Basic Information

Insect: Drosophila algonquin
Gene Symbol: RREB1
Assembly: GCA_035041765.1
Location: JAWNKY010000339.1:235670-241675[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.034 2.8 8.8 0.8 1 21 235 255 235 257 0.93

2 12 0.00024 0.019 15.5 0.2 1 23 267 289 267 289 0.98

3 12 7.6e-05 0.0063 17.1 7.3 1 23 295 317 295 317 0.98

4 12 0.6 49 4.8 3.8 2 19 562 579 562 581 0.97

5 12 0.038 3.2 8.6 0.0 1 23 726 748 726 748 0.97

6 12 1.2e-05 0.00096 19.7 0.7 1 23 758 780 758 780 0.99

7 12 0.00078 0.065 13.9 2.0 1 23 786 809 786 809 0.97

8 12 0.0028 0.23 12.2 2.0 1 23 1089 1112 1089 1112 0.95

9 12 8.1e-05 0.0067 17.0 0.3 2 23 1508 1529 1507 1529 0.97

10 12 0.14 11 6.8 6.3 1 23 1535 1558 1535 1558 0.97

11 12 0.011 0.93 10.3 0.6 3 23 1757 1777 1755 1777 0.95

12 12 0.0013 0.1 13.2 4.8 1 23 1783 1805 1783 1805 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.034	2.8	8.8	0.8	1	21	235	255	235	257	0.93
2	12	0.00024	0.019	15.5	0.2	1	23	267	289	267	289	0.98
3	12	7.6e-05	0.0063	17.1	7.3	1	23	295	317	295	317	0.98
4	12	0.6	49	4.8	3.8	2	19	562	579	562	581	0.97
5	12	0.038	3.2	8.6	0.0	1	23	726	748	726	748	0.97
6	12	1.2e-05	0.00096	19.7	0.7	1	23	758	780	758	780	0.99
7	12	0.00078	0.065	13.9	2.0	1	23	786	809	786	809	0.97
8	12	0.0028	0.23	12.2	2.0	1	23	1089	1112	1089	1112	0.95
9	12	8.1e-05	0.0067	17.0	0.3	2	23	1508	1529	1507	1529	0.97
10	12	0.14	11	6.8	6.3	1	23	1535	1558	1535	1558	0.97
11	12	0.011	0.93	10.3	0.6	3	23	1757	1777	1755	1777	0.95
12	12	0.0013	0.1	13.2	4.8	1	23	1783	1805	1783	1805	0.99

