Basic Information

Insect: Temnothorax americanus
Gene Symbol: ZFX
Assembly: GCA_030770215.1
Location: JASTWO010001210.1:119404-124571[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2 3.1e+02 3.3 0.1 3 23 15 35 14 35 0.94

2 15 3.9 6e+02 2.4 3.8 1 23 967 990 967 990 0.81

3 15 0.00012 0.019 16.6 1.5 3 23 1079 1100 1077 1100 0.96

4 15 0.0051 0.79 11.4 0.2 2 23 1113 1134 1113 1134 0.98

5 15 2.2e-05 0.0034 18.9 2.3 2 23 1137 1158 1136 1158 0.97

6 15 0.0027 0.42 12.3 0.3 1 23 1164 1186 1164 1186 0.96

7 15 5.3e-05 0.0082 17.7 4.3 2 23 1193 1214 1192 1215 0.95

8 15 0.14 21 7.0 3.7 5 23 1228 1246 1227 1246 0.97

9 15 2.7e-05 0.0042 18.6 1.5 3 23 1253 1274 1252 1274 0.97

10 15 0.012 1.9 10.2 0.3 2 23 1290 1310 1289 1310 0.97

11 15 8.3e-05 0.013 17.1 0.7 1 20 1316 1335 1316 1338 0.92

12 15 0.0001 0.016 16.8 2.7 1 23 1346 1368 1346 1368 0.99

13 15 0.0029 0.44 12.2 3.2 1 23 1374 1396 1374 1396 0.97

14 15 5.2e-06 0.0008 20.8 3.9 1 23 1402 1424 1402 1424 0.99

15 15 0.0018 0.28 12.9 6.3 1 23 1430 1452 1430 1453 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2	3.1e+02	3.3	0.1	3	23	15	35	14	35	0.94
2	15	3.9	6e+02	2.4	3.8	1	23	967	990	967	990	0.81
3	15	0.00012	0.019	16.6	1.5	3	23	1079	1100	1077	1100	0.96
4	15	0.0051	0.79	11.4	0.2	2	23	1113	1134	1113	1134	0.98
5	15	2.2e-05	0.0034	18.9	2.3	2	23	1137	1158	1136	1158	0.97
6	15	0.0027	0.42	12.3	0.3	1	23	1164	1186	1164	1186	0.96
7	15	5.3e-05	0.0082	17.7	4.3	2	23	1193	1214	1192	1215	0.95
8	15	0.14	21	7.0	3.7	5	23	1228	1246	1227	1246	0.97
9	15	2.7e-05	0.0042	18.6	1.5	3	23	1253	1274	1252	1274	0.97
10	15	0.012	1.9	10.2	0.3	2	23	1290	1310	1289	1310	0.97
11	15	8.3e-05	0.013	17.1	0.7	1	20	1316	1335	1316	1338	0.92
12	15	0.0001	0.016	16.8	2.7	1	23	1346	1368	1346	1368	0.99
13	15	0.0029	0.44	12.2	3.2	1	23	1374	1396	1374	1396	0.97
14	15	5.2e-06	0.0008	20.8	3.9	1	23	1402	1424	1402	1424	0.99
15	15	0.0018	0.28	12.9	6.3	1	23	1430	1452	1430	1453	0.96

