Basic Information

Insect: Drosophila funebris
Gene Symbol: -
Assembly: GCA_018901825.1
Location: JAEIFK010000678.1:21535363-21539378[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00041 0.028 14.8 0.1 1 23 167 190 167 190 0.96

2 14 0.0014 0.097 13.1 2.9 2 23 239 261 235 261 0.89

3 14 0.076 5.1 7.6 1.2 1 23 363 386 363 386 0.93

4 14 0.076 5.2 7.6 6.6 2 23 435 456 434 457 0.95

5 14 0.0032 0.22 12.0 0.5 1 23 521 544 521 544 0.88

6 14 2 1.3e+02 3.2 0.1 2 14 563 575 562 587 0.85

7 14 0.00068 0.046 14.1 3.3 2 23 595 617 595 617 0.96

8 14 0.00091 0.062 13.7 0.1 1 23 726 749 726 749 0.95

9 14 0.00011 0.0073 16.6 0.2 1 23 817 840 817 840 0.92

10 14 0.0011 0.078 13.4 2.2 2 23 890 912 889 912 0.97

11 14 0.0018 0.12 12.7 2.0 1 23 1003 1026 1003 1026 0.92

12 14 0.052 3.5 8.2 1.5 1 21 1078 1098 1078 1099 0.95

13 14 1 70 4.1 0.2 3 23 1148 1171 1148 1171 0.82

14 14 2.3 1.6e+02 3.0 0.5 1 10 1189 1198 1189 1213 0.64

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00041	0.028	14.8	0.1	1	23	167	190	167	190	0.96
2	14	0.0014	0.097	13.1	2.9	2	23	239	261	235	261	0.89
3	14	0.076	5.1	7.6	1.2	1	23	363	386	363	386	0.93
4	14	0.076	5.2	7.6	6.6	2	23	435	456	434	457	0.95
5	14	0.0032	0.22	12.0	0.5	1	23	521	544	521	544	0.88
6	14	2	1.3e+02	3.2	0.1	2	14	563	575	562	587	0.85
7	14	0.00068	0.046	14.1	3.3	2	23	595	617	595	617	0.96
8	14	0.00091	0.062	13.7	0.1	1	23	726	749	726	749	0.95
9	14	0.00011	0.0073	16.6	0.2	1	23	817	840	817	840	0.92
10	14	0.0011	0.078	13.4	2.2	2	23	890	912	889	912	0.97
11	14	0.0018	0.12	12.7	2.0	1	23	1003	1026	1003	1026	0.92
12	14	0.052	3.5	8.2	1.5	1	21	1078	1098	1078	1099	0.95
13	14	1	70	4.1	0.2	3	23	1148	1171	1148	1171	0.82
14	14	2.3	1.6e+02	3.0	0.5	1	10	1189	1198	1189	1213	0.64

