Basic Information

Insect: Drosophila testacea
Gene Symbol: -
Assembly: GCA_035043265.1
Location: JAWNND010000558.1:3329939-3334401[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00046 0.035 14.8 0.1 1 23 168 191 168 191 0.96

2 14 0.0016 0.12 13.1 2.9 2 23 240 262 236 262 0.89

3 14 0.014 1 10.1 0.9 1 23 362 385 362 385 0.93

4 14 0.71 54 4.8 6.1 2 23 434 455 433 456 0.95

5 14 0.0036 0.27 12.0 0.5 1 23 524 547 524 547 0.88

6 14 2.2 1.7e+02 3.2 0.1 2 14 566 578 565 590 0.85

7 14 0.00076 0.058 14.1 3.3 2 23 598 620 598 620 0.96

8 14 0.0016 0.12 13.1 0.1 1 23 729 752 729 752 0.95

9 14 0.00012 0.0091 16.6 0.2 1 23 814 837 814 837 0.92

10 14 0.0013 0.098 13.4 2.2 2 23 887 909 886 909 0.97

11 14 0.0036 0.28 12.0 3.8 1 23 998 1020 998 1021 0.94

12 14 0.058 4.4 8.2 1.5 1 21 1073 1093 1073 1094 0.95

13 14 0.54 41 5.1 0.6 3 23 1138 1160 1136 1161 0.88

14 14 3.4 2.6e+02 2.6 1.2 1 14 1179 1194 1179 1203 0.62

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00046	0.035	14.8	0.1	1	23	168	191	168	191	0.96
2	14	0.0016	0.12	13.1	2.9	2	23	240	262	236	262	0.89
3	14	0.014	1	10.1	0.9	1	23	362	385	362	385	0.93
4	14	0.71	54	4.8	6.1	2	23	434	455	433	456	0.95
5	14	0.0036	0.27	12.0	0.5	1	23	524	547	524	547	0.88
6	14	2.2	1.7e+02	3.2	0.1	2	14	566	578	565	590	0.85
7	14	0.00076	0.058	14.1	3.3	2	23	598	620	598	620	0.96
8	14	0.0016	0.12	13.1	0.1	1	23	729	752	729	752	0.95
9	14	0.00012	0.0091	16.6	0.2	1	23	814	837	814	837	0.92
10	14	0.0013	0.098	13.4	2.2	2	23	887	909	886	909	0.97
11	14	0.0036	0.28	12.0	3.8	1	23	998	1020	998	1021	0.94
12	14	0.058	4.4	8.2	1.5	1	21	1073	1093	1073	1094	0.95
13	14	0.54	41	5.1	0.6	3	23	1138	1160	1136	1161	0.88
14	14	3.4	2.6e+02	2.6	1.2	1	14	1179	1194	1179	1203	0.62

