Basic Information

Insect: Cheilosia variabilis
Gene Symbol: Hr39
Assembly: GCA_951230905.1
Location: OX579679.1:47377703-47388376[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.34 5.5e+03 -2.8 5.4 54 132 220 301 144 354 0.54

2 3 2.3e-15 3.8e-11 43.9 10.5 1 146 446 596 446 610 0.69

3 3 2.1e-79 3.4e-75 254.9 0.1 200 408 613 815 600 815 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.34	5.5e+03	-2.8	5.4	54	132	220	301	144	354	0.54
2	3	2.3e-15	3.8e-11	43.9	10.5	1	146	446	596	446	610	0.69
3	3	2.1e-79	3.4e-75	254.9	0.1	200	408	613	815	600	815	0.95

Sequence Information

Coding Sequence: ATGTCATCATCAATAAAAAGTGAACCATCCGCATACAGTGCGGGTCACGGCAGCACAATCACTAACATCGTTGGCGTTCAACAGCCATCGACAACATCATCATCCATCATTCGCAACAATGTCTCTGTGACGAACATTAAATGTGAAGTGGACCGCAATAGCAGTGCTATTCGTTCCATCCATCCATCGGCGCCCATCGTGACAACATCTTACTACAACAAGGGCAACGGGGCAATACGGATTCCGGTGACCAAGGGCGATGAGTCCGACTCGGAGACTGAGCTGTCGCACATCGAAAACCTTAAGGTCACCCGACGAGCAGTTAGTCAATCAGTGAAGAATGGCCCGCGGCCAATGTCGTGGGAGGGCGAACTCTCCGACCCCGAACCGGACCCCATGGACACGGAGAATTCGACAAGCTGCGACAAGACTTTCTCCTCTGCGCCCGTGACAGTGATCAAGAACGACCCCGATTGCAAGCTCGATCAGATCTGCGTCGAGATAAACTCATCACACTACGTAAACAAGAAGCCACAGAGTGATCCTATTAACCTTAAGTATGAGCCAGGCCTCCTGGCCGATCCCACCGGCAGCAGTAACTCGCCGTTGCTCGCCCGCTCCAAGACGACAGCCAATCTGTTGCCCGCCAATCCTAGCCCCGATTCTGCCATTCATTCCGCGTACACGCACAGTTCGCCGAGTCAATCGCCGCTAACGTCGCGTCACGCCCCCTACACCCCGTCGCTGAGTCGCAACAACAGTGATGCGTCGCACAGCAGCTGTTACTCGTACAGTTCGGAGTTCAGTCCGACGCACTCGCCCATTGCAGGCCGACACAACATGTACGGCGGCAGCTACAATGGCGGGTCACTTCATCATTCCGTTTTGTATCGGCCGACAATTATCGACAGCGGTAGCAGTGCTGCCAGCACGTCGTCGTCGGATCCACAGAATCTATCACAAGCCGCTGTAGTAGCAGCGGCGGCATCTGCGCTGGCCGCAGCCGCCTCCACATCAATCTCCGTGAATGGCAGCACCCCGCCGGGACTCAAGACAGAAGAGTTGCTCTTCGACAGTGAGGCCATCCCCTCGGCGGGTATTTCACGACAGCAACTAATCAACTCACCGTGTCCCATATGTGGTGACAAGATCTCCGGTTTCCATTATGGCATCTTCTCGTGCGAGTCGTGTAAGGGCTTCTTCAAGAGGACGGTACAGAACCGCAAGAACTACGTCTGTGTAAGGGGCGGACCCTGTCCAGTGACGATCTCCACCCGGAAAAAGTGTCCGGCGTGTCGCTTCGAGAAGTGCCTTCAGAAGGGCATGAAATTGGAGGCGATTCGTGAGGACAGGACACGCGGAGGGCGGTCCACCTACCAGTGCTCCTACCAACTGCCCAATTCCATGCTGAGCCCACTGCTGAACAATGAACAATGTggtcagcagcagcagcagcaacagcaacagcagcagcacagcTCTCGCATGGGAGTGAATGGTTTCGTAATTAAGACAGAACAGCCCGACAGCAGCACGGGTGGCACATCGACTCCAACACCGGGAAGCAGCGGCAGtcatcatcaccaccatcatcatcatcaccatcaacagcagcagcagcagcagcagcgttCGCCGAGTCACGAAATCCCCACCTTACTGCAGGAGATCATGAACGTTGAGCATCTGTGGCAGTATAATGCAACCGAGTTGGCACGACTGAATCAaccgttgtcgtcgtcgtcctgttcatcgtcatcgtcaacGTCGGCACCGACATCGGCCCCGCCTGGTAATATTGCGTCAAATCCGCTGCTGGCCAGCGCTGGTCTCTCGGCGAACGGAGAGAATGCAAATCCAGACTTAATCGCCAACCTGTGCACGGTGGCCGATCATCGGCTGTACAAGATCGTCAAGTGGTGCAAGAGCTTGCCGCTGTTTAAGAACATATCCATTGATGATCAAATTTGCCTGCTGATCAATTCGTGGTGTGAACTTTTATTGTTTTCCTGTTGCTTCCGATCTATCGACACACCGGGGGAGATCAAGATCTCACAGGGGAAGTCAATCAATTTGGCTCGGGCGAAGTCGAATGGTTTGCAGTCCTGCATTGAACGAATGCTGAATCTGACAGACCATTTACGACGATTGCGAGTCGATCGGTATGAATACGTTGCCATGAAAGTGATCGTTCTCCTTCAATCAGATACATCTGAGTTGCAAGAACCGGTCAAAGTTCGTGAGTGTCAGGAGAAAGCCCTACAATCGCTGCAAGCGTACACATTAGCCCACTATCCCGAGATGCCATCGAAATTCGGTGAACTACTTCTAAGGATTCCCGAGCTACAAAGAACGTGTCAGCTCGGCAAAGAGATGCTAACAATCAAATCCCGTGACGGTGGTGGTGACTTCAATTTACTTATGGAGCTCCTCCGCGGAGAGCATTGA
Protein Sequence: MSSSIKSEPSAYSAGHGSTITNIVGVQQPSTTSSSIIRNNVSVTNIKCEVDRNSSAIRSIHPSAPIVTTSYYNKGNGAIRIPVTKGDESDSETELSHIENLKVTRRAVSQSVKNGPRPMSWEGELSDPEPDPMDTENSTSCDKTFSSAPVTVIKNDPDCKLDQICVEINSSHYVNKKPQSDPINLKYEPGLLADPTGSSNSPLLARSKTTANLLPANPSPDSAIHSAYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIAGRHNMYGGSYNGGSLHHSVLYRPTIIDSGSSAASTSSSDPQNLSQAAVVAAAASALAAAASTSISVNGSTPPGLKTEELLFDSEAIPSAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCPVTISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYQLPNSMLSPLLNNEQCGQQQQQQQQQQQHSSRMGVNGFVIKTEQPDSSTGGTSTPTPGSSGSHHHHHHHHHHQQQQQQQQRSPSHEIPTLLQEIMNVEHLWQYNATELARLNQPLSSSSCSSSSSTSAPTSAPPGNIASNPLLASAGLSANGENANPDLIANLCTVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKISQGKSINLARAKSNGLQSCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTSELQEPVKVRECQEKALQSLQAYTLAHYPEMPSKFGELLLRIPELQRTCQLGKEMLTIKSRDGGGDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00311850;
90% Identity: iTF_01223496;
80% Identity: iTF_00315248;