Basic Information

Insect: Drosophila rubida
Gene Symbol: -
Assembly: GCA_035046165.1
Location: JAWNOF010000012.1:25810346-25814335[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00044 0.026 14.8 0.1 1 23 183 206 183 206 0.96

2 14 0.0015 0.089 13.1 2.9 2 23 255 277 251 277 0.89

3 14 0.45 27 5.3 0.8 1 23 372 395 372 395 0.92

4 14 0.43 25 5.4 5.6 2 23 444 466 443 467 0.95

5 14 0.0034 0.2 12.0 0.5 1 23 532 555 532 555 0.88

6 14 2.1 1.2e+02 3.2 0.1 2 14 574 586 573 598 0.85

7 14 0.00073 0.043 14.1 3.3 2 23 606 628 606 628 0.96

8 14 0.00096 0.057 13.7 0.1 1 23 729 752 729 752 0.95

9 14 0.00011 0.0067 16.6 0.2 1 23 813 836 813 836 0.92

10 14 0.0012 0.072 13.4 2.2 2 23 886 908 885 908 0.97

11 14 0.0019 0.11 12.7 2.0 1 23 997 1020 997 1020 0.92

12 14 0.055 3.3 8.2 1.5 1 21 1072 1092 1072 1093 0.95

13 14 0.094 5.5 7.4 0.3 2 23 1146 1170 1145 1170 0.89

14 14 1.8 1e+02 3.4 0.3 1 14 1188 1200 1188 1212 0.72

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00044	0.026	14.8	0.1	1	23	183	206	183	206	0.96
2	14	0.0015	0.089	13.1	2.9	2	23	255	277	251	277	0.89
3	14	0.45	27	5.3	0.8	1	23	372	395	372	395	0.92
4	14	0.43	25	5.4	5.6	2	23	444	466	443	467	0.95
5	14	0.0034	0.2	12.0	0.5	1	23	532	555	532	555	0.88
6	14	2.1	1.2e+02	3.2	0.1	2	14	574	586	573	598	0.85
7	14	0.00073	0.043	14.1	3.3	2	23	606	628	606	628	0.96
8	14	0.00096	0.057	13.7	0.1	1	23	729	752	729	752	0.95
9	14	0.00011	0.0067	16.6	0.2	1	23	813	836	813	836	0.92
10	14	0.0012	0.072	13.4	2.2	2	23	886	908	885	908	0.97
11	14	0.0019	0.11	12.7	2.0	1	23	997	1020	997	1020	0.92
12	14	0.055	3.3	8.2	1.5	1	21	1072	1092	1072	1093	0.95
13	14	0.094	5.5	7.4	0.3	2	23	1146	1170	1145	1170	0.89
14	14	1.8	1e+02	3.4	0.3	1	14	1188	1200	1188	1212	0.72

