGATTCAGGAATCGAGCAGCAGCTACGCGTATCATCAGTCAGTGATAACCGAGCACATTAGTTCATTCCCCGTGATACACTCGCAGTCGTCCGTCTTGATGCACGAGTCGTACTCGATTACGACGAGCACCAAGACGCAGAACCTCCTGAATCTCTCCGAGTCGATAAATCCCACAACCAGCACCGAGTCCAGGAGCTTTCACTCCGCCAAGTCGTTGATGCCGAAGCAATCGATGGAACTGCTCAACATAAATGAGGATGCTCACGCCGGGCCAATGAATGTCTTTGAATTCGACGGACTGCAAATATTAGTTCCTAGTACGTTTATAAGTGACTCGTCTCAGAAAGCGGTGAGTGCCACGAGCCAGCAATCTATGGCGAGTAGCGAGGGTGCAATAGGTATCGACGAGGAGGTGAAGAGTATTAATATGCGTGCCGATGAGACCATGCCGCCCAGGGGCGAATTGTCGGAACAGGAGAGTAACGGATGCACGGAGCAATCTGCATGGCAGTTGTACATGGGTCAAGAATCTTCGCGCATGTCCACTTCTTACGATCTGTTGGCTCGAGAAAGCTGGGAAGAATCAGAAGGATCCGACAACGAGATCAGCGGGCCGTTGTTGGACAGTAGATCGTTGGCCACGCACTTTACTTCGAGTCTGTTTCTGGATCGCGACCGGAAGACACCAACCAAACGAACATTCAAGTGTTCCCACTGTAGCGAAGTGTTTGATTGTCCGAAGGAACGTAGAGTTCATAGCACAACGGTGCACAAGGATGCGATGCCCAGTAGCAGTAGAGACCAGTTGGACCAGCCGGAGGTGAAGGACATCAAGTTGCTGGACAGTCGCATGAACATGTTCGACGATATATTCATGCCGAGTATACACATGCAACAACACATGTACCATCAGCAGCCGCTCTTGCACCAGCTGCAGCCACCGTCGCAGCCGGAGTCGGACGGCCTGACGAAGGCCGAGGCCGACCAGAAGATCGGCGAGAATCTGGTGATACCGTCGAACATCGAGGTGATTTGCACGATTTGCAATCAGCGATTCAACAGCGAGAAGTCTCTGCAGGCGCATCATCGGCGCATGCATATCGCCGACGTGAACAAACGCATACGCGAGACCGCCAAGTGCCAGATATGCAACGAGGAATTCCCGTCGGTGTTCCTGTTCAACGCCCACCTGAAGATACATCCGTTGGAGTGCGGGCAGTGCGGCAAGTATTTTTACCGCAAGCAGAACTTCAAGCTTCACATGAAGCGCCATTTGGGCATCAAGCCGTTCCCATGTACCGTGTGCGACAAGGCGTTCCTCACCAAGCAGAAGCTGGAGGAGCACACCAACGGCCACACCGGCAACGCGCCCGTCAGGTGTAGCCTGTGCAACGAGACCTTCCGCCGATACTCGAATCTGACCCAACACAAGAACAGGCATCACCTCAACATCAAGAAGAAGCTCAAGGACTACATATGCCACTGCGGCGAGGTGTTCCACACGAAGAAGAAGCTCGCCTGGCACAAGGAGACGCACGACGAGAAGCCGAAGGCGTGCACGTACTGCAACGAGCGGTTCATCCACATGGCCAGCCTGACGCGTCACATGCGTCGCGCTCACAATCGCCGATTCGTCCCCGACGCCCAGCGCGAGAGCGAGAACGTCGAGTGCCCGATCTGCAAGTGCATCTACCTGCGATCGTCGCTGGCGGTGCACATGCGCGTGCACAACGGCGAGCGGCCGTACGAGTGCCAGGTCTGCTCCAAGGCGTTCAGCACCAAGTGGAACCTGCAGCTGCACAAGTGGACGCACGCGGCGCGCAGCACCAAGCCGTTCAAGTGTAATCAGTGCAGCGCGGCGTTCTACCGTCACAGCGATTACACGGCCCACATGAATTCCCATCGGAACGTGCGGCCGTACACGTGCAACTACTGCGGCGCGCAGTTCATCCGCAAGTACAACTGCCTGCGGCACGTGAAGGAGCACGAGGAGAACAAGGCGTACACGTGCGACGTCTGCAACAAGACCTTCCACCGCTCGTACTATCTCAAGGAGCATCTGCGAGTGCACTCGGGCGCGCGGCCGTACACGTGTCACATCTGCGGCAAGTCCAGCGGCACCAAGTCCAATCACAACAAGCACGTGCGAATCCATCACGCCCGCGAGCCTGTAAATACCGAGAATTGA
Protein Sequence
MELNGTGTPVGAVACPVCTLYLREGISLQKHLDTHPKEQVIDALIKASASSSQTQQQQQQQQQLQQQQQPQQTLSASSSATSLPLSLQPQAALQTPTSIQSPQASSQVSQNAQISTHSPYPVGPIFECPPISTMMPPQFTSFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQIPTVQMISPVAAIPGATTRVRPVVTMAGESNVRTLTVPVNSPEPKQILPEILPDAEPESGQIMPDVSLSASPVLQSEDASIRAREESDSSGTLPIDHRGQQTQSSTPSDDSTVQHEYNAITRSITIACAIDNADDKVESVLPDMVDEEPSNSHISTVDLQCKSVTYEQPETQQFTQQVIEEGYASVSNSKTPMCTIDIDSCERETEMTSDGRPASRSSAVNNNVGSPRDLIAIDALKDSVQPELNSVEKLENLITIMETELNNASLQKDSDAQDDREGLVDVKEKTPVVDREESVIHDTVVTISGSHEKDHALLDIQEENKWDSSNYLASELRMLEKTCSSHRADSKMNEALERLERTFHSDNYKYSFSAPASPVARRKGTTRRAARRLYRSRSEHGSCENLGAYRHRVGFDDAAAMHDDDDDDDDDDDDEDDEDVDEDEKIDEEDNFDEADMEIDEIPSPHTPFADCGVRSHTPLSTISGISVLRVRKDLSKPCSPTSIHSFHHVDSDSVTHDEDSNGVGNIAEKDPIDCSQVEEEKIKTDHQHQEAQVAAVCGSVAKIQESSSSYAYHQSVITEHISSFPVIHSQSSVLMHESYSITTSTKTQNLLNLSESINPTTSTESRSFHSAKSLMPKQSMELLNINEDAHAGPMNVFEFDGLQILVPSTFISDSSQKAVSATSQQSMASSEGAIGIDEEVKSINMRADETMPPRGELSEQESNGCTEQSAWQLYMGQESSRMSTSYDLLARESWEESEGSDNEISGPLLDSRSLATHFTSSLFLDRDRKTPTKRTFKCSHCSEVFDCPKERRVHSTTVHKDAMPSSSRDQLDQPEVKDIKLLDSRMNMFDDIFMPSIHMQQHMYHQQPLLHQLQPPSQPESDGLTKAEADQKIGENLVIPSNIEVICTICNQRFNSEKSLQAHHRRMHIADVNKRIRETAKCQICNEEFPSVFLFNAHLKIHPLECGQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLEEHTNGHTGNAPVRCSLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRESENVECPICKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN