Basic Information

Insect: Aphaenogaster ashmeadi
Gene Symbol: ZFX
Assembly: GCA_003063805.1
Location: NJRQ01000045.1:1466-6591[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.7 1.9e+02 3.3 0.1 3 23 15 35 14 35 0.94

2 15 3.2 3.6e+02 2.4 3.8 1 23 956 979 956 979 0.81

3 15 0.00013 0.015 16.2 1.9 3 23 1068 1089 1066 1089 0.96

4 15 0.0029 0.33 12.0 0.2 2 23 1102 1123 1102 1123 0.98

5 15 1.8e-05 0.002 18.9 2.3 2 23 1126 1147 1125 1147 0.97

6 15 0.0023 0.25 12.3 0.3 1 23 1153 1175 1153 1175 0.96

7 15 4.4e-05 0.005 17.7 4.3 2 23 1182 1203 1181 1204 0.95

8 15 0.11 13 7.0 3.7 5 23 1217 1235 1216 1235 0.97

9 15 2.3e-05 0.0025 18.6 1.5 3 23 1242 1263 1241 1263 0.97

10 15 0.01 1.2 10.2 0.3 2 23 1279 1299 1278 1299 0.97

11 15 6.8e-05 0.0077 17.1 0.7 1 20 1305 1324 1305 1327 0.92

12 15 8.5e-05 0.0096 16.8 2.7 1 23 1335 1357 1335 1357 0.99

13 15 0.0024 0.27 12.2 3.2 1 23 1363 1385 1363 1385 0.97

14 15 4.3e-06 0.00049 20.9 3.9 1 23 1391 1413 1391 1413 0.99

15 15 0.0015 0.17 12.9 6.3 1 23 1419 1441 1419 1442 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.7	1.9e+02	3.3	0.1	3	23	15	35	14	35	0.94
2	15	3.2	3.6e+02	2.4	3.8	1	23	956	979	956	979	0.81
3	15	0.00013	0.015	16.2	1.9	3	23	1068	1089	1066	1089	0.96
4	15	0.0029	0.33	12.0	0.2	2	23	1102	1123	1102	1123	0.98
5	15	1.8e-05	0.002	18.9	2.3	2	23	1126	1147	1125	1147	0.97
6	15	0.0023	0.25	12.3	0.3	1	23	1153	1175	1153	1175	0.96
7	15	4.4e-05	0.005	17.7	4.3	2	23	1182	1203	1181	1204	0.95
8	15	0.11	13	7.0	3.7	5	23	1217	1235	1216	1235	0.97
9	15	2.3e-05	0.0025	18.6	1.5	3	23	1242	1263	1241	1263	0.97
10	15	0.01	1.2	10.2	0.3	2	23	1279	1299	1278	1299	0.97
11	15	6.8e-05	0.0077	17.1	0.7	1	20	1305	1324	1305	1327	0.92
12	15	8.5e-05	0.0096	16.8	2.7	1	23	1335	1357	1335	1357	0.99
13	15	0.0024	0.27	12.2	3.2	1	23	1363	1385	1363	1385	0.97
14	15	4.3e-06	0.00049	20.9	3.9	1	23	1391	1413	1391	1413	0.99
15	15	0.0015	0.17	12.9	6.3	1	23	1419	1441	1419	1442	0.96

