Basic Information

Insect: Drosophila histrio
Gene Symbol: -
Assembly: GCA_958299025.2
Location: OY282581.2:21340838-21344892[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00045 0.035 14.8 0.1 1 23 163 186 163 186 0.96

2 14 0.0016 0.12 13.1 2.9 2 23 235 257 231 257 0.89

3 14 0.14 11 7.0 1.3 1 23 355 378 355 378 0.93

4 14 0.23 18 6.3 5.8 2 23 427 448 426 449 0.95

5 14 0.0036 0.28 12.0 0.5 1 23 515 538 515 538 0.88

6 14 2.2 1.7e+02 3.2 0.1 2 14 557 569 556 581 0.85

7 14 0.00075 0.059 14.1 3.3 2 23 589 611 589 611 0.96

8 14 0.0016 0.13 13.1 0.1 1 23 706 729 706 729 0.95

9 14 0.00012 0.0093 16.7 0.2 1 23 796 819 796 819 0.92

10 14 0.0013 0.099 13.4 2.2 2 23 869 891 868 891 0.97

11 14 0.0036 0.28 12.0 3.8 1 23 980 1002 980 1003 0.94

12 14 0.057 4.5 8.2 1.5 1 21 1055 1075 1055 1076 0.95

13 14 3.9 3.1e+02 2.4 1.9 3 23 1117 1140 1117 1140 0.89

14 14 1.3 99 4.0 1.1 1 23 1158 1182 1158 1182 0.81

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00045	0.035	14.8	0.1	1	23	163	186	163	186	0.96
2	14	0.0016	0.12	13.1	2.9	2	23	235	257	231	257	0.89
3	14	0.14	11	7.0	1.3	1	23	355	378	355	378	0.93
4	14	0.23	18	6.3	5.8	2	23	427	448	426	449	0.95
5	14	0.0036	0.28	12.0	0.5	1	23	515	538	515	538	0.88
6	14	2.2	1.7e+02	3.2	0.1	2	14	557	569	556	581	0.85
7	14	0.00075	0.059	14.1	3.3	2	23	589	611	589	611	0.96
8	14	0.0016	0.13	13.1	0.1	1	23	706	729	706	729	0.95
9	14	0.00012	0.0093	16.7	0.2	1	23	796	819	796	819	0.92
10	14	0.0013	0.099	13.4	2.2	2	23	869	891	868	891	0.97
11	14	0.0036	0.28	12.0	3.8	1	23	980	1002	980	1003	0.94
12	14	0.057	4.5	8.2	1.5	1	21	1055	1075	1055	1076	0.95
13	14	3.9	3.1e+02	2.4	1.9	3	23	1117	1140	1117	1140	0.89
14	14	1.3	99	4.0	1.1	1	23	1158	1182	1158	1182	0.81

