Basic Information

Insect: Drosophila persimilis
Gene Symbol: RREB1
Assembly: GCA_003286085.2
Location: NW:1706139-1716569[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.035 1.9 8.7 0.8 1 21 238 258 238 260 0.93

2 12 0.00024 0.014 15.5 0.2 1 23 270 292 270 292 0.98

3 12 7.8e-05 0.0044 17.1 7.3 1 23 298 320 298 320 0.98

4 12 0.61 34 4.8 3.8 2 19 564 581 564 583 0.97

5 12 0.039 2.2 8.6 0.0 1 23 732 754 732 754 0.97

6 12 1.2e-05 0.00067 19.6 0.7 1 23 764 786 764 786 0.99

7 12 0.0008 0.045 13.9 2.0 1 23 792 815 792 815 0.97

8 12 0.0029 0.16 12.1 2.0 1 23 1096 1119 1096 1119 0.95

9 12 8.3e-05 0.0047 17.0 0.3 2 23 1516 1537 1515 1537 0.97

10 12 0.14 7.9 6.8 6.3 1 23 1543 1566 1543 1566 0.97

11 12 0.012 0.65 10.2 0.6 3 23 1764 1784 1762 1784 0.95

12 12 0.0013 0.073 13.2 4.8 1 23 1790 1812 1790 1812 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.035	1.9	8.7	0.8	1	21	238	258	238	260	0.93
2	12	0.00024	0.014	15.5	0.2	1	23	270	292	270	292	0.98
3	12	7.8e-05	0.0044	17.1	7.3	1	23	298	320	298	320	0.98
4	12	0.61	34	4.8	3.8	2	19	564	581	564	583	0.97
5	12	0.039	2.2	8.6	0.0	1	23	732	754	732	754	0.97
6	12	1.2e-05	0.00067	19.6	0.7	1	23	764	786	764	786	0.99
7	12	0.0008	0.045	13.9	2.0	1	23	792	815	792	815	0.97
8	12	0.0029	0.16	12.1	2.0	1	23	1096	1119	1096	1119	0.95
9	12	8.3e-05	0.0047	17.0	0.3	2	23	1516	1537	1515	1537	0.97
10	12	0.14	7.9	6.8	6.3	1	23	1543	1566	1543	1566	0.97
11	12	0.012	0.65	10.2	0.6	3	23	1764	1784	1762	1784	0.95
12	12	0.0013	0.073	13.2	4.8	1	23	1790	1812	1790	1812	0.99

