Dsub000879.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila subsilvestris
Gene Symbol
RREB1
Assembly
GCA_035043285.1
Location
JAWNNB010000133.1:5695138-5701263[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.038 2.7 8.7 0.8 1 21 248 268 248 270 0.93
2 12 0.00026 0.019 15.5 0.2 1 23 280 302 280 302 0.98
3 12 8.6e-05 0.0062 17.0 7.3 1 23 308 330 308 330 0.98
4 12 0.24 17 6.2 2.0 2 20 571 589 571 591 0.93
5 12 0.043 3.1 8.5 0.0 1 23 739 761 739 761 0.97
6 12 1.3e-05 0.00094 19.6 0.7 1 23 771 793 771 793 0.99
7 12 0.00088 0.063 13.9 2.0 1 23 799 822 799 822 0.97
8 12 0.0031 0.23 12.1 2.0 1 23 1122 1145 1122 1145 0.95
9 12 9.1e-05 0.0066 17.0 0.3 2 23 1550 1571 1549 1571 0.97
10 12 0.15 11 6.8 6.3 1 23 1577 1600 1577 1600 0.97
11 12 0.013 0.91 10.2 0.6 3 23 1798 1818 1796 1818 0.95
12 12 0.0014 0.1 13.2 4.8 1 23 1824 1846 1824 1846 0.99

Sequence Information

Coding Sequence
ATGTTGGccgcacagcaacagcagcagccacacagcactgccaccgccacagccaccgccacagccaccgccactgccgccgTAGTCACGCAGGCAGCGATGGAGCGTCAGCGGCGCGAGTCCACCACATCGGAGTCCTCGCTGGAGCACCTCGACCTCGGCCGCACACCAAAgaagctgagcagcagcagcggcccaCAGCCCACATCGACGCCACACGACACGGCCCCAGCAGCGGCGGTGATGTCAGCGTCGCGCAAGCGCAAGCTGCGACAGCACCAAcagctccaacagcagcaacaggatcTGCACagcgacgacgaggaggaggaggaggaggaggagccacgTCCGCTGGAGGAGACGATGGCTGCTGTGCAGCGACCGCGCCACAAGCAGCGACGCAACGCCAACGCCTCTGCGGCGGCCAGTGCCAGCATCGTGATGGACTACAGTGCCGGCGACGCCAGTTCGCTGCGCAAGAAGTTCCGACTGAACCGCAGTGGCGCCGCCGCCAACGGCGACCTCTCCGAGTCCGGATTCGTGGACGCCAGCagctacaacagcagcagccaggccgCAGCGGCCGCCGTCTCTGCTGCAGCGCAGCAGGCGTCGAatgcctccagcagcagcagcagcaacagcagcggcagcggcagctcagGTGCCTCCTCGCCGGAGGGCCTCTGCCTGTCGAGCGGCGAGTCCGGCATCGGTGCCGGCGACGAGCACATGAAATACCTCTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTCACGAACCACATCAGGTGCCACAACTACGCCAACGGCGACACCGAGAACTACACCTGTCGCATCTGCTCCAAGGTGCTCTCCTCGGCCTCGTCACTGGACAGACACGTGCTGGTGCACACGGGCGAGCGTCCGTTCAACTGCCGCTACTGCCACCTGACCTTCACCACCAACGGCAACATGCACCGGCACATGCGCACCCACAAGCAGCACCAGTCGACGACGCAGTCGTCTGCAGCGGCGCAAAGCGGCGGctctcagtcgcagtcgcagcagcagcgacgcctgtcacagcagcagcatcagcagcagcagcaacagtcgcTGGCGCAGTCGCTGGCGCAGTCGCAGCATGGTGGTGGCGCAGGGCATCCGGGACGTGCGGAGAGCTATGAGAGCGATGCCAGCTGCTCCACGGATGTGTCCAGTGCCCACAGCCAtgggagcagcaacaacaacaacaacaacaacaacaatccacACAaagcgaacaacaacaacagcagcagcagcatcagccacagccacaagcagcagctgcagctgcagatccAGGAGCGGATCAAGCAGCGTCGCCCCAAGACcaccatcaacaacaacaacaacaacaacatcatcatggACGAGGGCTCccaggcggaggaggaggaggaggatgctgATGTGGAGGAGCGGGACATGAAGGAGGAGCAACCCGATCCAGACACCGACGAGGATGTGGCCATGCCCCTGTCCATAACCAGCACACCGGATGTGGCCACCCTGCTGGCCGGAGTCAGTGCATCCTCGCGCGCCGAATCGCGCTCCCGCTCCCCCTCGCCGGCCATGCCCCTGCTGAGCTGCCCCGCCTGTGGCGCCTCCGACTTTGACACGCTGCCCGGTCTGTGCGCCCATCTGGACGCCCGCCACTCGGACATACCCGCCAAGTGCCGCGACTGCGAGGTGATCTTCGCCAGCCACCGCCAGCTGCAGGCGCACTTCTGCCGCGGCCTGGTGGGCGTCGATCTGCCGCCGATGCTGGGTGCCAGCAGCTCGCCGCTGCACCAGGGCGACGACGAGGATGACGAGGAGGCCGAGGACGAGGACAAGGACGAGGCCAGGACCGAGCGGGAGGCGGAGCAGCGGGACGAGTTCTTCCAGCAGCTGTACCTCAAGGGCAAGGCAGCCgccgcggcagcagctgccgccggGGCATCGTCGCCGCCGTCGCCCATCAAGCACGAGCCGGCGGACAGCAAGGATCTGGCCGACATCCAGAGCATCCTGAACAtgaccagctccagctgcaccTCCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAGTACAGCCTCGATGGGCGCgaccaggaggaggaggcccaGGACGTCTTCACCTCCGAGTTCCGACGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTGTGCGCGGCCGTGTTCCCCAATCTGCGCGCCCTCAAGGGCCACAACCGTGTGCACCTCGGCTCCGTGGGCCCCTCCGGCCCCTTCCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCCGCCCTCGTGCGCCACATGCGCACCCACAACGGCGACAGGCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGGCACCTGCGCAACCGGCACGGCAAGACCAGTCGCGAGGATGTGAAGCGGGCCATCGTCTACCATCCGGCGGAGGATGCTAGCTGCGAGGACAGCAAGTCCCGGCTGGGGCTCGGCGACGATCTGGCCGATCTGAGCTTCCGCTCCATctcgccgccaccaccgccgccgccgccgccgccatcatcatcatgcagTGCTCCGATCGCCGAGGGCGGCTCACAGCTGAAGCACATGCTCCTGGGTGAGTCCTCGCCATCGCCACTCCCACACGCCCCCacagctgtggctgctgctgctgctgctgctgctgccggacCCCCGTCCAAGATCCAGGTGAAGAGCCTCGACCAGCTGGTGGACAAGAAACAGGAGAGCCCCGCGCTCGACTTCAGCATGGATGTGCTGGATCTCAGCAAGAAGccaacagcaggaggagcatctgcctctggcttgggcttgggcttgggctcggGCTCGGCAGCGACGGCACCCGCAACGGTGCCAGAACTGTCAGCCGtcctggagcagcagcagcagcaacagcaacagcaacagcagctgctcctggcCCAGCAGCAGTTCTTTGGCGGCGCAGccggtgcagcagcagccggaggAGCAGGCGATGCCGCCTCCCAGTACATGCAGCAGCTGTTCCGCAACCTCATGTTCCAGTCGCAGACGCCGGGCTTTCCCTTCTTCGGTTTCATGGCGCCGCCGCCACCCCAAGGCAGTGCCGagaagcagccgcagctgaGTCCGCCCAACCGAATGGGCGGCCTGCCGCTGCCAATGCCAggggtgggcgtgggcgtgggcgtgccGGTGCCACCCGGCGGCCCCGTCAAGATGGTCATCAAGAACGGAGTGCTGATGcccaagcagaagcagcgccGCTACCGCACCGAGCGGCCCTTCGCCTGCGAGCACTGCTCCGCCCGCTTCACGCTGCGCTCCAACATGGAGCGGCAcgtcaagcagcagcatccccagTTCTATGCCCAGCGCCAGCGCAGCGGCCACCATGTGATGCGCGGACGCGGAGCCTCGAatgcagcggctgctgtggccgcagccgccgccgcagcggcagccatGAGCCAGGGCGGATCGGGAGCGGGCCATGTGCATGGCCATGCCCCCATCTCGGAGCAGGTGAAGTACGCCATCCTGGCGCAGCAGCTGAAGGCGCACAAGAACACggatctgctgcagcaggcgcTGGCCCACGGCTCCAGCAGCGTGGCCGGTGGCAATCCCCTGCTGCACTTTGGCTACGGCCCCCCACCCCAGGCACAgtcccacgcccacgcccacgcccactcgcACCACGCCCACTCGCACGCTCAGTCTGGCTCCCATCTGCCGCATCTGGTGAATGGGACAATGcagaatggcaatggcaatgggaatgggaatgggaatggaatcgGTGGGCAGGTGAATGCCATCGATGACGACGAGCCCAAGCTGATCATtgacgaggatgaggatggcgagggcgatggcgatggcgatgtgGAGGAGTTCGATGACgatgaagaggaggaggaggaggatgagccCGAGGACGAGGAGCACGACCAGGAGCCAATGGAAGAGTCggagcagccagagccagaggaggagcaggagctgtcCAAGCCCCTGGAGCAGACCAGTTCTGCCGCGGCCAATGAGGCGGCCAAGAAGATGGCCGATACCATCCTTGAGCAGGTGATGAaggcgggtgcgggtgcgggtgcgggcaaggccacgcccactgccactgttACGCCCATGAGCACGCGCACGCCCTCGCCGTCGCCGAATCCCTCGGATGAGCCGATGCCGAGCAACGCCGGAGCAATGCCAGAGCCGAGTCCACCGAATCCGACGATGAAGTCGATGATCGCCCAGGCCGAGTCGGTGGCCAAGTCGCTGAAGGAGGTGGCCAGCTCGCCGTTCAAGGACGAGTCGCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCGACCAGCAGCCAGATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTGGTGGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACGGAGGAcgtgaccagcagcagctccggcAGCGAGCCAAAGAAGAAGTCCGCCTACAGCCTGGCCCCCAATCGCGTCTCCTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCCCTGCGGCGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACAAAGAGCAACTGCGACCGGCACCTGCTGCGCAAGCACGGCAACGTCGAGTCGGCCATGTCCGTCTACGTGCCCACAGAGGACGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTGGAGGAGAtcgagctggaggagcagcgtCGCCGCCAGGAGGCGGAGCGCGAAcgggagctgcagctggagcgggAGCGCGAGAAGGAGCTGGAGCGCGAACGGGAGCTGGAGCGGGAGCGCGAAAAGGAGCGACTGCTGCTCATCCAGAAGCTGGCGGCACAGATGaatgccgctgcagctgctgccgccgccgctgctgcctctgcctctgcctcgtcCGATCCTGGCGCTGGCGGAGATCTGCCGTACAAGTGCCACCTGTGCGAGGGCTCGTTCGCCGAGCGGCTGCACTGCCTCGAGCACATCAAGCAGTCGCATGCCCACGACTTTGCCCTGCTCCTGGCCAAGGGAGCCATCGAGCCGGAGTCGACGCCGGCCCGTGGCGGCGGTGAGTCCAACCACCAGCCGCAGAGCACCAGCACCCCGGGCGCCGGCTCCGACGATGAGGCGagtggcggcggtggccgCGGCGCCTCCGGCAAGTATCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCCTGCGCCGCTTCTGGTCCACCGAGGACCTGCGCCGCCACATGCGCACCCACTCCGGGGAGCGGCCGTTCCAGTGCGAGATCTGTCTGCGCAAGTTCACCCTCAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGTGGACGCGCCCACAATGGCGACAATCCTGGCTCCGACTGCTCTGACGATGAGCAGGTCGCCACACCGCCATCCACACCGGGACCCAACCCACCGGCAgcggccaccaccaccaacaacaacaacagctgccagaacaacaacaacaacaataacagcagcaacgcCAATGCCAATTCGAAAATGGGTCTGCGTCTGCCGAAGCTGCACGAGCTGCTGGACAAGTCGAGCGAGTGGCGGGCGAGCCGTTTGGGCGAGCACAAGGAGAACATTGGAGAGGCGGCAACACCCTCAGTGGCCGCGTCGGTGGCCAGCTCCGATCTGATTGGCAATCTGCTGGGCATCAGCGACCAGGGCATACTCAACAAGCTGCTCTCCTCCGCCGACGAGGCGGCCAAGCTGCTGGGCGTGGACAACAAGTAG
