Basic Information

Insect: Drosophila athabasca
Gene Symbol: RREB1
Assembly: GCA_008121215.1
Location: CM017796.1:18651246-18659613[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.031 2.1 8.7 0.8 1 21 275 295 275 297 0.93

2 12 0.00022 0.015 15.5 0.2 1 23 307 329 307 329 0.98

3 12 7e-05 0.0047 17.0 7.3 1 23 335 357 335 357 0.98

4 12 0.55 37 4.8 3.8 2 19 601 618 601 620 0.97

5 12 0.035 2.4 8.5 0.0 1 23 765 787 765 787 0.97

6 12 1.1e-05 0.00072 19.6 0.7 1 23 797 819 797 819 0.99

7 12 0.00072 0.049 13.9 2.0 1 23 825 848 825 848 0.97

8 12 0.0026 0.17 12.1 2.0 1 23 1134 1157 1134 1157 0.95

9 12 7.4e-05 0.0051 17.0 0.3 2 23 1551 1572 1550 1572 0.97

10 12 0.12 8.5 6.8 6.3 1 23 1578 1601 1578 1601 0.97

11 12 0.01 0.7 10.2 0.6 3 23 1802 1822 1800 1822 0.95

12 12 0.0012 0.078 13.2 4.8 1 23 1828 1850 1828 1850 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.031	2.1	8.7	0.8	1	21	275	295	275	297	0.93
2	12	0.00022	0.015	15.5	0.2	1	23	307	329	307	329	0.98
3	12	7e-05	0.0047	17.0	7.3	1	23	335	357	335	357	0.98
4	12	0.55	37	4.8	3.8	2	19	601	618	601	620	0.97
5	12	0.035	2.4	8.5	0.0	1	23	765	787	765	787	0.97
6	12	1.1e-05	0.00072	19.6	0.7	1	23	797	819	797	819	0.99
7	12	0.00072	0.049	13.9	2.0	1	23	825	848	825	848	0.97
8	12	0.0026	0.17	12.1	2.0	1	23	1134	1157	1134	1157	0.95
9	12	7.4e-05	0.0051	17.0	0.3	2	23	1551	1572	1550	1572	0.97
10	12	0.12	8.5	6.8	6.3	1	23	1578	1601	1578	1601	0.97
11	12	0.01	0.7	10.2	0.6	3	23	1802	1822	1800	1822	0.95
12	12	0.0012	0.078	13.2	4.8	1	23	1828	1850	1828	1850	0.99

