Basic Information

Insect: Drosophila pseudoobscura
Gene Symbol: RREB1
Assembly: GCA_009870125.2
Location: CM020872.1:1960452-1966645[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.037 2.8 8.7 0.8 1 21 240 260 240 262 0.93

2 12 0.00026 0.019 15.5 0.2 1 23 272 294 272 294 0.98

3 12 8.3e-05 0.0063 17.1 7.3 1 23 300 322 300 322 0.98

4 12 0.65 49 4.8 3.8 2 19 566 583 566 585 0.97

5 12 0.042 3.1 8.6 0.0 1 23 732 754 732 754 0.97

6 12 1.3e-05 0.00095 19.6 0.7 1 23 764 786 764 786 0.99

7 12 0.00085 0.064 13.9 2.0 1 23 792 815 792 815 0.97

8 12 0.003 0.23 12.2 2.0 1 23 1095 1118 1095 1118 0.95

9 12 8.8e-05 0.0067 17.0 0.3 2 23 1508 1529 1507 1529 0.97

10 12 0.15 11 6.8 6.3 1 23 1535 1558 1535 1558 0.97

11 12 0.012 0.93 10.2 0.6 3 23 1759 1779 1757 1779 0.95

12 12 0.0014 0.1 13.2 4.8 1 23 1785 1807 1785 1807 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.037	2.8	8.7	0.8	1	21	240	260	240	262	0.93
2	12	0.00026	0.019	15.5	0.2	1	23	272	294	272	294	0.98
3	12	8.3e-05	0.0063	17.1	7.3	1	23	300	322	300	322	0.98
4	12	0.65	49	4.8	3.8	2	19	566	583	566	585	0.97
5	12	0.042	3.1	8.6	0.0	1	23	732	754	732	754	0.97
6	12	1.3e-05	0.00095	19.6	0.7	1	23	764	786	764	786	0.99
7	12	0.00085	0.064	13.9	2.0	1	23	792	815	792	815	0.97
8	12	0.003	0.23	12.2	2.0	1	23	1095	1118	1095	1118	0.95
9	12	8.8e-05	0.0067	17.0	0.3	2	23	1508	1529	1507	1529	0.97
10	12	0.15	11	6.8	6.3	1	23	1535	1558	1535	1558	0.97
11	12	0.012	0.93	10.2	0.6	3	23	1759	1779	1757	1779	0.95
12	12	0.0014	0.1	13.2	4.8	1	23	1785	1807	1785	1807	0.99

