Basic Information

Insect: Harpagoxenus sublaevis
Gene Symbol: ZFX
Assembly: GCA_030770355.1
Location: JASTWR010000014.1:1831588-1836834[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.1 3.7e+02 3.3 0.1 3 23 15 35 14 35 0.94

2 15 3.9 7.2e+02 2.4 3.8 1 23 963 986 963 986 0.81

3 15 0.00016 0.029 16.2 1.9 3 23 1075 1096 1073 1096 0.96

4 15 0.0035 0.64 12.0 0.2 2 23 1109 1130 1109 1130 0.98

5 15 2.2e-05 0.004 18.9 2.3 2 23 1133 1154 1132 1154 0.97

6 15 0.0028 0.5 12.3 0.3 1 23 1160 1182 1160 1182 0.96

7 15 5.4e-05 0.0098 17.7 4.3 2 23 1189 1210 1188 1211 0.95

8 15 0.14 25 7.0 3.7 5 23 1224 1242 1223 1242 0.97

9 15 2.8e-05 0.005 18.6 1.5 3 23 1249 1270 1248 1270 0.97

10 15 0.013 2.3 10.2 0.3 2 23 1286 1306 1285 1306 0.97

11 15 8.3e-05 0.015 17.1 0.7 1 20 1312 1331 1312 1334 0.92

12 15 0.0001 0.019 16.8 2.7 1 23 1342 1364 1342 1364 0.99

13 15 0.0029 0.53 12.2 3.2 1 23 1370 1392 1370 1392 0.97

14 15 5.3e-06 0.00095 20.9 3.9 1 23 1398 1420 1398 1420 0.99

15 15 0.0018 0.33 12.9 6.3 1 23 1426 1448 1426 1449 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.1	3.7e+02	3.3	0.1	3	23	15	35	14	35	0.94
2	15	3.9	7.2e+02	2.4	3.8	1	23	963	986	963	986	0.81
3	15	0.00016	0.029	16.2	1.9	3	23	1075	1096	1073	1096	0.96
4	15	0.0035	0.64	12.0	0.2	2	23	1109	1130	1109	1130	0.98
5	15	2.2e-05	0.004	18.9	2.3	2	23	1133	1154	1132	1154	0.97
6	15	0.0028	0.5	12.3	0.3	1	23	1160	1182	1160	1182	0.96
7	15	5.4e-05	0.0098	17.7	4.3	2	23	1189	1210	1188	1211	0.95
8	15	0.14	25	7.0	3.7	5	23	1224	1242	1223	1242	0.97
9	15	2.8e-05	0.005	18.6	1.5	3	23	1249	1270	1248	1270	0.97
10	15	0.013	2.3	10.2	0.3	2	23	1286	1306	1285	1306	0.97
11	15	8.3e-05	0.015	17.1	0.7	1	20	1312	1331	1312	1334	0.92
12	15	0.0001	0.019	16.8	2.7	1	23	1342	1364	1342	1364	0.99
13	15	0.0029	0.53	12.2	3.2	1	23	1370	1392	1370	1392	0.97
14	15	5.3e-06	0.00095	20.9	3.9	1	23	1398	1420	1398	1420	0.99
15	15	0.0018	0.33	12.9	6.3	1	23	1426	1448	1426	1449	0.96