Sequence Information

Coding Sequence: ATGGAAGGTATGGACTTATGGACGTCCATGTTTTCGACCGACTTTGAGGAGGGCGACGGTGACGGTGAGGGGgatagctacaacaacaacgcgcAGGCAGACGAGTTTATGGGTGAAGAGGAGGGTGATGAGGAGGACCAGGAGGGTGATATAGACGAgattgatgatgatggggaGGGTGATGATAGTAGACGTCGTCAGGGGAAGCGAAAGAGACATGAGCCTGATGATGATGCCATATTTGATTTCGAATTGGAGCCTATTGTTAATATTGCTGAGCCACAACCAGAACGGAGAGGAACTGTCGCATTGGCGCCCCCAATGCCATCTGGACCACCTGTAAGGGGAATGCATCACCGTCAATCATTGCCAGCATCGTTTGGATCAGCATTAATACCACGAGGAACTGGTGCAGGAACAGCTCCAACACGACCAACGACTTCACAAATCAATGCCACCGATGAGAATGGTGTTCCAATTAATTACGAATTGGGAGTTATTTACATATGTCCTGCATGCGGAGCCGAATATCGACAGCAGGATATGTGGAAGCGTCACATGAACCAAATGCATCAGTATAATACACGCAAAGGACTCAATTTTGTGGCGATCGATAAGCTGTATCATCGGTGCCTAGAGTGCAACAAGCGGATTGCGATGCATAGTCGAGAGAATCTTCTCAAGCATAAGTTTACCCATTTGCCATATCGGTGCACCAAGTGCTATATATGTAAGCGAGAGTACAAATACAGGCAGGACCTGATGGTGCATCTGCGTATGGTGCACTGTGATGAAGTAGTTGCCATGATGCGGGAAGGCGACGGCACAGCTGGAAGAAAGACGCGTGTCCGTGAACCACGTACCGAGCAACATCTAACTCTTCAACCTCCCCCAATCCATGACGATGACGATTGCCTAGAAGTGAGGAATGAACAAGTTGAAACAGATGGTCCTGCAGGCACTGAGGCCAACATCGGTCTGGATGACGATCCAAACTCATTAGCAAAACGGAAACGTAGTAATCCAGGTACAggcaatggaaatggcaatAGTGCTGCAGACATGTGTGAGGATTACATACACTACATGTGCCCGGATTGCGGCACAGACTGTGACACTCATGCCCAGTGGAGTCAACACATTGAATTCGTACACGATTATGTGAGTAGGCGAGGTCTCAACTTTCGATGCGTCGATATGCAGATGCAGTGCCTGGAGTGCAAACAGTTTGTTATCCCAAACACGATCAAAACATTGCGAGCTCACAAGTTCAGTCATTTGCCTCAGCCTGATTGGATGCGCTGCAAGTTGTGCTATAGGGGCTATAAGGAGCATCACGAACTGGTCACGCATCTACTCAAGCATCACCATCTGGAGACTTTAATGCCCGAAGCTGAAGAGACTGAGGAAGCAATGCCCAGTGCTACTACCGAAGATGATGGCGAGGAAAATgctgacaatgacaatggcaatggcaatggctgCGATGATGAGTTGTTGCAATGGGACGAAGCACCACGTCGAGGAGGTCGCATAAGTAGTGATGATATGTATGAGCCTCACATTGACTACCTGTGTCCGCAGTGTGGCAGGGAGTTCATCGAGAAGAAACACTGGCGAACCCATGTCGTCCAAGTGCATGGAATGAACGATTTGGCCAAACTGAACTTTGAAGTAATCAACGATAGACAATTGAAGTGCACTGAATGTGACAAGATCATTACGAATGCGTATGGTATACAGAATGCACAACAACATCGGATTACGCATCTGCCGTATAAGGCATATGCACGTTGCCGCAAGTGCCACAAATCGTATACGGATCGCAAGGGTTTGGTCAAGCATTTGGCCACATACCATCGTGTGGGATACGAGCCGCGTAAACATGCGGGTGGATCAGGATTAAGTTCGGGAAGTGGAAGCGGAAGTATTTCTGCAAGTGGTCAGTCTTCCAAGTCACAACTACCACGTAAACAAATTGTCACGGTGGCAAATGAAACATATGAGATTATATATTTGGATGAGGAGCAATCACCgcccagtaacaacaacattaacgaGGAGAACGATTTTGGTGAACAAATGCAagcagatgatgatgattatgccGTTGGTAGCAGTAGCAATGTCACCAGTAGCACCAGTCGCCAATTGCCACCTGCTGTTGCTCCCAATCCCAATCGCTACAAGTGCGTTGACTGCGGCTCCTTGTTCCCAACACAGGTGGCACTTAAGACGCATATTAGCGAGGAGCATGATTTTATGGATACACAATACAGTGCCAAAAAGTTTGATAATGCCGAACCGACTGAGGAGGCAGCTTCTGCATCAGCTTCAACTCAAGTGCCAGTGGCAAAAACGTCACCAGCCACAAGTAGCAGTAAAAAGACATCACAAACAAATAGCTCTGGTTCATCGACAATAGAGCAAAACTATATATTCCTGTGCCCATCGTGTGGCAAGGCATACAAGACTCAGTTCGAGTGGCGTCGTCATATCAATGATGCCCACAACTTTGACAAGCGtcagtatttaaatatgcgGCAGCTGGACAAATATCGATACCAGTGTACTCAGTGCAAGGATGTTGTGAGCAGTTCGAAGCTAAAGGGTTTGCAGGATCATCATTTTCGTCATCTGCCCTATCGACTGTATTTAAAGTGTCTCGTCTGCGGCACATGCTACAATCACAAGCCCAACATTGCGGCACATCTGCGTACGCGCCACAATATCTATGAAAGGGATACGCCTTGGCGTGAGCAGCAGCCTAAGCCACAGTACAACTATGTGATTCAGAAAGACAAGGATAAAGAAAGGGAATCTCGTGGCATATCCtccccatcatcatcaccGACACCCGGCAGCAGTAGCATTAATGTAGGACGCACCCTAAAACCACAACCAGGTGTGCTACCCACTCGACCGGCTGGACTGAATACGTTGGAGGACAGCATTTCATATCATAATGCTGTAGATCTGGACTTTATCACGTACTATTGTCCCAAGTGCAACAAGAACTTTGATTCGCATGCCTTCTGGCGCAAACACATCGTGGAACACCATAATTACAATAGTCGCCAGGGTCTCAACTTTCGTCAGATCGATATGCATCACTATTTGTGCCTCGAGTGCTATAAGCGTGTAACTGTCACCCATACCAAGGGTGCCATAGGCCAACTGCAGTCGCACAAGTTCCGGCATTTGCCCTACCGCTCATTTAAATGCTTGACCTGCAATGGAGAATTTGTGCGGAAGCAAATGTTCTTTAAGCACTTGAATCGCGACACAAATCGTTGTGACAACAAACCGCTCAGTGCCCAGGATAACGACGATGATGTTGGGAATCAGCATGTGACAATTGCTTCTGTTCCTGCTGTTGAGGATATTGATCCCGGTGCTTATTGCTTTTGGTGTCCCCAATGTGGCGATAACTTTACAACCAGCAGCAAAGCGCTTTGGCGTGAACACATTAATATGCATCATGGCCTGGGCAAGCGGGATCATCTCCATATGCGGAAACTGGGAGAGGAACTGTATCGCTGCACGGATTGCGACGAACAGTTGCACACGAAGCAACTGCGAGTGCTGCAAGAACATCGCTTCAGACATTTACCCTATGCTGCCTATATACGCTGCCAGCTGTGCGAGCATCAGCAGGATGAACTGGGTCATGGAGCTGTGGCAGCTGGTCTGCACAGTATGCAAGAGTTGCAGCAACACATACGCGACAAGCATCCCGATGTGCCCGACAATGATGGACAAATACAATCACTAGTGAACGATGAGGGTGGCCAGCCGGCAAACAATGAGTCGTCTGGGAATGGAAGATACATGCCACTTCCACCGCATTTGCTGGACGATGATGTCGATGACGTGGAGTTTGAGGAACAGTATCTGCTGGGTTGA
Protein Sequence: MEGMDLWTSMFSTDFEEGDGDGEGDSYNNNAQADEFMGEEEGDEEDQEGDIDEIDDDGEGDDSRRRQGKRKRHEPDDDAIFDFELEPIVNIAEPQPERRGTVALAPPMPSGPPVRGMHHRQSLPASFGSALIPRGTGAGTAPTRPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRKGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGDGTAGRKTRVREPRTEQHLTLQPPPIHDDDDCLEVRNEQVETDGPAGTEANIGLDDDPNSLAKRKRSNPGTGNGNGNSAADMCEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKTLRAHKFSHLPQPDWMRCKLCYRGYKEHHELVTHLLKHHHLETLMPEAEETEEAMPSATTEDDGEENADNDNGNGNGCDDELLQWDEAPRRGGRISSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKHAGGSGLSSGSGSGSISASGQSSKSQLPRKQIVTVANETYEIIYLDEEQSPPSNNNINEENDFGEQMQADDDDYAVGSSSNVTSSTSRQLPPAVAPNPNRYKCVDCGSLFPTQVALKTHISEEHDFMDTQYSAKKFDNAEPTEEAASASASTQVPVAKTSPATSSSKKTSQTNSSGSSTIEQNYIFLCPSCGKAYKTQFEWRRHINDAHNFDKRQYLNMRQLDKYRYQCTQCKDVVSSSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERDTPWREQQPKPQYNYVIQKDKDKERESRGISSPSSSPTPGSSSINVGRTLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEHHNYNSRQGLNFRQIDMHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPLSAQDNDDDVGNQHVTIASVPAVEDIDPGAYCFWCPQCGDNFTTSSKALWREHINMHHGLGKRDHLHMRKLGEELYRCTDCDEQLHTKQLRVLQEHRFRHLPYAAYIRCQLCEHQQDELGHGAVAAGLHSMQELQQHIRDKHPDVPDNDGQIQSLVNDEGGQPANNESSGNGRYMPLPPHLLDDDVDDVEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00602113;
90% Identity: iTF_00558213;
80% Identity: -