Basic Information

Insect: Aphaenogaster miamiana
Gene Symbol: ZFX
Assembly: GCA_003063725.1
Location: NJRN01000311.1:1578-6708[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.7 1.9e+02 3.3 0.1 3 23 15 35 14 35 0.94

2 15 3.2 3.7e+02 2.4 3.8 1 23 959 982 959 982 0.81

3 15 0.00013 0.015 16.2 1.9 3 23 1071 1092 1069 1092 0.96

4 15 0.0029 0.33 12.0 0.2 2 23 1105 1126 1105 1126 0.98

5 15 1.8e-05 0.0021 18.9 2.3 2 23 1129 1150 1128 1150 0.97

6 15 0.0023 0.26 12.3 0.3 1 23 1156 1178 1156 1178 0.96

7 15 4.4e-05 0.005 17.7 4.3 2 23 1185 1206 1184 1207 0.95

8 15 0.11 13 7.0 3.7 5 23 1220 1238 1219 1238 0.97

9 15 2.3e-05 0.0026 18.6 1.5 3 23 1245 1266 1244 1266 0.97

10 15 0.01 1.2 10.2 0.3 2 23 1282 1302 1281 1302 0.97

11 15 6.8e-05 0.0078 17.1 0.7 1 20 1308 1327 1308 1330 0.92

12 15 8.5e-05 0.0097 16.8 2.7 1 23 1338 1360 1338 1360 0.99

13 15 0.0024 0.27 12.2 3.2 1 23 1366 1388 1366 1388 0.97

14 15 4.3e-06 0.00049 20.9 3.9 1 23 1394 1416 1394 1416 0.99

15 15 0.0015 0.17 12.9 6.3 1 23 1422 1444 1422 1445 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.7	1.9e+02	3.3	0.1	3	23	15	35	14	35	0.94
2	15	3.2	3.7e+02	2.4	3.8	1	23	959	982	959	982	0.81
3	15	0.00013	0.015	16.2	1.9	3	23	1071	1092	1069	1092	0.96
4	15	0.0029	0.33	12.0	0.2	2	23	1105	1126	1105	1126	0.98
5	15	1.8e-05	0.0021	18.9	2.3	2	23	1129	1150	1128	1150	0.97
6	15	0.0023	0.26	12.3	0.3	1	23	1156	1178	1156	1178	0.96
7	15	4.4e-05	0.005	17.7	4.3	2	23	1185	1206	1184	1207	0.95
8	15	0.11	13	7.0	3.7	5	23	1220	1238	1219	1238	0.97
9	15	2.3e-05	0.0026	18.6	1.5	3	23	1245	1266	1244	1266	0.97
10	15	0.01	1.2	10.2	0.3	2	23	1282	1302	1281	1302	0.97
11	15	6.8e-05	0.0078	17.1	0.7	1	20	1308	1327	1308	1330	0.92
12	15	8.5e-05	0.0097	16.8	2.7	1	23	1338	1360	1338	1360	0.99
13	15	0.0024	0.27	12.2	3.2	1	23	1366	1388	1366	1388	0.97
14	15	4.3e-06	0.00049	20.9	3.9	1	23	1394	1416	1394	1416	0.99
15	15	0.0015	0.17	12.9	6.3	1	23	1422	1444	1422	1445	0.96

