Basic Information

Insect: Aphaenogaster picea
Gene Symbol: ZFX
Assembly: GCA_003063865.1
Location: NJRM01000059.1:1529-6660[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.7 1.9e+02 3.3 0.1 3 23 15 35 14 35 0.94

2 15 3.3 3.7e+02 2.4 3.8 1 23 960 983 960 983 0.81

3 15 0.00013 0.015 16.2 1.9 3 23 1072 1093 1070 1093 0.96

4 15 0.0029 0.33 12.0 0.2 2 23 1106 1127 1106 1127 0.98

5 15 1.8e-05 0.0021 18.9 2.3 2 23 1130 1151 1129 1151 0.97

6 15 0.0023 0.26 12.3 0.3 1 23 1157 1179 1157 1179 0.96

7 15 4.4e-05 0.005 17.7 4.3 2 23 1186 1207 1185 1208 0.95

8 15 0.11 13 7.0 3.7 5 23 1221 1239 1220 1239 0.97

9 15 2.3e-05 0.0026 18.6 1.5 3 23 1246 1267 1245 1267 0.97

10 15 0.01 1.2 10.2 0.3 2 23 1283 1303 1282 1303 0.97

11 15 6.9e-05 0.0078 17.1 0.7 1 20 1309 1328 1309 1331 0.92

12 15 8.6e-05 0.0096 16.8 2.7 1 23 1339 1361 1339 1361 0.99

13 15 0.0024 0.27 12.2 3.2 1 23 1367 1389 1367 1389 0.97

14 15 4.3e-06 0.00049 20.9 3.9 1 23 1395 1417 1395 1417 0.99

15 15 0.0015 0.17 12.9 6.3 1 23 1423 1445 1423 1446 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.7	1.9e+02	3.3	0.1	3	23	15	35	14	35	0.94
2	15	3.3	3.7e+02	2.4	3.8	1	23	960	983	960	983	0.81
3	15	0.00013	0.015	16.2	1.9	3	23	1072	1093	1070	1093	0.96
4	15	0.0029	0.33	12.0	0.2	2	23	1106	1127	1106	1127	0.98
5	15	1.8e-05	0.0021	18.9	2.3	2	23	1130	1151	1129	1151	0.97
6	15	0.0023	0.26	12.3	0.3	1	23	1157	1179	1157	1179	0.96
7	15	4.4e-05	0.005	17.7	4.3	2	23	1186	1207	1185	1208	0.95
8	15	0.11	13	7.0	3.7	5	23	1221	1239	1220	1239	0.97
9	15	2.3e-05	0.0026	18.6	1.5	3	23	1246	1267	1245	1267	0.97
10	15	0.01	1.2	10.2	0.3	2	23	1283	1303	1282	1303	0.97
11	15	6.9e-05	0.0078	17.1	0.7	1	20	1309	1328	1309	1331	0.92
12	15	8.6e-05	0.0096	16.8	2.7	1	23	1339	1361	1339	1361	0.99
13	15	0.0024	0.27	12.2	3.2	1	23	1367	1389	1367	1389	0.97
14	15	4.3e-06	0.00049	20.9	3.9	1	23	1395	1417	1395	1417	0.99
15	15	0.0015	0.17	12.9	6.3	1	23	1423	1445	1423	1446	0.96

