Basic Information

Insect: Drosophila innubila
Gene Symbol: -
Assembly: GCA_004354385.1
Location: NW:13852071-13858794[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.00014 0.0076 16.2 0.2 1 23 171 194 171 194 0.96

2 13 0.0014 0.078 13.1 2.9 2 23 243 265 239 265 0.89

3 13 0.17 9.6 6.5 1.2 1 23 373 396 373 396 0.93

4 13 0.12 6.7 7.0 5.9 2 23 445 466 444 467 0.95

5 13 0.0031 0.18 11.9 0.5 1 23 533 556 533 556 0.88

6 13 1.9 1.1e+02 3.2 0.1 2 14 575 587 574 599 0.85

7 13 0.00066 0.037 14.1 3.3 2 23 607 629 607 629 0.96

8 13 0.0014 0.08 13.0 0.1 1 23 737 760 737 760 0.95

9 13 0.0001 0.0059 16.6 0.2 1 23 834 857 834 857 0.92

10 13 0.0011 0.063 13.4 2.2 2 23 907 929 906 929 0.97

11 13 0.0018 0.1 12.7 2.0 1 23 1018 1041 1018 1041 0.92

12 13 0.05 2.8 8.1 1.5 1 21 1093 1113 1093 1114 0.95

13 13 7.6 4.3e+02 1.3 0.1 3 14 1165 1176 1165 1188 0.71

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.00014	0.0076	16.2	0.2	1	23	171	194	171	194	0.96
2	13	0.0014	0.078	13.1	2.9	2	23	243	265	239	265	0.89
3	13	0.17	9.6	6.5	1.2	1	23	373	396	373	396	0.93
4	13	0.12	6.7	7.0	5.9	2	23	445	466	444	467	0.95
5	13	0.0031	0.18	11.9	0.5	1	23	533	556	533	556	0.88
6	13	1.9	1.1e+02	3.2	0.1	2	14	575	587	574	599	0.85
7	13	0.00066	0.037	14.1	3.3	2	23	607	629	607	629	0.96
8	13	0.0014	0.08	13.0	0.1	1	23	737	760	737	760	0.95
9	13	0.0001	0.0059	16.6	0.2	1	23	834	857	834	857	0.92
10	13	0.0011	0.063	13.4	2.2	2	23	907	929	906	929	0.97
11	13	0.0018	0.1	12.7	2.0	1	23	1018	1041	1018	1041	0.92
12	13	0.05	2.8	8.1	1.5	1	21	1093	1113	1093	1114	0.95
13	13	7.6	4.3e+02	1.3	0.1	3	14	1165	1176	1165	1188	0.71