Sequence Information

Coding Sequence: ATGGAGCTCAACGGTGCGGGAACGCCCGTCGGGGCCGTGGCCTGTCCTGTGTGCACCCTGTATTTGCGCGAGGGCATCAGTCTGCAGAAGCATCTGGACACTCATCCCAAGGAACAGGTTATAGATGCTCTCATCAAAGCCAGCGCCTCCTCGTTACAgtcgcagcagcagcaacagcaacaacagcagcagcagcaagctTTACCAGCATCAGCAGCAACGTCACTACCGTTATCATTGCAGCCGCAAGCTGCGCTTCAGACCCCTACCTCCATCCAGGCGCCCCAAGCGTCCACCCAAGTCTCGCAGAACACGCACATTTCTACTCACTCTCCATATCCCGTAGGACCCATCTTCGAATGTCCGCCCATAAACACCATGATGCCGCCGCAGTTCACCTCATTCAGCTATCAGCAATTCGTGAACAATGGGACCATGATGATACCGCAGTACGCGATGGCGCCACAAGCCAATCAGATGATGCAGATGCTGTACAATCCATACGGTATGTACCAACAGCAAATACCCACCGTCCAAATGATCTCACCAGTTGCAGCTATTCCTGGCGCGACGACGAGGGTGCGACCAGTGGTCACTATGGCTGGGGAGAGCAACGTCAGAACCCTGACGGTTCCTGTAAATAGTCCCGAGCCGAAGCAGATTCTGCCTGAAATTTTACCGGAGACGGAGCCCGAATCCGGCCAAGTTATACCGGATGTGAGCCTCTCAGTCTCGCCTGTACTACAAAATGAGGATACATCCGTCAGAGCAAGGGAGGAGAGCGCCAGCAGTGCGCTGCCAATTGATCATCGAGGACAACAGACACAGAGCTCTGCATCTCCTGGTGATAGCACGGTGCAGCATGAGTATAATGCTATTCCTAGATCTATTACAATTGCTTGCGCTATAGATAATACTGATGATAAAGTGGAGAGTGTATTGCCAGACATGATGGACGAGGAGCCATCAAGCAACATTTCGACGGACTTACAATGTAAATCTGTAACGTATGAGCAACCAGAAACACAACAGTTTACACAACAAGTTATCGACGAAGGATACGTAAGTGTATCCAATAGGAAAACACCCAATGGGATAGCTGAAATTGACTCCATGATTTGCGAGCGTGAATCGGAAGTGATAAGTGATGAAAGGCCCACAAGTCGCAGCAGCAACGTTGCATCACCGCGGGATCTGATTGCAATAGACGCATTGAAAGATTCTGTCCAACCCGAGCTTAACTCGgtagaaaaattggaaaatttgatAACTATAATGGAGACGGAACTCAATAACGCTTCGCTTCAGAAAGAAAGTAATACACAAAACGATCAGGAGAGATTGGTGGACACGAAGGAGAAAACTACCGTAATAGATAGGGAGGAGAGCGTGATACACGATACAGTAGTCACGATCCCGGGCTCCCATGAAAAGGATCACATATTGCCCGACATACAGGAAGAGAACAAGTGGTGCTCGAGCAATTACGTAGCTAACGAACTGAGAACGCTAGAAAAAACTTGTAGTTTGTCATACAAAGTAGACTGCGCGAAAATAAATGAAGCACTGGAAAGATTGGAGAGACTGGAAAGAACTTTTCATTCGACTAATTATAAGTATAGTTTTTCAGCGCCCGCGTCCCCGGTCCCGAGAAGGAAGAACCGCAGGATCGTGCGTCGTTACAGCTCGCGATCGGAGCATGGATCGTGCGAAAATCTCAGCGCGTATCGTCATCGCGTCGGTTTCGACGCGGCCATGCatgaggacgacgacgacgatgacgacgacgacgatgatgacgaggaCGTGGACGAGGATGAGAAGATCGACGAGGAGGATAATTTCGATGAGGCGGACATGGAGATCGACGAGATCCCCAGTCCGCACACACCTTTCGCGGATTGCGGCGTCAGATCGCACACGCCGTTGTCCACGATCAGCGGCATTTCTGTATTAAGAGTTAGAAAGGATCTCAGCAAACCATGTTCACCCACGTCCATGCATTCGTTTCATCACGTGGACAGCGATAGCGTAACTCATGACGAGGACAGTAACGGCGTAGGTAACACCGCAGAGAAGGATCCAATCGACTGTTCTCAGGTGGAGGAGGAGAAAATCAAGACTGATCATCAGCAGCAGGAGACGCAGGTGGCGGTGTGCGGAAGTGTCGCAAAGGTTCAGGAATCGAGCAGTAGCTACGCGTACCATCAATCAGTGATAACCGAACACATTAGTTCATTCCCCGTGATACACTCGCAGTCGTCCGTCTTGATGCACGAGTCGTATTCCATTACGACGAGCACCAAGACGCAGAACCTCTTGAATCTCTCCGAGTCAATAAATCCCACAACCAGCACCGAATCCAGAAGCTTTCACTCTGCCAAGTCGTTGATGCCGAAGCAATCGATGGAACTGCTCAACATAAATGAAGATGCTCACGCCGGGCCAATGAATGTCTTTGAATTCGACGGACTGCAAATATTAGTTCCTAGTACGTTTATAAGTGACTCGTCCCAGAAAGCGGTGAGTGCGACCAGCCAGCAATCTATGGCGAGTAGCGAGGGTGCAATAGGTATCGACGAGGAGGTGAAGAGTATTAATATGCGTGCCGATGAGACCATGCCGCCTAGGGGCGAATTGTCGGAACAAGAGAGTAATGGATGCACGGAGCAGTCTGCATGGCAGTTGTACATGGGTCAAGAATCTTCGCGCATGTCCACCTCTTACGATCTGTTGGCTCGAGAAAGCTGGGAAGAATCAGAAGGATCTGACAACGAGATCAGCGGACCGTTGTTGGATAGTAGATCGTTGGCCACGCACTTTACTTCGAGTCTGTTTCTGGATCGGGACCGAAAGACACCGACTAAACGAACATTCAAGTGTTCCCACTGTAGCGAAGTGTTTGATTGTCCAAAGGAGCGTAGAGTTCATAGCACAACGGTGCACAAGGATGCGATGCCCAGTAGCAGTAGAGATCAGTTGGATCAGCCAGAAGTAAAGGACATCAAGTTGCTGGACAGTCGCATGAATATGTTTGACGATATATTCATGCCGAGTATACACATGCAACAACACATGTACCATCATCAGCAGCCGCTCTTGCACCAGCTGCAGCCACCGTCGCAGCCTGGATCGGATGGCCTGACAAAGGCCGAGGCCGACCAGAAAATCGGCGAGAATCTAGTAATACCGTCGAACATCGAGGTGATCTGTACCATATGCAATCAGCGATTCAATAGCGAGAAATCCCTACAGGCGCATCACCGGCGCATGCATATCGCCGACGTGAACAAACGCATACGCGAGACCGCAAAGTGTCAGATATGCAATGAGGAATTTCCATCGGTATTCCTATTTAATGCTCATCTGAAGATACACCCGTTAGAGTGCGGACAGTGCGGCAAGTATTTCTACCGGAAGCAGAACTTCAAGCTCCACATGAAACGTCACCTGGGCATCAAGCCGTTCCCGTGTACCGTGTGCGACAAGGCATTCCTTACCAAGCAGAAACTGGAGGAGCACACCAACGGCCACACCGGCAACGCACCCGTCAGGTGTAGTTTGTGCAATGAGACCTTCCGTAGATATTCGAATCTGACACAGCACAAAAACAGACATCATCTCAACATCAAGAAGAAGCTCAAGGATTACATATGCCACTGTGGCGAGGTGTTTCACACGAAGAAGAAGCTCGCCTGGCACAAAGAGACTCACGACGAGAAGCCCAAGGCGTGCACGTACTGCAACGAGCGATTTATCCACATGGCCAGCCTGACGCGTCACATGCGTCGCGCCCACAATCGCCGCTTCGTTCCCGACGCTCAGCGCGAGAGCGAGAATGTCGAGTGCCCGATCTGCAAGTGTATCTACCTGCGATCGTCGCTAGCGGTGCATATGCGCGTGCACAACGGCGAGCGGCCGTACGAGTGTCAGGTCTGCTCCAAGGCGTTCAGCACCAAATGGAACCTGCAGCTGCACAAGTGGACACACGCGGCGCGCAGTACCAAGCCCTTCAAATGTAATCAGTGCAGCGCGGCGTTCTACCGTCACAGCGATTACACGGCGCACATGAATTCCCATCGGAACGTGCGGCCGTACACGTGCAACTactgcggcgcgcagttcatcCGCAAGTACAACTGCCTGCGGCACGTGAAGGAGCACGAAGAGAACAAGGCATACACGTGCGACGTGTGCAATAAGACCTTCCACCGCTCGTACTATCTCAAGGAGCACCTGCGGGTGCACTCGGGCGCGCGGCCGTACACGTGTCACATCTGCGGCAAGTCCAGCGGCACCAAATCCAATCACAACAAGCACGTGCGAATCCATCACGCGCGCGAGCCTGTAAATACCGAGAATTGA
Protein Sequence: MELNGAGTPVGAVACPVCTLYLREGISLQKHLDTHPKEQVIDALIKASASSLQSQQQQQQQQQQQQALPASAATSLPLSLQPQAALQTPTSIQAPQASTQVSQNTHISTHSPYPVGPIFECPPINTMMPPQFTSFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQIPTVQMISPVAAIPGATTRVRPVVTMAGESNVRTLTVPVNSPEPKQILPEILPETEPESGQVIPDVSLSVSPVLQNEDTSVRAREESASSALPIDHRGQQTQSSASPGDSTVQHEYNAIPRSITIACAIDNTDDKVESVLPDMMDEEPSSNISTDLQCKSVTYEQPETQQFTQQVIDEGYVSVSNRKTPNGIAEIDSMICERESEVISDERPTSRSSNVASPRDLIAIDALKDSVQPELNSVEKLENLITIMETELNNASLQKESNTQNDQERLVDTKEKTTVIDREESVIHDTVVTIPGSHEKDHILPDIQEENKWCSSNYVANELRTLEKTCSLSYKVDCAKINEALERLERLERTFHSTNYKYSFSAPASPVPRRKNRRIVRRYSSRSEHGSCENLSAYRHRVGFDAAMHEDDDDDDDDDDDDEDVDEDEKIDEEDNFDEADMEIDEIPSPHTPFADCGVRSHTPLSTISGISVLRVRKDLSKPCSPTSMHSFHHVDSDSVTHDEDSNGVGNTAEKDPIDCSQVEEEKIKTDHQQQETQVAVCGSVAKVQESSSSYAYHQSVITEHISSFPVIHSQSSVLMHESYSITTSTKTQNLLNLSESINPTTSTESRSFHSAKSLMPKQSMELLNINEDAHAGPMNVFEFDGLQILVPSTFISDSSQKAVSATSQQSMASSEGAIGIDEEVKSINMRADETMPPRGELSEQESNGCTEQSAWQLYMGQESSRMSTSYDLLARESWEESEGSDNEISGPLLDSRSLATHFTSSLFLDRDRKTPTKRTFKCSHCSEVFDCPKERRVHSTTVHKDAMPSSSRDQLDQPEVKDIKLLDSRMNMFDDIFMPSIHMQQHMYHHQQPLLHQLQPPSQPGSDGLTKAEADQKIGENLVIPSNIEVICTICNQRFNSEKSLQAHHRRMHIADVNKRIRETAKCQICNEEFPSVFLFNAHLKIHPLECGQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLEEHTNGHTGNAPVRCSLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRESENVECPICKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01523563;
90% Identity: iTF_00385833; iTF_00126187; iTF_00127681; iTF_01523563; iTF_01421744; iTF_01423857; iTF_01355641; iTF_01354804; iTF_01405978; iTF_01407611; iTF_01409418; iTF_01408504; iTF_00126941; iTF_01406750; iTF_00129216; iTF_00129958; iTF_01520487;
80% Identity: -