Basic Information

Insect: Drosophila helvetica
Gene Symbol: RREB1
Assembly: GCA_963969585.1
Location: OZ018401.1:9492645-9499065[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.036 3.5 8.7 0.8 1 21 242 262 242 264 0.93

2 12 0.00025 0.024 15.5 0.2 1 23 274 296 274 296 0.98

3 12 8.2e-05 0.0078 17.0 7.3 1 23 302 324 302 324 0.98

4 12 0.64 61 4.8 3.8 2 19 586 603 586 605 0.97

5 12 0.041 3.9 8.5 0.0 1 23 752 774 752 774 0.97

6 12 1.2e-05 0.0012 19.6 0.7 1 23 784 806 784 806 0.99

7 12 0.00084 0.08 13.9 2.0 1 23 812 835 812 835 0.97

8 12 0.003 0.29 12.1 2.0 1 23 1119 1142 1119 1142 0.95

9 12 8.7e-05 0.0083 17.0 0.3 2 23 1540 1561 1539 1561 0.97

10 12 0.15 14 6.8 6.3 1 23 1567 1590 1567 1590 0.97

11 12 0.012 1.2 10.2 0.6 3 23 1794 1814 1792 1814 0.95

12 12 0.0014 0.13 13.2 4.8 1 23 1820 1842 1820 1842 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.036	3.5	8.7	0.8	1	21	242	262	242	264	0.93
2	12	0.00025	0.024	15.5	0.2	1	23	274	296	274	296	0.98
3	12	8.2e-05	0.0078	17.0	7.3	1	23	302	324	302	324	0.98
4	12	0.64	61	4.8	3.8	2	19	586	603	586	605	0.97
5	12	0.041	3.9	8.5	0.0	1	23	752	774	752	774	0.97
6	12	1.2e-05	0.0012	19.6	0.7	1	23	784	806	784	806	0.99
7	12	0.00084	0.08	13.9	2.0	1	23	812	835	812	835	0.97
8	12	0.003	0.29	12.1	2.0	1	23	1119	1142	1119	1142	0.95
9	12	8.7e-05	0.0083	17.0	0.3	2	23	1540	1561	1539	1561	0.97
10	12	0.15	14	6.8	6.3	1	23	1567	1590	1567	1590	0.97
11	12	0.012	1.2	10.2	0.6	3	23	1794	1814	1792	1814	0.95
12	12	0.0014	0.13	13.2	4.8	1	23	1820	1842	1820	1842	0.99