Sequence Information

Coding Sequence: ATGGAAGGTATGGACTTGTGGACGTCCATGTTTTCGACAGACttcgaggaggaggagggagGGGACGGCGAGGGAGATAATTATAATCATGGCAACAACATGCACGCAGACGAGTTTATGTGCGAAGAGATggaggaggcggaggaggCTGAAATAGACGagattgatgatgatgatgttgatcaTCATGATGGGGAACGGGGACATAGAAAGCAAAAGGGACATGAACCTGATGACGATGccatatttgattttgaactGGAGCCTATTATTAGTATTGCTGAGCCAGGACCAGAGTCTGGGCGAAGGGAAAATGCCGCATTGGCGCCACCAATACCATCCGGTCCACCTGTAAGGGCTTCGCATCGTCAGTCGCTGCCAGCATCATTTGGGTCATCCATAATGCCAAGAGGATCGGGTGCTGGGGCAGCTGCAACGCGTCCAACAACATCACAAATCAATGCAACCGATGAAAACGGAGTTccaattaattatgaattgGGTGTCATTTACATTTGTCCTGCTTGCGGAACCGAATATCGACAGCAGGATATGTGGAAGCGTCACATGAACCAAATGCACCAGTATAATACACGGAGAGGCCTCAATTTTGTGGCCATCGATAAGCTGTATCATCGGTGCCTGGAGTGCAACAAGCGGATTGCCATGCACAGTCGGGAAAATCTGCTGAAGCATAAGTTTACCCATTTGCCATATCGGTGCACCAAGTGCTATATATGTAAGCGAGAGTACAAATACAGGCAGGACCTGATGGTGCATCTGCGTATGGTGCACTGTGATGAGGTCGTGGCCATGATGCGGGAAAGCGACGGCACCGCAGGACGAAAGACACGCGTCCGTGAACCGCGCACCGATCCACATTTACCACTTCCAACTGCCCCACTccatgacgatgacgatggaGATGGCGATGGCCTGGAAGTGAGGAATGAACATTTAGATTCGGACGGTGCCGGAGTCGTTGAGCCCAGCGTCAGTTTGGATGACGACCTGAGTCGCAGCTCGTTAGCCAAGCGGAAGCGGAGTAATCCAGTTGCAGGCaacgggaatgggaatggcaGCAGTGCCGCAGACATGTGCGAGGATTACATACACTACATGTGCCCGGAATGCAGCACCGACTGCGAAACTCATGCACAGTGGAGTCAACACATTGAGTTCGTGCACGATTATGTCAGTCGGCGAGGACTCAACTTTCGTTGCGTGGATATGCAGATGCAGTGTCTGGAGTGCAAACAGTTTGTTATACCGAACACGATCAAGACATTGCGGGCTCACAAATTTAGTCATTTGCCGCAGCCGGAATGGATGCGCTGCAAGTTGTGCTACAAGGGCTATACGGAGCATCATGAACTGATAACGCATTTGTTGAAGCATCACCATCTGGAGACTTTAATGCCTGACGTTGAGGAGACGGAGGAGCCGATGCCCAATGCCAATGCCGGAGATGATGGCGAGGATGACTCTGTCAATGATAATGGCAATGGATGCGATGATGAACTGGCGCATTGGGACGAAGCACCACGTCGAGGCGGTCGCATAAGTAGCGATGATATGTACGAACCTCACATTGACTATCTGTGTCCACAGTGCGGCAGGGAATTCATCGAGAAAAAACACTGGCGCACTCATGTCGTTCAAGTTCATGGAATGAACGATTTGGCCAAGTTAAACTTTGAAGTGATCAACGATAGGCAATTGAAATGCACCGAATGCGACAAGATCATCACGAATGCATACGGCATACAGAATGCCCAACAACATCGGATTACGCATCTGCCGTACAAGGCATACGCACGCTGTCGCAAGTGCCATAAATCGTATACGGATCGCAAGGGTTTGGTCAAGCACTTGGCCACATATCATCGTGTTGGATACGAGCCGCGTAGAGTGGCTGGAGGTGCTGGAATGAGTACGGGCAGCGGCTTGGGCATTTCTGCAAGTGGCCCGGCATCATCCAAGTCGCAGACGCCGCGTAAACAAATTGTCACGGTGGCAAATGAAACATACGAGATTATATATTTGGACGAGGAGCAATCATCGCCCAGTAGCAATAACATTAACGAGGAGAACGATTTTGGCGAACAAATGCAAGGAGATGATGATGAATATGTCACCAGTTTAAGCAGTCGTCAGTTGCCGCCAGCTGTTACTCCCAATCCGAATCCCACTTCCAATCTCAATCGCTACAAGTGCGTTGACTGCGGCTCCTTGTTTCCCACACAGGTGGCACTCAAAACGCACATTAGCGAGGAGCACGATTTTATGGATACACAATATAGTGCCAAGAAGTTTGACAACTCCGAACCGACTGATGAAGTTGCTTCCGTTTCCACATCTGCATCCGCTTCGGCTTCTACTCAAGTGCCTGTGGCAGCATCGATTGCCACAGCAAAGACATCAACACCCTCAAGTAGCAGTAAGAAAATAGCACAAATCAATAGCTCAGGTGCATCGACAATAGagcaaaattatatattccTGTGTCCATCGTGCGGAAAGGCGTACAAGACACAGTTTGAGTGGCGTCGTCACATCAATGATGCCCACAATTTCGACAAGCGTCAATATTTGAATATGCGCCAGTTGGATAAGTATCGTTATCAGTGTACTCAGTGCAGGGATATTGTGAGCAGTTCAAAATTAAAGGGTCTCCAGGATCATCACTTTCGCCATCTTCCCTATCGACTGTATTTGAAGTGTCTCGTCTGTGGCACCTGTTACAATCACAAGCCCAACATTGCGGCTCATCTGCGTACACGTCATAATATCTACGAACGGGATACGCCGTGGCGTGAGCTGCAGCCTAAACCACAGTACAACTATGTGATTATGAAAGACAAGGATAAGGATGCGGAATCTCGCGGTATTTCaccgtcatcatcatcgccgACACCTGGCAGTAGTAGCATTAATTTGGGACGCTCGCTTAAAGCACAGCCTGGTGGTCTGCCGACTCGACCGGCTGGACTGAATACGTTAGAGGATAGCATTTCATATCATAATGCTGTGGATATGGACTTTATCACGTACTACTGTCCCAAGTGCAACAAGAACTTTGATTCGCATGCCTTCTGGCGCAAACACATCGTGGAACAGCACAATTTCAACAGTCGTCAGGGTCTGAACTTTCGTCAGATCGATATGCATCACTATTTGTGCCTCGAGTGCTACAAGCGGGTGACTGTCACCCATACAAAGGGGGCCATCGGGCAGCTGCAGTCGCACAAGTTCCGACACTTGCCCTATCGCTCTTTCAAATGCTTGACCTGCAATGGAGAATTTGTGCGCAAGCAAATGTTCTTCAAACACTTGAATCGAGAAACAAATCGCTGTGACAACAAACCACTCAGTGACCatgacaacgacaatgatGGCGCAGAGCAGCATGAGACAATTGTCGGAGAAAATGCtattgatgctgctgcttcaGCTGTAGTGGAAGTCGATCCCGCTGCATATCAGCTATGGTGTCCCCAATGTGGCGACAAGTTTATCACCAGCAGTAAAGCGCTCTGGCGTGAACACATCATCGCGAATCATGGCCTCGGCAAGCGAGAGATGCTCCATATGCGAAAAGTGGTTGATGATCTGTACCACTGCACGGACTGTGACGAGCAGTTGCAAACAAAGCATCTAAGGGTGCTGCAGGAACATCGCTTTAAACACCTGCCCTATGCCGCCTATATACGCTGCCAGCTATGCGAGAATCAGCAGGATGAACTGGGTCATGGGGCTGTTGCAGCTGGTCTGCACAGTATGCAAGAGTTGCAGCAACACATACGCGACAAGCATCCCGACGTATCCGAGAATGATGAGCAAATGCTGTCGCTACTAGATGATGAGGACATCCAGCTGGCAAACAATGAGTCGACTGGCAATGGCCGATATATGCCGCTTCCGCCGCATTTGCTGGATGACGATGCTGATGACATGGATTTTGAGGCACAGTATCTGCTAGGTTAG
Protein Sequence: MEGMDLWTSMFSTDFEEEEGGDGEGDNYNHGNNMHADEFMCEEMEEAEEAEIDEIDDDDVDHHDGERGHRKQKGHEPDDDAIFDFELEPIISIAEPGPESGRRENAALAPPIPSGPPVRASHRQSLPASFGSSIMPRGSGAGAAATRPTTSQINATDENGVPINYELGVIYICPACGTEYRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRESDGTAGRKTRVREPRTDPHLPLPTAPLHDDDDGDGDGLEVRNEHLDSDGAGVVEPSVSLDDDLSRSSLAKRKRSNPVAGNGNGNGSSAADMCEDYIHYMCPECSTDCETHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKTLRAHKFSHLPQPEWMRCKLCYKGYTEHHELITHLLKHHHLETLMPDVEETEEPMPNANAGDDGEDDSVNDNGNGCDDELAHWDEAPRRGGRISSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRRVAGGAGMSTGSGLGISASGPASSKSQTPRKQIVTVANETYEIIYLDEEQSSPSSNNINEENDFGEQMQGDDDEYVTSLSSRQLPPAVTPNPNPTSNLNRYKCVDCGSLFPTQVALKTHISEEHDFMDTQYSAKKFDNSEPTDEVASVSTSASASASTQVPVAASIATAKTSTPSSSSKKIAQINSSGASTIEQNYIFLCPSCGKAYKTQFEWRRHINDAHNFDKRQYLNMRQLDKYRYQCTQCRDIVSSSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERDTPWRELQPKPQYNYVIMKDKDKDAESRGISPSSSSPTPGSSSINLGRSLKAQPGGLPTRPAGLNTLEDSISYHNAVDMDFITYYCPKCNKNFDSHAFWRKHIVEQHNFNSRQGLNFRQIDMHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRETNRCDNKPLSDHDNDNDGAEQHETIVGENAIDAAASAVVEVDPAAYQLWCPQCGDKFITSSKALWREHIIANHGLGKREMLHMRKVVDDLYHCTDCDEQLQTKHLRVLQEHRFKHLPYAAYIRCQLCENQQDELGHGAVAAGLHSMQELQQHIRDKHPDVSENDEQMLSLLDDEDIQLANNESTGNGRYMPLPPHLLDDDADDMDFEAQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00602113;
90% Identity: iTF_00507183;
80% Identity: -