Sequence Information

Coding Sequence: ATGGAGCTGAACGGTGCGGGAACGCCCGTCGGGGCCGTGGCCTGTCCCGTGTGTACCCTGTATCTGCGCGAGGGCATCAGTCTGCAGAAGCATCTGGACACTCACCCCAAGGAACAGGTTATAGAGGCCCTCATCAAAGCCAGCGCCTCCTCGTCACACacccagcagcagcagcagcagcagcaagcTCTATCAGCATCAGCAGCAACGTCATTACCATTATCGCTGCACCCGCAGGCTGCTGCTCTTCATACCTCTACCCCCATCCAGGCGCCCCAAGCGTCCACCAATGTATCGCATCAGAACGCGCACATTTCCACTCACTCTCCGTATCCCGTAGGACCCATCTTCGAATGTCCGCCCATAAGCAACATGATGCCGCCGCAGTTCACCTCATTCAGCTATCAGCAATTCGTGAACAATGGGACCATGATGATACCGCAGTACGCGATGGCGCCGCAAGCGAATCAGATGATGCAGATGCTGTACAATCCATATGGTATGTACCAACAACAAGTGCCCACCGTCCAAATGATCTCACCAGTTGCAGCTATTCCCGGCGCGACGGCGTCGACGAGGGTCATCCGACCGGTGGCCACCATGGCCACCGGGGAGAGCAACGTCAGAACCCTGACGGTTCCTGTAAATAGTGCCGAGCCGAAGCAGATTCTGCCAGAGATTTTGCCGGATGCGGAGCCCGAGTCCGGGCAAGTTATACCGGACGTGGCCATCTCGGCCTCGTCTGTGCTGCAGAATGAGGATACATCCATCAGAGGTAGGCAGGAGAGCGACAGCAGCGCGCTGTTGATTGATCACCGTGGACAGCAGACCCAGAGTTCTGCATCTCCCGGTGAAAGCGCGATACAACACGAGTACAATGCTATTCCTAGGTCTATTACAATTGCTTGCGCTATAGATAACGCAGATGACAAGGTGGAGAGTGTATTGCCGGACATTGTGGACGAGGAGCCGTCAATGAACAGCACCACGGACCTGCGGCGTAAATCCGTGACGTACGAGCAACCGGAGACACAACAGTTTACGCAACAGGTTATCGACGAGGGATACGTGAGTGTATCCAATAGAAAAACAATCAATGAGACAGCCGAGATTGACTCCGTGGCTTGCGGGCGCGAACCAGAAGTGTCGAGTAACGAAGGATCCGCGAGTCCTAGCAGCAGCATCAACGTCGGATCACCGCGGGATCTGTTAGCGATAGACGCGTTGAAGGACTCTGTCCAACCCGAGCTTAACTCGGCAGAAAAATTGAAGAATTTGATAACTATAATGGAAACGGAGCTCAATAATACGTCGCTTCAGAAGGAAAGTGATACGCCAAACGATCAGGAGAGACTGATGGACACGCAGGAGGAAGCCGCCGCGGTGGACAGGGAGGAGAGCGTGATTCACGACACGGTGGTCACTATCCCGCCGGGCTCCCACGAGAAGGATCTCATATTGCCCGACGCACAGGAGGAGAACAGGTGGGACTCGAGCAATTACATAGGTAACGAACTGAGAACGCCGGAGAAAACTTGTGATCTGTCGTACAGAGTAGACGCTTCGAAGATGAACGAGCGACTGGAAATACCGGAGAGAACTTTTCATTCGGATAATTATAAGTATAGTTTATCAGCGCCCACGTCCCCGGTCGTGAGACGGAAGAGCCGCAGAGTCGCGCGCCGCTACAGTTTGCGATCGGAGCACGGATCGTGCGAAAATCTCAGCGTGTATCGTCACCGTGGCTGTTTCGACGACGTATCAatgcacgacgacgacgatggcgaCGATGACGGCGAGGACGACGAGGACGTTGACGATCTCGAGAAGATCGAAGAGGATGATAATTTCGACGATGCGGACATGGAGATCGACCAGATTCCCAGTCCGCACACGCCTTTCGCGGACTGCGGTGTCAGATCGCACACGCCGCTGTCCACGATCAGCGGCATTTCCGTGTTAAGAGTTAGGAAAGATCTCAGCAAGCCGTGCTCACCCACGTCCATGCATTCGTTTCATCATGCGGACAGCGATAGCGTGACACACGACGAGGACAGCAACGGCGTAAGTAACACAGCGGAGAAGGATCCAATCGATTGTTCTCAGGTGGACGAGGAGAAAGTCAAGACTGATCAGCAACAGGAGACGCAGGTGTCGGTGTGCGGTAGCGTCGCGAAGGTTCAGGAGTCGACGAGCAGCAGTTACGCGTACCATCAATCAGTGATAACCGAACACATCAGTTCATTCCCCGTAATAAACTCGCAGTCGTCCGTCTTGATGCACGAGTCGTATTCCATCACGACGAGCACCAAGACGCAAAACCTCCTGAATCTCTCCGAATCGATAAATCCGACAACCAGCACCGAATCCAGAAGCTTTCACTCTGCCAAGTCGTCGACGCCGAAGCAATCGATGGAACTGCTCAACATAAATGAAGATGCTCACGCCGGGCCAATGAATGTCTTTGAATTCGACGGACTGCAAATCCTGCAATTAGTTCCTAGTTCGTTTATAAGTGACTCGTCCCAGAAAGCGGTGAGTGCGACCAGCCAGCAGTCTATGGCGAGTAGCGAGGGTGCAATAGGTATCGACGAGGAGGTGAAGAGTATTAATATGCGTGCCGACGAGACCATGCCGCCTAGGGGTGAATTGTCGGAACAAGAGAGTAATGGATGTACGGAGCAGTCTGCATGGCAGTTGTACATGGGTCAAGAATCGTCGCGTATGTCCACCTCTTACGATCTGTTGGCTCGAGAAAGCTGGGAAGAATCGGAGGGATCCGACAACGAGATCAGCGGGCCGTTGTTGGACAGTAGATCGTTAGCCACGCACTTCACTTCGAGTCTGTTTCTGGATCGTGACCGAAAGACACCGACCAAACGAACATTTAAGTGTTCCCATTGTAGCGAAGTGTTTGATTGCCCGAAAGAACGTAGAGTTCATAGCACAACGGTACACAAGGATGCGATGCCCAGTAGCAGTAGAGACCAGCTGGATCAGTCGGAGATGAAGGACATCAAGTTGCTGGACAATCGCATGAACATGTTGGACGATATATTCATGCCGAGTATACACATGCAGCAGCACATGTACCATCATCAACAGCCGCTCTTGCACCAACTACAGCCACCGTCGCAGGCTGAATCGGACGGCCTGACGAAGGCCGAGGCCGACCATAAGATCAGCGAGAATATGGTGATACCGTCGAACGTCGAGGTGATCTGCACAATATGCAATCAGCGTTTCAATAGCGAGAAGTCCCTGCAGGCGCATCATCGGCGCATGCATATCGCCGACGTGAACAAACGCATACGCGAGACCGCCAAGTGCCAGATATGCAACGAGGAATTCCCGTCGGTGTTCCTGTTCAACGCCCATCTGAAGATACACCCGTTAGAGTGCGGACAGTGCGGCAAGTATTTTTATCGTAAGCAGAACTTTAAGCTCCACATGAAACGTCACCTGGGCATCAAGCCGTTCCCGTGTACCGTGTGCGACAAGGCGTTCCTCACCAAGCAGAAGCTGGAGGAGCACACCAACGGCCACACCGGCAACGCGCCCGTCAGGTGTAGTCTGTGCAACGAGACCTTCCGCAGATACTCGAATCTGACCCAGCACAAAAACAGGCATCACCTCAACATCAAGAAGAAGCTCAAGGACTACATATGCCACTGCGGCGAGGTATTCCACACGAAGAAGAAACTCGCCTGGCATAAGGAGACGCACGACGAGAAGCCCAAGGCGTGCACGTACTGCAACGAGCGATTCATCCACATGGCCAGTCTGACGCGTCACATGCGTCGCGCCCACAATCGCCGATTCGTTCCCGACGCTCAGCGCGAGAGCGAGAACGTCGAGTGCCCGATCTGCAAGTGCATCTACCTGCGATCATCCCTGGCGGTGCATATGCGCGTGCACAACGGCGAGCGGCCGTACGAATGTCAAGTATGTTCCAAGGCGTTCAGCACCAAGTGGAATCTGCAGCTGCACAAGTGGACGCACGCGGCGCGCAGCACCAAGCCGTTCAAATGCAATCAGTGCAGCGCGGCGTTCTACCGTCACAGCGATTACACGGCCCACATGAACTCCCATCGGAACGTGCGGCCGTACACGTGCAACTACTGCGGCGCGCAGTTCATCCGCAAGTACAACTGCCTGCGACACGTGAAGGAGCACGAGGAGAACAAGGCGTACACGTGCGACGTGTGCAACAAGACCTTCCACCGCTCGTACTATCTCAAGGAGCACCTGCGGGTGCATTCGGGCGCGCGGCCGTACACGTGTCACATCTGCGGCAAGTCCAGCGGCACCAAGTCCAATCACAACAAGCACGTGCGAATTCATCACGCGCGCGAGCCTGTAAATACCGAGAATTGA
Protein Sequence: MELNGAGTPVGAVACPVCTLYLREGISLQKHLDTHPKEQVIEALIKASASSSHTQQQQQQQQALSASAATSLPLSLHPQAAALHTSTPIQAPQASTNVSHQNAHISTHSPYPVGPIFECPPISNMMPPQFTSFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQVPTVQMISPVAAIPGATASTRVIRPVATMATGESNVRTLTVPVNSAEPKQILPEILPDAEPESGQVIPDVAISASSVLQNEDTSIRGRQESDSSALLIDHRGQQTQSSASPGESAIQHEYNAIPRSITIACAIDNADDKVESVLPDIVDEEPSMNSTTDLRRKSVTYEQPETQQFTQQVIDEGYVSVSNRKTINETAEIDSVACGREPEVSSNEGSASPSSSINVGSPRDLLAIDALKDSVQPELNSAEKLKNLITIMETELNNTSLQKESDTPNDQERLMDTQEEAAAVDREESVIHDTVVTIPPGSHEKDLILPDAQEENRWDSSNYIGNELRTPEKTCDLSYRVDASKMNERLEIPERTFHSDNYKYSLSAPTSPVVRRKSRRVARRYSLRSEHGSCENLSVYRHRGCFDDVSMHDDDDGDDDGEDDEDVDDLEKIEEDDNFDDADMEIDQIPSPHTPFADCGVRSHTPLSTISGISVLRVRKDLSKPCSPTSMHSFHHADSDSVTHDEDSNGVSNTAEKDPIDCSQVDEEKVKTDQQQETQVSVCGSVAKVQESTSSSYAYHQSVITEHISSFPVINSQSSVLMHESYSITTSTKTQNLLNLSESINPTTSTESRSFHSAKSSTPKQSMELLNINEDAHAGPMNVFEFDGLQILQLVPSSFISDSSQKAVSATSQQSMASSEGAIGIDEEVKSINMRADETMPPRGELSEQESNGCTEQSAWQLYMGQESSRMSTSYDLLARESWEESEGSDNEISGPLLDSRSLATHFTSSLFLDRDRKTPTKRTFKCSHCSEVFDCPKERRVHSTTVHKDAMPSSSRDQLDQSEMKDIKLLDNRMNMLDDIFMPSIHMQQHMYHHQQPLLHQLQPPSQAESDGLTKAEADHKISENMVIPSNVEVICTICNQRFNSEKSLQAHHRRMHIADVNKRIRETAKCQICNEEFPSVFLFNAHLKIHPLECGQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLEEHTNGHTGNAPVRCSLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRESENVECPICKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01523563;
90% Identity: iTF_00885358;
80% Identity: -