Sequence Information

Coding Sequence: ATGGAAGGTATGGATCTGTGGACGTCTATGTTTTCGGCTGACTTTGAGGAGGGCGATGGTGTGGGTGATAATTACAATCATGACAGCAACGCGCATGCAGACGAGTTTATTGGCGAGGAAGAAGAGGAGGAGGTGGATGAGGAACAGGAGCAGGAGGCTGATATCGATGAGCTGGATgacgaaagagagagcgagagggagaaagaggGTGACGACAgtagacgacggcgacgtaGCAAGCAGCAGAAAGGAAATGAgcctgatgatgatgccataTTTGATTTCGAGCTGGAGCCCATTGTTAGCATTGCTGAACCAGAATTGGAACCTGTGCGTCGAGAAACTGTGGCCTTAGCGCCACCAATGCCAACGGGACCGCCAGTACGTGCCATGCATCGTCAATCACTGCCAGCCTCATTCGGTTCATCGCTAATGCCACGAGGAGGATCTGTTGTGGGTGCAACTCCTCCAACGCGGCCCACAACGTCGCAAATCAACGCCACCGATGAAAATGGTGTTCCCATAAACTACGAATTGGGCGTTATTTACATTTGTCCGGCATGCGGCGCCGAGTATCGACAGCAGGACATGTGGAAGCGTCACATGAATCAGATGCACCAGTATAACACGCGCAAGGGCCTGAATTTCGTGGCCATCGATAAACTGTATCATCGGTGTCTGGAGTGCAATAAGCGCATTGCGATGCACAGTCGAGAGAATCTGTTGAAGCACAAGTTCACCCATTTGCCATATCGTTGCACCAAATGCTACATTTGCAAACGAGAGTACAAATACAGGCAGGACCTGATGGTGCATCTGCGCATGGTCCACTGTGACGAGGTGGTGGCCATGATGCGAGACGGCGACACCAGTGCCGGCCGCAAGACACGTGTGCGCGAGCCACGCACCGAGCCGCACTCAAGCCAACAAACTGCTGAAGCTTTTGACGATGACGATATTATACAAGTGAAAAGCGAGCACGCGGAAACGGATGCTGCTACGACAGAGGATGATGCTGTGACtggcagcacacacaagcgGAAGCGCAGCaatccagcagctgcagtagACAATGGAACCAGTGCTGCTGAAATCTGCGAGGATTACATTCACTACATGTGCCCGGACTGCGCCACCGATTGCGACACTCATGCGCAGTGGAGTCAGCACATTGAGTTCGTGCACGATTATGTCAGCAGACGAGGGCTCAACTTTCGCTGCGTGGACATGCAGATGCAGTGCCTGGAGTGCAAGCAGTTTGTCATCCCGAATACGATTAAGACTTTGCGTGCTCACAAGTTTAATCATTTGCCGCAACCCAATTGGATGCGCTGTAAATTGTGCTACAAAGGTTACACGGAGCATCACGAGCTGGTGACGCATCTGCTCAAGCAGCATCACTTGGAGTCGTTAATGCCCGACGCCGAGGAGACGGAGGAGCCCGTCTCCAGTGCTAGTGGCGGGGACGATGGCGAAGATAGAGCTGGGAATGGCACCGGCAATTGCTGCGACGAGGAATTGACACATTGGGATGAAGCACCACGTCGTGGCGGACGCATCAGCAGCGATGACATGTACGAACCACACATTGACTATCTCTGTCCACAGTGCGGCAGAGAGTTCATTGAGAAGAAACACTGGCGCACCCACGTCGTCCAGGTGCACGGCATGAACGATCTGGCCAAGCTCAATTTTGAAGTAATCAATGACAGACAGCTGAAATGCACGGAATGCGACAAGATCATCACAAATGCGTATGGCATACAGAATGCGCAACAGCACCGCATTACGCACTTGCCATACAAGGCGTATGCGCGGTGTCGCAAGTGCCACAAATCGTACACGGATCGCAAGGGGCTGGTCAAGCATTTGGCCACATATCATCGTGTAGGCTACGAGCCGCGTAAGGCAGCTGGTGCTGGCACGAGTGCGGGCGGCAGTCAGACTCCAAAGGCACAGACGCCgcgcaaacaaattgtaactGTGGCCAATGAAACTTATGAGATTATCTACTTGGATGAGGAGCAATCGTCgcccggcaacaacaacattaatgaGGAAAATGATTTTGGTGAACAGATGCAAGGCGATGACGACGAATATGGAATCAGTAATAGTGCCatcagtagcagcaacagtcgccagTTGTCGTCAAGTGCCATGCCCAATCACAACCCCAATCGTTACAAGTGCGTTGACTGCGGCTCGTTGTTTCCAACACAAGCGGCACTCAAGACGCACATTAGCGAGGAGCATGACTTTATGGATACTCACTACAGTGCCAAAAAGTTTGACAACGCCGAACCGACTGATGAGACAGCTCCGGTCTCGGCTTCAGCGCCTGCATCAGCGTCCACAGCGAAGACGTCCCCGGGCAGTAAGAAGACGACATTATTGAATCCATCGGGCGCCTCAACCATTGAGCAAAACTATATATTCCTGTGTCCGTCCTGTGGCAAGGCCTACAAGACGCAGTTTGAGTGGCGGCGCCACATTAACGATGCCCACAACTTCGACAAGCGGCAGTACTTGAATATGCGTCAGTTGGACAAGTATCGGTATCAGTGCACTCAGTGCAAGGATATTGTCAGCAGCTCGAAGCTAAAGGGTCTGCAGGATCATCATTTCCGCCACCTGCCCTATCGCCTGTATCTGAAGTGTCTCGTCTGCGGCACTTGCTACAATCACAAGCCCAACATAGCGGCGCATCTGCGAACGCGGCACAACATCTACGAACGCGATACGCCGTGGCGTGAGTTGCAGCCGAAGCCACAGTACAACTATGTGATAATGAAAGACAAGGACAAAGATAAGGAGGCTCGTGGCATTTCCTCCTCGCCATCGTCGCCAACACCTGGCAGCAGTAGCTGTAATGCAGGACGCTCCCTAAAACCGCAGCCAGGCCTGTTGCCCACTCGACCAGCTGGACTGAATACGCTGGAGGATAGCATTTCATATCACAACGCTGTGGATTTGGACTTCATCACGTACTATTGTCCCAAATGCAATAAGAACTTTGATTCGCATGCATTCTGGCGCAAGCACATTGTGGAAcagcacaactacaacagtcGCCAGGGGCTGAATTTTCGCCAAATCGACATTCATCACTATTTGTGCCTAGAGTGCTATAAACGTGTAACTGTCACCCACACCAAGGGCGCTATTGGCCAGTTGCAATCACACAAGTTCCGACATCTGCCATACCGATCTTTCAAGTGCCTGACCTGCAATGGTGAATTTGTGCGCAAACAAATGTTCTTCAAGCACCTGAATCGCGACACAAATCGCTGTGACAACAAGCCTTTGAGTGCACAGGAAACCGACGACGATGGTGGAGAGGCGGCAGAGAGTTCAGCCGGTGTCGTTAGCGTTGATGGTGGActcccagctgctgctgccttggaGGAAGTTGACCCTGCTGCCTATCGCCTGCGGTGTCCGCAATGCGGCGACAACTTTACCACAAGCAGTAAAGCGTTGTGGCGCAAACACATTAACATCTACCATGGTCTGGGCAAGCGGGAGCAGCTGCATATGCGTAAGATTGGCGAGGAGCTCTATCGCTGCACGGACTGTGACGAGGAGTTGCAATCGAAACAGTTGCGGGTGCTACAGGAACATCGCTTTCGGCATTTGCCCTATGCGGACTACATTCGATGTCAGCTATGCGAACAGCAGACGGATGAACTGGGTCACGGGGCTGCTGCAGCCGGTCTGCACAGTATGCTCGAGTTGCAGCAACACATACGCGAAAAACATCCAGACTTGGCTGAGAGTGACGAACAAATGGAAACGCTtcttgatgatgatgacgacagTCAACCTGCGAACAATGAGTCGGCAGGCAATGGACGTTACATGCCGCTACCGCCGCATTTACTGGACGACGATGACATGGAATTTGAGGACCAGTATCTGCTTGGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEGDGVGDNYNHDSNAHADEFIGEEEEEEVDEEQEQEADIDELDDERESEREKEGDDSRRRRRSKQQKGNEPDDDAIFDFELEPIVSIAEPELEPVRRETVALAPPMPTGPPVRAMHRQSLPASFGSSLMPRGGSVVGATPPTRPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRKGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRDGDTSAGRKTRVREPRTEPHSSQQTAEAFDDDDIIQVKSEHAETDAATTEDDAVTGSTHKRKRSNPAAAVDNGTSAAEICEDYIHYMCPDCATDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKTLRAHKFNHLPQPNWMRCKLCYKGYTEHHELVTHLLKQHHLESLMPDAEETEEPVSSASGGDDGEDRAGNGTGNCCDEELTHWDEAPRRGGRISSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKAAGAGTSAGGSQTPKAQTPRKQIVTVANETYEIIYLDEEQSSPGNNNINEENDFGEQMQGDDDEYGISNSAISSSNSRQLSSSAMPNHNPNRYKCVDCGSLFPTQAALKTHISEEHDFMDTHYSAKKFDNAEPTDETAPVSASAPASASTAKTSPGSKKTTLLNPSGASTIEQNYIFLCPSCGKAYKTQFEWRRHINDAHNFDKRQYLNMRQLDKYRYQCTQCKDIVSSSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERDTPWRELQPKPQYNYVIMKDKDKDKEARGISSSPSSPTPGSSSCNAGRSLKPQPGLLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEQHNYNSRQGLNFRQIDIHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPLSAQETDDDGGEAAESSAGVVSVDGGLPAAAALEEVDPAAYRLRCPQCGDNFTTSSKALWRKHINIYHGLGKREQLHMRKIGEELYRCTDCDEELQSKQLRVLQEHRFRHLPYADYIRCQLCEQQTDELGHGAAAAGLHSMLELQQHIREKHPDLAESDEQMETLLDDDDDSQPANNESAGNGRYMPLPPHLLDDDDMEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00602113;
90% Identity: iTF_00595499;
80% Identity: -