Sequence Information

Coding Sequence: atgcTAGcagcgcagcaacagcagcagcagcagccaccccaGCCACACAGCagtgccaccgccgcctccgTCACACAGGCTGCGATGGAGCGCCAGCGGCGCGAGTCCACCACATCGGAGTCCTCGCTGGAGCATCTCGACCTTGGCCGCACACCAAAGAagcttagcagcagcagcggcccaCAGCCCACATCGACGCCGCACGACACGGTCACAGCGTCCGCGGTGGTGTCAGCGTCGCGCAAGCGGAAGCTGCgacagcaccaacaacagcagcagcagcaggatctgctcagcgacgacgaggaggaggaggagctgcgtCCGCTGGAGGAGACGATGGCAGTGCAACGGCCGCGCCACAAGCAGCGACGCAACGGCCCCGCCTCCGCGGCGGCGGCCAGCGCTAGCATTGTGATGGACTACAGTGCCGGCGATGCCAGTTCGCTGCGCAAGAAGTTCCGGCTGAACCGCAGCGGCGCCAATGGAGATCTCTCGGAGTCCGGATTCGTCGATGCCAGCAGCTACAACAACAGCCATGCCGCAGCGGCCGCCGTCTCTGCTGCAGCGCAGCAGGCGTCGAAtgcctccagcagcagcagtagcagcagtggcagcggcagctcggGCGCCTCCTCGCCAGAGGGCCTGTGCCTGTCCAGCGGCGAGTCCGGCATCGGGGCTGGCGACGAGCACATGAAGTACCTTTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTCACCAACCACATCAGGTGCCACAACTACGCCAACGGCGACACCGAGAACTACACCTGCCGCATCTGCTCCAAGGTGCTCTCCTCGGCCTCATCGCTAGACAGACACGTGCTGGTGCACACGGGCGAGCGTCCGTTCAACTGCCGCTACTGCCACCTGACCTTCACCACCAACGGCAACATGCACCGCCACATGCGCACCCACAAGCAGCACCAGTCGACGACGTCGGCAGCGCAGCAATCGGCTTCGCAGAGcgccagcggcggcggcggcggcggcggctctctgtcgcagtcgcagcagcagcgacgcctctcacagcagcagcagcagcaacaccagcagcagttgttgtcgcagcagcagcaccagggtGGTGCAGCAGGTCATCCGGGACGTGCGGAGAGCTATGAGAGCGATGCCAGCTGTTCCACGGATGTTTCCAGtgcccacagccacacccatAGCCATGGGAGTAGTCACGCCCGCTCCcgcgcccacgcccacgcccactcccacaccaacaacaacaacaatcccCATAAAGcgaacaacaaccacaaggagatgcagcagcagcagatgcaggaGCGGATCAAGCAGCGTCGCCCCAAGACcaccatcaacaacaacatcatcgACGATGGCTCCCACGCGGAGGAGGACGAAGAGGAGCGCGACGAtcgggagggggaggaggagcatcACGATCCGGACACCGAAGATGATGTGGCCATGCCCCTCTCCATTACGAGCACCCCGGATGTAGCCACCCTGCTGGCCGGAGTCAATGCATCCTCGCGGGCTGCCTCGCGCTCCCGCTCACCCTCGCCGGCCATGCCCCTGTTGAGTTGCCCTGCTTGTGGCGCCTCCGACTTTGATTCGCTGCCAGGGCTGTGCGCCCACCTGGACGCCCGACACTCGGACATACCCGCCAAGTGCCGCGACTGTGACGTGATCTTCGCCAGCCACCGCCAGCTGCAGGCGCACTGCTGCCGCGGCCTGGTGGGGGTGGATCTGCCGCCTCTCCTGGGGGCCAGCAGCTCACCGCTGCACCAGggcgaggatgaggacgacgaGGATGCCGAGGACGAGGCCAGGACCGAGAGGGAGGCCGAACAGCACGGGGACTTCTTCCAGCAGCTGTACCTCAAGAGCAAGGCAGCCGCTTCCGCTGTCGCCGGGGCATCCACCTCCTCGCCCCCGTCCCCCATCAAGCACGAGCCGGCGGACAGCAAGGATCTGGCTGACATCCAGAGCATCCTCAACAtgaccagctccagctgcaccTCCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAGTACAGCCTCGACGGCCGcgaccaggaggaggaggcccaAGATGTCTTCACCTCGGAGTTCCGCCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGTGCGGCAGTGTTCCCCAATCTGCGCGCCCTCAAGGGCCACAACCGGGTGCACCTCGGCTCCGTTGGCCCCTCCGGCCCGTTCCGTTGCAACATGTGTCCGTATGCCGTCTGCGACAAGGCCGCCCTCGTCCGTCACATGCGCACCCACAACGGGGACCGACCGTACGAGTGCGCCGTCTGCAATTACGCCTTCACCACGAAGGCCAACTGCGAGCGGCATCTGCGCAACCGGCACGGCAAGACCAGTCGCGAGGACGTGAAGCGGGCCATCGTCTACCATCCGGCGGAGGACGCCAGCTGCGAGGACAGCAAGTCGCGCCTGGGACTCGGCGATGATCTGGCCGATCTGAGCTTCCGCTCGGTGTCGCCGcccccaccgccgccgccggcccCAACCAGTGCTCCGATTACCGAGGGCTCACAACTGAAGCACATGCTCCTGGGAGAGCCGTCGCCACCATTGCATACTCCCACAGtgtccgctgctgctgctgttgccggaCCCCCATCTAAGATCCAGGTGAAGAGCCTCGACCAGCTGGTGGACAAGAAACAGCCTGCCGCTGGCCCTGCCCTCGACTTTAGCATGGATGTGCTGGATCTCAGCAAGAAGCCCAACACTGGAGGATCAGCCTCGGcttctgcctccgcctctgcctcgtCGGCCCCCTCAACGGTGCCAGAACTGGCTGCCGttctggagcagcagcaacaacaacaacagcagcagcaacagctgctcctggcccagcagcagctctttgGTGGTGCAGCCGGagcagcgggagcagcagGCGATGCCGCCTCCCAGTACATGCAGCAGCTGTTCCGCAACCTGATGTTCCAGACACAGACGCCGGGCTTTCCCTTCTTCGGATTCATGGCCCCGCCTCCACCACAAGGCAGTGCCGAGAAGCCGCCGCAGCTGAGTCCGCCATCGCGGATGggggccctgcccctgccgatGCCAGTGGGCGTGCCCGTTCCGTCTGGCGGCCCCGTCAAGATGGTCATCAAGAACGGAGTGCTGATGCCCAAACAGAAGCAGCGCCGCTACCGCACCGAACGGCCCTTCGCCTGCGAGCACTGCTCGGCCCGCTTCACCCTGCGCTCCAACATGGAGCGTCAcgtgaagcagcagcatccccagTTCTATGCCCAGCGCCAGCGGAGCGGACACCACGTGATGCGCGGACGCGGTGCCTCCAACGCCGCAGCGGCCGtggccgcagccgccgccgcagcggcagccatgAGCCAGGGCGGATCCGGATCGGGCCATGTGCACGGCCATGCCCCCATCTCGGAGCAGGTGAAGTACGCCATCTTGGCGCAACAGCTGAAGTCGCACAAGAACACGGATCTGCTGCAGCAGGCTCTGGCCCACGGATCCAGCAACGTGGCCGGTGGCAATCCCCTCCTGCCCTTTGGCTATGGCCCACCCCAGACGCAGTCGCACtcccagtcacagtcccacAACCACACCGCAtcccagtcccactcccagtcccagtcgagTACCCATGGCCATGTTCAGTCCAGTTCTGGCTCCCATCTGCCGCATCTGGTGAATGGGATCCACAATGGGAGCAATGGAAACAACGGCCAGGCGAGTGCCATCGATGACGACGAGCCCAAGCTGATCAttgacgaggatgaggatggcgAGGGCGATGTGGAGGAGTTcgacgaggacgatgaggaggaggaggatgagccCGAGGACGAGGACCCGGAGCCCGAGCCAATGGAAGAGCCGGAACAGGTGCACGACGAGGAGCCAGAGGACGAGGATCAGGAGCTGCCCAAGCCCCTGGAGCACATCTCACAGCCCAGTGCTGCAGCGGCCAATGAGGCGGCCAAGAAGATGGCCGAGACAATTCTCGAGCAGGCCATCAAGGCGGGCAAGGCCACGCCCACTGCCACGCCCATAAGCACGCGCACGCCGTCACCCAGTCCGGAGTCGACGAACAACGCCATGCCGGAGCCGAGTCCCCCGAATCCCACCATGAAGTCGATGATCGCCCAAGCCGAGTCGGTGGCCAAGTCTCTGAAGGAGGTCGCCAGCTCTCCGTTCAAGGACGAGTCGCAGGACCTAGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCAGCCAGATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGATGAGGAGGGTCTCGTGGCCTCCGGCAGCGCCAGCGAGAGCAACAATTCAGGAACGGAAGAcgtcaccagcagcagttccgGCAGCGAACCGAAGAAGAAGTCCGCCTACAGCCTGGCCCCCAATCGCGTCTCGTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGACGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCACTGCTCTTCACCACCAAGAGCAACTGCGACCGCCATCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTAGAGGAGATCGAGCTCGAGGAGCAGCGTCGTCGCCAGGAGGCGGAGAGGGAGCGCGAACGCGAGcgggagctggaactggaacggGAGCGCGAGAAGGAGCTGGAGCGCGAACGAGAACTGGAGCGGGAGCGCGAGCGCGAGAAGGAGCGTCTGGTGCTCATCCAGAAGCTGGCGGCTCAGATGAATGCCGCCGcagcggccgctgctgctgcctcggcTACCGATGCCGGCGCTGGCGGAGATCTGCCGTACAAGTGCCACCTGTGCGAGGGCTCCTTTGCCGAGCGTCTGCACTGCCTCGAGCACATCAAGCAGACGCATGCCCACGAGTttgccctgctgctggccaagggAGCCATCGAGCCGGAGTCCCGTGCCGGGGAGTCCAACCAccagcagctcctccaacagcagcagagcaccCCGGGTGCCGGTTCCGACGATGAGGcgagtggcggtggcggtgcaCGCGGTGCCTCTGGCAAATATCCGGACTACAGCAACCGGAAGGTGATCTGCGCCTTCTGTCTGCGCCGTTTCTGGTCCACCGAGGACCTGCGCCGGCACATGCGCACCCATTCCGGGGAGCGGCCGTTCCAGTGCGAGATCTGCCTCCGCAAGTTCACCCTCAAGCACAGCATGCTGCGTCACATGAAGAAGCACAGCGGACGCGCCCACAACGGCGACAATCCCGGCTCCGACTGTTCCGACGATGAGCAGGTCGCCACTCCACCATCCACCCCAGGACCCACTCCggccacccccaccaccaacaacaacaacagttgccagaacaacaacaacaacagcagcaacaccaacgcCAATGCAAAGATGAGCCTGCGTCTGCCGAAGCTGCACGAGCTGCTGGACAAGTCGAGCGAGTGGCGGACCAGCCGGCTGGGCGAGCACAAGGAGAACATCGGCGAGGCGGcaacaccatcagcagcagcggtggccaGCTCCGATCTGATCGGAAATCTCCTGGGCATCAGCGACCAGGGCATACTCAACAAGCTGCTCTCATCCGCCGACGAGGCGGCCAAGTTCCTGGGCGTGGACAACAAGTAG
Protein Sequence: MLAAQQQQQQQPPQPHSSATAASVTQAAMERQRRESTTSESSLEHLDLGRTPKKLSSSSGPQPTSTPHDTVTASAVVSASRKRKLRQHQQQQQQQDLLSDDEEEEELRPLEETMAVQRPRHKQRRNGPASAAAASASIVMDYSAGDASSLRKKFRLNRSGANGDLSESGFVDASSYNNSHAAAAAVSAAAQQASNASSSSSSSSGSGSSGASSPEGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENYTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQSTTSAAQQSASQSASGGGGGGGSLSQSQQQRRLSQQQQQQHQQQLLSQQQHQGGAAGHPGRAESYESDASCSTDVSSAHSHTHSHGSSHARSRAHAHAHSHTNNNNNPHKANNNHKEMQQQQMQERIKQRRPKTTINNNIIDDGSHAEEDEEERDDREGEEEHHDPDTEDDVAMPLSITSTPDVATLLAGVNASSRAASRSRSPSPAMPLLSCPACGASDFDSLPGLCAHLDARHSDIPAKCRDCDVIFASHRQLQAHCCRGLVGVDLPPLLGASSSPLHQGEDEDDEDAEDEARTEREAEQHGDFFQQLYLKSKAAASAVAGASTSSPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDQEEEAQDVFTSEFRRMKLRGEFPCKLCAAVFPNLRALKGHNRVHLGSVGPSGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEDSKSRLGLGDDLADLSFRSVSPPPPPPPAPTSAPITEGSQLKHMLLGEPSPPLHTPTVSAAAAVAGPPSKIQVKSLDQLVDKKQPAAGPALDFSMDVLDLSKKPNTGGSASASASASASSAPSTVPELAAVLEQQQQQQQQQQQLLLAQQQLFGGAAGAAGAAGDAASQYMQQLFRNLMFQTQTPGFPFFGFMAPPPPQGSAEKPPQLSPPSRMGALPLPMPVGVPVPSGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAVAAAAAAAAAMSQGGSGSGHVHGHAPISEQVKYAILAQQLKSHKNTDLLQQALAHGSSNVAGGNPLLPFGYGPPQTQSHSQSQSHNHTASQSHSQSQSSTHGHVQSSSGSHLPHLVNGIHNGSNGNNGQASAIDDDEPKLIIDEDEDGEGDVEEFDEDDEEEEDEPEDEDPEPEPMEEPEQVHDEEPEDEDQELPKPLEHISQPSAAAANEAAKKMAETILEQAIKAGKATPTATPISTRTPSPSPESTNNAMPEPSPPNPTMKSMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSSQMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERERELELEREREKELERERELEREREREKERLVLIQKLAAQMNAAAAAAAAASATDAGAGGDLPYKCHLCEGSFAERLHCLEHIKQTHAHEFALLLAKGAIEPESRAGESNHQQLLQQQQSTPGAGSDDEASGGGGARGASGKYPDYSNRKVICAFCLRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRAHNGDNPGSDCSDDEQVATPPSTPGPTPATPTTNNNNSCQNNNNNSSNTNANAKMSLRLPKLHELLDKSSEWRTSRLGEHKENIGEAATPSAAAVASSDLIGNLLGISDQGILNKLLSSADEAAKFLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00601282; iTF_00517956; iTF_00575077; iTF_00564170; iTF_00481069; iTF_00536271; iTF_00515122; iTF_00581010; iTF_00603575; iTF_00484632; iTF_00471868;
90% Identity: iTF_00517956; iTF_00575077; iTF_00481069; iTF_00536271; iTF_00581010; iTF_00471868;
80% Identity: -