Sequence Information

Coding Sequence: ATGGAGCTCAACGGTGCGGGAACGCCCGTCGGGGCCGTGGCCTGTCCTGTGTGCACCCTGTATTTGCGCGAGGGCATCAGTCTGCAGAAGCATCTGGACACTCATCCCAAGGAACAGGTTATAGATGCTCTCATCAAAGCCAGCGCCTCCTCGTTACagtcgcagcagcagcagcaacagcaacaacagcagcagcagcaagctTTACCAGCATCAGCAGCAACGTCACTACCGTTATCATTGCAGCCGCAAGCTGCGCTTCAGACCCCTACCTCCATCCAGGCGCCCCAAGCGTCCACCCAAGTCTCGCAGAACACGCACATTTCTACTCACTCTCCATATCCCGTAGGACCCATCTTCGAATGTCCGCCCATAAACACCATGATGCCGCCGCAGTTCACCTCATTCAGCTATCAGCAATTCGTGAACAATGGGACCATGATGATACCGCAGTACGCGATGGCGCCACAAGCCAATCAGATGATGCAGATGCTGTACAATCCATACGGTATGTACCAACAGCAAATACCCACCGTCCAAATGATCTCACCAGTTGCAGCTATTCCTGGCGCGACGACGAGGGTGCGACCAGTGGTCACTATGGCTGGGGAGAGCAACGTCAGAACCCTGACGGTTCCTGTAAATAGTCCCGAGCCGAAGCAGATTCTGCCTGAGATTTTACCGGAGACGGAGCCCGAATCCGGCCAAGTTATACCGGATGTGAGCCTCTCAGTCTCGCCTGTACTACAAAATGAGGATACATCCGTCAGAGCAAGGGAGGAGAGCGCCAGCAGTGCGCTGCCAATTGATCATCGAGGACAACAGACACAGAGCTCTGCATCTCCTGGTGATAGCACGGTGCAGCATGAGTATAATGCTATTCCTAGATCTATTACAATTGCTTGCGCTATAGATAATACTGATGATAAAGTGGAGAGTGTATTGCCAGACATGATGGACGAGGAGCCATCAAGCAACATTTCGACGGACTTACAATGTAAATCTGTAACGTATGAGCAACCAGAAACACAACAGTTTACACAACAAGTTATCGACGAAGGATACGTAAGTGTATCCAATAGGAAAACACCCAATGGGATAGCTGAAATTGACTCCATGATTTGCGAGCGTGAATCGGAAGTGATAAGTGATGAAAGGCCCACAAGACGCAGCAGCAACGTTGCATCACCGCGGGATCTGATTGCAATAGACGCATTGAAAGATTCTGTCCAACCCGAGCTTAACTCGgtagaaaaattggaaaatttgatAACTATAATGGAGACGGAACTCAATAACGCTTCGCTTCAGGAAGAAAGTAATATACAAAACGATCAGGAGAGATTGGTGGACACGAAGGAGAAAACTACCGTAATAGATAGGGAGGAGAGCGTGATACACGATACAGTAGTCACGATCCCGGGCTCCCATGAAAAGGATCACATATTGCCCGACATACAGGAAGAGAACAAGTGGTGCTCGAGCAATTACGTAGCTAACGAACTGAGAACGCTAGAAAAAACTTGTAGTTTGTCATACAAAGTAGACTGCGCGAAAATAAATGAAGCACTGGAAAGATTGGAGAGACTGGAAAGAACTTTTCATTCGACTAATTATAAGTATAGTTTTTCAGCGCCCGCGTCCCCGGTCCCGAGAAGGAAGAACCGCAGGATCGTGCGTCGTTACAGCTCGCGATCGGAGCATGGATCGTGCGAAAATCTCAGCGCGTATCGTCATCGCGTCGGTTTCGACGCGGCCATGcatgaggacgacgacgacgatgacgacgacgacgatgatgacgaggaCGTGGACGAGGATGAGAAGATCGACGAGGAGGATAATTTCGATGAGGCGGACATGGAGATCGACGAGATCCCCAGTCCGCACACACCTTTCGCGGATTGCGGCGTCAGATCGCACACGCCGTTGTCCACGATCAGCGGCATTTCTGTATTAAGAGTTAGAAAGGATCTCAGCAAACCATGTTCACCCACGTCCATGCATTCGTTTCATCACGTGGACAGCGATAGCGTAACTCATGACGAGGACAGTAACGGCGTAGGTAACACCGCAGAGAAGGATCCAATCGACTGTTCTCAGGTGGAGGAGGAGAAAATCAAGACTGATCATCAGCAGCAGGAGACGCAGGTGGCGGTGTGCGGAAGTGTCGCAAAGGTTCAGGAATCGAGCAGTAGCTACGCGTACCATCAATCAGTGATAACCGAACACATTAGTTCATTCCCCGTGATACACTCGCAGTCGTCCGTCTTGATGCACGAGTCGTATTCCATTACGACGAGCACCAAGACGCAGAACCTCTTGAATCTCTCCGAGTCAATAAATCCCACAACCAGCACCGAATCCAGAAGCTTTCACTCTGCCAAGTCGTTGATGCCGAAGCAATCGATGGAACTGCTCAACATAAATGAAGATGCTCACGCCGGGCCAATGAATGTCTTTGAATTCGACGGACTGCAAATATTAGTTCCTAGTACGTTTATAAGTGACTCGTCCCAGAAAGCGGTGAGTGCGACCAGCCAGCAATCTATGGCGAGTAGCGAGGGTGCAATAGGTATCGACGAGGAGGTGAAGAGTATTAATATGCGTGCCGATGAGACCATGCCGCCTAGGGGCGAATTGTCGGAACAAGAGAGTAATGGATGCACGGAGCAGTCTGCATGGCAGTTGTACATGGGTCAAGAATCTTCGCGCATGTCCACCTCTTACGATCTGTTGGCTCGAGAAAGCTGGGAAGAATCAGAAGGATCTGACAACGAGATCAGCGGACCGTTGTTGGATAGTAGATCGTTGGCCACGCACTTTACTTCGAGTCTGTTTCTGGATCGGGACCGAAAGACACCGACTAAACGAACATTCAAGTGTTCCCACTGTAGCGAAGTGTTTGATTGTCCAAAGGAGCGTAGAGTTCATAGCACAACGGTGCACAAGGATGCGATGCCCAGTAGCAGTAGAGATCAGTTGGATCAGCCAGAAGTAAAGGACATCAAGTTGCTGGACAGTCGCATGAATATGTTTGACGATATATTCATGCCGAGTATACACATGCAACAACACATGTACCATCATCAGCAGCCGCTCTTGCACCAGTTGCAGCCACCGTCGCAGCCTGGATCGGATGGCCTGACAAAGGCCGAGGCCGACCAGAAAATCGGCGAGAATCTAGTAATACCGTCGAACATCGAGGTGATCTGTACCATATGCAATCAGCGATTCAATAGCGAGAAATCCCTACAGGCGCATCACCGGCGCATGCATATCGCCGACGTGAACAAACGCATACGCGAGACCGCAAAGTGTCAGATATGCAATGAGGAATTTCCATCGGTATTCCTATTTAATGCTCATCTGAAGATACACCCGTTAGAGTGCGGACAGTGCGGCAAGTATTTCTACCGGAAGCAGAACTTCAAGCTCCACATGAAACGTCACCTGGGCATCAAGCCGTTCCCGTGTACCGTGTGCGACAAGGCATTCCTTACCAAGCAGAAACTGGAGGAGCACACCAACGGCCACACCGGCAACGCGCCCGTCAGGTGTAGTTTGTGCAATGAGACCTTCCGTAGATATTCGAATCTGACACAGCACAAAAACAGACATCATCTCAACATCAAGAAGAAGCTCAAGGATTACATATGCCACTGTGGCGAGGTGTTTCACACGAAGAAGAAGCTCGCCTGGCACAAAGAGACTCACGACGAGAAGCCCAAGGCGTGCACGTACTGCAACGAGCGATTTATCCACATGGCCAGCCTGACGCGTCACATGCGTCGCGCCCACAATCGCCGCTTCGTTCCCGACGCTCAGCGCGAGAGCGAGAATGTCGAGTGCCCGATCTGCAAGTGTATCTACCTGCGATCGTCGCTAGCGGTGCATATGCGCGTGCACAACGGCGAGCGGCCGTACGAGTGTCAGGTCTGCTCCAAGGCGTTCAGCACCAAATGGAACCTGCAGCTGCACAAGTGGACACACGCGGCGCGCAGTACCAAGCCCTTCAAATGTAATCAGTGCAGCGCGGCGTTCTACCGTCACAGCGATTACACGGCGCACATGAATTCCCATCGGAACGTGCGGCCGTACACGTGCAACTactgcggcgcgcagttcatcCGCAAGTACAACTGCCTGCGGCACGTGAAGGAGCACGAAGAGAACAAGGCATACACGTGCGACGTGTGCAATAAGACCTTCCACCGCTCGTACTATCTCAAGGAGCACCTGCGGGTGCACTCGGGCGCGCGGCCGTACACGTGTCACATCTGCGGCAAGTCCAGCGGCACCAAATCCAATCACAACAAGCACGTGCGAATCCATCACGCGCGCGAGCCTGTAAATACCGAGAATTGA
Protein Sequence: MELNGAGTPVGAVACPVCTLYLREGISLQKHLDTHPKEQVIDALIKASASSLQSQQQQQQQQQQQQQALPASAATSLPLSLQPQAALQTPTSIQAPQASTQVSQNTHISTHSPYPVGPIFECPPINTMMPPQFTSFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQIPTVQMISPVAAIPGATTRVRPVVTMAGESNVRTLTVPVNSPEPKQILPEILPETEPESGQVIPDVSLSVSPVLQNEDTSVRAREESASSALPIDHRGQQTQSSASPGDSTVQHEYNAIPRSITIACAIDNTDDKVESVLPDMMDEEPSSNISTDLQCKSVTYEQPETQQFTQQVIDEGYVSVSNRKTPNGIAEIDSMICERESEVISDERPTRRSSNVASPRDLIAIDALKDSVQPELNSVEKLENLITIMETELNNASLQEESNIQNDQERLVDTKEKTTVIDREESVIHDTVVTIPGSHEKDHILPDIQEENKWCSSNYVANELRTLEKTCSLSYKVDCAKINEALERLERLERTFHSTNYKYSFSAPASPVPRRKNRRIVRRYSSRSEHGSCENLSAYRHRVGFDAAMHEDDDDDDDDDDDDEDVDEDEKIDEEDNFDEADMEIDEIPSPHTPFADCGVRSHTPLSTISGISVLRVRKDLSKPCSPTSMHSFHHVDSDSVTHDEDSNGVGNTAEKDPIDCSQVEEEKIKTDHQQQETQVAVCGSVAKVQESSSSYAYHQSVITEHISSFPVIHSQSSVLMHESYSITTSTKTQNLLNLSESINPTTSTESRSFHSAKSLMPKQSMELLNINEDAHAGPMNVFEFDGLQILVPSTFISDSSQKAVSATSQQSMASSEGAIGIDEEVKSINMRADETMPPRGELSEQESNGCTEQSAWQLYMGQESSRMSTSYDLLARESWEESEGSDNEISGPLLDSRSLATHFTSSLFLDRDRKTPTKRTFKCSHCSEVFDCPKERRVHSTTVHKDAMPSSSRDQLDQPEVKDIKLLDSRMNMFDDIFMPSIHMQQHMYHHQQPLLHQLQPPSQPGSDGLTKAEADQKIGENLVIPSNIEVICTICNQRFNSEKSLQAHHRRMHIADVNKRIRETAKCQICNEEFPSVFLFNAHLKIHPLECGQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLEEHTNGHTGNAPVRCSLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRESENVECPICKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01523563;
90% Identity: iTF_00128452;
80% Identity: iTF_00129958;