Sequence Information

Coding Sequence: ATGGAAGGTATGGACTTGTGGACGTCCATGTTTTCGGCTGACTTTGAGGAGGGGGACGGCGAGGGAGACAATTATAATCATGGCAACGCGGACGAGTTTATGGccgaagaggaggaggagggcgATATTGACGAGGTGGATGATGATGAAGGGGAGGGAGATGACATTAGGCGTCGCAGGAAGCAAAAGGGACATGAGCCTGATGACGATGCCATATTTGATTTCGAACTGGAGCCTATTGTTAATATTGCTGAACCAGAACCAGAAGTAGAACCAGCAAGAAGAGGAACTGTCGCCTTGGCGCCCCCAATTCCATCCGGGCCACCTGTAAGGGCTGTACACCGACAGTCATTGCCTGCGTCATTTGGTTCATCACTTATGCCTCGAGGATCTGGTGCAGTAGCAGCTCCAACGCGTCCAACGACTTCACAAATCAATGCCACCGATGAAAACGGAGTTctaattaattatgaattGGGCGTTATTTACATATGTCCCGCATGCGGCGCCGAATATCGCCAACAGGATATGTGGAAGCGTCACATGAACCAAATGCATCAGTATAATACACGCAAGGGCCTCAATTTTGTTGCCATCGATAAGTTGTATCATCGGTGCCTGGAGTGCAACAAGCGCATTGCCATGCACAGTAGGGAGAATCTGCTGAAGCATAAGTTTACCCATTTGCCATATCGGTGCACCAAGTGCTATATATGTAAGCGAGAGTACAAATACAGGCAGGACCTGATGGTGCATCTGCGGATGGTGCACTGTGATGAAGTAGTTGCAATGATGCGGGAAGGCGATGGCAGCGCCGGGCGGAAGACGCGTGTGCGTGAACCGCGTACCGAGATACATCCACCACTTCAAACTGCCCCAGTgaatgacgatgacgatgccATAGAAGTGAGGAACGAACGTGTGGAGGCGGACAATGGCGCAGGCGTTGAAGCAAACATCGTTTTGGATGACGATCTGAGTCGCAAACGAAAGCGTGGTAATGCAGTTGCAGGCAATGGGAATGGCAGTAGTGCTGCAGACATATGTGAGGATTACATACACTACATGTGCCCGGACTGCAGTACCGATTGCGACACTCATGCACAGTGGAGCCAACACATTGAGTTCGTGCACGATTATGTCAGCAGGCGAGGACTCAACTTTCGATGCGTGGACATGCAGATGCAGTGCCTGGAGTGCAAAAAGTTTGTCATACCGAACACAATCAAAACACTTCGTGCCCACAAGTTTAGTCACTTGCCGCAGCCGGAATGGATGCGCTGCAAGTTGTGCTACAAGGGTTATACGGAGCACCACGAGCTGGTTACGCATCTGCTCAAGCATCACCATCTAGAGACTTTGATGCCCGACGCTGAAGAGACGGAGGAGCCAATGCCCATTGCCAGTGCAGGAAATGATGGCGAGGATATCGCAGGCAATGCCAACGACAATGATTGCGATGATGAACTGTCACATTGGGACGAGGCACCACGTCGAGGTGGTCGCATAAGTAGCGATGATATGTATGAACCTCATATTGACTATCTATGTCCGCAGTGCGGCAGGGAGTTCATTGAGAAGAAACATTGGCGCACTCATGTCGTACAAGTGCACGGAATGAACGATCTGGCCAAGTTGAACTTTGAAGTGATCAACGATAGACAATTGAAATGCACTGAATGTGACAAGATCATCACGAATGCTTATGGAATACAGAACGCCCAACAACATCGGATTACGCATTTGCCGTACAAGGCGTACGCACGTTGCCGCAAGTGCCACAAATCGTACACGGACCGCAAGGGATTGGTCAAGCACTTGGCCACATATCATCGTGTGGGATACGAACCGCGTAAAGTTGCTGGAGGATCGGGCAGCAGTGGGAATGCGTCTGCAAATAGCCAGGCAACAAAGTCGCCGCGTAAACAAATTGTCACCGTGgcaaatgaaacatatgaGATTATATATTTGGATGAGGAGCAATCATCGCCCAGTAACAATAACATCAACGAGGAGAACGATTTTGGGGAGCAAATGCAGGGAGATGATGATGAATATGGCACCAGCTCCAACAGTCGTCAGATGTCGCCAGCGGTTGCTCCCAATCCCAATCGCTATAAGTGCGTTGATTGCGGCTCCTTGTTTCCAACACAAGTGGCACTCAAGACGCACATTAGCGAGGAGCATGATTTTATGGATTCACAATACAGTGCCAAAAAGTTTGATAACGCTGAACCGACTGATGAcgcagcttcagtttcagtttcagcttcagcGGCAACTCAAGGGCCAGCGGCAGAAAAAACGCCGCCAGCCACAAGTGGAGGCAAGAAGACAGCACAAGTAAATAATTCTGGTGCATCGACCAtagaacaaaattatatatttctgtgTCCTTCGTGTGGCAAGGCATACAAGACACAGTTTGAGTGGCGTCGTCACATCAATGATGCGCACAATTTCGACAAGCgtgaatatttgaatatgcGTCAGCTGGACAAGTATCGTTATCAGTGTACTCAATGCAAGGATATTGTGAGCAGCTCGAAGCTAAAGGGTCTGCAGGATCATCACTTTCGCCATCTACCCTATCGACTGTATCTGAAGTGTCTCGTCTGCGGCACATGTTACAATCACAAGCCCAACATTGCGGCACATCTGCGTACGCGCCACAATATCTACGAACGTGATACGCCGTGGCGTGAGCTGCAGCCTAAACCGCAGTACAACTATGTGATTATGAAAGACAAGGATAAAGAAGGGGAATCTCGCGGCGTATCCTCCCCATCAACATCGCCGACACCTGGCAGCAGTAGCATGAATGTTGGACGCTCGCTTAAACCGCAGCCTGGCCTGTTGCCCACTCGTCCTGCTGGACTGAATACGTTGGAGGACAGCATTTCATATCACAATGCTGTGGATATGGACTTCATCACGTACTATTGTCCCAAGTGTAACAAGAACTTTGATTCGCACGCCTTCTGGCGCAAACACATCGTCGAACATCATAATTACAACAGTCGCCAGGGTCTCAATTTTCGTCAGATCGATATGCATCACTATTTGTGCCTCGAGTGCTACAAGCGGGTGACTGTCACCCACACCAAGGGCGCCATCGGCCAGCTGCAGTCGCACAAGTTCCGACACTTACCCTATCGCTCCTTCAAGTGCTTGACCTGCAATGGTGAATTTGTGCGCAAACAAATGTTCTTTAAGCACTTGAATCGCGACACAAATCGTTGTGACAACAAACCAATCATTGCCCAGGACAACGACGATGATGCTGCGGAGCAGCATGAGAATATTGCCGCTGTACTTGAAATTGATCCAGCTTCATATCGCTTGTGGTGTCCCCAATGTGGTGATAACTTTATTACTAGCAGCAAAGCGCACTGGCGTGAACACATTAATATGTGTCATGGCCTCGGCAAGCGAGAACAGCTTCATATGCGAAAAGTGGGTGAGGATCTGTATCGCTGCACGGACTGTGATGAACAGTTGCAAACGAAGCAGCTGCGAATGCTGCAGGATCATCGCTTCAGACATCTGCCCTATGCCGCGTATATACGCTGCCAGCTTTGCGAACATCAGCATGATGAATTGGGTCATGGGGCTGTTGCAGCTGGTCTGCACAGCATGCAGGAGTTGCAGCAACACATACGCGACCAGCATCCCGATGCGACCGAGAATTATGAACAAATTCAATCGCTACTGGACAATGAGGACAGCCAGCAGGTGAACAATGAATCAACTGGCAATGGCCGGTATATGCCACTGCCGCCGCATTTGCTCGATGACGATGTCGACGACATGGAATTTGAGGGACAGTATCTGCTGGGCTGA
Protein Sequence: MEGMDLWTSMFSADFEEGDGEGDNYNHGNADEFMAEEEEEGDIDEVDDDEGEGDDIRRRRKQKGHEPDDDAIFDFELEPIVNIAEPEPEVEPARRGTVALAPPIPSGPPVRAVHRQSLPASFGSSLMPRGSGAVAAPTRPTTSQINATDENGVLINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRKGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGDGSAGRKTRVREPRTEIHPPLQTAPVNDDDDAIEVRNERVEADNGAGVEANIVLDDDLSRKRKRGNAVAGNGNGSSAADICEDYIHYMCPDCSTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKKFVIPNTIKTLRAHKFSHLPQPEWMRCKLCYKGYTEHHELVTHLLKHHHLETLMPDAEETEEPMPIASAGNDGEDIAGNANDNDCDDELSHWDEAPRRGGRISSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKVAGGSGSSGNASANSQATKSPRKQIVTVANETYEIIYLDEEQSSPSNNNINEENDFGEQMQGDDDEYGTSSNSRQMSPAVAPNPNRYKCVDCGSLFPTQVALKTHISEEHDFMDSQYSAKKFDNAEPTDDAASVSVSASAATQGPAAEKTPPATSGGKKTAQVNNSGASTIEQNYIFLCPSCGKAYKTQFEWRRHINDAHNFDKREYLNMRQLDKYRYQCTQCKDIVSSSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERDTPWRELQPKPQYNYVIMKDKDKEGESRGVSSPSTSPTPGSSSMNVGRSLKPQPGLLPTRPAGLNTLEDSISYHNAVDMDFITYYCPKCNKNFDSHAFWRKHIVEHHNYNSRQGLNFRQIDMHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPIIAQDNDDDAAEQHENIAAVLEIDPASYRLWCPQCGDNFITSSKAHWREHINMCHGLGKREQLHMRKVGEDLYRCTDCDEQLQTKQLRMLQDHRFRHLPYAAYIRCQLCEHQHDELGHGAVAAGLHSMQELQQHIRDQHPDATENYEQIQSLLDNEDSQQVNNESTGNGRYMPLPPHLLDDDVDDMEFEGQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00602113;
90% Identity: -
80% Identity: -