Sequence Information

Coding Sequence: ATGGAGCTCAACGGTGCGGGTACGCCCGTCGGGGCCGTGGCCTGTCCCGTGTGTACCCTGTATTTGCGCGAGGGCATCAGTCTGCAGAAGCATCTGGATACTCACCCCAAGGAACAGGTTATAGAGGCCCTCATCAAAGCCAGCGCCTCCTCGTTACAGACCCaacagcaccagcaccagcagcATCAACAAGCTCTACCAGCGTCAGCAGCAACGTCATTACCATTATCGCCGCAGCCGCAGGCTGCGCTTCAGACCCCTACCTCCATCCAGGCGCCCCAAGCGTCCACCCAAGTATCGCAGAACGCGCACATTTCCACTCACTCTCCGTATCCCGTAGGACCCATCTTCGAATGTCCGCCCATAAGCACCGTGATGCCGCCGCAGTTCACCTCGTTCAGCTATCAGCAATTCGTGAACAATGGGACCATGATGATACCGCAGTACGCGATGGCGCCGCAAGCCAATCAGATGATGCAGATGCTGTATCCATACGGTATGTACCAACAGCAAATACCCACCGTCCAAATGATCTCACCAGTTGCAGCTATTCCCggggcgacgacgacgacgagggtCCGACCGGTGGTCACCGTGGCCGGGGAGAGCAACGTCAGAACCCTGACGGTTCCTGTAAATAGTCCCGAGCCGAAGCAGATCCTACCGGAGATACTGCCGGATACGGAGCCTGAGTCCGGGCAGGTTATACCGGACGTGACCCTCTCGGCCTCGCCTGTGCTGCAAAATGAGGATACATCCGTCAGAGCGAGGGAGGAGAGCGACGGCGGCGCGCTGCCGATCGATCACCGAGGACAGCAGACGCAGGGTCCTGCGTCTCCCGGTGAAAGCGCGGCGCAGCACGAATACAATGCTATTCCTAGGTCTATTACAATTGCCTGCGCTATAGATGACACGGATGACAAGGTGGAGAGTGTATTGCCAGACATGGTGGACGAGGAGGAGCCATCGAACAACATTTTGACCACGGACTTGCAGTGTAAATCTGTGACGTACGAGCAATCGGAAACGCAACAGTTCGCGCGACAAGTCGTCGACGAGGGATACGTGAGTGTATCCGGCAGAAAAATACCCAATGAGACGGTCGATATCGATTCCGTAGCTTCCGAGCGCGAATCGGAAGTGACGAGTGACGAAGGACCCGCGAGTCCCGGCAGCAACGTCAACAGCAACGTCGGATCGCCGCGGGATCTGATAGCGATAGACGCGTTAAAGGACTCTGTCCAACCTGAGCTTAACTCGGTGGAAAAATTGGAGAATTTGATAACCATAATGGAAACGGAGCTCAATAACGCTTCGCTTCAGAAGGAAAGTGACACGCCGAACGATCAGGAGAGACTGACGGACACGAAGGAGAAAACCGCCGCGGTGGATAGGGAGGAGACTGTGATTCACGACACGGTGGTCACGATACCGGGCTCCCACGAGAAGGATCACGTATTGCCCGACGTACGGGAGGAGAGCAAGTGGGACTCGAGCAATTACATACCCAACGAACTGAGAACGCTAGAGAAAACTTGTGACTCGTCGTACGGAGTAAACTGCGTGAAAATAAATGACGCGCTGGAAGGACTGGAGAGAACTTTTCGTTCGGATAATTATAAGTATAGTTTTTCAGCGCCCGCGTCCCCAGTCGCGAGGAAGAAGAGCCGCAGAGTCGTGCGCCGCTACAGCTCGCGATCGGAACATGGGTCGTGCGAAAATCTCAGCGCGTATCGCTACCGTGCCGCTTTCGACGACGCCGTAACGATgcacgaagacgacgacgacgaagacgacgacgacgacgacgatgacgaggacgacgaggaCGTGGACGATCTCGAGAAGATCGAGGAGGATAACTTCGACGAGGCGGACATGGAGATCGACGAGATTCCCAGTCCGCACACGCCTTTCGCGGACTGCGGCGTCAGATCGCACACGCCGCTGTCCACGATCAGCGGCATTTCCGTGTTAAGAGTTAGGAAAGATCTAAGCAAGCCGTGCTCACCCACGTCCATGCATTCGTTTCATCACGTGGACAGCGATAGCGTGACTCACGACGAGGACAGCAACGGCGTGGGTAACACCGCGGAGAAGGATCCAATTGACTGTTCGCAGGTGGACGAGGAGAAAATCAAGACTGATCATCGGCATCGGGAGACGCAGGCGGTGGCGGTGTGCGGAAGTATCGCCAAGGTTCAGGAGTCGAGCAGCAGTTACGCGTACCATCAATCAGTGATAACCGAGCACATCAGCTCGTTTCCCGTGATACACTCGCAGTCGTCCGTCTTGATGCACGAGTCGTATTCCATCACGACCAGCACCAAGACGCAAAACCTCCTGAATCTCTCCGAATCGATAAATCCCACAACCAGCACCGAATCGAGAAGCTTTCACTCCGCCAAGTCGTTGACGCCGAAGCAATCGATGGAACTGCTCAACATAAATGAAGATGCTCATGCCGGGCCAATGAATGTCTTTGAATTCGACGGACTGCAAATATTAGTTCCTAGTTCGTTTATAAGTGACTCGTCCCAGAAAGCGGTGAGTGCGACCAGCCAGCAATCTATGGCGAGTAGCGAGGGTGCAATAGGTATCGACGAGGAGGTGAAGAGTATTAATATGCGCGCCGACGAGACCATGCCGCCTAGGGGTGAATTGTCGGAGCAAGAGAGTAATGGATGCACGGAGCAATCCGCATGGCAGTTGTACATGGGTCAAGAATCGTCACGTATGTCCACCTCTTACGATTTGTTGGCTCGAGAAAGCTGGGAAGAATCGGAGGGATCCGACAACGAGATCAGCGGGCCGTTGTTGGACAGCAGATCGTTGGCCACGCACTTTACTTCGAGTCTGTTTCTGGATCGGGACCGAAAGACACCGACTAAACGAACATTCAAGTGTTCCCACTGCAGCGAAGTGTTTGATTGCCCGAAAGAACGTAGAGTTCACAGCACAACGGTACACAAGGATGCGATGCCCAGTAGCAGTAGAGACCAGCTGGATCAGCCGGAGGTGAAGGACATCAAGTTGCTGGACAGTCGCATGAACATGTTCGACGACATATTCATGCCGAGTATACACATGCAGCAGCACATGTATCATCATCAGCAGCCGCTCCTGCACCAACTACAGCCACCGTCGCAGCCTGGATCGGACGGCCTGACGAAGGCCGAGGCCGACCAGAAGATCGGCGAGAATCTGGTGATACCGTCGAACATCGAGGTGATCTGCACAATATGCAATCAGCGATTCAACAGCGAGAAGTCCCTGCAGGCGCATCACCGGCGCGTGCACATCGCCGACGTGAACAAACGCATACGCGAGACCGCCAAGTGTCAGATATGCAACGAGGAATTCCCGTCGGTGTTCCTGTACAACGCTCACCTGAAGATACACCCGTTAGAGTGCGGACAGTGCGGCAAGTATTTTTATCGCAAGCAAAACTTCAAGCTCCACATGAAACGTCACTTGGGGATCAAGCCGTTCCCGTGTACCGTGTGCGACAAGGCGTTCCTCACCAAGCAGAAGCTGGAGGAGCACACCAACGGCCACACCGGCAACGCGCCCGTCAGGTGTAGTCTGTGTAACGAGACCTTCCGCAGATACTCGAATCTGACCCAGCACAAAAACAGGCATCACCTCAACATCAAGAAGAAGCTCAAGGACTACATATGCCACTGCGGCGAGGTGTTCCACACGAAGAAGAAGCTCGCCTGGCACAAGGAGACGCACGACGAGAAGCCTAAGGCGTGCACGTACTGCAACGAGCGATTTATCCACATGGCCAGTCTGACGCGTCACATGCGTCGCGCCCACAATCGCCGATTCGTTCCCGATGCTCAGCGCGAGAGCGAGAACGTCGAGTGTCCGATCTGCAAGTGCATCTACCTGCGATCGTCCCTGGCGGTGCACATGCGCGTGCACAACGGTGAGCGGCCGTACGAGTGTCAGGTCTGCTCCAAGGCGTTCAGCACCAAGTGGAACCTGCAGCTGCACAAGTGGACGCACGCGGCGCGCAGCACCAAGCCGTTCAAGTGCAACCAGTGCAGCGCGGCGTTCTACCGTCACAGCGATTACACGGCCCACATGAATTCCCATCGGAACGTACGGCCGTACACGTGCAACTACTGCGGCGCGCAGTTCATCCGCAAGTACAACTGCCTGCGGCACGTGAAGGAGCACGAGGAGAACAAGGCGTACACGTGCGACGTGTGCAACAAGACCTTCCATCGCTCGTACTATCTCAAGGAGCATCTACGGGTGCATTCGGGCGCGCGTCCGTACACATGTCACATCTGCGGCAAGTCCAGCGGCACGAAGTCCAATCACAACAAGCACGTGCGAATTCATCACGCGCGCGAGCCTGTAAATACCGAAAATTGA
Protein Sequence: MELNGAGTPVGAVACPVCTLYLREGISLQKHLDTHPKEQVIEALIKASASSLQTQQHQHQQHQQALPASAATSLPLSPQPQAALQTPTSIQAPQASTQVSQNAHISTHSPYPVGPIFECPPISTVMPPQFTSFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYPYGMYQQQIPTVQMISPVAAIPGATTTTRVRPVVTVAGESNVRTLTVPVNSPEPKQILPEILPDTEPESGQVIPDVTLSASPVLQNEDTSVRAREESDGGALPIDHRGQQTQGPASPGESAAQHEYNAIPRSITIACAIDDTDDKVESVLPDMVDEEEPSNNILTTDLQCKSVTYEQSETQQFARQVVDEGYVSVSGRKIPNETVDIDSVASERESEVTSDEGPASPGSNVNSNVGSPRDLIAIDALKDSVQPELNSVEKLENLITIMETELNNASLQKESDTPNDQERLTDTKEKTAAVDREETVIHDTVVTIPGSHEKDHVLPDVREESKWDSSNYIPNELRTLEKTCDSSYGVNCVKINDALEGLERTFRSDNYKYSFSAPASPVARKKSRRVVRRYSSRSEHGSCENLSAYRYRAAFDDAVTMHEDDDDEDDDDDDDDEDDEDVDDLEKIEEDNFDEADMEIDEIPSPHTPFADCGVRSHTPLSTISGISVLRVRKDLSKPCSPTSMHSFHHVDSDSVTHDEDSNGVGNTAEKDPIDCSQVDEEKIKTDHRHRETQAVAVCGSIAKVQESSSSYAYHQSVITEHISSFPVIHSQSSVLMHESYSITTSTKTQNLLNLSESINPTTSTESRSFHSAKSLTPKQSMELLNINEDAHAGPMNVFEFDGLQILVPSSFISDSSQKAVSATSQQSMASSEGAIGIDEEVKSINMRADETMPPRGELSEQESNGCTEQSAWQLYMGQESSRMSTSYDLLARESWEESEGSDNEISGPLLDSRSLATHFTSSLFLDRDRKTPTKRTFKCSHCSEVFDCPKERRVHSTTVHKDAMPSSSRDQLDQPEVKDIKLLDSRMNMFDDIFMPSIHMQQHMYHHQQPLLHQLQPPSQPGSDGLTKAEADQKIGENLVIPSNIEVICTICNQRFNSEKSLQAHHRRVHIADVNKRIRETAKCQICNEEFPSVFLYNAHLKIHPLECGQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLEEHTNGHTGNAPVRCSLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRESENVECPICKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01523563;
90% Identity: iTF_00128452;
80% Identity: -