Sequence Information

Coding Sequence: GGGAAATGCCGCCGCAACTACGAAAATAATCAGCAAAGCACCATTCAAAGTCGAAACCCCAATCGACATCCACATCGATCTCAGTGCAGCAGAGTAAAAAGCAGCAAAATgctagcagcacagcagcagcagcagcagccaacccAGCCACACAGCAGTGCCACCGCCGCCTCCGTCACACAGGCTGCGATGGAGCGCCAGCGACGCGAGTCCACCACATCGGAGTCCTCGCTGGAGCATCTCGACCTTGGCCGCACACCAAAGAagcttagcagcagcagcggcccaCAGCCCACATCGACGCCGCACGACACGGTCACAGCGTCCGCGGTGGTGTCAGCGTCACGCAAGCGGAAGCTGcgacagcaccagcaccaactgcagcagcaccagcagcaggatcTGCTCagcgacgacgaggaggaggaggagctgcgtCCTCTGGAGGAGACGATGGCAGTGCAACGGCCGCGCCACAAGCAGCGACGCAACGGCCCCGCCTCCGCGGCGGCGGCCAGCGCCAGCATCGTGATGGACTACAGTGCCGGCGATGCCAGTTCGCTGCGCAAGAAGTTCCGGTTGAACCGCAGCGGCGCCAATGGAGACCTCTCGGAGTCCGGATTCGTCGATGCGAGCAGCTACAACAACAGCCAGGCCGCAGCGGCCGCCGTCTCTGCTGCAGCGCAGCAGGCGTCGAAtgcctccagcagcagcagtagcagcagtggcagcggcagcggaagCTCGGGCGCCTCCTCGCCAGAGGGCCTGTGCCTGTCCAGCGGCGAGTCCGGCATCGGGGCTGGCGACGAGCACATGAAGTACCTTTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTCACCAACCACATCAGGTGCCACAACTACGCCAACGGCGACACCGAGAACTACACCTGCCGCATCTGCTCCAAGGTGCTCTCCTCGGCCTCATCGCTAGACAGACACGTGCTGGTGCACACGGGCGAGCGTCCGTTCAACTGCCGCTACTGCCACCTGACCTTCACCACCAACGGCAACATGCACCGCCACATGCGCACCCACAAGCAGCACCAGTCGACGACGTCGGCAGCGCAGCAATCGGCTTCGCAGAGCgccagcggcggcggcggcggctctctgtcgcagtcgcagcagcagcgacgcctctcacagcagcagcagcaacaccagcagcagtcgctgtcgcagcagcagcaccagggTGGTGCAGCAGGTCATCCGGGACGTGCGGAGAGCTATGAGAGCGATGCCAGCTGTTCCACGGATGTTTCCAGTGCCCACAGCCACACCCATAGCCATGGTAGTAGTCAcgcccgctcccgctcccgcgcccactcccacaccaacaacaataacaatccCCATAAAGCGAACAACAACCACAAggagatgcagcagcagcagcagcagcagcagatccagGAGCGGATCAAGCAGCGTCGCCCCAAGACcaccatcaacaacaacatcatcgACGATGGCTCCCACGCGGAGGAGGACGAAGAGGAGCGTGACGAtcgggagggggaggaggagcatCACGATCCGGACACCGAAGATGATGTGGCCATGCCCCTCTCCATTACGAGCACCCCGGATGTGGCCACCCTGCTGGCCGGAGTCAATGCATCCTCGCGGGCTGCCTCGCGCTCCCGCTCACCCTCGCCGGCCATGCCCCTGCTGAGCTGCCCTGCTTGTGGCGCCTCCGACTTTGATTCGCTGCCAGGGCTGTGCGCCCACCTGGACGCCCGACACTCGGACATACCCGCCAAGTGCCGCGACTGTGACGTGATCTTCGCCAGCCACCGCCAGCTGCAGGCGCACTGCTGCCGCGGCCTGGTGGGGGTGGATCTGCCGCCGCTCCTGGGGGCCAGCAGCTCACCGCTACACCAGGGCGAGGATGAGGACGACGAGGATGCCGAGGACGAGGCCAGAACCGAGAGGGAGGCCGAACAGCACGGAGACTTCTTCCAGCAACTGTACCTCAAGAGCAaggcagccgctgccgctgtcgccgGGGCATCCACCTCCTCGCCCCCGTCCCCCATCAAGCACGAGCCGGCGGACAGCAAGGACCTGGCTGACATCCAGAGCATCCTCAACATGACGAGCTCCAGCTGCACCTCCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAGTACAGCCTCGACGGCCGcgaccaggaggaggaggcccaAGATGTTTTCACTTCGGAGTTCCGCCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGTGCGGCAGTGTTCCCCAATCTGCGCGCCCTCAAGGGCCACAACCGGGTGCATCTCGGCTCCGTTGGCCCCTCCGGTCCGTTCCGTTGCAACATGTGTCCGTATGCCGTCTGCGACAAGGCCGCCCTCGTCCGTCACATGCGCACCCACAACGGGGACCGACCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGGCATCTGCGCAACCGGCACGGCAAGACCAGTCGCGAGGACGTGAAGCGGGCCATCGTCTACCATCCGGCGGAGGACGCCAGCTGCGAGGACAGCAAGTCGCGCCTGGGGCTCGGCGATGATCTGGCCGATCTGAGCTTCCGCTCGGTGTCGCCGcccccaccgccaccgccggcCCCAACCAGTGCTCCGATTACCGAGGGCTCACAACTGAAGCACATGCTCCTGGGAGAGCCGTCGCCACCATTGCATACTCCCACAgtggccgctgctgctgctgctgctgctgctgttgccggaCCACCATCCAAGATCCAAGTGAAGAGCCTCGACCAGTTGGTGGACAAGAAACAGCCTGCCGCTGGCCCTGCCCTCGACTTTAGCATGGATGTGCTGGATCTCAGCAAGAAGCCCAACACTGGAGGATCAGCCTCGGCttctgcctccgcctctgcctcgtCGGCCCCCTCAACGGTGCCAGAACTGGCTGCCGttctggagcagcagcaacaacaacagcagcagcagcagcagcaacagctgctcctggcccagcagcagctctttGGTGGTGCAGCCGGAGCAGCGGGAGCAGCAGGCGATGCCGCCTCCCAGTACATGCAGCAGCTGTTCCGCAACCTGATGTTCCAAACCCAGACACCGGGCTTTCCCTTCTTCGGATTCATGGCCCCGCCTCCACCACAAGGCAGTGCCGAGAAGCCGCCGCAGCTGAGTCCGCCATCGCGGATGGGGACCCTGCCCCTGCCGATGCCAGTGGGCGTGCCCGTTCCGTCTGGCGGCCCCGTCAAGATGGTCATCAAGAACGGAGTGCTGATGCCCAAACAGAAACAACGCCGCTACCGCACCGAACGGCCCTTCGCCTGCGAGCACTGCTCGGCCCGCTTCACTCTGCGCTCCAACATGGAGCGTCAcgtgaagcagcagcatccccaGTTCTATGCCCAGCGCCAGCGGAGCGGACACCACGTGATGCGCGGACGCGGTGCCTCCAACGCCGCAGCGGCCGTggccgcagccgccgccgcagcggcagccatGAGCCAGGGCGGATCCGGAGCGGGCCATGTGCACGGCCATGCCCCCATCTCGGAGCAGGTGAAGTACGCCATCCTGGCGCAACAGCTGAAGTCGCACAAGAACACGGATCTGCTGCAGCAGGCTCTGGCACACGGATCCAGCAGCGTGGCCGGTGGCAATCCCCTTCTGCACTTTGGCTATGGCCCTCCCCAGACGCAGTCGCACTCCCAGTCACAGTCCCACAACCACACCCCATCccactcccagtcccagtcgagTACCCATGGCCATGCTCAGTCCAGTTCTGGCTCCCATCTGCCGCATCTGGTGAATGGGATCCACAATGGGAGCAATGGGAACAACGGCCAGGCGAGTGCCATCGATGACGACGAGCCCAAGCTGATCATtgacgaggatgaggatggcGAGGGCGATGTGGAGGAGTTCGACGAggacgatgaggaggaggaggatgagcccgaggacgaggacccggagccagagccaatgGAAGAGCCGGAACAGGTGCACGACGAGGAGCCAGAGGACGATGATCAGGAGCTGCCCAAGCCATTGGAGCACATCTCACAGCCCAGTGCTGCAGCGGCCAATGAGGCGGCCAAGAAGATGGCCGAGACAATTCTCGAGAAGGCCATCAAGGCGGGCAAGGCCACGCCCACTGCCACGCCCATGAGCACGCGCACGCCGTCACCCAGTCCGGAGCCGACGAACAACGCCATGCCGGAGCCGAGTCCCCCGAATCCCACCATGAAGTCGATGATCGCCCAGGCCGAGTCGGTGGCCAAGTCTCTGAAGGAGGTCGCCAGCTCTCCGTTCAAGGACGAGTCGCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCAGCCAGATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGATGAGGAGGGTCTCGTGGCCTCCGGAAGCGCCAGCGAAAGCAACAATTCCGGAACGGAGGACgtcaccagcagcagttccGGCAGCGAACCGAAGAAGAAGTCCGCCTACAGCCTGGCCCCCAATCGCGTCTCGTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGACGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCACTGCTCTTCACCACCAAGAGCAACTGTGACCGCCATCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTGGAGGAGATCGAGCTCGAGGAGCAGCGTCGTCGCCAAGAGGCGGAGAGGGAACGCGAACGCGAGCGGGAgttggaactggaactggaacggGAGCGCGAGAAGGAGCTGGAGCGCGAACGAGAACTGGAGCGGGAGCGCGAGCGCGAGAAGGAGCGTCTGGTGCTCATCCAGAAGCTGGCGGCTCAGATGAAtgccgccgcagccgccgctgctgctgcctcggcTACCGATGCCGGCGCTGGCGGAGATCTGCCGTACAAGTGCCACCTGTGCGAGGGCTCCTTTGCCGAGCGTCTGCACTGCCTCGAGCACATCAAGCAGACGCATGCCCACGAGTTTgccctgctgctggccaagggAGCCATCGAACCGGAGTCCCGTGCCGGGGAGTCCAACCACCAGCAGCtgctccaacagcagcagagcaccCCGGGCGCCGGTTCCGACGATGAGGCgagtggcggtggcggtgcaCGCGGTGCCTCTGGCAAATATCCCGACTACAGCAACCGCAAGGTGATCTGCGCATTCTGTCTGCGTCGCTTCTGGTCCACCGAGGACCTGCGCCGGCACATGCGCACCCATTCCGGGGAGCGGCCGTTCCAGTGCGAGATCTGCCTCCGCAAGTTCACCCTCAAGCACAGCATGCTGCGTCACATGAAGAAGCACAGCGGACGCGCCCACAACGGCGACAATCCCGGCTCCGACTGTTCCGACGATGAGCAGGTCGCCACTCCACCCTCCACCCCAGGACCCATTCCGGccacccccaccaccaacaacaacaacagttgccagaacaacaacaacaacaatagcagcaacaccaacgcCAATGCAAAGATGGGCCTGCGTCTGCCGAAGCTTCACGAGCTGCTGGACAAGTCGAGCGAGTGGCGGGCCAGCCGGCTGGGCGAGCACAAGGAGAACATCGGCGAGGCGGCAACACCGTCAGCCGCAGCGGTGGCCAGCTCCGATCTGATCGGAAATCTCCTGGGCATCAGCGACCAGGGCATACTCAACAAGCTGCTCTCATCCGCGGACGAGGCGGCTAAGTTCCTGGGCGTGGACAACAAGTAG
Protein Sequence: GKCRRNYENNQQSTIQSRNPNRHPHRSQCSRVKSSKMLAAQQQQQQPTQPHSSATAASVTQAAMERQRRESTTSESSLEHLDLGRTPKKLSSSSGPQPTSTPHDTVTASAVVSASRKRKLRQHQHQLQQHQQQDLLSDDEEEEELRPLEETMAVQRPRHKQRRNGPASAAAASASIVMDYSAGDASSLRKKFRLNRSGANGDLSESGFVDASSYNNSQAAAAAVSAAAQQASNASSSSSSSSGSGSGSSGASSPEGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENYTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQSTTSAAQQSASQSASGGGGGSLSQSQQQRRLSQQQQQHQQQSLSQQQHQGGAAGHPGRAESYESDASCSTDVSSAHSHTHSHGSSHARSRSRAHSHTNNNNNPHKANNNHKEMQQQQQQQQIQERIKQRRPKTTINNNIIDDGSHAEEDEEERDDREGEEEHHDPDTEDDVAMPLSITSTPDVATLLAGVNASSRAASRSRSPSPAMPLLSCPACGASDFDSLPGLCAHLDARHSDIPAKCRDCDVIFASHRQLQAHCCRGLVGVDLPPLLGASSSPLHQGEDEDDEDAEDEARTEREAEQHGDFFQQLYLKSKAAAAAVAGASTSSPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDQEEEAQDVFTSEFRRMKLRGEFPCKLCAAVFPNLRALKGHNRVHLGSVGPSGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEDSKSRLGLGDDLADLSFRSVSPPPPPPPAPTSAPITEGSQLKHMLLGEPSPPLHTPTVAAAAAAAAAVAGPPSKIQVKSLDQLVDKKQPAAGPALDFSMDVLDLSKKPNTGGSASASASASASSAPSTVPELAAVLEQQQQQQQQQQQQQLLLAQQQLFGGAAGAAGAAGDAASQYMQQLFRNLMFQTQTPGFPFFGFMAPPPPQGSAEKPPQLSPPSRMGTLPLPMPVGVPVPSGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAVAAAAAAAAAMSQGGSGAGHVHGHAPISEQVKYAILAQQLKSHKNTDLLQQALAHGSSSVAGGNPLLHFGYGPPQTQSHSQSQSHNHTPSHSQSQSSTHGHAQSSSGSHLPHLVNGIHNGSNGNNGQASAIDDDEPKLIIDEDEDGEGDVEEFDEDDEEEEDEPEDEDPEPEPMEEPEQVHDEEPEDDDQELPKPLEHISQPSAAAANEAAKKMAETILEKAIKAGKATPTATPMSTRTPSPSPEPTNNAMPEPSPPNPTMKSMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSSQMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERERELELELEREREKELERERELEREREREKERLVLIQKLAAQMNAAAAAAAAASATDAGAGGDLPYKCHLCEGSFAERLHCLEHIKQTHAHEFALLLAKGAIEPESRAGESNHQQLLQQQQSTPGAGSDDEASGGGGARGASGKYPDYSNRKVICAFCLRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRAHNGDNPGSDCSDDEQVATPPSTPGPIPATPTTNNNNSCQNNNNNNSSNTNANAKMGLRLPKLHELLDKSSEWRASRLGEHKENIGEAATPSAAAVASSDLIGNLLGISDQGILNKLLSSADEAAKFLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00474019;
90% Identity: iTF_00474019;
80% Identity: -