Sequence Information

Coding Sequence: ATGCTGGcagcccagcaacagcagcagcagcagcccccccAGCCACACAGCAGTGCCACCGGCGCCGTCACGCAGGCAGCGATGGAGCGCCAGCGACGCGAGTCCACCACATCGGAGTCCTCGCTGGAGCACCTCGACCTCGGCCGCACACCAAAGAagctgagcagcagcagcggcccaCAGCCCACATCGACGCCGCACGACACGGCTACAGCGTCGGCGGTGGTGTCGGCGTCGCGCAAGCGCAAGCTGCgacagcaccaacagcaacagcaacagcagcagcagcaggatctgctcagcgacgacgaggaggaggaggagccgcgTCCGCTTGAGGAGACGATGGCAGTGCAGCGGCCGCGCCACAAGCAGCGACGCAACGGCCCCGCCTccgcggcggcggccagcGCCAGCATCGTGATGGACTACAGTGCCGGCGACGCCAGTTCGCTTCGCAAGAAGTTCCGGCTGAACCGCAGCGGTGCCAACGGCGACCTCTCCGAGTCCGGGTTCGTCGACGCCAGTagctacaacaacagccaTGCCGCATTGGCCGTCGTCTCTGCTGCAGCGCAGCAGGCGTCGAATGcctccagcaccagcagcagcaacagcagtggcagcggaaGTGGCAGCTCTGGCGCCTCCTCGCCGGAGGGTCTGTGCCTGTCCAGCGGCGAGTCCGGAATCGGGGCTGGCGACGAGCACATGAAGTACCTCTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTCACCAACCACATCAGGTGCCACAACTACGCCAACGGCGACACCGAGAACTACACCTGCCGCATCTGCTCCAAGGTGCTATCCTCGGCCTCGTCGCTGGACAGACACGTGCTGGTGCACACAGGCGAGCGTCCGTTTAACTGCCGCTACTGCCACCTGACCTTCACCACCAACGGCAACATGCACCGCCACATGCGCACCCACAAGCAGCACcagtcgacgacgacgacgtcggcGGCGCAGCAGTCGGCTTCGCAGAGCGCCGGCAGCGGCTCtctgtcgcagtcgcagcagcagcagcagcgacgcctgtcacagcagcagcaacagcagcaacagtcgctgtcgcagcaccagcagcagggagGTGCAGGGCATCCGGGACGTGCGGAGAGCTATGAGAGCGATGCCAGCTGCTCCACGGATGTATCCAGTGcccacagccacacccacagccaTGGGAGTAgtcacgcccacgcccacgcacacgcacacagcaacaacaaccacaacaacaacaacaatcccCACAAAGCGAACAACAACCACAaggagatgcagcagcagatccagGAGCGGATCAAGCAGCGTCGCCCCAAGACCAccataaacaacaacaacataatcGACGAGGGCTCccaggcggaggaggaggaggatcgTGATCgggaggagcaggaccaggaccaggaggaggagcacccCGATGCGGACACTGACGATGATGTGGCCATGCCCCTCTCCATTACGAGCACCCCGGATGTGGCCACCCTGCTGGCCGGAGTCAACGGATCCTCGCGGGCAGCCTCGCGTTCCCGCTCCCCCTCGCCGGCCATGCCCCTGCTGAGCTGCCCCGCCTGTGGTGCCTCCGACTTTGACTCGCTGCCAGGGCTGTGCGCGCACCTGGACGCCCGCCACTCGGACATACCCGCCAAGTGCCGCGACTGCGACGTGATCTTCGCCAGCCACCGCCAGCTGCAGGCGCACTGCTGCCGCGGCCTGGTGGGCGTGGATCTACCGCCGCTCCTGGGGGCCAGCAGCTCACCGCTGCACCACagcgaggacgaggatgaaGAGGATGCCGACGACGAGGCGAGGACCGAGAGGGAGGCGGAACAGCACGGGGACTTCTTCCAGCAGCTGTATCTCAAGGGCAAGGCAGCCGCAGACGCGGCCGCAGCCGCCGGGACATCCACCTCCTCTCCACCGTCCCCCATCAAGCACGAGCCGGCGGACAGCAAGGACCTGGCGGACATCCAGAGCATCCTGAACAtgaccagctccagctgcaccTCCAGCTTCCTGCGCAACTTCGAGCAATCGGTGAACACGCCCTGCTCCAGCCAGTACAGCCTCGACGGCCGcgaccaggaggaggaggcccagGACGTCTTCACCTCGGAGTTCCGACGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCGCGGCAGTGTTCCCCAATCTGCGCGCCCTCAAGGGCCACAACCGGGTGCACCTCGGCTCCGTCGGCCCCTCCGGCCCGTTCCGCTGCAACATGTGTCCGTATGCCGTCTGCGACAAGGCCGCCCTCGTGCGTCACATGCGCACCCACAACGGGGACCGGCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGGCACCTGCGCAACCGTCACGGCAAGACCAGTCGCGAGGACGTGAAGCGGGCCATCGTCTACCATCCGGCGGAGGATGCCAGCTGCGAGGACAGCAAGTCGCGTCTGGGGCTCGGCGATGATCTGGCCGATCTGAGCTTCCGCTCGGTCTCGCCGCCacccccgccgccgccacccccAGCTAGTGCTCCGATCGCCGAGGGCTCTCAGCTGAAGCACATGCTCTTGGGAGAGCCGTCGCCTCCATTGCACACCCCCGCggtggccgctgctgctgctgccgttgccgggCCACCCTCCAAGATCCAGGTGAAGAGCCTCGACCAGCTGGTGGACAAGAAGCAGCCTGCCGCAGGCCCTGCCCTCGACTTTAGCATGGATGTGCTGGATCTCAGCAAGAAGCCAACAACAGGAGGATcctccaccgcctccgccccGTCGGGCCCGTCGACGGTGCCAGAGCTGGCAGCCGtcctggagcagcagcagcagcagcagcaacagcagcaacagcagcaacaacagctgctgctggcgcaaCAGCAGCTCTTTGGAGTAGCAGCCGGAGCGGCGGGAGCTGGCGATGCCACTTCCCAGTACATGCAGCAGCTGTTCCGCAACCTGATGTTCCAGTCGCAGACGCCGGGCTTTCCCTTCTTTGGGTTCATGGCCCCGCCGCCACCACAAAGCAATCCCGAGAAGCCGCCGCAGCTGAGTCCGCCTACGCGGATGGgcgccctgcccctgccgatGCCAGTGGGCGTGCCCGTGCCGCCTGGCGGCCCCGTCAAGATGGTCATCAAGAACGGAGTGCTGATGcccaagcagaagcagcgccGCTACCGCACCGAGCGGCCCTTCGCCTGCGAGCACTGCTCCGCCCGCTTCACGCTGCGCTCGAACATGGAGCGCCACgtgaagcagcagcatccccaGTTCTACGCCCAGCGGCAGCGGAGCGGACACCACGTGATGCGCGGTCGCGGAGCCTCCAATGCCGCAGCAGCCGtggccgcagccgccgccgcagcggcagccatGAGCCAGGGCGGATCCGGGTCGGGCCATGGGCACGGCCATGCCCCCATCTCGGACCAGGTGAAGTACGCCATTCTGACGCAACAGCTGAAGGCGCACAAGAACACGGATCTGCTGCAGCAGGCGCTGGCCCACGGATCCAGCAGCCTGGCCGGTGTCAATCCCCTCCTGCACTTTCCCTATGGCGCACCCCAGGCGCAGTTCCactcccagtcgcagtcccagtcccactcGAGTAGCCATGGCCATGCCAGTTCTGGGTCCCATCTGCCGCATCTGGTGAACGGGATGCACAATGGGCAGAACAACGGCCAGGCGAGTGCCATCGATGACGACGAACCCAAGCTGATCATtgacgaggatgaggatggcGAGGGCGATGTTGAGGAGTTCGACGAggacgaagaggaggaggaggacgagcccgaggacgaggacccggagccagagccaatgGAAGAGCCGAAGCAGGCCCACGACGAGGAGCCAGAggacgaggagcaggagctgcccAAGCCCCTGGAGCACATCTCCCAGACCAGTGCTGCAGCGGCCCATGAGGCGGCCAATGAGGCGGCCAAGAAGATGGCCGAGACCATCCTCGAGCAGGCCATCAAGGCGGGCAAGGCCACGCCCagcgccactgccactggcacgcCCATGAGCACGCGCACGCCGTCCCCCAGTCCGGAGCCGACGAGCAACGCGATGCCGGAGCCGAGTCCGCCGAATCCCACCATGAAGTCGATGATCGCCCAGGCCGAGTCGGTGGCCAAGTCCCTGAAGGAGGTCGCCAGCTCCCCGTTCAAGGACGAGTCGCAGGACCTGGTGCCGGTGGCCAAGCTGGTAGACAACGCCACCAGCAGCCAGATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTCGTGGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGAACGGAGGAcgtcaccagcagcagctccggcAGCGAGCCGAAGAAGAAGTCCGCCTACAGCCTGGCCCCCAATCGCGTCTCCTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGGCGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACCAAGAGCAACTGTGACCGCCATCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATACCAGTGCCCAAGTCTGTGGAGGAGAtcgagctggaggagcagagACGCCGCCAGGAGGCGGAGAGGGAGCGCGAACGCGAGCgggagctggaactggagctggagcgggaGCGCGAGAAGGAGCTGGAGCGCGAACGGGAgctggagcgggagcgggagcgcgAGCGCGAGCTCGAAAAGGAGCGCCTGGTGCTCATCCAGAAGCTGGCGGCTCAGATAAATGCCacggccgctgctgcctcgGCGGCCGATGCCGGCGCTGGCGGAGATCTGCCGTACAAGTGCCACCTGTGCGAAGGCTCCTTTGCCGAGCGTCTGCACTGCCTCGAGCACATCAAACAGTCGCATGCCCACGACTTTGCCCTGCTCCTGGCCAAGGGAGCCATCGAGCCGGAGTCCCGTGCCGGTGAGTCCAACCTCCAGCatctcctgcagcagcagagcaccCCGGGGGCCGGCTCCGATGATGAGGcgagcggcggcggcggtgcaCGCGGAGCCTCTGGCAAATATCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCCTGCGCCGCTTCTGGTCCACCGAGGACCTGCGCCGCCACATGCGCACCCACTCCGGGGAGAGGCCGTTCCAGTGCGAGATCTGCCTCCGCAAGTTCACCCTCAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGCGGACGAGCCCACAACGGCGACAATCCTGGCTCCGACTGCTCCGACGATGAGCAGGTCGCCACTCCTCCATCCACCCCAGGACCCACTCCGGCACCGGCCACCGGCACCACCCCCATAcccaccaacaacaataacagttgccagaacaacaacaacaacaacagcagcaacaccaacgcCAATGCAAAGACGGTTCTGCGCCAGCCGATGCTGCAAAAAATGCTGCTGGACAATTCGAGCGAGTGGCGGGCCAGCCGCCTGGGCGAGCACAAGGAGAACATCGGAGAGGCGGCAACCCCGTCAGCCGCGGCGGTGGCCAGCTCCGATCTGATCGGAAATCTCCTGGGCATCAGCGACCAGGGCATACTCAACAAGCTGCTCTCCTCCGCCGACGAGGCGGCCAAGCTCCTGGGAGTGGACAACAAGTAG
Protein Sequence: MLAAQQQQQQQPPQPHSSATGAVTQAAMERQRRESTTSESSLEHLDLGRTPKKLSSSSGPQPTSTPHDTATASAVVSASRKRKLRQHQQQQQQQQQQDLLSDDEEEEEPRPLEETMAVQRPRHKQRRNGPASAAAASASIVMDYSAGDASSLRKKFRLNRSGANGDLSESGFVDASSYNNSHAALAVVSAAAQQASNASSTSSSNSSGSGSGSSGASSPEGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENYTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQSTTTTSAAQQSASQSAGSGSLSQSQQQQQRRLSQQQQQQQQSLSQHQQQGGAGHPGRAESYESDASCSTDVSSAHSHTHSHGSSHAHAHAHAHSNNNHNNNNNPHKANNNHKEMQQQIQERIKQRRPKTTINNNNIIDEGSQAEEEEDRDREEQDQDQEEEHPDADTDDDVAMPLSITSTPDVATLLAGVNGSSRAASRSRSPSPAMPLLSCPACGASDFDSLPGLCAHLDARHSDIPAKCRDCDVIFASHRQLQAHCCRGLVGVDLPPLLGASSSPLHHSEDEDEEDADDEARTEREAEQHGDFFQQLYLKGKAAADAAAAAGTSTSSPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDQEEEAQDVFTSEFRRMKLRGEFPCKLCAAVFPNLRALKGHNRVHLGSVGPSGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEDSKSRLGLGDDLADLSFRSVSPPPPPPPPPASAPIAEGSQLKHMLLGEPSPPLHTPAVAAAAAAVAGPPSKIQVKSLDQLVDKKQPAAGPALDFSMDVLDLSKKPTTGGSSTASAPSGPSTVPELAAVLEQQQQQQQQQQQQQQQLLLAQQQLFGVAAGAAGAGDATSQYMQQLFRNLMFQSQTPGFPFFGFMAPPPPQSNPEKPPQLSPPTRMGALPLPMPVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAVAAAAAAAAAMSQGGSGSGHGHGHAPISDQVKYAILTQQLKAHKNTDLLQQALAHGSSSLAGVNPLLHFPYGAPQAQFHSQSQSQSHSSSHGHASSGSHLPHLVNGMHNGQNNGQASAIDDDEPKLIIDEDEDGEGDVEEFDEDEEEEEDEPEDEDPEPEPMEEPKQAHDEEPEDEEQELPKPLEHISQTSAAAAHEAANEAAKKMAETILEQAIKAGKATPSATATGTPMSTRTPSPSPEPTSNAMPEPSPPNPTMKSMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSSQMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERERELELELEREREKELERERELERERERERELEKERLVLIQKLAAQINATAAAASAADAGAGGDLPYKCHLCEGSFAERLHCLEHIKQSHAHDFALLLAKGAIEPESRAGESNLQHLLQQQSTPGAGSDDEASGGGGARGASGKYPDYSNRKVICAFCLRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRAHNGDNPGSDCSDDEQVATPPSTPGPTPAPATGTTPIPTNNNNSCQNNNNNNSSNTNANAKTVLRQPMLQKMLLDNSSEWRASRLGEHKENIGEAATPSAAAVASSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00474019;
90% Identity: iTF_00474019;
80% Identity: -