Cpag007063.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cheilosia pagana
Gene Symbol
Hr39
Assembly
GCA_936435595.1
Location
CAKZFE010000024.1:1549693-1556319[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.2 4.2e+03 -3.0 6.3 54 132 220 300 136 354 0.52
2 3 8.3e-14 1.8e-09 37.8 9.3 1 142 445 593 445 606 0.66
3 3 4.7e-80 1e-75 256.0 0.2 200 408 610 811 596 811 0.96

Sequence Information

Coding Sequence
ATGTCATCATCGATAAAAAGTGAAACGTCCGCATACAGTGCGGGTCACGGCAGCACAATCACTAACATCGTTGGCATTCAGCAGCCATCGACAACATCATCCATCATTCGCAACAATGTCTCTGTGACGAACATTAAATGTGAAGTGGACCGCAATAGCAGTGCCATTCGGTCCATCCATCCATCGGCGCCGCCCATTGTGACAACATCTTACTACAACAAGGGCAACGGCGCCATACGGATTCCCGTGACCAAGGGCGACGAGTCCGACTCGGAGACTGAGCTGTCGCACATCGAAAACCTCAAGGTCACCCGTAGAGCAGTCAGTCAATCGGTGAAGAATGGCCCCCGGCCCATGTCGTGGGAGGGCGAACTCTCCGATCCCGAACCAGACCCAATGGACACGGAGAATTCGACCAGCTGCGACAAGACCTTCTCCTCTCAGCCGGTGACAGTGATCAAGAATGACCCCGATTGCAAGCTTGATCAGATCTGCGTCGAGATAAACTCATCACACTACGTTAACAAGAAGCCACAGAGTGATCCTATTAACCTTAAGTATGAGCCAGGTCTACTGGCCGATCCCACCGGCAGCAGTAACTCGCCATTGCTCGCTCGCTCCAAGACGACGGCCAATCTGTTGCCCGCCAATCCTAGCCCCGATTCTGCCATTCATTCCGCGTACACGCACAGTTCGCCGAGTCAATCGCCGCTAACGTCGCGACACGCCCCCTACACACCGTCGCTGAGTCGCAACAATAGTGATGCGTCGCACAGCAGCTGTTACTCGTACTCGTCGGAGTTCAGTCCGACGCACTCGCCGATTGCAGGCCGACACAACATGTACGGCAGCTACAATGGCGGGTCACTTCATCATTCCGTTTTGTATCGGCCGACAATTATTGACAGCGGCAGCAGTGCTGCCAGCACGTCGTCGTCCGATCCACAGAATCTATCACAAGCCGCTGTAGTAGCAGCGGCGGCATCTGCGCTGGCCGCAGCCGCCTCCACATCAATCTCTGTAAATGGCAGCACCCCGCCGGGACTCAAGACGGAAGAGTTGCTCTTCGACAGCGAGGCCATACCCTCGGCGGGTATATCGCGACAGCAGCTAATCAACTCACCGTGTCCCATATGTGGGGACAAGATCTCCGGTTTCCATTATGGCATCTTTTCGTGCGAGTCGTGTAAGGGCTTCTTCAAGCGGACGGTACAGAACCGCAAGAACTATGTCTGTGTGAGGGGCGGACCCTGCCCAGTGACGATCTCCACGCGGAAAAAGTGTCCGGCGTGTCGCTTCGAGAAGTGCCTTCAGAAGGGCATGAAATTGGAGGCGATACGCGAGGACCGAACCCGTGGTGGGCGATCCACCTACCAGTGCTCCTACCAACTGCCCAATTCCATGCTGAGTCCGCTGCTGAAACACGAGCAATCTggtcagcagcagcagcaacagccgcCGCAGCACAGCTCCCGCATGGGAGTGAATGGTTTTGTTATAAAGACCGAACAACCCGACAGCAGCACGGGTGGCACATCGACTCCAACACCGGGAGGCAGCGGCAGtcatcatcaccaccatcatcatcatcatcaccaacagcaacagcagcagcagcagcgttcGCCGAATAACGAAATCCCCACCTTACTGCAGGAGATCATGAACGTTGAGCATCTGTGGCAGTATAATGCAACCGAGTTGGCACGACTGAATGAACCGTTGTCGTCGTCGATGTGctcgtcgtcatcatcagcgTCGGCATCGACATCGGCCCCGCCTGGTAATATTGCGTCAAATCCGCTGCTGGCCAGCGCCGGTCTCTCAGCCAACGGAGAGAATGCAAATCCAGACTTAATCGCCAACCTGTGCACGGTGGCCGATCATCGGCTGTACAAGATCGTCAAGTGGTGCAAGAGCTTGCCGCTGTTTAAGAATATATCCATTGATGATCAAATTTGCCTGCTGATCAATTCGTGGTGTgaacttttattgttttcatgTTGCTTCCGATCGATCGATACACCAGGCGAGATCAAGATCTCACAGGGGAAGTCCATCAATTTGGCTCGCGCGAAGTCGAATGGTTTGCAGTCGTGCATTGAACGAATGCTGAATCTGACAGACCATTTACGACGATTGCGGGTCGATCGGTATGAATACGTTGCCATGAAAGTGATCGTTCTCCTTCAATCAGATACATCTGAGTTGCAAGAACCCGTCAAAGTTCGTGAGTGTCAGGAGAAAGCCCTACAATCGCTGCAGGCGTACACATTAGCCCACTATCCCGAGATGCCATCGAAATTCGGTGAACTACTGCTAAGGATTCCCGAGCTACAAAGAACGTGTCAGCTTGGCAAAGAGATGCTAACAATCAAATCCCGTGACGGTGGTGACTTCAATTTACTTATGGAGCTCCTCCGCGGAGAGCATTGA
Protein Sequence
MSSSIKSETSAYSAGHGSTITNIVGIQQPSTTSSIIRNNVSVTNIKCEVDRNSSAIRSIHPSAPPIVTTSYYNKGNGAIRIPVTKGDESDSETELSHIENLKVTRRAVSQSVKNGPRPMSWEGELSDPEPDPMDTENSTSCDKTFSSQPVTVIKNDPDCKLDQICVEINSSHYVNKKPQSDPINLKYEPGLLADPTGSSNSPLLARSKTTANLLPANPSPDSAIHSAYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIAGRHNMYGSYNGGSLHHSVLYRPTIIDSGSSAASTSSSDPQNLSQAAVVAAAASALAAAASTSISVNGSTPPGLKTEELLFDSEAIPSAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCPVTISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYQLPNSMLSPLLKHEQSGQQQQQQPPQHSSRMGVNGFVIKTEQPDSSTGGTSTPTPGGSGSHHHHHHHHHHQQQQQQQQRSPNNEIPTLLQEIMNVEHLWQYNATELARLNEPLSSSMCSSSSSASASTSAPPGNIASNPLLASAGLSANGENANPDLIANLCTVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKISQGKSINLARAKSNGLQSCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTSELQEPVKVRECQEKALQSLQAYTLAHYPEMPSKFGELLLRIPELQRTCQLGKEMLTIKSRDGGDFNLLMELLRGEH