Basic Information

Insect: Eristalinus aeneus
Gene Symbol: Hr39
Assembly: GCA_955652365.1
Location: OY019133.1:61703153-61706793[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.11 3.1e+03 -2.1 4.0 55 116 223 265 137 356 0.54

2 3 2.1e-16 6.2e-12 46.3 1.5 1 155 447 590 447 600 0.68

3 3 3.3e-80 9.7e-76 256.5 0.3 200 408 594 795 583 795 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.11	3.1e+03	-2.1	4.0	55	116	223	265	137	356	0.54
2	3	2.1e-16	6.2e-12	46.3	1.5	1	155	447	590	447	600	0.68
3	3	3.3e-80	9.7e-76	256.5	0.3	200	408	594	795	583	795	0.96

Sequence Information

Coding Sequence: ATGTCATCATCAATAAAAAGCGATTCATCTGCATTTACTGCGGCAACTCACGGCAGCACAATCACTAACATCATCGGCGTCCAACAACCATTAACGACATCATCTATTATACGCAACAATGTTTCGGTGACCAACATTAAATGCGAGGAGGATCGAAACAGCAGCGCCATCCGGACATCAATATCATCGGCACCAATTGTCACGACATCGTACACATTCAAAGGGAACGGAGCAATTCGAATCCCGGTCACCAAGAGAGACGAGTCTGACTCCGAGAGTGAATTGTCACACATAGAGAACCTTAAAGTAACGCGAAGAGCGGTTAGTCAATCTGTGAAGAATGGCCCACGGCCAATGTCATGGGAGGGTGAGCTCTCTGACACAGAGCCTGATCCTATGGATACAGAGAACTCAGTGAGCTGCGACAAGACTTTTTCAAATGAACCCGTGACGGTGGTCAAGCACGACCTAGACAGAAAGACAATTCTTGACCAGATCTGTGTAGAGATAAACTCATCTCACTACGTAAATAAGAAGCCACAGAGTGATCCTATTAACCTTAAGTATGAGCCGGGTCTCCTGGCAGATCCCACCGGCAGCAGTAACTCGCCGTTGCTTGCGCGCTCGAAGACAACAGCTAACTTGCTGCCTGCCAATCCTAGCCCCGATTCTGCCATTCATTCCGCGTATACGCACAGCTCACCAAGTCAATCGCCGCTTACGTCTAGACACGCTCCCTACACACCGTCGTTGAGTCGAAACAATAGTGATGCGTCGCACAGCAGCTGCTATTCCTACAGCTCGGAGTTTAGCCCAACACACTCGCCTATTGCTGGCCGACATAACATGTACGGCAGCTACAATGGCGGCTCTCTTCATCATTCCGTATTGTATCGTCCGGCGATAGTTGACAATGGCAGCAGCGCTACCAGTGGCTCCTCGTCTGACCCACAGAATTTATCACAAGCCGCTGTAGTTGCAGCGGCAGCATCTGCGCTGGCCGCAGCCGCATCCACATCAATCTCTGTAAACTGCAGCACTCCAACTGGGCTTAAAACCGAAGAGCTTCTCTTCGACAGTGAGGCAATCCCATCAGCAGGTATTTCACGACAGCAACTAATCAACTCTCCATGTCCCATTTGCGGGGACAAGATCTCTGGATTCCATTACGGTATATTCTCCTGTGAGTCGTGCAAGGGTTTTTTCAAGAGAACAGTGCAGAATCGCAAGAACTACGTCTGCGTTAGGGGTGGACCATGCCCAGTAACAATATCGACCCGTAAAAAGTGTCCCGCGTGtcgcttcgaaaagtgcctacAAAAGGGAATGAAACTCGAAGCCATTCGCGAGGACCGAACACGTGGTGGCCGATCTACATACCAATGTTCGTACACGCTGCCTAATTCAATGTTGAGTCCCTTAAAGATTGAATCCTCAagccagcagcaacaacagcaacagcatagCTCCCGCATGGGAGTTAACGGCTTCATCATAAAAACCGAACAACCTGACAGTAGTACGGGAGGTACTTCCACGCCAACACCAGGCAGCAGCGGCAACGGAAGCAGTAACAGTCATCAACGTCCCGCGAATCACGATATTCCCACCCTGTTGCAGGAGATAATGAATGTTGAACACTTATGGCAGTACAATGCAGGCGAATTAGCACGACTGAATCAACCATTGTCAGCGTCATGTTCGTCATCCTCTGCATCCGCTTCTACATCAGCTGGTAATATCTCGTCCAATCCGCTGCTGGCCAGCGCTGGTCTCTCTTCGAACGGGGAGAATGCAAATCCAGACCTGATCGCCAACTTGTGCACTGTGGCTGACCACCGGTTGTATAAGATCGTAAAGTGGTGCAAGAGTTTGCCGTTATTTAAGAATATATCCATTGATGATCAGATCTGTCTCTTGATTAACTCGTGGTGTGAGCTTTTATTGTTTTCGTGTTGTTTTCGGTCTATAGACACACCAGGTGAGATTAAAATCTCACAAGGAAAGTCAATAAATCTGACACGGGCTAAGTCAAATGGTTTGCAGTCCTGCATTGAACGAATGCTTAATCTGACAGACCATTTACGACGCTTGCGAGTCGATCGGTATGAGTATGTTGCCATGAAAGTCATTGTTCTACTCCAATCAGACACATCTGAGTTGCAAGAACCCGTTAAAGTTCGTGAGTGTCAAGAGAAAGCTCTACAATCGCTGCAGGAATACACGTTAGCTCACTACCCAGAAATGCCATCAAAGTTCGGTGAACTACTACTGAGAATACCAGAGCTGCAGAGAACGTGTCAGCTTGGCAAAGAGATGCTGACGATCAAATCCCGCGACGGCGGTGATTTCAACTTACTTATGGAACTTCTGCGTGGAGAGCATTGA
Protein Sequence: MSSSIKSDSSAFTAATHGSTITNIIGVQQPLTTSSIIRNNVSVTNIKCEEDRNSSAIRTSISSAPIVTTSYTFKGNGAIRIPVTKRDESDSESELSHIENLKVTRRAVSQSVKNGPRPMSWEGELSDTEPDPMDTENSVSCDKTFSNEPVTVVKHDLDRKTILDQICVEINSSHYVNKKPQSDPINLKYEPGLLADPTGSSNSPLLARSKTTANLLPANPSPDSAIHSAYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIAGRHNMYGSYNGGSLHHSVLYRPAIVDNGSSATSGSSSDPQNLSQAAVVAAAASALAAAASTSISVNCSTPTGLKTEELLFDSEAIPSAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCPVTISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLKIESSSQQQQQQQHSSRMGVNGFIIKTEQPDSSTGGTSTPTPGSSGNGSSNSHQRPANHDIPTLLQEIMNVEHLWQYNAGELARLNQPLSASCSSSSASASTSAGNISSNPLLASAGLSSNGENANPDLIANLCTVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKISQGKSINLTRAKSNGLQSCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTSELQEPVKVRECQEKALQSLQEYTLAHYPEMPSKFGELLLRIPELQRTCQLGKEMLTIKSRDGGDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00311850;
90% Identity: iTF_01223496;
80% Identity: iTF_00671002;