Sequence Information

Coding Sequence: ATGGAAGGTATGGACTTATGGACGTCCATGTTTTCGGCAGACTTTGAGGAGGGAGACGGTGAAGGAGATAATTATAATCATGGCAATAATGCGCCTGCAGACGAGTTTGTTGCCGAAGAGGTGGAGGAGGAGGAACAGGAGGGCGATATAGATGAGATTGATGATGATGGGGAGCATGATGATAGTAGACCTCGAGGGAAGCAAAAGAGGCAAGAGCCTGATGACGATGCCATATTCGATTTCGAACTGGAGCCTATCGTAAATATCGCTGAATCAGAACCAGAGCCTGCGCGGAGAGGAGCTGTCGCATTGGCGCCACCAATGCCATCTGCACCTCCTATACGAGCTATGCAGCGTCAGTCGCTGTCGTCATCTTTTGGATCATCTTTAATGTCACGAGCTCCAGGTGCAGGTGCAGCTCCAACGCGTCCAACAACTTCACAAATCAATGCAACCGATGAAAACGGAGTTCCAATTAATTATGAATTAGGCGTTATTTACATATGCCCCGCATGCGGCGCCGAATACCGACAACAGGATATGTGGAAGCGTCACATGAACCAAATGCATCAGTATAATACCCGGAAAGGCCTCAATTTTGTTGCCATCGATAAGCTCTATCATAGGTGCCTGGAGTGCAACAAACGCATTGCCATGCACAGTAGGGAGAATCTGCTTAAGCATAAGTTTACCCATTTGCCATATCGGTGCACCAAGTGCTATATATGTAAGCGAGAGTACAAATACAGGCAGGACCTGATGGTGCATCTGCGAATGGTGCACTGTGATGAAGTAGTAGCAATGATGCGCGAAGGCGATGGTAGTGCAGGGCGGAAAACGCGTGTGCGGGAACCACGCACCGAACCACATTTAGCTCCTCAACCTGCTCCAATCCATGATGATAACGTTGGCCTAGATGTCAGAAATGAACATGTAGAAACAGACGGTGTAGCAGTCGTTGATCCTAATATCGGGTTGGATGACGATCTGAGTCGCAGCTCATTAGCCAAGCGGAAGCGTATTAATACAGTTGCAGGCAATGGGAGCGGTAGTAGTGCTGCAGATATATGTGAGGATTACATACATTATATGTGCCCGGACTGTAGCACCGAATGCGATACTCATGCCCAGTGGAGTCAGCACATTGAATTCGTGCACGATTACGTTAGTAGGCGAGGCCTCAATTTTCGATGCGTGGATATGCAGATGCAGTGCATGGAGTGCAAACAGTTTGTTATCCCGAACACGATCAAGACATTGAGAGCTCACAAATTTAGCCATTTGCCGCAACCCGATTGGATGCGTTGCAAGTTATGCTACAAGAGTTATACGGAACATCATGAACTGGTTACGCATCTGCTAAAGCATCACCATTTGGAGACATTAATGCCCGATGCTGAGGAGTCGGAGGAGCCGATGCCAAGTGCGAGTGCCGGAGATGATAGCGAGGATAACGCTGGCAATGGTCATGGCTGCGATGATGAATTAATACATTGGGACGAGGCACCACGTCGTGGCGGTCGCATAAGTAGCGATGATATGTACGAGCCTCACATTGACTATCTGTGTCCACAGTGCGGCAGGGAGTTTATCGAGAAAAAACACTGGCGGACTCATGTCGTACAAGTGCATGGAATGAACGATCTGGCCAAACTGAACTTCGAAGTAATCAATGATAGACAACTGAAATGCACTGAATGTGATAAGATCATCACGAATGCGTATGGTATACAGAATGCACAACAGCATCGGATTACGCATCTGCCGTTCAAGGCATACGCGCGCTGCCGCAAGTGCCACAAGTCGTACACGGATCGCAAGGGCTTGGTCAAGCATTTGGCCACATATCATCGTGTCGGATACGAGCCGCGTAAGGCTACTGGTGGAGCGGGAATGAGTTCGGGCAGCGGTGTGAGTATGTCTGTAAGTGGCCAGTCATCCACGACGCAGACGCAGACGCCGCGTAAACAAATTGTCACTGTGGCTAATGAAACATATGAGATTATATATTTGGATGAAGACCAATCACCACCAAGTAACAACAACATTAACGAGGAGAACGATTTTGGTGAACAAATGCAAGGAGATGATGATGAATTCACCATTGGTAGCAGTAACGCCATCAGTGGAAGCAGTCGTCAGTTGCCACCAACTGCTGCTCCTAATCCCAATCGCTACAAGTGTGTAGACTGCGGCTCCTTGTTTCCAACGCAGGCGGCACTCAAGACTCACATTAGCGAGGAGCATGATTTTATGGATACACAATACAGTGCCAAAAAGTTTGATAACGCCGAACCGACTGATGAGGCAGCATCAGCTTCAGTTTCAACTCAAGTGCCAGCGGCAGCATCGGCTGCCATAGCAAAAACATCCCCAACCACAAATAGCAATAAGAAGACACCACAAATAAACAGTTCCGGGGCTTCGACCATAGAGCAAAATTATATATTTTTGTGCCCATCGTGCGGCAAGGCATACAAGACTCAATTTGAGTGGCGTCGTCACATCAATGATGCCCACAACTTTGACAAGCGTCAATATTTGAATATGCGTCAGTTAGACAAGTATCGATATCAGTGTACTCAGTGTAAGGACATTGTGAGCAGTTCAAAGCTAAAGGGACTACAGGATCATCATTTTCGCCATCTACCCTATCGACTGTATTTGAAGTGTCTCGTCTGTGGCACCTGTTACAATCACAAGCCTAACATAGCGGCGCATCTTCGAACGCGCCACAATATTTACGAACGTGATACGCCGTGGCGTGAACTGCAACCGAAACCACAGTATAATTATGTGATTACGAAAGACAAGGATAAAGATAAAGATAGGGAATCTCGGGGTATATCCTCTCCATCATCATCGCCTACACCTGGCAGCAGTACCGTTAATGTGGGGCGCTCTCTAAAACCGCAGCCTGGCGTGCTGCCCACTCGGCCGGCTGGACTGAATACTTTGGAGGACAGTATTTCATATCATAATGCTGTGGATCTGGACTTTATTACGTACTATTGTCCTAAGTGCAACAAGAATTTTGATTCGCATGCCTTCTGGCGCAAACACATCGTGGAACAGCACAATTACAATAGTCGCCAGGGTCTCAACTTTCGTCAGATCGATATCCATCACTATTTGTGCCTCGAGTGTTATAAGCGTGTGACTGTCACACATACCAAGGGCGCCATCGGCCAGCTGCAGTCACACAAGTTCCGACACTTACCATATCGGTCTTTTAAGTGCTTGACCTGCAATGGGGAATTTGTGCGCAAGCAAATGTTCTTTAAGCACTTGAACCGCGACACAAATCGCTGTGACAACAAACCACTTAGTGCCCAGGATAACGACGATGACGGTGGGGAGCCGCATGAAATCATAGCTAGCGGAGATGTTGCTTCCGCTCGAGCTTTAGAGGAAATTAATCCCGCTGCTTATCGTCTATGGTGTCCTCAATGTGGTGATAACTTTACTACCAGCAGCAAAGCGCTCTGGCGTGAACACATTAACATGTATCATGACCTAGGCAAACGGGAGCTACTCCACATGCGAAAGGTGGGAGACGAACTATATCGCTGCACGGACTGTGACGAACAGTTACAAACCAAGCAACTGCGGGTATTGCAAGAGCATCGCTTCAAACATTTGCCATATGCCGCTTATATACGTTGTCAGATATGCGAACATCAGCAGGATGAACTGGGTCATGGAGCTGTTGCAGCTGGTCTGCACAGTATGCTAGAATTGCAGCAACATATACGCGAAAAGCACACCGACGGAGTCGAGAATGTTGAACAATTACAATCTTTATTAGATGATGAGGACAGTCAGTCAGTAAACAATGAGTCGACTGGTAATGGGCGGTATATGCCGCTGCCACCGCATTTACTGGATGACGATATCGACGATGTGGAATTTGAGGAACAATATCTGCTGGGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEGDGEGDNYNHGNNAPADEFVAEEVEEEEQEGDIDEIDDDGEHDDSRPRGKQKRQEPDDDAIFDFELEPIVNIAESEPEPARRGAVALAPPMPSAPPIRAMQRQSLSSSFGSSLMSRAPGAGAAPTRPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRKGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGDGSAGRKTRVREPRTEPHLAPQPAPIHDDNVGLDVRNEHVETDGVAVVDPNIGLDDDLSRSSLAKRKRINTVAGNGSGSSAADICEDYIHYMCPDCSTECDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCMECKQFVIPNTIKTLRAHKFSHLPQPDWMRCKLCYKSYTEHHELVTHLLKHHHLETLMPDAEESEEPMPSASAGDDSEDNAGNGHGCDDELIHWDEAPRRGGRISSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKATGGAGMSSGSGVSMSVSGQSSTTQTQTPRKQIVTVANETYEIIYLDEDQSPPSNNNINEENDFGEQMQGDDDEFTIGSSNAISGSSRQLPPTAAPNPNRYKCVDCGSLFPTQAALKTHISEEHDFMDTQYSAKKFDNAEPTDEAASASVSTQVPAAASAAIAKTSPTTNSNKKTPQINSSGASTIEQNYIFLCPSCGKAYKTQFEWRRHINDAHNFDKRQYLNMRQLDKYRYQCTQCKDIVSSSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERDTPWRELQPKPQYNYVITKDKDKDKDRESRGISSPSSSPTPGSSTVNVGRSLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEQHNYNSRQGLNFRQIDIHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPLSAQDNDDDGGEPHEIIASGDVASARALEEINPAAYRLWCPQCGDNFTTSSKALWREHINMYHDLGKRELLHMRKVGDELYRCTDCDEQLQTKQLRVLQEHRFKHLPYAAYIRCQICEHQQDELGHGAVAAGLHSMLELQQHIREKHTDGVENVEQLQSLLDDEDSQSVNNESTGNGRYMPLPPHLLDDDIDDVEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00602113;
90% Identity: -
80% Identity: -