Sequence Information

Coding Sequence: ATGGAGCTCAACGGTGCGGGAACGCCCGTCGGGGCCGTGGCCTGTCCTGTGTGCACCCTGTATTTGCGCGAGGGCATCAGTCTGCAGAAGCATCTGGACACTCATCCCAAGGAACAGGTTATAGATGCTCTCATCAAAGCCAGCGCCTCCTCGTTACAGtcgcagcaacaacagcagcagcagcaagcTTTACCAGCATCAGCAGCAACGTCACTACCGTTATCATTGCAGCCGCAAGCTGCGCTTCAGACCCCTACCTCCATCCAGGCGCCCCAAGCGTCCACCCAAGTCTCGCAAAACGCGCACATTTCTACTCATTCTCCATATCCCGTAGGACCCATCTTCGAATGTCCACCCATAAACACCATGATGCCGCCGCAGTTCACCTCATTCAGCTATCAGCAATTCGTGAACAATGGGACCATGATGATACCGCAGTACGCGATGGCGCCACAAGCCAATCAGATGATGCAGATGCTATACAATCCATACGGTATGTACCAACAGCAAATACCCACCGTCCAAATGATCTCACCAGTTGCAGCTATTCCTGGCGCGACGACGAGGGTGCGACCAGTGGTCACTATGGCTGGGGAGAGCAACGTCAGAACCCTGACGGTTCCTGTAAATAGTCCCGAGCCGAAGCAGATTCTGCCTGAGATTTTACCGGAGACGGAGCCCGAATCCGACCAAGTTATACCGGATGTGAGCCTCTCAGTCTCGCCTGTACTACAAAATGAGGATACATCCGTCAGAGCAAGGGAGGAGAGCGCCAGCAGTGCGCTGCCAATTGATCATCGAGGACAACAGACACAGAGCTCTGCATCTCCTGGTGATAGCACGGTGCAGCATGAGTATAATGCTATTCCTAGATCTATTACAATTGCTTGCGCTATAGATAATACCGATGATAAAGTGGAGAGTGTATTGCCAGACATGGTGGACGAGGAGCCATCAAGCAACATTTCGACGGACTTACAGTGTAAATCTGTAACGTATGAGCAACCAGAAACACAACAGTTTACACAACAAGTTATCGACGAAGGATACGTAAGTGTATCCAATAGGAAAACACCCAATGGGATAGCTGAAATTGACTCCATGATTTGCGAGCGTGAATCGGAAGTGATAAGTGATGAAAGGCCCACAAGTCGCAGCAGCAACGTTGCATCACCGCGGGATCTGATTGCAATAGACGCATTGAAAGACTCTGTCCAACCCGAGCTTAACTCGGtagaaaaattggaaaatttgatAACTATAATGGAGACGGAACTCAATAACGCTTCGCTTCAGAAAGAAAGTAATACACAAAACGATCAGGAGAGATTGGTGGACACGAAGGAGAAAACTACCGTAATAGATAGGGAGGAGAGCGTGATACACGATACAGTAGTCACGATCCCGGGCTCCCATGAAAAGGATCACATATTGCCCGACATACAGGAAGAGAACAAGTGGTGCCCGAGCAATTACGTAGCTAACGAACTAAGAACGCTAGAAAAAACTTGTAGTTTGTCATACAAAGTAGACTGCGCGAAAATAAATGAAGCACTGGAAAGATTGGAGAGACTGGAAAGAACTTTTCATTCGACTAATTATAAGTATAGTTTTTCAGCGCCCGCGTCCCCGGTCCCGAGAAGGAAGAACCGTAGGATCGTGCGTCGTTACAGCTCGCGATCGGAGCATGGATCGTGCGAAAATCTCAGCACGTATCGTCATCGCGTCGGTTTCGACGCGGCCATGCatgaggacgacgacgacgacgatgacgacgacgacgatgatgacgagGACGTGGACGAGGATGAGAAGATCGACGAGGAGGATAATTTCGATGAGGCGGACATGGAGATCGACGAGATCCCCAGTCCGCACACACCTTTCGCGGATTGCGGCGTCAGATCGCACACGCCGTTGTCCACGATCAGCGGCATTTCTGTATTAAGAGTTAGAAAGGATCTCAGCAAACCATGTTCACCCACGTCCATGCATTCGTTTCATCACGTGGACAGCGATAGCGTAACTCATGACGAGGACAGTAACGGCGTAGGTAACACCGCAGAGAAGGATCCAATCGACTGTTCTCaggtggaggaggagaaaATCAAGACTGATCATCAGCAGCAGGAGACGCAGGTGGCGGTGTGCGGAAGTGTCGCAAAGGTTCAGGAATCGAGCAGTAGCTACGCGTACCATCAATCAGTGATAACCGAACACATTAGTTCATTCCCCGTGATACACTCGCAGTCGTCCGTCTTGATGCACGAGTCGTATTCCATTACGACGAGCACCAAGACGCAGAACCTCTTGAATCTCTCCGAGTCAATAAATCCCACAACCAGCACCGAATCCAGAAGCTTTCACTCTGCCAAGTCGTTGATGCCGAAGCAATCGATGGAACTGCTCAACATAAATGAAGATGCTCACGCCGGGCCAATGAATGTCTTTGAATTCGACGGACTGCAAATATTAGTTCCTAGTACGTTTATAAGTGACTCGTCCCAGAAAGCGGTGAGTGCGACCAGCCAGCAATCTATGGCGAGTAGCGAGGGTGCAATAGGTATCGACGAGGAGGTGAAGAGTATTAATATGCGTGCCGATGAGACCATGCCGCCTAGGGGCGAATTGTCGGAACAAGAGAGTAATGGATGCACGGAGCAGTCTGCATGGCAGTTGTACATGGGTCAAGAATCTTCGCGCATGTCCACCTCTTACGATCTGTTGGCTCGAGAAAGCTGGGAAGAATCAGAAGGATCTGACAACGAGATCAGCGGACCGTTGTTGGATAGTAGATCGTTGGCCACGCACTTTACTTCGAGTCTGTTTCTGGATCGGGACCGAAAGACACCGACTAAACGAACATTCAAGTGTTCCCACTGTAGCGAAGTGTTTGATTGTCCAAAGGAGCGTAGAGTTCATAGCACAACGGTGCACAAGGATGCGATGCCCAGTAGCAGTAGAGATCAGTTGGATCAGCCAGAAGTAAAGGACATCAAGTTGCTGGACAGTCGCATGAATATGTTTGACGATATATTCATGCCGAGTATACACATGCAACAACACATGTACCATCATCAGCAGCCGCTCTTGCACCAGCTGCAGCCACCGTCGCAGCCTGGATCGGATGGTCTGACAAAGGCCGAGGCCGACCAGAAAATCGGCGAGAATCTAGTAATACCGTCGAACATCGAGGTGATCTGTACCATATGCAATCAGCGATTCAATAGCGAGAAATCCCTACAGGCGCATCACCGGCGCATGCATATCGCCGACGTGAACAAACGCATACGCGAGACCGCAAAGTGTCAGATATGCAATGAGGAATTTCCATCGGTATTCCTATTTAATGCTCATCTGAAGATACACCCGTTAGAGTGCGGACAGTGCGGCAAGTATTTCTACCGGAAGCAGAACTTCAAGCTCCACATGAAACGTCACCTGGGCATCAAGCCGTTCCCGTGTACCGTGTGCGACAAGGCATTCCTTACCAAGCAGAAACTGGAGGAGCACACCAACGGCCACACCGGCAACGCGCCCGTCAGGTGTAGTTTGTGCAATGAGACCTTCCGTAGATATTCGAATCTGACACAGCACAAAAACAGACATCATCTCAACATCAAGAAGAAGCTCAAGGATTACATATGCCACTGTGGCGAGGTGTTTCACACGAAGAAGAAACTCGCCTGGCACAAAGAGACTCACGACGAGAAGCCCAAGGCGTGCACGTACTGCAACGAGCGATTTATCCACATGGCCAGCCTGACGCGTCACATGCGTCGCGCCCACAATCGCCGCTTCGTTCCCGACGCTCAGCGCGAGAGCGAGAATGTCGAGTGCCCGATCTGCAAGTGTATCTACTTGCGATCGTCGCTAGCGGTGCATATGCGCGTGCACAACGGCGAGCGGCCGTACGAGTGTCAGGTCTGCTCCAAGGCGTTCAGCACCAAGTGGAACCTGCAGCTGCACAAGTGGACACACGCGGCGCGCAGTACCAAGCCCTTCAAATGTAATCAGTGCAGCGCGGCGTTCTACCGTCACAGCGATTACACGGCGCACATGAATTCCCATCGGAACGTGCGGCCGTACACGTGCAACTactgcggcgcgcagttcatCCGCAAGTACAATTGCCTGCGGCACGTGAAGGAGCACGAAGAGAACAAGGCATACACGTGCGACGTGTGCAATAAGACCTTCCACCGCTCGTACTATCTCAAGGAGCACCTGCGGGTGCACTCGGGCGCGCGGCCGTACACGTGTCACATCTGCGGGAAGTCCAGCGGCACCAAATCCAATCACAACAAGCACGTGCGAATCCATCACGCGCGCGAGCCTGTAAATACCGAGAATTGA
Protein Sequence: MELNGAGTPVGAVACPVCTLYLREGISLQKHLDTHPKEQVIDALIKASASSLQSQQQQQQQQALPASAATSLPLSLQPQAALQTPTSIQAPQASTQVSQNAHISTHSPYPVGPIFECPPINTMMPPQFTSFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQIPTVQMISPVAAIPGATTRVRPVVTMAGESNVRTLTVPVNSPEPKQILPEILPETEPESDQVIPDVSLSVSPVLQNEDTSVRAREESASSALPIDHRGQQTQSSASPGDSTVQHEYNAIPRSITIACAIDNTDDKVESVLPDMVDEEPSSNISTDLQCKSVTYEQPETQQFTQQVIDEGYVSVSNRKTPNGIAEIDSMICERESEVISDERPTSRSSNVASPRDLIAIDALKDSVQPELNSVEKLENLITIMETELNNASLQKESNTQNDQERLVDTKEKTTVIDREESVIHDTVVTIPGSHEKDHILPDIQEENKWCPSNYVANELRTLEKTCSLSYKVDCAKINEALERLERLERTFHSTNYKYSFSAPASPVPRRKNRRIVRRYSSRSEHGSCENLSTYRHRVGFDAAMHEDDDDDDDDDDDDDEDVDEDEKIDEEDNFDEADMEIDEIPSPHTPFADCGVRSHTPLSTISGISVLRVRKDLSKPCSPTSMHSFHHVDSDSVTHDEDSNGVGNTAEKDPIDCSQVEEEKIKTDHQQQETQVAVCGSVAKVQESSSSYAYHQSVITEHISSFPVIHSQSSVLMHESYSITTSTKTQNLLNLSESINPTTSTESRSFHSAKSLMPKQSMELLNINEDAHAGPMNVFEFDGLQILVPSTFISDSSQKAVSATSQQSMASSEGAIGIDEEVKSINMRADETMPPRGELSEQESNGCTEQSAWQLYMGQESSRMSTSYDLLARESWEESEGSDNEISGPLLDSRSLATHFTSSLFLDRDRKTPTKRTFKCSHCSEVFDCPKERRVHSTTVHKDAMPSSSRDQLDQPEVKDIKLLDSRMNMFDDIFMPSIHMQQHMYHHQQPLLHQLQPPSQPGSDGLTKAEADQKIGENLVIPSNIEVICTICNQRFNSEKSLQAHHRRMHIADVNKRIRETAKCQICNEEFPSVFLFNAHLKIHPLECGQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLEEHTNGHTGNAPVRCSLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRESENVECPICKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01523563;
90% Identity: iTF_00128452;
80% Identity: -