Nasi016215.1
Basic Information
- Insect
- Neoceratitis asiatica
- Gene Symbol
- Mbd2
- Assembly
- GCA_030068015.2
- Location
- CM061529.1:27580237-27582129[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 1.5e-27 3.6e-24 84.4 0.0 1 73 7 74 7 78 0.95 2 2 0.00089 2.1 8.3 0.0 29 72 214 268 197 273 0.79
Sequence Information
- Coding Sequence
- ATGAATTCCAGTATAAGCATAGAACGAAAGCGCGTAGATTGTAATTCACTACCAAAAGGATGGCAGCGGGAAGAGGTGCTTCGAAAGTCTGGTATATCAGCTGGTAAAGTCGATGTCTTCTATTACAGTCCAACcggcaaaaaaattgaaagtaaacCACAATTAGCACGATATCTAGGCGATGCTATAGATATTGGTGCATTTGATTTTCACAGCGGCAAATTCGTGCGCCATATGCCACCACCATCAATTTCTTTATTCCGCTGCAGTAATGTTAGCAGCAGTAATATCGCTGACAATGATAATACGTCAatgccgccaccaccaccacaatgTAGCGGTGGTAACACATTATCCCTATCCGTATGTTCCTCATCCATTTCTTCACAATCCCCTAATACAAATGCTAGTATACTACAATCACTTACGTCAACAACCACATCTAATACTTTGAAGCGCAAATACAAGGCGCAATCCCAATCCCAATCTCAAGTTCAGAATCAAAATCAGTCACAGACCCATCAGTCACAGGGCATGTATACGAATGTCAGTAGTAACGCTTGTACCCCACCGAGCCCATATGGTGCTGCAACGACGTCGACTGCGAGTTCACGTCAGCAATTAGAACTCAGTCGCGTGCCACGCACAGACGCGTCTCTCGTACCACCCATACGTCAAACTGCTTCGATTTTTAAACAACCAGTTACTGTAATGCGTAATCATGAGCATACAAAAGTGCGTAACGACAATAGCAATAAGGCAAGTGGTCAAGAGAAGCCAAAGCAAATGTTTTGGGAAAAACGATTGGAGGGCCTACGTGCTTGCCATCAGACTGGTGAGGAATTTGATGATATTGTGTTGCCCAAAAGCATACGAACCATTGGTCCCAATGTTAACGAGCAGACTGTATTGCAATCATTGGCCACTTCTCTGCATGTACTTAATGTGCCTGTAATGGGTCAAGCTTCAACAAAGACTGAGATGAATAAAAATGCCACAGCATTTTTGAATCCTGAACAACCGCTTATGCAAGCTGTGCTGATATCCGATGAGGATATACGGCGACAAGAGGATCGAGTTAGCCTAGCTAGAAAAAAGCTGCAAGATGCGATCAAAGCCTAA
- Protein Sequence
- MNSSISIERKRVDCNSLPKGWQREEVLRKSGISAGKVDVFYYSPTGKKIESKPQLARYLGDAIDIGAFDFHSGKFVRHMPPPSISLFRCSNVSSSNIADNDNTSMPPPPPQCSGGNTLSLSVCSSSISSQSPNTNASILQSLTSTTTSNTLKRKYKAQSQSQSQVQNQNQSQTHQSQGMYTNVSSNACTPPSPYGAATTSTASSRQQLELSRVPRTDASLVPPIRQTASIFKQPVTVMRNHEHTKVRNDNSNKASGQEKPKQMFWEKRLEGLRACHQTGEEFDDIVLPKSIRTIGPNVNEQTVLQSLATSLHVLNVPVMGQASTKTEMNKNATAFLNPEQPLMQAVLISDEDIRRQEDRVSLARKKLQDAIKA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00192813; iTF_01357949; iTF_00081224; iTF_00091242; iTF_00082129; iTF_00082941; iTF_00190670; iTF_00192087; iTF_00193561; iTF_00191359; iTF_00189952; iTF_01189424; iTF_00992594; iTF_01505401; iTF_01563774; iTF_01562893;
- 90% Identity
- -
- 80% Identity
- -