Protein Sequence
MLAAQQQQQPHSTATATATATATATAAVVTQAAMERQRRESTTSESSLEHLDLGRTPKKLSSSSGPQPTSTPHDTAPAAAVMSASRKRKLRQHQQLQQQQQDLHSDDEEEEEEEEPRPLEETMAAVQRPRHKQRRNANASAAASASIVMDYSAGDASSLRKKFRLNRSGAAANGDLSESGFVDASSYNSSSQAAAAAVSAAAQQASNASSSSSSNSSGSGSSGASSPEGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENYTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQSTTQSSAAAQSGGSQSQSQQQRRLSQQQHQQQQQQSLAQSLAQSQHGGGAGHPGRAESYESDASCSTDVSSAHSHGSSNNNNNNNNNPHKANNNNSSSSISHSHKQQLQLQIQERIKQRRPKTTINNNNNNNIIMDEGSQAEEEEEDADVEERDMKEEQPDPDTDEDVAMPLSITSTPDVATLLAGVSASSRAESRSRSPSPAMPLLSCPACGASDFDTLPGLCAHLDARHSDIPAKCRDCEVIFASHRQLQAHFCRGLVGVDLPPMLGASSSPLHQGDDEDDEEAEDEDKDEARTEREAEQRDEFFQQLYLKGKAAAAAAAAAGASSPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDQEEEAQDVFTSEFRRMKLRGEFPCKLCAAVFPNLRALKGHNRVHLGSVGPSGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEDSKSRLGLGDDLADLSFRSISPPPPPPPPPPSSSCSAPIAEGGSQLKHMLLGESSPSPLPHAPTAVAAAAAAAAAGPPSKIQVKSLDQLVDKKQESPALDFSMDVLDLSKKPTAGGASASGLGLGLGSGSAATAPATVPELSAVLEQQQQQQQQQQQLLLAQQQFFGGAAGAAAAGGAGDAASQYMQQLFRNLMFQSQTPGFPFFGFMAPPPPQGSAEKQPQLSPPNRMGGLPLPMPGVGVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAVAAAAAAAAAMSQGGSGAGHVHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGGNPLLHFGYGPPPQAQSHAHAHAHSHHAHSHAQSGSHLPHLVNGTMQNGNGNGNGNGNGIGGQVNAIDDDEPKLIIDEDEDGEGDGDGDVEEFDDDEEEEEEDEPEDEEHDQEPMEESEQPEPEEEQELSKPLEQTSSAAANEAAKKMADTILEQVMKAGAGAGAGKATPTATVTPMSTRTPSPSPNPSDEPMPSNAGAMPEPSPPNPTMKSMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSSQMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERELQLEREREKELERERELEREREKERLLLIQKLAAQMNAAAAAAAAAAASASASSDPGAGGDLPYKCHLCEGSFAERLHCLEHIKQSHAHDFALLLAKGAIEPESTPARGGGESNHQPQSTSTPGAGSDDEASGGGGRGASGKYPDYSNRKVICAFCLRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRAHNGDNPGSDCSDDEQVATPPSTPGPNPPAAATTTNNNNSCQNNNNNNNSSNANANSKMGLRLPKLHELLDKSSEWRASRLGEHKENIGEAATPSVAASVASSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00474019;
90% Identity
-
80% Identity
-