Basic Information

Gene Symbol
-
Assembly
GCA_037043435.1
Location
JBAMBK010002402.1:1031257-1035235[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.00048 0.035 14.8 0.1 1 23 156 179 156 179 0.96
2 14 0.0017 0.12 13.1 2.9 2 23 228 250 224 250 0.89
3 14 0.21 15 6.5 1.2 1 23 354 377 354 377 0.92
4 14 0.12 8.8 7.3 3.8 2 23 426 447 425 448 0.95
5 14 0.0038 0.28 12.0 0.5 1 23 514 537 514 537 0.88
6 14 2.3 1.7e+02 3.2 0.1 2 14 556 568 555 580 0.85
7 14 0.00081 0.059 14.1 3.3 2 23 588 610 588 610 0.96
8 14 0.0027 0.2 12.4 0.1 1 23 718 741 718 741 0.95
9 14 0.00013 0.0092 16.6 0.2 1 23 805 828 805 828 0.92
10 14 0.0014 0.099 13.4 2.2 2 23 878 900 877 900 0.97
11 14 0.0022 0.16 12.8 2.0 1 23 989 1012 989 1012 0.92
12 14 0.061 4.5 8.2 1.5 1 21 1064 1084 1064 1085 0.95
13 14 4.7 3.4e+02 2.3 0.1 3 23 1130 1153 1130 1153 0.74
14 14 2.7 2e+02 3.0 0.5 1 10 1171 1180 1171 1195 0.64

Sequence Information

Coding Sequence
ATGGAAGGTATGGACTTGTGGACGTCCATGTTTTCGACTGACTTTGAGGAGGGGGACGGCGAGGGAGATAATTATAATCATGGCAACAACACGCACGCAGACGAGTTTATGGgcgaagaggaggaggagggtgATATAGACGAGattcatgatgatgatgacaatgaaGGGGAACGACGCGGGAAACAAAAGGGACATGAGCCTGATGACGATGccatatttgattttgaacTGGAACCTATTGTTAGCATTGCTGAGCCAGGGTCAGCGCGAAGAGGAACTGTCGCATTGGCGCCACCAATTCCAACCGGGCCACCTGTGAGGGCTTCGCACCGTCAATCGCTGCCAGCTTCATTTGGGCCACGAGGATCTGGTGCTGGAGCAGCTCCAACGCGTCCAACGACATCCCAGATTAATGCCACCGATGAAAACGGAGTTCCAATTAATTATGAATTGGGCGTTATTTACATATGTCCCGCATGCGGCGCCGAATACCGACAGCAGGACATGTGGAAGCGTCATATGAACCAGATGCATCAGTATAATACACGCAAGGGCCTCAATTTCGTGGCCATCGATAAGCTGTATCATCGGTGCCTGGAGTGCAACAAGCGGATTGCCATGCACAGTCGGGAGAATCTGCTCAAGCATAAGTTTACCCATCTGCCATATCGGTGCACCAAGTGCTATATATGTAAACGAGAGTACAAATACAGGCAGGACCTGATGGTGCATCTGCGCATGGTGCACTGTGATGAGGTCGTGGCCATGATGCGGGAAAGCGACGGCACCGCAGGCAGGAAGACCCGTGTGCGTGAACCCCGCACCGAACCACTTTTGGGATTTTCAGCTGCCCCAGTtcatgacgatgacgatggcaTAGAAGTGAGGAATGAACATATTGAGGCGGATGTGGCTACAGGTGTTGAGGCCAGCATTAGTTTGGATGACGATCAGAGTCGCAGCTCATTAGCCAAGCGGAAGCGTGGTAATCCAGGTGCAGGTGCGGACAACGGAAATGACAGCAGTGCTGCAGATCTATGCGAGGATTACATACACTACATGTGCCCGGAGTGCAGCACCGACTGCGACACGCATGCACAGTGGAGTCAGCACATTGAGTTCGTGCACGATTATGTCAGCAGGCGAGGCCTCAACTTCCGTTGCGTGGACATGCAGATGCAGTGTCTGGAGTGCAAACAGTTTGTTATACCGAATACGATCAAGACACTGCGGGCTCACAAGTTTAGTCACTTGTCGCAGCCGGAATGGATGCGCTGCAAGTTGTGCTACAAGGGTTATACGGAGCATCAAGAACTGGTGACGCATCTGCTCAAGCATCACCATCTGGAAACTTTAATGCCCGATGCTGAGGAGACGGAGGAGCCGCTGCCAAGTGCCAATGCCGGCGATGATGGCGAGGATAATGCTGCAAATGACAACGATAATGTTTGCGATGATGACTTGTCGCATTGGGACGAAGCACCACGTCGTGGCGGACGCATCAGTAGCGATGATATGTACGAGCCCCACATTGACTATCTCTGTCCTCAGTGCGGCAGGGAATTCATCGAGAAGAAACACTGGCGCACTCATGTAGTCCAAGTGCATGGTATGAACGATCTGGGCAAGTTAAACTTCGAAGTGATCAACGACAGGCAATTGAAATGCACGGAATGCGACAAGATCATCACGAATGCATATGGCATACAGAATGCACAACAGCATCGGATCACGCATCTGCCGTACAAGGCGTACGCACGTTGCCGCAAGTGCCACAAATCGTATACGGATCGCAAGGGTTTGGTCAAGCATCTGGCAACATATCATCGAGTGGGATACGAGCCGCGTAAAGTTGCTGGAGGTGCGGGAATGAGCACGGGCAGCGGCTTGGGCTCGTCTGCCAGTGGCCAGGCATCATCCAAGTCGCAGACGCCGCGTAAACAGATTGTCACGGTGGCAAATGAAACATATGAGATTATATATTTGGATGAGGATCAATCATCGCCCggaaacaataatattaacgAGGAGAACGATTTTGGCGAACAAATGCAAGGAGATGATGATGAATACATGCCCAGTTTCAGCAGTCGTCAGTTGCCGCCTGCTGTTGCTCCCAATCCAAATCCCACAACCAATCCCAATCGCTATAAGTGCGTTGACTGCGGCTCCTTGTTTCCCACTCAGGTGGGACTCAAAACGCACATTAGCGAGGAGCATGATTTTATGGATACTCAATACAGTGCCAAAAAGTTTGATAACGCCGAACCGACTGATGAGGCACCTTCCGCTTCAGTTTCAACCCAAGAGCCTGGGGCATCGGCAAAGACATCATCAGCCTCAAGTAGCAGTAAGAAGATAGCACAAATCAATAGCTCGGGTGCATCGACCATcgaacaaaattatatattccTGTGTCCATCGTGCGGCAAGGCATACAAGACGCAGTTTGAGTGGCGCCGCCACATCAATGATGCCCACAATTTCGACAAGCGGGAATATTTGAATATGCGTCAGCTGGATAAGTATCGCTATCAATGTACTCAGTGCAAGGATATCGTGAGCAGTTCAAAGCTGAAGGGTCTGCAGGATCATCACTTTCGCCATCTGCCCTATCGACTGTATCTGAAGTGTCTCGTCTGCGGCACGTGCTACAATCACAAGCCCAACATTGCGGCTCATCTGCGCACGCGCCACAATGTCTTCGAACGTGATACGCCGTGGCGGGAGCTGCAGAACAAGCCACAGTACAACTATGTGAATACGAAGGACAAGGATAAGGATAGAGAATCTCGCGGCATATCCTCGACATCATCATCGCCGACGCCTGGAAGCAGTAGCAATTTGATGGGACGCTCGCTAAAACCACAGCCTGGCTGCCTGCCCAATCGACCGGCTGGACTGAATACTTTGGAGGAcagcatttcatttcataatGCTGTCGATATGGACTTTATCACGTACTATTGTCCCAAGTGCAACAAGAACTTTGATTCGCATGCCTTCTGGCGCAAACACATCGTGGAACAGCACAATTTCAACAGTCGCCAGGGTCTGAACTTCCGGCAGATCGACATGCATCACTACTTGTGCCTCGAGTGCTATAAGCGTGTGACTGTCACCCATACCAAGGGCGCCATCGGGCAGCTACAGTCGCACAAGTTCCGACACTTGCCCTATCGCTCCTTCAAATGCTTGACCTGCAATGGCGAATTTGTGCGCAAGCAAATGTTCTTCAAGCATTTGAATCGCGACACAAATCGCTGTGACAACAAACCACCCGGTGCCCAGGAGAACGACGAGCAGCATGATAGCATTGCTGGTGGAGATGACGCTTCTGTGCCAGCTGTAGTGGAAGTCGATCCAGCTGCCTATCGGCTGTGGTGTCCCCAATGTGGCGATAACTTTGTTACCAGCAGCAAAGCGCTTTGGCGTGAACACATAAACGCCTATCATGGCCTGGGCAAGCGAGAGATGCTCCATGTGCGAAGAGTGAGCAGTGATCTGTACCGCTGCACGGACTGTGACGAGCAGTTGCAAACGAAGCAACTTCGGGTGCTGCAGGAGCATCGTTTCAAGCATTTGCCCTATGCCGCCTATATACGCTGCCAGCTATGCGAAAATCAGCCTGATGAACTGGGTCATGGGGCTGTTGCAGCCGGTCTGCACAGTATGCAAGAGTTGCAACAACACATACGCGACAAGCATCCCGACGTAACCGAGAATGATGAACAAATGCAATCGCTACTTGATGATGAGGACAGCCAGCTGGCGAACAATGAGTCAACTGGCAATGGCCGCTAtatgccgctgccgccgcatTTGCTGGATGACGATGTCGATGACATGGATTTTGAGGGACAGTATCTGCTGGGCTAG
Protein Sequence
MEGMDLWTSMFSTDFEEGDGEGDNYNHGNNTHADEFMGEEEEEGDIDEIHDDDDNEGERRGKQKGHEPDDDAIFDFELEPIVSIAEPGSARRGTVALAPPIPTGPPVRASHRQSLPASFGPRGSGAGAAPTRPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRKGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRESDGTAGRKTRVREPRTEPLLGFSAAPVHDDDDGIEVRNEHIEADVATGVEASISLDDDQSRSSLAKRKRGNPGAGADNGNDSSAADLCEDYIHYMCPECSTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKTLRAHKFSHLSQPEWMRCKLCYKGYTEHQELVTHLLKHHHLETLMPDAEETEEPLPSANAGDDGEDNAANDNDNVCDDDLSHWDEAPRRGGRISSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLGKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKVAGGAGMSTGSGLGSSASGQASSKSQTPRKQIVTVANETYEIIYLDEDQSSPGNNNINEENDFGEQMQGDDDEYMPSFSSRQLPPAVAPNPNPTTNPNRYKCVDCGSLFPTQVGLKTHISEEHDFMDTQYSAKKFDNAEPTDEAPSASVSTQEPGASAKTSSASSSSKKIAQINSSGASTIEQNYIFLCPSCGKAYKTQFEWRRHINDAHNFDKREYLNMRQLDKYRYQCTQCKDIVSSSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNVFERDTPWRELQNKPQYNYVNTKDKDKDRESRGISSTSSSPTPGSSSNLMGRSLKPQPGCLPNRPAGLNTLEDSISFHNAVDMDFITYYCPKCNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDMHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPPGAQENDEQHDSIAGGDDASVPAVVEVDPAAYRLWCPQCGDNFVTSSKALWREHINAYHGLGKREMLHVRRVSSDLYRCTDCDEQLQTKQLRVLQEHRFKHLPYAAYIRCQLCENQPDELGHGAVAAGLHSMQELQQHIRDKHPDVTENDEQMQSLLDDEDSQLANNESTGNGRYMPLPPHLLDDDVDDMDFEGQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2