Sequence Information

Coding Sequence: ATGCTGGCAGCAcagctacagcagcagcagcagccccccCAGCCACACAGCAGTGCCACCGGCGCCGACACGCAGGCAGCGATGGATCGCCAGCGACGCGAGTCCACCACATCGGAGTCCTCGCTGGAGCACCTCGACCTCGGCCGCACACCAAAGaagctgagcagcagcagcggcccaCAGCCCACATCGACGCCGCACGACACGGCCACAGCGTCGGCGGTGGTGTCGGCGTCGCGCAAGCGCAAGCTGcgacagcaccaacagcaacagcagcagcagcaggatctGCTCAgcgacgacgaggaggaggaggagccgcGTCCGCTTGAGGAGACGATGGCAGTGCAGCGGCCGCGCCACAAGCAGCGACGCAACGGCACCGCCTCCGGGGCGGCGGCCAGCGCCAGCATCGTGATGGACTACAGTGCCGGCGACGCCAGTTCGCTTCGCAAGAAGTTCCGGCTGAACCGCAGCGGTGCCAACGGCGACCTCTCCGAGTCCGGGTTCGTCGACGCCAGTAGCTACAACAACAGCCATGCCGCATCGGCCGCCGTCTCTGCTGCAGCGCAGCAGGCGTCGAATGcctccagcaccagcagcagcaacagcagtggcagcggaAGTGGCAGCTCTGGCGCCTCCTCGCCGGAGGGCCTGTGCCTGTCCAGCGGCGAGTCCGGAATCGGGGCTGGCGACGAGCACATGAAGTACCTCTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTTACCAACCACATCAGGTGCCACAACTACGCCAACGGCGACACCGAGAACTATACCTGCCGCATTTGCTCCAAGGTGCTATCCTCGGCCTCGTCGCTGGACAGACACGTGCTGGTGCACACAGGCGAGCGTCCGTTTAACTGCCGCTACTGCCACCTGACCTTCACCACCAACGGCAACATGCACCGCCACATGCGCACCCACAAGCAGCACCagtcgacgacgacgacgtcggCGGCGCAGCAGTCGGCTTCGCAGAGCGCCGGCAGCGGCTCTCTGTCgcaggcgcagcagcagcgacgcctgtcacagcagcagcaacagcagcaacagtcgCTGTCgcagaaccagcagcaggGAGGTGCAGGGCATCCGGGACGTGCGGAGAGCTATGAGAGCGATGCCAGCTGCTCCACGGATGTATCCAGTGCCCACAGCCACACCCACAGCCATGGGAGTAGTCACGCCcgcgcccacgcccacgcacacagcaacaacaaccacaacaacaacaacaacaacaacaacaatcccCACAAAGCGAACAACAACCACAAggagatgcagcagcagatccAGGAGCGGATCAAGCAGCGTCGCCCCAAGACCaccatcaacaacaacaacatcatcGACGAGGGCTCccaggcggaggaggaggaggatcgTGATCGGGAGGAGCAGgaccaggaggaggagcaccCCGATGCGGACACTGACGATGATGTGGCCATGCCCCTCTCCATTACGAGCACCCCGGATGTGGCCACCCTGCTGGCCGGAGTCAATGGATCCTCGCGGGCAGCCTCGCGCTCCCGCTCCCCCTCGCCGGCCATGCCCCTGCTGAGCTGCCCCGCCTGTGGTGCCTCCGACTTTGACTCGCTGCCAGGGCTGTGCGCCCACCTGGACGCCCGCCACTCGGACATACCCGCCAAGTGCCGCGACTGCGACGTGATCTTCGCCAGCCACCGCCAGCTGCAGGCGCACTGCTGCCGCGGCCTGGTGGGCGTGGATCTGCCGCCGCTCCTGGGGGCCAGCAGCTCACCTCTGCACCACAGCGAGGACGAGGATGAAGAGGATGCTGACGACGAGGCGAGGACCGAGAGGGAGGCGAAACAGCACGAGGACTTCTTCCAGCAGCTGTATCTCAAGGGCgaggcagccgcagccgcagccgctgccgcAGCCGCCGGGACATCCACCTCCTCTCCACCGTCCCCCATCAAGCACGAGCCGGCGGACAGCAAGGACCTGGCGGACATCCAGAGCATCCTGAACATgaccagctccagctgcaCCTCCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAGTACAGCCTCGACGGCCGCgaccaggaggaggaggcccaGGACGTCTTCACCTCGGAGTTCCGACGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCGCGGCAGTGTTCCCCAATCTGCGCGCCCTCAAGGGCCACAACCGGGTGCATCTCGGCTCCGTCGGCCCCTCCGGCCCGTTCCGCTGCAACATGTGTCCGTATGCCGTCTGCGACAAGGCCGCCCTCGTGCGTCACATGCGCACCCACAACGGGGACCGGCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGGCACCTGCGCAACCGTCACGGCAAGACCAGTCGCGAGGACGTGAAGCGGGCCATCGTCTACCATCCGGCGGAGGATGCCAGCTGCGAGGACAGCAAATCGCGCCTGGGGCTCGGCGATGATCTGGCCGATCTGAGCTTCCGCTCGGTCTCGCCGCCAcccccgccgccgccacccCCAGCTAGTGCTCCGATTGCCGAGGGCTCTCAGCTGAAGCACATGCTCTTGGGAGAGCCGTCGCCTCCATCGCACACCCCCACggtggccgctgctgctgctgctgttgccgggCCACCATCCAAGATCCAGGTGAAGAGCCTCGACCAGCTGGTGGACAAGAAGCAGCCTGCCGCAGGCCCTGCCCTCGACTTTAGCATGGATGTGCTGGATCTCAGCAAGAAGCCAACAACAGGAGGATCCTCCACCGCCTCCGCTCCGTCGGGCCCGTCAACGGTGCCAGAGCTGGCAGCCGTcctggagcagcagcagcagcaacagcaacagcaacagcaacagcagcaacaacagctgctgctggcacaACAGCAGCTCTTTGGAGGAGCAGCCGGAGCGGCGGGAGCTGGCGATGCCGCTTCCCAGTACATGCAGCAGCTGTTCCGCAACCTGATGTTCCAGTCGCAGACGCCGGGCTTTCCCTTCTTTGGATTCATGGCCCCGCCGCCACCACAAAGCAATCCCGAGAAGCCGCCGCAGCTGAGTCCGCCTACGCGGATGGGCGCCCTGCCCCTGCCGATGCCAGTGGGCGTGCCCGTGCCGCCTGGCGGCCCCGTCAAGATGGTCATCAAGAACGGAGTGCTGATGCCCAAGCAGAAGCAGCGCCGCTACCGCACCGAGCGGCCCTTCGCCTGCGAGCACTGCTCCGCCCGCTTCACGCTGCGCTCGAACATGGAGCGCCACGTGAAGCAGCAGCATCCCCAGTTCTACGCCCAGCGGCAGCGGAGCGGACACCACGTGATGCGCGGTCGCGGAGCCTCCAATGCCACAGCAGCCgtggcagcagccgccgccgcagcgGCAGCCATGAGCCAGGGCGGATCCGGAGCGGGCCATGGGCACGGCCATGCCCCCATCTCGGACCAGGTGAAGTACGCCATCCTGACGCAACAGCTGAAGGCGCACAAGAACACGGATCTGCTGCAGCAGGCGCTGGCCCACGGATCCAGCAGCGTGGCCGGTGTCAATCCCCTCCTGCACTTTCCCTATGGCGCACCCCAGGCGCAgttccactcccactcccagtcgcagtcccagtcccactcccactcccattcGCAGTCGAGTAGCCATGGCCACGCCAGTTCTGGGTCCCATCTGCCGCATCTGGTGAACGGGATGCACAATGGGCAGAACAACGGCCAGGCGAGTGCCATCGATGACGACGAACCCAAGCTGATCATTGACGAGGATGAGGATGGCGAGGGCGATATTGAGGAGTTCGACGAGgacgaagaggaggaggaggacgagccCGAGGACGAGGACCCGGAGCCAGAGGCAACGGAAGAGCCGGAGCAGGCCCACGACGAGGAGCCAGAGgacgaggagcaggagctgccCAAGCCCCTGGAGCACATCTCCCAGACCAGTGCAGCGGCCAAGGAGGCGGCCAAGGAGGCGGCCAAGAAGATGGCCGAGACCATCCTCGAGCAGGCCATCAAGGCGGGCAAGGCCACGCCCagcgccactgccactggcacgcCCATGAGCACGCGAACGCCGTCGCCCAGTCCGGAGCCGACGAGCAACGCGATGCCGGAGCCGAGTCCGCCGAATCCCACCATGAAGTCGATGATCGCCCAGGCCGAGTCGGTGGCCAAGTCCCTGAAGGAGGTCGCCAGCTCCCCTTTCAAGGACGAGTCGCAGGACCTGGTGCCGGTGGCCAAGCTGGTAGACAACGCCACCAGCAGCCAGATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTCGTGGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGAACGGAGGacgtcaccagcagcagctccggCAGCGAGCCGAAGAAGAAGTCCGCCTACAGCCTGGCCCCCAATCGCGTCTCCTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGTAGCTCGCTGCGGCGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACCAAGAGCAACTGTGACCGCCATCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATACCAGTGCCCAAGTCTGTGGAGGAGATCGAGCTGGAGGAGCAGAGACGCCGCCAGGAGGCGGAGAGGGAGCGCGAACGCGAGCGGGagctggaactggagctggagcgggagcgggagcgcgAGAAGGAGCTGGAGCGCGAACGCGAGCTGGAGCGGGAGCGCGAGCTCGAAAAGGAGCGCCTGGTGCTCATCCAGAAGCTGGCGGCTCAGATGAATGCGGTCGCTGCTGCCTCGGCGGCCGATGCCGGCGCTGGCGGAGATCTGCCGTACAAGTGCCACCTGTGCGAAGGCTCCTTCGCCGAGCGTCTGCACTGCCTCGAGCACATCAAACAGTCGCATGCCCACGACTTTGCCCTGCTCCTGGCCAAGGGAGCCATCGAGCCGGAGTCCCGTGCCGGGGAGTCCAACCACCAGCATctcctgcagcagcagagcacCCCGGGGGCCGGCTCCGACGATGAGGcgagcggcggcggcggtgcaCGCGGAGCCTCTGGCAAATATCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTTTGCCTGCGCCGCTTCTGGTCCACCGAGGACCTGCGCCGCCACATGCGCACCCACTCCGGGGAGCGGCCGTTCCAGTGCGAGATCTGCCTCCGCAAGTTCACCCTCAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGTGGACGAGCCCACAACGGCGACAATCCTGGCTCCGACTGCTCCGACGATGAGCAGGTCGCCACTCCTCCATCCACCCCAGGACCCActccggcaccggcaccggcaccggccaCCGGCACCACCCCCACTCccaccaacaacaataacagttgccagaacaacaacaacaacaacagcaacaccaacgCCAATGCAAAGATGGGTCTGCGCCTGCCGATGCGGCACATGCTGCTGGACAATTCGAGCGAGTGGCGGGCCAGCCGCCTGGGCGAGCACAAGGAGAACATCGGAGAGGCGGCAACCCCGTCAGCCGCGGCGGTGGCCAGCTCCGATCTGATCGGAAATCTCCTGGGCATCAGCGACCAGGGCATACTCAACAAGCTGCTCTCCTCCGCCGACGAGGCGGCCAAGCTCCTGGGAGTGGACAACAAGTAG
Protein Sequence: MLAAQLQQQQQPPQPHSSATGADTQAAMDRQRRESTTSESSLEHLDLGRTPKKLSSSSGPQPTSTPHDTATASAVVSASRKRKLRQHQQQQQQQQDLLSDDEEEEEPRPLEETMAVQRPRHKQRRNGTASGAAASASIVMDYSAGDASSLRKKFRLNRSGANGDLSESGFVDASSYNNSHAASAAVSAAAQQASNASSTSSSNSSGSGSGSSGASSPEGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENYTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQSTTTTSAAQQSASQSAGSGSLSQAQQQRRLSQQQQQQQQSLSQNQQQGGAGHPGRAESYESDASCSTDVSSAHSHTHSHGSSHARAHAHAHSNNNHNNNNNNNNNPHKANNNHKEMQQQIQERIKQRRPKTTINNNNIIDEGSQAEEEEDRDREEQDQEEEHPDADTDDDVAMPLSITSTPDVATLLAGVNGSSRAASRSRSPSPAMPLLSCPACGASDFDSLPGLCAHLDARHSDIPAKCRDCDVIFASHRQLQAHCCRGLVGVDLPPLLGASSSPLHHSEDEDEEDADDEARTEREAKQHEDFFQQLYLKGEAAAAAAAAAAAGTSTSSPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDQEEEAQDVFTSEFRRMKLRGEFPCKLCAAVFPNLRALKGHNRVHLGSVGPSGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEDSKSRLGLGDDLADLSFRSVSPPPPPPPPPASAPIAEGSQLKHMLLGEPSPPSHTPTVAAAAAAVAGPPSKIQVKSLDQLVDKKQPAAGPALDFSMDVLDLSKKPTTGGSSTASAPSGPSTVPELAAVLEQQQQQQQQQQQQQQQQLLLAQQQLFGGAAGAAGAGDAASQYMQQLFRNLMFQSQTPGFPFFGFMAPPPPQSNPEKPPQLSPPTRMGALPLPMPVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNATAAVAAAAAAAAAMSQGGSGAGHGHGHAPISDQVKYAILTQQLKAHKNTDLLQQALAHGSSSVAGVNPLLHFPYGAPQAQFHSHSQSQSQSHSHSHSQSSSHGHASSGSHLPHLVNGMHNGQNNGQASAIDDDEPKLIIDEDEDGEGDIEEFDEDEEEEEDEPEDEDPEPEATEEPEQAHDEEPEDEEQELPKPLEHISQTSAAAKEAAKEAAKKMAETILEQAIKAGKATPSATATGTPMSTRTPSPSPEPTSNAMPEPSPPNPTMKSMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSSQMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERERELELELEREREREKELERERELERERELEKERLVLIQKLAAQMNAVAAASAADAGAGGDLPYKCHLCEGSFAERLHCLEHIKQSHAHDFALLLAKGAIEPESRAGESNHQHLLQQQSTPGAGSDDEASGGGGARGASGKYPDYSNRKVICAFCLRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRAHNGDNPGSDCSDDEQVATPPSTPGPTPAPAPAPATGTTPTPTNNNNSCQNNNNNNSNTNANAKMGLRLPMRHMLLDNSSEWRASRLGEHKENIGEAATPSAAAVASSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00474019;
90% Identity: iTF_00474019;
80% Identity: -