Basic Information

Insect: Drosophila neotestacea
Gene Symbol: -
Assembly: GCA_035044365.1
Location: JAWNMD010000456.1:2463339-2467813[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.00044 0.034 14.8 0.1 1 23 168 191 168 191 0.96

2 13 0.0015 0.12 13.1 2.9 2 23 240 262 236 262 0.89

3 13 0.013 1 10.1 0.9 1 23 362 385 362 385 0.93

4 13 0.68 52 4.8 6.1 2 23 434 455 433 456 0.95

5 13 0.0035 0.27 12.0 0.5 1 23 523 546 523 546 0.88

6 13 2.1 1.6e+02 3.2 0.1 2 14 565 577 564 589 0.85

7 13 0.00074 0.057 14.1 3.3 2 23 597 619 597 619 0.96

8 13 0.0016 0.12 13.1 0.1 1 23 728 751 728 751 0.95

9 13 0.00012 0.0089 16.6 0.2 1 23 813 836 813 836 0.92

10 13 0.0012 0.095 13.4 2.2 2 23 886 908 885 908 0.97

11 13 0.0035 0.27 12.0 3.8 1 23 997 1019 997 1020 0.94

12 13 0.056 4.3 8.2 1.5 1 21 1072 1092 1072 1093 0.95

13 13 0.52 40 5.1 0.6 3 23 1137 1159 1135 1160 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.00044	0.034	14.8	0.1	1	23	168	191	168	191	0.96
2	13	0.0015	0.12	13.1	2.9	2	23	240	262	236	262	0.89
3	13	0.013	1	10.1	0.9	1	23	362	385	362	385	0.93
4	13	0.68	52	4.8	6.1	2	23	434	455	433	456	0.95
5	13	0.0035	0.27	12.0	0.5	1	23	523	546	523	546	0.88
6	13	2.1	1.6e+02	3.2	0.1	2	14	565	577	564	589	0.85
7	13	0.00074	0.057	14.1	3.3	2	23	597	619	597	619	0.96
8	13	0.0016	0.12	13.1	0.1	1	23	728	751	728	751	0.95
9	13	0.00012	0.0089	16.6	0.2	1	23	813	836	813	836	0.92
10	13	0.0012	0.095	13.4	2.2	2	23	886	908	885	908	0.97
11	13	0.0035	0.27	12.0	3.8	1	23	997	1019	997	1020	0.94
12	13	0.056	4.3	8.2	1.5	1	21	1072	1092	1072	1093	0.95
13	13	0.52	40	5.1	0.6	3	23	1137	1159	1135	1160	0.88