Sequence Information

Coding Sequence: ATGCTTGCAGcaccgcaacagcagcagcagcagccccccCAGCCACACAGCAGTGCCACCGCCGCCGTCGCACAGGCTGCGATGGAGCGCCAGCGACGCGAGTCCACCACGTCGGAGTCCTCGCTGGAGCATCTCGACCTCGGGCGCACACCAAAGaagctgagcagcagcagcggcccACAGCCCACATCGACGCCGCACGACACGACGGCCCCAGCGTCGGCGGTGGTGTCGGCGTCGCGCAAGCGCAAGCTGcgacagcaccagcagcatcagcagcagcagcaggatctGCTCAGCGACGacgaggaggaagaggagctGCGTCCGCTGGAGGAGACGATGCAGCGGCCGCGACACAAGCAGCGACGGAACGGCCCCGCCTCCGCGGCGGCGGCCAGCGCCAGCATCGTGATGGACTACAGTGCCGGCGATGCCAGTTCGCTGCGCAAGAAGTTCCGGCTGAACCGCAGCGGCGCCAACGGCGGCGACCTTTCGGAGTCCGGATTCGTCGACGCCAGCAGCTACAACAACAGCCATGCCGCAACGGCCGCCGTCTCGGCTGCAGCGCAGCAGGCGTCGAATGCctccagcagcagtagcagcagcagcaacagcagtggcagcggcagcggaagTGGCAGCTCGGGCGCCTCCTCGCCGGAGGGCCTGTGCCTGTCCAGCGGCGAGTCCGGAATCGGGGCTGGCGACGAGCACATGAAGTACCTCTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCCCACGAGTTCACCAACCACATCAGGTGCCACAACTACGCCAACGGCGACACCGAGAACTACACCTGCCGCATCTGCTCCAAGGTGCTCTCCTCGGCCTCATCGCTAGACAGACACGTGCTGGTGCACACGGGCGAGCGACCGTTCAACTGCCGCTACTGCCACCTGACCTTCACCACCAACGGCAACATGCACCGCCACATGCGCACCCACAAGCAGCACCAGTCGACGACGTCGGCAGCGCAGCAATCGGCTTCGCAGAGCgccagcggcggcggcggcggcggcagcggctctctgtcgcagtcgcagcagcagcgacgcctctcacagcagcagcagcagcaacagcagcagcagcagaagtcgctgtcgctgtcgcagCAGCACCAGGGTCCAGGTGCAGGCCATCCGGGACGGGCGGAGAGCTATGAGAGCGATGCCAGCTGCTCCACGGATGTATCCAGTGCCCACAGCCACACCCACAGCCATGGGAGTAGTCACGCCCGCGTCcgcgcccacgcccacgcacacgcacacgcccacaccaacaacaacaacaacaacaacaacaatcccCAAAAGGCGAACAACAACCACAAGGAgatgcagcagctgcagcagcagcagatccaTGAGCGGATCAAGCAGCGTCGCCCCAAGACCAccatcaacaacaacatcatcgACGATGGATCCCacgcggaggaggaggacgaagAGGAGCGCGATGAtcgggaggaggaggaggaggagaaggagcatCCCGATCCGGACAGCGAGGATGATGTAGCCATGCCCCTCTCCATAACGAGCACCCCGGACGTGGCCACCCTGCTGGCCGGAGTCAATGCATCCTCGCGGGCTGCCTCGCGCTCCCGCTCACCCTCACCGGCCATGCCCGTGCTGAGCTGCCCCGCCTGTGGCGCCTCCGACTTTGACTCGCTGCCCGGGCTGTGCGCCCACCTGGACGCCCGGCACTCGGACATACCCGCCAAGTGCCGCGACTGTGACGTGATCTTCGCCAGCCACCGCCAGCTGCAGGCGCACTGCTGCCGCGGCCTGGTGGGAGTGGATCTGCCGCCGCTCCTAGGGGCCAGCAGCTCGCCGCTGCACCACGGCGAGGATGAGGACGTGGAGGATGCCGAGGACGAGGCCAGGACCGAGAGGGAGGCCGAACAGCACGGCGACTTCTTCCAGCAGCTGTACCTCAAGAGCAAggcagccgctgccgctgccgtcgcCGCCGGGGCATCCGCCTCCTCGCCCCCGTCGCCGATCAAGCACGAGCCGGCGGACAGCAAGGACTTGGCTGACATCCAGAGCATCCTGAACATgaccagctccagctgcaccTCCAGCTTCCTGCGCAACTTTGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAGTACAGCCTCGACGGCCGCgaccaggaggaggaggcccaAGATGTCTTCACCTCGGAATTCCGGCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGTGCGGCAGTGTTCCCCAATCTGCGCGCCCTCAAGGGCCACAACCGGGTCCATCTCGGCTCCGTTGGCCCCTCCGGCCCGTTCCGCTGCAACATGTGTCCGTACGCCGTCTGCGACAAGGCCGCCCTCGTCCGCCACATGCGCACCCACAACGGGGACCGGCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGGCATCTGCGCAACCGCCACGGCAAGACCAGTCGCGAGGACGTGAAGCGGGCCATCGTCTACCATCCGGCGGAGGACGCCAGCTGCGAGGACAGCAAGTCGCGCCTCGGGCTCGGTGATGATCTGGCCGATCTGAGCTTCCGCTCGGTCTCGCCGcctccaccgccgccgccagccCCATCCAGTGCCCCGATTGCCGAGGGCTCACAGCTGAAGCACATGCTCCTCGGAGAGCCGTCGCCACCATTGCACACGCCCGCAGTGGCCGCggctgccgctgttgccgGACCACCGTCCAAGATCCAGGTGAAGAGCCTCGACCAGCTGGTGGACAAAAAGCAGCCTGCCGCTGGCCCTGCCCTCGACTTTACCATGGACGTGCTGGATCTCAGCAAGAAGCCGAGCACAGGAGgatctgcctctgcttctgcctctggctccgcctccgcctcgtCGGCCCCCTCAACGGTGCCCGAACTGGCTGCCGtcctggagcagcagcagcagcagcagcagcaacagctgctcctggcccagcagcagctctttGGCGGCGCAGCCGGAGCAGCGGGAGCAGGCGATGCCGCCTCCCAGTACATGCAGCAGCTGTTCCGCAGCCTGATGTTCCAGTCGCAGACGCAGACGGGCTTTCCGTTCTTCGGATTCATGGCCCCGCCACCACCACAAGGCAATCCCGAGAAGCCGCCGCAGCTGAGTCCGCCCACACGGATGGgggccctgcccctgcccctgccgatgcccgtgggcgtgggcgtgccCGTGCCGCCCGGCGGCCCCGTCAAGATGGTCATCAAGAACGGAGTGCTGATGCccaagcagaagcagcgcCGCTACCGCACCGAGCGGCCCTTCGCCTGCGAGCACTGCTCGGCCCGCTTCACCCTGCGCTCCAACATGGAGCGCCACgtgaagcagcagcatccccaGTTCTACGCCCAGCGCCAGCGGAGCGGACACCACGTGATGCGCGGACGCGGCGCCTCCAATGCCGCAGCGGCCgtagccgcagccgccgccgcagcgGCAGCCATGAGCCAGGGCGGGTCCGGAGCGGGCCATGTGCACGGCCATGCCCCCATCTCGGAGCAGGTGAAGTACGCCATCCTGGCGCAACAGCTCAAGTCGCACAAGAACACGGATCTGCTGCAGCAGGCCCTGGCCCACGGATCCAGCAGCGTGGCCGGCGGCAATCCCCTCCTGCACTTTGGCTATGGCCCGCCCCAGACGCCGTCCCACTCCCAGTCACAGGCCCACAGCcactcccagtcccagtcccactcCCAGTCCCACGCCCAGTCGAGTGCCCAGTCCAGTGCTGGCTCCCACCTGCCGCATCTGGTGAATGGGATCCACAATGGGAACAACGGGAACAACGGCCAGGCGAGTGCCATCGATGACGACGAGCCCAAGCTGATCATtgacgaggacgaggatggCGAGGGCGATGTGGAGGAGTTCGACGAGgacgatgaggaggaggaggatgagcCCGAGGACGAGGACCCGGAGCCCGAGCCAATGGAGGAGCCGGAACAGGCGCACGACGAGGAGCCAGAGGACGAGGATCAGGAGCTGCCCAAGCCCCTGGAGCACATCGCACAGCCCAgtgctgcagcggccaatgaGGCGGCCAAGAAGATGGCCGAGACCATTCTCGAGCAGGCCATCAAGGCGGGCAAGGCCAcgcccacagccacagccactgccacgcCCATGAGCACGCGCACGCCGTCACCCAGTCCGGAGCCGTCGAGCAACGCGATGCCGGAGCCGAGTCCGCCGAATCCCACCATGAAGTCGATGATCGCCCAGGCCGAGTCGGTGGCCAAGTCCCTGAAGGAGGTCGCCAGCTCGCCCTTCAAGGACGAGTCGCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCAGCCAGATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGTCTCGTGGCCTCCGGCAGCGCCAGCGAGAGCAACAATTCCGGAACGGAGGAcgtcaccagcagcagctccggCAGCGAGCCGAAGAAGAAGTCCGCCTACAGCCTGGCCCCCAATCGCGTCTCCTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACCAAGAGCAACTGCGACCGCCATCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTGGAGGAGATCGAGCTGGAGGAGCAGCGTCGCCGCCAGGaggcggagcgggagcgcGAACGCGAGCgcgagctggagctggaactggagcgggagcgcgaacgagagctggagctggagcgcGAACGGGAGCTGGAGCGGGAGCGCGAGCGCGAGAAGGAGCGTTTGGTGCTCATCCAGAAGCTGGCGGCCCAGATGAATGCCGCCGCagcggccgctgctgctgcctcggcAGCCGATGCCGGCGCTGGCGGAGATCTGCCGTACAAGTGCCACCTGTGCGAGGGCTCCTTTGCCGAGCGGCTGCACTGCCTCGAGCACATCAAGCAGACGCATGCCCACGAGTTCGccctgctgctggccaaggGCGCCATCGAGCCGGAGTCCCGTGCCGGGGAGTCCAACCACCAGCAgctcctgcagcagcagcagcagagcaccCCGGGCGCCGGCTCCGATGATGAGGCgagtggcggcggcggtgcaCGCGGCGCCTCTGGCAAGTATCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCCTGCGCCGCTTCTGGTCCACCGAGGACCTGCGCCGGCACATGCGCACCCACTCCGGCGAGCGGCCGTTCCAGTGCGAGATCTGCCTCCGCAAGTTCACCCTCAAGCACAGCATGCTGCGTCACATGAAGAAGCACAGCGGCCGCGCCCACAACGGCGACAATCCCGGCTCCGACTGCTCCGACGACGAGCAGGTGGCCACGCCTCCATCCACACCAGGACCCACTCCGGCCACccccaccaccgccaccgccaacaacaacaacagctgccagaacaacaacaacaacaacaacaacaacagcagcaacaccaacgccaacgccaatgCCAAGATGGGTCTGCGTCTGCCGAAGCTGCACGAGCTGCTGGACAAGTCGAGCGAGTGGCGGGCCAGCCGGCTGGGCGAGCACAAGGAGAACATCGGCGAGGCGGCAACACCGTCGGCCGCAGCCGTGGCCAGTTCCGATCTGATCGGCAATCTGCTGGGCATCAGCGACCAGGGCATACTCAACAAGCTGCTCTCGTCCGCCGACGAGGCGGCCAAGTTCCTGGGAGTGGACAACAAGTAG
Protein Sequence: MLAAPQQQQQQPPQPHSSATAAVAQAAMERQRRESTTSESSLEHLDLGRTPKKLSSSSGPQPTSTPHDTTAPASAVVSASRKRKLRQHQQHQQQQQDLLSDDEEEEELRPLEETMQRPRHKQRRNGPASAAAASASIVMDYSAGDASSLRKKFRLNRSGANGGDLSESGFVDASSYNNSHAATAAVSAAAQQASNASSSSSSSSNSSGSGSGSGSSGASSPEGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENYTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQSTTSAAQQSASQSASGGGGGGSGSLSQSQQQRRLSQQQQQQQQQQQKSLSLSQQHQGPGAGHPGRAESYESDASCSTDVSSAHSHTHSHGSSHARVRAHAHAHAHAHTNNNNNNNNNPQKANNNHKEMQQLQQQQIHERIKQRRPKTTINNNIIDDGSHAEEEDEEERDDREEEEEEKEHPDPDSEDDVAMPLSITSTPDVATLLAGVNASSRAASRSRSPSPAMPVLSCPACGASDFDSLPGLCAHLDARHSDIPAKCRDCDVIFASHRQLQAHCCRGLVGVDLPPLLGASSSPLHHGEDEDVEDAEDEARTEREAEQHGDFFQQLYLKSKAAAAAAVAAGASASSPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDQEEEAQDVFTSEFRRMKLRGEFPCKLCAAVFPNLRALKGHNRVHLGSVGPSGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEDSKSRLGLGDDLADLSFRSVSPPPPPPPAPSSAPIAEGSQLKHMLLGEPSPPLHTPAVAAAAAVAGPPSKIQVKSLDQLVDKKQPAAGPALDFTMDVLDLSKKPSTGGSASASASGSASASSAPSTVPELAAVLEQQQQQQQQQLLLAQQQLFGGAAGAAGAGDAASQYMQQLFRSLMFQSQTQTGFPFFGFMAPPPPQGNPEKPPQLSPPTRMGALPLPLPMPVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAVAAAAAAAAAMSQGGSGAGHVHGHAPISEQVKYAILAQQLKSHKNTDLLQQALAHGSSSVAGGNPLLHFGYGPPQTPSHSQSQAHSHSQSQSHSQSHAQSSAQSSAGSHLPHLVNGIHNGNNGNNGQASAIDDDEPKLIIDEDEDGEGDVEEFDEDDEEEEDEPEDEDPEPEPMEEPEQAHDEEPEDEDQELPKPLEHIAQPSAAAANEAAKKMAETILEQAIKAGKATPTATATATPMSTRTPSPSPEPSSNAMPEPSPPNPTMKSMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSSQMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERERELELELERERERELELERERELEREREREKERLVLIQKLAAQMNAAAAAAAAASAADAGAGGDLPYKCHLCEGSFAERLHCLEHIKQTHAHEFALLLAKGAIEPESRAGESNHQQLLQQQQQSTPGAGSDDEASGGGGARGASGKYPDYSNRKVICAFCLRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRAHNGDNPGSDCSDDEQVATPPSTPGPTPATPTTATANNNNSCQNNNNNNNNNSSNTNANANAKMGLRLPKLHELLDKSSEWRASRLGEHKENIGEAATPSAAAVASSDLIGNLLGISDQGILNKLLSSADEAAKFLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00474019;
90% Identity: iTF_00474019;
80% Identity: -