Math036818.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Mellicta athalia
Gene Symbol
RREB1
Assembly
GCA_905220545.1
Location
HG992201.1:7331127-7337715[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.5 62 5.7 0.8 1 23 113 136 113 136 0.94
2 12 1.5 1.9e+02 4.1 0.3 1 12 168 179 168 189 0.82
3 12 0.024 2.9 9.9 0.1 1 23 316 338 316 338 0.97
4 12 0.0013 0.16 13.8 0.4 1 23 347 369 347 369 0.99
5 12 0.00079 0.097 14.5 2.0 1 23 375 398 375 398 0.97
6 12 0.0032 0.39 12.6 1.6 1 23 747 770 747 770 0.96
7 12 0.00027 0.033 16.0 1.3 2 23 961 982 960 982 0.97
8 12 0.027 3.3 9.7 5.3 1 23 988 1011 988 1011 0.97
9 12 0.22 27 6.8 0.8 1 23 1041 1065 1041 1065 0.90
10 12 0.06 7.4 8.6 0.5 1 23 1087 1110 1087 1110 0.94
11 12 0.024 3 9.8 0.3 2 23 1150 1171 1149 1171 0.92
12 12 0.03 3.7 9.5 5.3 1 23 1177 1199 1177 1199 0.97

Sequence Information

Coding Sequence
ATGACAGTATTGATTTTCCTCCGACCAACCAGAGGCCGACGAAAACACCTCGCACTAACGCGATCAAATAAACATAGCCACCGCGCTGAGAAACTGTTCGTTTTTGTGTCTATAcgtatacaagAGATCAAAACTGAAGTTATCAGCGAGGCCAAAATCGAAACGGATAATCAAGCAATGAAAATTGAGGAACAGGAAACACGCGCGACGCGCACCACCAGCATCGACAGTGATAACCGTTCAGACAGAAGTGAAGAGGAGGAATGCAGGCGAGCTCGGAAGAGAGCCGCGTCTACATCAGCATCACCTATACCACTGGACAAGAGAACAGCTCGTTTTGAGTGCCCCAAGTGTTTACAGCGATTTGATTCAATAAACACCTTCGATCTTCATCGTTTCACGGCGCACGGGGACGACACCAGATCCGGGTATGACGACTACATAGACTACTCTGGGAAGAAATTCgcagatattttaaaaaacccTCACGCTGAGCAGCGCTTTCGATGCGAACATTGCTCCCGAGATTTTCCATCCGGACAAATCTTAGACGTCCATAGAAAAACGTGTGCGTTATCTACAAGGATCTCTAGTCCTGATCATGACCGCAGAGAAGATTTTTTCGCTAAATTGGATCTTAGAAATAGATCTTTTGGTATACCAGGTACATTGACCCCTCCGATGGATCGCTTTCCATCTAAATTTGAAGACGGACATCTGACTAATGGAATTAGGCATATAGATGCCGCGAGAGACTTAGCTGATATTCAATCCATTCTAAACGTTACGTCTGCTGGAAGTCTCTTAGAAAGACTGACAGGAACGAGAGTTGCCTTGGAAAATGCTGTCTTAACACCTCCCGATACTATTACCAAAGAAAGGGAGACAGAGGAGACACAGGACAATTTTGCAGCGGAATTCAGACGAATGAAGCTACGTGGTGAATTCCCGTGTAGACTGTGTCCCGCAAAATTTCCGAACCTGCGTGCATTGAAAGGTCACAATAGAGTACATCTAAGTGGAACCGGTCCTGGCCCCTACCAGTGCAATATGTGTCCTCATGCATCTTTAGACAAGGCAGCACTAGTTCGGCACATGCGCACTCATAATGGTGACAGACCTTATGAGTGTGCTGTATGTAATTACGCTTTTACTACGAAGGCTAATTGTGAACGACATTTGCGTAATCGTCATGCTAAGGTGACGAGAGAAGATGTCAAGCGCTCAATAATATATCATCCGTCAGAAGATCCTAATAATGATGAGGTTAACTCTAAACTGACTCGTGATGAAGTTAAGAGATCGCTTGCATTCCACACACCGGAATCAGAAAAACTCAGAGAACCCACGGACCGCAGCACACCGTTGACCCACTACAATCCTAGCTTCATACCCGATAGACATCCTGTAACTTCACTTAATAAATCTCTGCCTGATTCACCCGCATTAACTCCCAGAGAGTCAGAACTGCCATTGCCTAGAATAAAAGTTAAAGGTATCGGACAACTCACTCAAATACCAGAGTTTAGAACTCCGGACATATCTTTCAAAGTCGATGTACAACCGGAAACTTATAATGAAGATACTCCAGTTGATCTTAGAACAAGTGACAATAATAGTTGTGATGTATTAGATCTCAGTAAGAAAAAGAGAGACACAGATAACGATGAGCCTAAGGCCACATCGCAACCAGCTTTTAATAGTTCCACATCAGTTGCAGCGACAGCAGCAGCAGCGGCGGCGTTTGAAGAAACAAGATTTATTCTAGCACAGCAAAGGCTGTTAGAAAGTTCTTTCCCAAAAATGGACTCGGCACTTTATGTTAATCAGTTATCACAACTCTATGCCAGCGCAGTACCCGGTTTGCCTGGTCTACCTCTACCACCCTCGTTTCCGATAAACCCTTATATCCTCCAACCTTCCTTTTTTCCACACCCATCTGACTCGCCAGAGATAGCGGAAATAAAATCACGAATACAGAAAGAAATCATTCGAGGTCTTAGCATGTCCGGTGGTAGATTGGTTAACACCGAAACTGAAAATCAGCTAAAAAAAGAACCTGAAGAAGAGGAACAAAAGCCAATTCAGGTTTCCACGACGCCAACCCCGCCTCCCCACTCAGAATCTCCGCTACCAATAACTAACGTTATTTCTCAAAACGATTCCGTGAAAATGGTAATAAAGAACGGTATTCTTATGCCAAAACAGAAACAAAGGCGTTACAGAACCGAGCGTCCGTTTTCCTGCTCCCAGTGTTCCGCTCGCTTTACATTGCGATCAAACATGGAACGACACGTAAAACAACAGCACCCCCATCACTGGAGTGTCAGACGTCCAGCGACGAGAGCGCCTCCACCATACCCAACTAACGACACACTAGCTGATCGTGTCAAATACGCGTTGCTGGCTCGTCAGTTGGAAAGACCCATCACTTCTGATCGTTCCCCTGTCAGGAGAGATTCGGATGAAGTTGCTGACAATGAGGAAGACGAAGACGATACGTTAGTTATCGATGAGGAACCAGAGGACCAGAAAGCAGATGAACGTTCAGCCGCACATCGAGCAGCAGCGGAAATCCTTATGGCTACACGTCAGCAAGAAATGCACAaagattttgatttaaaaatagcaGGAAACCTTATTAATAAACCCGTCCCAATAACTACAGAAAATAACGAAACAGAAGCAAGTCCAATTTTAAGTCAGGACAATGTTCCGGTGGTTCCAACTCGAAGTGATGAAGAAGAAGACGAGGAAGGCCTGGTTGCGTCAACTAGTGAAGGAAATAATTCTGGAAGCGACGAAAACAAgtcGGAATCAGATACCGGCACACAACCACCGAAAAAGAAGTCTGCGTATAGCCTGGCACCAAACCGCGTATCCTGTCCCTACTGTCATCGTAAATTCCCTTGGTCCTCATCTCTCCGACGTCACGTCCTCACTCATACTGGCCAAAAGCCCTTCAAATGTCCCCACTGCCCGCTGCTGTTTACCACTAAATCTAACTGTGACCGCCACCTATTGAGGAAACATGGAGGATCAGCTAAAGCCATATTGGCTGAACCCATACAAGATCCCATAAATCCACAATCGACTGACAGAAGCGTACCAGAGAGACCATACAAATGCGCCACGTGTCCTACAAGTACATATTCTTCTAtggaaactttaaaaaaacacaTGGCCTCTAGACACGGTACTGGAGAATCTCAGCCAAGCTCTCCGAATCCTGAAGAAGAGGTCGATGGAAGTTTGGTCTTCAAGTGTCACCTTTGCGAGGGCTCATTTAGTGATAGGACGGCAGCTTTAGAACACTTGGCTTCGACGCATACATCTGAATATGAACAATTGGTCAGCAAGGGTGCCTTGGACGCCGCCAGTGACCGCAGTGAAAGTGCCGATGATGATGATAGGGGAAAATTTCCTGACCATGCAAATAGAAAGGTTGTCTGTGCGTTTTGCATTCGTCGTTTCTGGTCAGCAGAAGATTTGCGAAGACATATGAGGACTCATTCCGGTGAAAGGCCCTTCGCCTGTGACCTCTGCAGGCGACGGTTCACATTAAAACATTCGATGTTAAGACATAGAAAGAAGCATAAAGAAGAGACAGATGATGAAGAGTCACCAAGAGAAGATACAACTAATGGttATCGTTACCAAGAAGACGACGGTTCCGGTAACGAAATCCCAAGCAACGTTAACAACAACAATTCACCGCCCTCCGCGCCCTTTGACAAGAAACTTAAACTGGAAATGACATCGCGCAAATATTCGTCTGAAACAGAAAACGACGCTGAAAACGGTAGCGATCTTATTGGAAAGCTACTTGGTATACCCGATAAGACCATCATAAATAAGCTGTTATCCTCAGCGGACGAAGCCGCCAAATTCCTTGGAGTAAATAAATGA
Protein Sequence
MTVLIFLRPTRGRRKHLALTRSNKHSHRAEKLFVFVSIRIQEIKTEVISEAKIETDNQAMKIEEQETRATRTTSIDSDNRSDRSEEEECRRARKRAASTSASPIPLDKRTARFECPKCLQRFDSINTFDLHRFTAHGDDTRSGYDDYIDYSGKKFADILKNPHAEQRFRCEHCSRDFPSGQILDVHRKTCALSTRISSPDHDRREDFFAKLDLRNRSFGIPGTLTPPMDRFPSKFEDGHLTNGIRHIDAARDLADIQSILNVTSAGSLLERLTGTRVALENAVLTPPDTITKERETEETQDNFAAEFRRMKLRGEFPCRLCPAKFPNLRALKGHNRVHLSGTGPGPYQCNMCPHASLDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHAKVTREDVKRSIIYHPSEDPNNDEVNSKLTRDEVKRSLAFHTPESEKLREPTDRSTPLTHYNPSFIPDRHPVTSLNKSLPDSPALTPRESELPLPRIKVKGIGQLTQIPEFRTPDISFKVDVQPETYNEDTPVDLRTSDNNSCDVLDLSKKKRDTDNDEPKATSQPAFNSSTSVAATAAAAAAFEETRFILAQQRLLESSFPKMDSALYVNQLSQLYASAVPGLPGLPLPPSFPINPYILQPSFFPHPSDSPEIAEIKSRIQKEIIRGLSMSGGRLVNTETENQLKKEPEEEEQKPIQVSTTPTPPPHSESPLPITNVISQNDSVKMVIKNGILMPKQKQRRYRTERPFSCSQCSARFTLRSNMERHVKQQHPHHWSVRRPATRAPPPYPTNDTLADRVKYALLARQLERPITSDRSPVRRDSDEVADNEEDEDDTLVIDEEPEDQKADERSAAHRAAAEILMATRQQEMHKDFDLKIAGNLINKPVPITTENNETEASPILSQDNVPVVPTRSDEEEDEEGLVASTSEGNNSGSDENKSESDTGTQPPKKKSAYSLAPNRVSCPYCHRKFPWSSSLRRHVLTHTGQKPFKCPHCPLLFTTKSNCDRHLLRKHGGSAKAILAEPIQDPINPQSTDRSVPERPYKCATCPTSTYSSMETLKKHMASRHGTGESQPSSPNPEEEVDGSLVFKCHLCEGSFSDRTAALEHLASTHTSEYEQLVSKGALDAASDRSESADDDDRGKFPDHANRKVVCAFCIRRFWSAEDLRRHMRTHSGERPFACDLCRRRFTLKHSMLRHRKKHKEETDDEESPREDTTNGYRYQEDDGSGNEIPSNVNNNNSPPSAPFDKKLKLEMTSRKYSSETENDAENGSDLIGKLLGIPDKTIINKLLSSADEAAKFLGVNK*