Sequence Information

Coding Sequence: ATGGAAGGTATGGACTTATGGACGTCCATGTTTTCGACCGACTTTGAGGAGGGCGATGGCGACGGTGAGGGGGATAGCTACAACAATAACGCGCAGGCAGACGTGTTTATGGGTGAAGAGGAGGGTGAGGAGGAGGACCAGGAGGGTGATATAGACGAgattgatgatgatggggaGGGTGATGATAGTAGGCGTCGTCAGGGGAAGCGAAAGAGACATGAgcctgatgatgatgccaTATTTGATTTCGAATTGGAGCCTATTGTTAATATTGCTGAGCCACAACCAGAACGGAGAGGAACTGTCGCATTGGCGCCCCCAATGCCATCTGGACCACCTGTAAGGGGAATGCATCACCGTCAATCATTGCCAGCATCGTTTGGATCCGCATTAATGCCACGAGGAACTGGTGCAGGAACAGCTCCAACACGACCAACGACTTCACAAATCAATGCCACCGATGAGAATGGTGTTCCaattaattatgaattggGAGTTATTTACATATGTCCTGCATGCGGAGCCGAATATCGACAGCAGGATATGTGGAAGCGTCACATGAACCAAATGCATCAGTATAATACACGAAAAGGTCTCAATTTTGTGGCGATCGATAAGCTGTATCATCGGTGCCTTGAGTGCAACAAGCGGATTGCGATGCACAGTAGAGAGAATCTTCTCAAGCATAAGTTTACCCATTTGCCATATCGGTGCACCAAGTGCTATATATGTAAGCGAGAGTACAAATACAGGCAGGACCTGATGGTGCATCTGCGTATGGTGCACTGTGATGAAGTAGTTGCCATGATGCGGGAAGGCGACGGCACAGCTGGAAGAAAGACGCGTGTCCGTGAACCACGTACCGAGCAACATCTCACTCTTCAACCTCCCCCAATCCATGACGATGACGATTGCCTAGAAGTAAGGAATGAACAAGTTGAAACAGATGGTCCTGCAGGCACTGAGGCCAACATCGGTTTGGATGACGATCCGAGCTCATTAGCAAAACGGAAACGTAGTAATCCAGGTacaggaaatggaaatggcaatAGTGCTGCAGATATGTGTGAAGACTACATACACTACATGTGCCCGGATTGCGGCACAGACTGTGACACTCATGCTCAGTGGAGTCAACACATTGAATTCGTTCACGATTATGTGAGTAGGCGAGGTCTCAACTTCCGATGCGTCGATATGCAGATGCAGTGCCTGGAGTGCAAACAGTTTGTTATCCCAAACACGATCAAAACATTACGAGCTCACAAGTTCAGCCATTTGCCTCAGCCTGATTGGATGCGTTGCAAGTTGTGCTATAGGGGCTATAAGGAGCATCACGAACTGGTCACGCATCTGCTCAAGCATCACCATCTGGAGACTTTAATGCCCGAAGCTGAAGAGACTGAGGAAGCAATGCCTAGTGCTAAAGATGCCGAAGATGATGGCGAGGAAAATgctgacaatgacaatggcaATGGCTGCGATGATGAGTTGTTGCAATGGGACGAAGCACCACGTCGGGGAGGTCGCATAAGTAGTGATGATATGTATGAGCCTCACATTGACTACCTCTGTCCACAGTGTGGCAGGGAGTTCATCGAGAAGAAACACTGGCGAACCCATGTCGTCCAAGTGCATGGAATGAACGATTTGGCCAAACTGAACTTTGAAGTAATCAACGATAGACAATTGAAGTGCACGGAATGTGACAAGATCATAACGAATGCGTATGGTATACAGAATGCCCAACAACATCGGATTACGCATCTGCCGTATAAGGCATATGCACGTTGCCGCAAGTGCCACAAATCGTATACGGATCGCAAGGGTTTGGTCAAGCATTTGGCCACATACCATCGTGTAGGATACGAGCCGCGAAAACATGCTGGTGGATCAGGATTGAGTTCGGGAAATGGAAGCGGAAGTATCTCTGCAAGTGGTCAGTCTTCCAAGTCACAAGCACCACGTAAACAAATTGTCACGGTGGCAAATGAAACATATGAGATTATATACTTGGATGAGGAGCAATCACCGcccagtaacaacaacattaacgaGGAGAACGATTTTGGTGAACAAATGCAagcagatgatgatgattatgccGTTGGTAGCAGTAGCAATGTTACCAGTAGCACCAGTCGTCAACTGCCACCTGCTGTTGCTCCCAATCCCAATCGCTACAAGTGCGTTGACTGCGGCTCCTTGTTCCCAACACAGGTGGCACTTAAAACGCACATTAGCGAGGAGCATGATTTTATGGATACACAATACAGTGCCAAAAAGTTTGATAACGCCGAACCGACTGAGGAGGCCGCTTCTGCATCAGCTTCAACTCAAGTGCCAGTGGCGAAAACGTCGCCAGCCACAAGTACCAGTAAAAAGACATCACAAACAAATAGCTCTGGTTCATCGACAATAGAGCAAAACTATATATTCCTGTGCCCATCGTGTGGCAAGGCATACAAGACCCAGTTTGAGTGGCGTCGTCATATCAATGATGCCCACAACTTTGACAAGCGTCAGTATTTGAATATGCGGCAGCTGGACAAATATCGATACCAGTGTACTCAGTGCAAGGATGTTGTGAGCAGTTCTAAGCTTAAGGGTCTACAGGATCATCACTTCCGTCATCTGCCCTATCGACTGTATTTAAAGTGTCTCGTCTGCGGCACATGCTACAATCACAAGCCCAACATTGCGGCACATCTGCGTACGCGCCACAATATCTATGAAAGGGATACGCCTTGGCGTGAGCAGCAGCCTAAGCCACAGTACAACTATGTGATTCAGAAAGACAAGGATAAAGAAAGGGAATCTCGTGGCATATCCTCTCCATCAACATCGCCGACACCCGGCAGCAGTAGCGTTTATGTAGGACGCACCCTAAAACCGCAACCTGGTGTGCTGCCCACTCGACCGGCTGGTCTGAATACGTTAGAGGACAGCATTTCATATCATAATGCTGTAGATCTGGACTTTATCACGTACTATTGTCCCAAGTGCAACAAGAACTTTGATTCGCATGCCTTCTGGCGCAAACACATCGTGGAACACCATAATTACAATAGTCGCCAGGGTCTCAACTTTCGTCAGATCGATATGCATCACTATTTGTGCCTCGAGTGCTATAAGCGTGTAACTGTCACCCATACGAAGGGTGCCATAGGCCAACTGCAATCGCACAAGTTCCGACATTTGCCCTATCGCTCATTTAAATGCTTGACCTGCAATGGAGAATTTGTGCGGAAGCAAATGTTCTTTAAGCACTTGAATCGCGACACAAATCGTTGTGACAACAAACCTCTCAGTGCCCAGGATAACGACGATGATGTTGGGAATCAGCATGTGACAATTGCTTCTGTTCCTGCTGTTGAGGATATTGATCCCGGTGCGTATTGCTTTTGGTGTCCCCAATGTGGCGATAACTTTACAACCAGTAGCAAAGCGCTTTGGCGTGAACACATTAACATGCATCATGGTCTGGGCAAGCGGGATCATCTCCATATGCGAAAACTGGGAGAGGAACTGTATGGCTGCACGGATTGCGACGAACAGTTGCAAACGAAGCAACTGCGAGTGCTGCAAGAACATCGCTTCAGACATTTACCCTTTGCTGCCTATATACGCTGCCAGCTATGCGAGCATCAGCAGGATGAACTGGGTCATGGAGCTGTCGCAGCTGGTCTGCACAGTATGCAAGAGTTGCAGCAACACATACGCGACAAGCATCCCGATGTGCCCGACAATGATGGACAAatacaatcaatagtgaacgatGAGGGCAGCCAGCCGGCAAATAATGAGTCGTCTGGGAATGGAAGATATATGCCACTTCCACCGCATTTGCTGGACGATGATGTCGATGACGTGGAATTTGAGGAACAGTATCTGCTGGGTTAA
Protein Sequence: MEGMDLWTSMFSTDFEEGDGDGEGDSYNNNAQADVFMGEEEGEEEDQEGDIDEIDDDGEGDDSRRRQGKRKRHEPDDDAIFDFELEPIVNIAEPQPERRGTVALAPPMPSGPPVRGMHHRQSLPASFGSALMPRGTGAGTAPTRPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRKGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGDGTAGRKTRVREPRTEQHLTLQPPPIHDDDDCLEVRNEQVETDGPAGTEANIGLDDDPSSLAKRKRSNPGTGNGNGNSAADMCEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKTLRAHKFSHLPQPDWMRCKLCYRGYKEHHELVTHLLKHHHLETLMPEAEETEEAMPSAKDAEDDGEENADNDNGNGCDDELLQWDEAPRRGGRISSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKHAGGSGLSSGNGSGSISASGQSSKSQAPRKQIVTVANETYEIIYLDEEQSPPSNNNINEENDFGEQMQADDDDYAVGSSSNVTSSTSRQLPPAVAPNPNRYKCVDCGSLFPTQVALKTHISEEHDFMDTQYSAKKFDNAEPTEEAASASASTQVPVAKTSPATSTSKKTSQTNSSGSSTIEQNYIFLCPSCGKAYKTQFEWRRHINDAHNFDKRQYLNMRQLDKYRYQCTQCKDVVSSSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERDTPWREQQPKPQYNYVIQKDKDKERESRGISSPSTSPTPGSSSVYVGRTLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEHHNYNSRQGLNFRQIDMHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPLSAQDNDDDVGNQHVTIASVPAVEDIDPGAYCFWCPQCGDNFTTSSKALWREHINMHHGLGKRDHLHMRKLGEELYGCTDCDEQLQTKQLRVLQEHRFRHLPFAAYIRCQLCEHQQDELGHGAVAAGLHSMQELQQHIRDKHPDVPDNDGQIQSIVNDEGSQPANNESSGNGRYMPLPPHLLDDDVDDVEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00602113;
90% Identity: iTF_00608726;
80% Identity: -